• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    Pyrimidine derivatives are provided wherein the 6-position carries the group OSO2NR5R6 and the 2-position carries the group NR1R2. R1 and R2 are preferably hydrogen or lower alkyl but both are not hydrogen and R5 and R6 are preferably lower alkyl, although these groups may form a cyclic ring. The 3-position and 4-position are preferably substituted with lower alkyl, although lower alkynyl or alkenyl may be used. The derivatives are compounded into compositions for combatting fungal pests.
    公开号:SU919580A3
    申请号:SU721832188
    申请日:1972-09-22
    公开日:1982-04-07
    发明作者:Мэри Коул Энн；Ангус Вильям Тернер Джон；Кеннет Снелл Брайан
    申请人:Империал Кемикал Индастриз Лимитед(Фирма)；
    IPC主号:
    专利说明:

    (5) AUNSPCHID COMPOSITION
    one
    This invention relates to chemical plant protection products, namely, fungicidal compositions based on pyrimidine derivatives.
    A fungicide is known, the active principle of which is 2-dimethylamine-6 methyl-4-pyrimidinyl-1-pyrrolidone 1.
    However, this fungicide is not sufficiently active against some species of fungi.
    A fungicide is also known, the active principle of which is 5 butyl-β-hydroxy-6-methyl-2-dimethylaminopyrimidine (dimetiriol) 2.
    However, at low concentrations, this fungicide is not sufficiently active.
    The aim of the invention is to find new fungicidal compositions with high fungicidal activity.
    This goal is achieved using fungicidal formulations, the active substance of which is a pyrimidine derivative of the formula
    R l 3-fnr 2 S "
    NRiH
    ten
    where Rn cannot simultaneously mean hydrogen and C -C-apkil or form pyrrolidine together with the nitrogen atom;
    IS
    C 1-Cx-alkyl;
    RXC is C-alkyl;
    : C-Cd-alkyl, allyl or
    5I together with the nitrogen atom - pyrrolidine, pipera30 ZIN, azepine, piperidine, morLoline,
    active substance concentration of 0.001-85 wt. /, the rest is additive. The proposed compounds are obtained by reacting the corresponding 6-hydroxypyrimidine with the sulfamoyl chloride derivative. Example. A method for the preparation of 5-butyl-2-dimethylamine-b-methyl-β-pyrimdinyl-pyrrolidone sulfonate is shown, having the formula: sodium (3.9 g) in ethanol (ml), 5 butyl-2-dimethylamino-oxy-6-methylpyrimidine (392.1 g) was added.
    The table is anhydrous ethyl acetate, part of which is distilled off in order to remove traces of Zanol. 300 g of 1-pyrrolidine sulfonyl chloride are added to the resulting oxide and the mixture is refluxed for several hours. After cooling and removal of insoluble substances by filtration, the filtrate is washed with sodium hydroxide solution and then with water until the washing water is neutral. After drying over anhydrous sodium sulphate, the volatile fraction is removed by evaporation under reduced pressure, and then traces of the solvent are removed by heating under vacuum. The non-distilled residual oil is 5-butyl-2-dimethylamine-6-methyl-pyrimidinyl-1-pyrrolidine sulfonate. In this way, the compounds shown in Table 1 are obtained. one.
    Continued table. one
    Forms of application of conventional emulsions, powders, granules. They are obtained by using obsity methods in the manufacture of pesticide formulations.
    Examples 1 and 2 confirm the biological activity of the proposed compounds.
    Example 1. Compounds are tested for various fungal diseases of foliage plants.
    The method of spraying the foliage of healthy plants with solutions of the tested compounds is used. All spray solutions contain 100, 25, S, 5
    and 1 hour / million test compound. Then the plants are infected with pathogens of the disease, which are being controlled, and after a few days, depending on the type of the disease, they are visually determined
    the results shown in table. 2 and 3, in which the degree of disease is determined according to the following scale:
    Evaluation of the disease,
    %
    O61-100
    about
    26-60
    1 6-25
    2 3 0-5.
    9919580
    Continued table. 3
    10 Continued table. 3
     Dispersible powder
    Dispersible powder
    Table 9
    ;
    Dispersible powder.
    Thus, the proposed compounds have good fungicidal activity.
    权利要求:
    Claims (2)
    [1]
    1. The UK patent K 1185039, cl. C 2 C, pub. 1970.
    [2]
    2. The UK patent number 118258, cl. C 2 C, pub. 1970 (prototype).
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    同族专利:
    公开号 | 公开日
    BE788973A|1973-03-19|
    DE2246645A1|1973-03-29|
    AU4615272A|1974-03-07|
    CH575711A5|1976-05-31|
    FR2154208A5|1973-05-04|
    NL7212841A|1973-03-27|
    KE2609A|1976-03-26|
    DE2265028C3|1978-06-08|
    DE2265029A1|1976-01-15|
    CA1039724A|1978-10-03|
    DE2265312A1|1977-06-16|
    DE2265029C3|1979-12-20|
    ATA243474A|1975-11-15|
    AU460810B2|1975-05-08|
    IL40271D0|1972-11-28|
    JPS5325009B2|1978-07-24|
    PL79502B1|1975-06-30|
    AT331562B|1976-08-25|
    DE2265312B2|1979-05-31|
    CS172959B2|1977-01-28|
    ES406966A1|1975-09-16|
    DE2265029B2|1979-04-12|
    DE2265028B2|1977-10-20|
    HK23576A|1976-04-30|
    NL160826C|1979-12-17|
    JPS4839640A|1973-06-11|
    AT334134B|1976-12-27|
    DD102058A5|1973-12-05|
    IT983165B|1974-10-31|
    DE2265028A1|1975-11-06|
    MY7600125A|1976-12-31|
    ZA725890B|1973-07-25|
    IL40271A|1977-05-31|
    GB1400710A|1975-07-23|
    HU165399B|1974-08-28|
    CY847A|1976-09-10|
    DE2246645B2|1977-07-07|
    DE2265312C3|1980-02-07|
    AT325051B|1975-10-10|
    US3880852A|1975-04-29|
    ATA243574A|1976-04-15|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    GB1181657A|1966-03-31|1970-02-18|Ici Ltd|Pyrimidine Derivatives and Compositions Containing them|
    GB1275312A|1969-05-28|1972-05-24|Ici Ltd|2-formamido-4-hydroxy pyrimidines and pesticidal compositions containing them|US4029784A|1971-09-23|1977-06-14|Imperial Chemical Industries Limited|Pyrimidine sulfamate fungicides|
    US3966732A|1972-02-19|1976-06-29|Schering Aktiengesellschaft|Nitroimidazolyl pyrimidines|
    US4620002A|1982-08-11|1986-10-28|Eastman Kodak Company|2-pyrimidyl alkanesulfonates|
    EP1941799A3|2004-12-17|2008-09-17|Devgen NV|Nematicidal compositions|
    CN101307024B|2008-07-16|2012-08-22|西安近代化学研究所|Method for synthesizing 5-nbutyl-2-ethylamido-6-methylpyrimidine-4-dimethyl amine sulfonic acid ester|
    CN105028420A|2015-08-17|2015-11-11|陕西上格之路生物科学有限公司|Sterilization composition containing spiroxamine and bupirimate|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    GB4440171A|GB1400710A|1971-09-23|1971-09-23|Pyrimidine sulphamates their preparation and use|
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