• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    An indoloquinoline system compound represented by the following formula (1): A benzo(b)acridine system compound represented by the following formula (2): A benzo(c)acridine system compound represented by the following formula (3): Processes for preparing the above compounds and carcinostatic composition containing at least one of the above compounds.
    公开号:SU1706390A3
    申请号:SU894613720
    申请日:1989-03-09
    公开日:1992-01-15
    发明作者:Ямато Масатоси
    申请人:Мект Корпорейшн (Фирма)；
    IPC主号:
    专利说明:

    The concentration of the compound capable of causing 50% growth inhibition (ED50) compared with the control is determined. The compound is considered effective at less than L μg / ml.
    The test results for the cancer-static effect are given in Table 1.
    1 In Table 3, comparisons of known compounds are given.
    权利要求:
    Claims (1)
    [1]

    EN50 2 CH 3
    available in that the indolo (3,2-b) -Y-chloroquinoline of the formula

    40 is reacted with 2-methoxy-4-methylsulfamidoplaniline of the formula
    εΗ 3 50 2 ΝΗ- <δ -ΝΗ 2 main 3
    in the presence of concentrated hydrochloric acid.
    类似技术:
    公开号 | 公开日 | 专利标题
    SU1706390A3|1992-01-15|Method for preparation n-/| chinoline - 10-yl)amino]-3-methoxyphenyl) amide hydrochloride
    JPH01207288A|1989-08-21|Indole derivative
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    JPS63211266A|1988-09-02|Intermediate for dihydropyridine derivative
    JPH0348648A|1991-03-01|Pharmaceutical acting as anti-arteriosclerotic and novel di-t-butyl hydroxyphenyl derivative
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    MY104829A|1994-06-30|3-phenyl-5, 6-dihydrobenz [c]acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents.
    JPH02152963A|1990-06-12|4-phenyl-4-| amido) piperidine derivative and pharmaceutical composition containing the same
    JPH02300184A|1990-12-12|Indole derivative
    KR930006003A|1993-04-20|Imidazolylmethyl-pyridine compounds
    JPH02138263A|1990-05-28|Imidazole derivative, production thereof and anti-ulcer agent containing the same derivative
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    JPS574977A|1982-01-11|2-guanidinothiazole derivative
    JPH02134320A|1990-05-23|Pharmaceutical composition
    EP0666263A4|1995-09-06|
    JPH04198160A|1992-07-17|New carbodiimide derivative and its production
    KR890003725A|1989-04-17|Amine derivatives and salts thereof, preparation methods thereof and ulcers containing the same
    JPS6422898A|1989-01-25|2-alanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivative
    JPS5233640A|1977-03-14|Process for preparation of benzenedicarboxylic acid amides
    同族专利:
    公开号 | 公开日
    DK116289A|1989-09-11|
    IL89510A|1992-08-18|
    NO167861B|1991-09-09|
    FI891061A0|1989-03-06|
    JPH01228965A|1989-09-12|
    BR8901100A|1989-10-31|
    AU3112089A|1989-09-14|
    AU618991B2|1992-01-16|
    IL89510D0|1989-09-10|
    FI891061A|1989-09-11|
    HUT50818A|1990-03-28|
    NO891024D0|1989-03-09|
    US5128345A|1992-07-07|
    EP0332190A2|1989-09-13|
    NZ228275A|1990-12-21|
    ZA891758B|1989-11-29|
    KR890014536A|1989-10-24|
    NO167861C|1991-12-18|
    EP0332190A3|1991-04-24|
    CN1036763A|1989-11-01|
    DK116289D0|1989-03-10|
    HU203225B|1991-06-28|
    NO891024L|1989-09-11|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    JPS63101369A|1986-10-17|1988-05-06|Mect Corp|Indenoquinoline compound, production thereof and anti-cancer drug comprising said compound as active ingredient|
    JPH02256667A|1988-12-27|1990-10-17|Masatoshi Yamato|Condensed quinoline-based compound and production thereof|JPH02256667A|1988-12-27|1990-10-17|Masatoshi Yamato|Condensed quinoline-based compound and production thereof|
    WO2005054236A1|2003-11-20|2005-06-16|Crystax Pharmaceuticals S.L.|Substituted quinolines for the treatment of cancer|
    CN103497211B|2013-10-15|2016-07-20|中国海洋大学|Indoloquinoline derivant and its preparation method and application|
    CN103614134B|2013-11-08|2014-11-05|吉林奥来德光电材料股份有限公司|Organic electroluminescent material and preparation method thereof|
    CN104860945B|2014-02-25|2016-08-24|北京大学|Condense acridine derivatives and pharmaceutical composition, preparation method and application|
    CN103951694A|2014-04-14|2014-07-30|上海大学|Acridine or benzacridine derivative and synthesis method thereof|
    CN105669551B|2015-12-02|2018-04-17|广西中医药大学|7 benzoacridines are to fluorobenzoyl amido thiocarbamide and its preparation method and application|
    CN105418501B|2015-12-02|2018-04-17|广西中医药大学|7 pairs of anisidino- benzo [c] acridine hydrochlorides and its preparation method and application|
    CN105481769B|2015-12-02|2018-07-10|广西中医药大学|A kind of benzoacridine derivatives and its preparation method and application|
    CN105399671B|2015-12-02|2018-04-17|广西中医药大学|7 p-totuidine base benzo [c] acridine hydrochlorides and its preparation method and application|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    JP63056883A|JPH01228965A|1988-03-10|1988-03-10|Condensed quinoline and condensed acridine, their production and anticancer agent containing said compounds|
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