• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The compounds of formula: <IMAGE> are prepared from corresponding carboxylic acids of formula: <IMAGE> by a reaction capable of converting the carboxyl group to a functional derivative. The meaning of the symbols is given in Claim 1. Of the compounds obtained, those which have a 15-tetrahydropyranyloxy group can be hydrolysed, those which have a hydroxyl group can be esterified, and those which have a secondary alcohol group in position 15 can be oxidised to the corresponding ketone or dehydrated in position 15, 16; finally, the double bond in position 13, 14 and the triple bond of an alkynyl group in position 15 can be hydrogenated. The compounds display a hypotensive activity; they can be employed in the treatment of hypertension (high blood pressure) and of circulatory disorders.
    公开号:SU745366A3
    申请号:SU782623757
    申请日:1978-06-08
    公开日:1980-06-30
    发明作者:Бюандиа Жан；Вива Мишель
    申请人:Руссель-Юклаф (Фирма)；
    IPC主号:
    专利说明:

    of a product that is xromatographed on silica gel with a mixture of cyclohexane ethyl acetate (75/25. Obtain 160 mg of the desired product.
    权利要求:
    Claims (1)
    [1]
    1. R.Grewe, A.Helkke, C.Soiraner. Preparation and structure of some 3,4-d substituted cyclohexanecarboxylic acids. Chem. Her., 89, 1978 (1956).
    类似技术:
    公开号 | 公开日 | 专利标题
    SU745366A3|1980-06-30|Method of preparing cyclopentane carboxylic acid lactone
    US3725548A|1973-04-03|Substituted indenyl acetic acids in the treatment of pain, fever or inflammation
    IE781103L|1978-12-03|Ascorbic acid preparation and intermediates thereof
    GB799269A|1958-08-06|Production of intermediates for the synthesis of reserpine and related compounds
    SE7705637L|1977-05-13|PROCEDURE FOR THE PREPARATION OF DIBENSOXEPIN DERIVATIVES WITH THERAPEUTIC EFFECT
    US3932498A|1976-01-13|3-Indenyl-γ-|-acid compounds
    Lucas et al.1941|The Reduction of Tartaric Acid1
    Su et al.1960|Synthesis of Bromo-substituted Indoxyl Esters for Cytochemical Demonstration of Enzyme Activity1
    GB1424416A|1976-02-11|Prostaglandin intermediates and their preparation
    SU685152A3|1979-09-05|Method of synthesis of gamma-butyrolactone
    IE34314L|1970-12-18|Dibenzodioxocine derivatives
    CA2065433A1|1991-03-26|Synthesis of aryl alkanediols having high optical purity
    GB1395666A|1975-05-29|Thiophene derivatives processes for their preparation and compositions incorporating them
    IE46290L|1978-06-30|Improved method of preparing carboxylic acid esters
    IE38659L|1974-06-22|Pregnane acid derivatives.
    SU1164232A1|1985-06-30|Method of obtaining 2-acetylaminobenzimidazole
    Sumi et al.1958|The Stereochemical Correlation of |-α-Santonin, Artemisin and ψ-Santonin
    IE32928L|1969-06-14|Amino bicyclo carboxylic acids
    ES477208A1|1979-10-16|Process for producing aromatic aldehydes
    GB1515614A|1978-06-28|Preparation of m-benzoylhydratropic acid and an intermediate therefor
    GB1293870A|1972-10-25|Preparation of cis-1-alkenyl phosphonic acids and their o-carboxyphenyl esters
    IE44886L|1977-08-27|Quinoline carboxylic acid esters
    GB1205159A|1970-09-16|Process for the production of lactones
    SU545637A1|1977-02-05|-Carbethoxy-phenylhydrazides dialkyl- or diarylglycolic acids, showing analgesic activity
    GB1382852A|1975-02-05|Lactones
    同族专利:
    公开号 | 公开日
    JPS62146B2|1987-01-06|
    SE7702908L|1977-09-20|
    IE45124L|1977-09-19|
    ATA195077A|1979-11-15|
    IE45124B1|1982-06-30|
    JPS52113956A|1977-09-24|
    FR2344285B1|1979-02-02|
    SU749364A3|1980-07-15|
    DK119377A|1977-09-20|
    AU506760B2|1980-01-24|
    IL51690A|1982-02-28|
    LU76976A1|1977-10-03|
    AU2346677A|1978-09-28|
    GB1538717A|1979-01-24|
    DE2711950A1|1977-09-29|
    ZA771654B|1978-04-26|
    PT66326A|1977-04-01|
    AT357275B|1980-06-25|
    IL51690D0|1977-05-31|
    CA1094569A|1981-01-27|
    NL7703056A|1977-09-21|
    CH620688A5|1980-12-15|
    FR2344285A1|1977-10-14|
    HU178332B|1982-04-28|
    PT66326B|1979-01-18|
    BE852624A|1977-09-19|
    ES456999A1|1978-01-16|
    SE436877B|1985-01-28|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    FR2439779B2|1976-03-19|1981-05-22|Roussel Uclaf|
    FR2443466B1|1978-12-05|1982-03-19|Roussel Uclaf|
    DE3722133A1|1987-07-04|1989-01-12|Bayer Ag|AZOLYL TETRAHYDROPYRAN DERIVATIVES|
    EP1142886A1|2000-04-07|2001-10-10|Aventis Pharma Deutschland GmbH|Percyquinnin, a process for its production and its use as a pharmaceutical|
    CN100417650C|2006-08-17|2008-09-10|中国科学院昆明植物研究所|Vibralactone, preparation method and medicinal application thereof|
    CN102498105B|2009-07-28|2014-04-02|小野药品工业株式会社|Bicyclic compound and use thereof for medical purposes|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    FR7608004A|FR2344285B1|1976-03-19|1976-03-19|
    [返回顶部]