• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    Admixtures of a) an antifungal, antibacterial agent, such as povidone-iodine, (many others listed), b) a sugar e.g. sucrose and c) suitable carrier are substantially non-allergenic and have excellent healing properties when applied to burns or open wounds and serve as an effective barrier to the growth of healing tissue into gauze or similar dressing.
    公开号:SU1709895A3
    申请号:SU802909300
    申请日:1980-04-17
    公开日:1992-01-30
    发明作者:Альберт Кнутсон Ричард
    申请人:Richard Albert Knutson；
    IPC主号:
    专利说明:

    cl
    with
    is frustrated. Healing was observed after b days.
    Example 2: As in example 1, only 10 g of a complex of polyvinylpyrrolidone with iodine is mixed with 234 g of carrier (45.23 g of polyethylene glycol Mm 4000, 111.1 g of polyethylene glycol with Mm 400, 76.8 g of distilled water, 0.55 g of phosphate sodium and 0.25 g of ethoxylated octylphenol), then mixed with 756 g of a mixture of sugars (656 g of sugar and 100 g of bee honey). A composition is obtained in which the ratio of the complex polyvinylpyrrolidone-iodine: sugar 1:75, 6 and the carrier is 23.4% by weight of the composition,
    The composition was used to treat a wound on the left knee of a 22 year old woman. The composition was applied to gauze 5x5 cm and fixed with a bandage. Change of care 2 times a day, without serious consequences, the dressing did not stick to the wound. After 5 days, the wound healed almost completely.
    PRI me R 3. 70.82 g of a complex of polyvinylpyrrolidone with iodine are mixed sequentially with 234 g of carrier as in Example 2 and 708.22 g of sugar.
    The resulting composition contains 23.1% of the carrier, and the ratio of polyvinylpyrrolidone to iodine: sugar is 1:10.
    The composition was used to treat a wound on the elbow of a 13 year old girl. A gauze was applied onto the 5x5 cm gauze and fixed to the wound with a bandage. Change of setting 1 time per day, painless. The bag did not stick to the wound. After 3 days, complete wound healing was established.
    PRI me R 4. As in example 3, only a complex of polyvinylpyrrolidone with iodine and sugar is taken in the ratio of 1; 50 (15.02 g of the complex and 751 g of sugars) 335 g of glucose and 376
    g of fructose, the content of the carrier is 23.4% by weight of the composition,
    PRI me R 5. As in Example 3, only the complex of polyvinylpyrrolidone with iodine and sugar is taken in a ratio of 1:80 (9.45 g of the complex and 756 g of sugar). The content of the carrier at this time is 23.4% by weight of the composition.
    The amount of adhesion of the composition obtained in accordance with the invention in comparison with similar compositions, but without the addition of sugars, was determined by a known method.
    The adhesion of sugar-free compositions was almost the same, and its value was taken as 1.
    The adhesion value of the compositions according to examples 1-5 was 0.2; 0.1; 0.1; 0.1; 0.1 relative units.
    Thus, the proposed compositions allow a reduction in adhesion to the wound surface 5-10 times.
    权利要求:
    Claims (3)
    [1]
    1. A method of making an antimicrobial composition in the form of an ointment for application to a wound by mixing an antimicrobial agent with an antibacterial and antifungal actinvity carrier, characterized in that, in order to improve atraumatic properties, the composition is further mixed with sugars at a mass ratio of 1: (10-80) , and the carrier is used in an amount of 10-35% by weight of the composition.
    [2]
    2. A method according to claim 1, characterized in that a complex of polyvinylpyrrolidone with iodine is used as an antimicrobial agent.
    [3]
    3. The method according to claim 1, characterized in that sucrose, dextrose, fructose, honey, molasses, or a mixture thereof is used as sugars.
    类似技术:
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    同族专利:
    公开号 | 公开日
    DE3014524A1|1980-10-30|
    IL59881D0|1980-06-30|
    CA1125650A|1982-06-15|
    GB2048070A|1980-12-10|
    AU5739880A|1980-10-23|
    FR2454303B1|1984-12-28|
    AT386744B|1988-10-10|
    LU82364A1|1981-12-02|
    IL59881A|1983-12-30|
    CH653892A5|1986-01-31|
    ES490654A0|1981-03-16|
    JPS55141409A|1980-11-05|
    MX6178E|1984-12-05|
    AU536885B2|1984-05-31|
    ES8103551A1|1981-03-16|
    GB2048070B|1983-09-01|
    IT8012515D0|1980-04-18|
    SE451178B|1987-09-14|
    SE8002847L|1980-10-19|
    FR2454303A1|1980-11-14|
    NO801112L|1980-10-20|
    IT1136180B|1986-08-27|
    EG14319A|1983-12-31|
    JPH0617299B2|1994-03-09|
    ATA210680A|1988-03-15|
    BE882829A|1980-08-18|
    IN152625B|1984-02-25|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US434727A|1890-08-19|Lotion |
    US1611962A|1926-04-06|1926-12-28|Mats H Tolonen|Lotion|
    GB294734A|1927-05-23|1928-08-02|William Evans|A preparation for the cure of foot-rot in sheep, and for external application in other animal diseases|
    GB553564A|1941-08-25|1943-05-27|Charles Rudolph Hans Ritter|Iodization of textile fabrics|
    GB673578A|1949-08-18|1952-06-11|Upjohn Co|Dry ointment composition|
    US3859436A|1968-10-02|1975-01-07|Kolmar Laboratories|Sugar composition for topical application|
    US3767784A|1970-12-01|1973-10-23|S Gluck|Composition for the protection and treatment of injured body tissue and method of utilizing the same|
    US3944506A|1973-08-17|1976-03-16|Barnes-Hind Pharmaceuticals, Inc.|Abradant skin cleanser containing a borate salt|
    JPS5843404B2|1974-05-20|1983-09-27|Enu Shirubetsutei Ansooni|NZ199071A|1980-12-08|1984-05-31|Johnson & Johnson Prod Inc|Surgical dressing activated charcoal impregnated with anti-microbial agent|
    US4518517A|1983-03-16|1985-05-21|Colgate-Palmolive Company|Non-antimicrobial deodorant cleansing composition|
    JPS6198260A|1984-10-19|1986-05-16|Japan Res Dev Corp|Wound treatment material|
    NL8500774A|1985-03-18|1986-10-16|Dagra Nv|PROCESS FOR THE PREPARATION OF A FREE-LIQUID, HOMOGENEOUS POVIDONIC JEWEL POWDER.|
    DE3525440A1|1985-07-17|1987-01-22|Thiele Dr Ing Henry|AGENTS FOR THE TREATMENT OF POINTED, FIRE AND OTHER Wounds|
    GB8520664D0|1985-08-17|1985-09-25|Euro Celtique Sa|Suppository|
    AT78166T|1985-10-22|1992-08-15|Silvetti Anthony N|MONOSACCHARIDE CONTAINING COMPOSITION FOR HEALING Wounds.|
    JPH0132210B2|1986-03-12|1989-06-29|Kowa Kk|
    GB8622012D0|1986-09-12|1986-10-22|Euro Celtique Sa|Solid iodophor composition|
    EP0292551A1|1986-12-08|1988-11-30|Arseco, Inc.|A storage stable topical composition|
    US4847078A|1987-01-14|1989-07-11|Arseco, Inc.|Storage stable topical composition having moisture control agent|
    JPH01132515A|1987-11-18|1989-05-25|Kowa Co|Germicidal composition for external use|
    US5034421A|1988-12-13|1991-07-23|Fuisz Pharmaceutical Ltd.|Moderated spun fibrous system and method of manufacture|
    JPH0377828A|1989-08-21|1991-04-03|Tanabe Seiyaku Co Ltd|Iodophor composition for preventing mammititis|
    JPH03167123A|1989-11-24|1991-07-19|Tsutomu Ishibashi|Drug for bed sore|
    GB9102660D0|1991-02-07|1991-03-27|Ultra Lab Ltd|Wound dressing materials|
    JP3583166B2|1994-06-27|2004-10-27|興和株式会社|Powder preparation for damaged skin repair|
    DE19957918A1|1999-11-25|2001-06-13|Ulrich Doht|Disinfectant cleaner for cleaning and care and process for its manufacture|
    USRE42755E1|1999-12-09|2011-09-27|Apimed Medical Honey Limited|Honey based wound dressing|
    JP4841733B2|2001-01-31|2011-12-21|三笠製薬株式会社|Wound treatment formulation|
    DE102013018941A1|2013-11-12|2015-05-13|Tosama Sanitetnega Materiala D.O.O.|Fluid for wound treatment and wound dressing|
    EP3160454A1|2014-06-26|2017-05-03|Tenerelli, Simone|Improved pharmaceutical composition for the protection and healing of pressure ulcers, diabetic ulcers and vascular ulcers|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    US3116279A| true| 1979-04-18|1979-04-18|
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