• 专利附录
  • 专利说明
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  • 类似技术
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    • 专利摘要:
    The present invention relates to cosmetic cleansers containing biotensioactives and having prebiotic activity. Prebiotic activity is achieved by combining biosurfactants with anionic surfactants. The cosmetic cleanser of the invention also has excellent foaming and washing properties. The present invention further relates to the use of biotensioactives as ingredients having prebiotic activity in cosmetic cleansers.
    公开号:FR3040874A1
    申请号:FR1658398
    申请日:2016-09-09
    公开日:2017-03-17
    发明作者:Heike Schelges；Maria Tretyakova；Brigitte Ludwig
    申请人:Henkel AG and Co KGaA；
    IPC主号:
    专利说明:

    The present invention relates to cosmetic cleansers containing biotensioactives and having prebiotic activity. Prebiotic activity is achieved by combining biosurfactants with anionic surfactants. The cosmetic cleanser of the invention also has excellent foaming and washing properties.
    Skin inflammation states are caused by harmful bacteria, such as Propionibacterium acnes, which are permanently on the skin, but which multiply more strongly under certain conditions and thus lead, for example, to an 'impure skin Or acne. It is therefore essentially microorganisms (bacteria and fungi) that are classified as pathogens.
    However, the resident bacterial flora of the skin is also composed of other bacterial species which not only do not harm, but rather oppose their growth to harmful germs and therefore have an important protective function. These species include, in particular, coagulase-negative staphylococci such as S. epidermidis.
    Non-selective antibacterial agents, such as those used for example to prevent and fight acne in the usual commercial cosmetics, eliminate not only unwanted cutaneous germs but also the desired skin germs and thus cause a disturbance of the biological balance, which can have different undesirable consequences. In addition, certain other ingredients of cosmetic cleaners such as surfactant mixtures may contribute in certain circumstances to such disruption.
    There is therefore a need for means which selectively favor, at the application site on the skin, the growth and / or the survival capacity of the desired seeds of the flora of the skin with respect to the growth and / or the ability to survive unwanted germs from the flora of the skin. Such substances are also referred to as "prebiotics".
    DE 10 2004 011968 A1 discloses plant extracts, in particular coniferous extracts, having prebiotic activity on the skin.
    In addition, durability in the use of cosmetic ingredients is gaining importance and is increasingly being sought by consumers and manufacturers of cosmetic cleaning agents.
    Biotensiatives are surface active substances of microbial origin that can be prepared from vegetable oil or sugar substrates. These substrates may consist in part of agricultural waste such as rice husks or waste water from the sugar industry so that in this case also no raw materials of food production are lost. Biotensioactives meet the requirements of sustainability because they are made from renewable raw materials. They are used both in household cleaners, laundry detergents and dishwashing detergents (eg US 5,520,839, DE 19600743 A1), as well as in various cosmetic cleansing agents (for example, WO 2014/095367 A1). , WO 2013/098066 A2).
    However, they generally have a lower foaming power, for example that of anionic surfactants. WO 2013/098066 A2 discloses biosurfactants which are used in combination with other surfactants and fatty acids in cosmetic cleaners. However, fatty acids frequently alter the foaming power.
    An object of the present invention was to provide cosmetic cleaners having prebiotic activity and at the same time good washing properties, including good foaming power.
    Surprisingly, it has been discovered that cosmetic cleansers, which contain as surfactants biosurfactants in combination with anionic surfactant, have prebiotic activity. The ingredients contained in the cosmetic cleaners of the invention can satisfy a large part of the durability and biodegradability requirements.
    The present invention relates to: 1. a cosmetic cleanser having a prebiotic activity, characterized in that it contains one or more biosurfactants in combination with one or more anionic surfactants. 2. a cosmetic cleanser according to item 1 which contains, each time relative to the total weight of the cosmetic cleaning: (a) from 1 to 20% by weight of one or more biosurfactants and (b) from 1 to 10% by weight of one or more anionic surfactants. 3. a cosmetic cleanser according to item 1 or 2, which contains 1 to 10% by weight of the biosurfactant (a) and 3 to 10% by weight of the anionic surfactant (b). 4. a cosmetic cleanser according to one of the preceding points, which contains as biosensitive (a) a glycolipid, a lipopeptide or a combination thereof. 5. a cosmetic cleanser according to one of the preceding points, wherein the biosurfactant (a) is chosen from rhamnolipids, sophorolipids, mannosylerythritols, surfactins, fatty acyl glutamates, fatty acyl glycinates and their derivatives. combinations. 6. a cosmetic cleanser according to item 5, wherein the sophorolipid is a mixture of the acid form and the lactone form, 20 to 60% by weight being in the acid form. 7. a cosmetic cleanser according to item 5, wherein the rhamnolipid is a mixture of mono- and dirhamnolipid which are each derived from 3-hydroxydodecanoic acid and / or 3-hydroxyundecanoic acid. 8. a cosmetic cleanser according to one of the preceding points, wherein the anionic surfactant (b) is chosen from linear alkyl sulphates having from 8 to 24 carbon atoms, their ethylene oxide adducts. and their combinations. 9. a cosmetic cleanser according to one of the preceding points, wherein the anionic surfactant (b) is an alkyl ether-sulfate having 10 to 18 carbon atoms, preferably 12 to 14 carbon atoms, and 1 to 6 ethylene oxide units, preferably a lauryl ether sulfate having 2 to 4 ethylene oxide units. 10. a cosmetic cleanser according to one of the preceding points, which further contains one or more cosmetically acceptable preservatives in a total amount of 0.05 to 1% by weight or e 0.1 to 1% by weight or 0, 2 to 0.7% by weight, based on the total weight of the cosmetic cleanser. 11. a cosmetic cleanser according to one of the preceding points, wherein the cosmetic cleanser contains 0.5% by weight, or less, of free fatty acid, preferably none. 12. a cosmetic cleanser according to one of the preceding points, which is formulated as a body cleanser, or facial cleansers or cleanser for the cosmetic treatment of acne. 13. Cosmetic use of a cleanser according to one of the preceding points for the treatment of acne. 14. Use of biotensioactives as a component with prebiotic activity of cosmetic cleanser having prebiotic activity on the skin. 15. Use of biosurfactants in combination with anionic surfactants as prebiotically active ingredients of cosmetic cleansers having prebiotic activity on the skin.
    By prebiotic activity is meant according to the invention the fact that the growth and / or the survival capacity of the seeds or microflora which are desired, in particular which are not irritating to the skin, is favored with respect to the growth and / or the ability to survive germs or microflora that are undesirable, especially those that are harmful to the skin. This object is achieved according to the invention in particular by the fact that the cosmetic cleanser, which contains a biosurfactant and anionic surfactant, inhibit on the one hand the growth of unwanted germs of the skin and on the other hand has no direct influence on the growth of the desired skin germs or promotes the growth of desirable skin germs.
    According to the invention, the term "skin" preferably designates the skin itself, and in particular the human skin, but also the mucosa and the integuments, insofar as they contain living cells, in particular follicles. hair, the hair bulb, the ventral epithelium of the nail bed (Lectulus) and the sebaceous glands and sweat glands.
    The desired skin sprouts are preferably benign and / or non-pathogenic and / or non-irritating skin and / or coagulase negative staphylococci, in particular S. epidermidis, S. hominis, S. warneri, S. saprophyticus , S. xylosus, S. capitis or S. simulans, preferably S. epidermidis and / or S. wameri.
    Undesirable cutaneous germs, the growth of which is inhibited, are in particular Propionibacterium acnes.
    Preferably, the cosmetic cleanser of the invention, having a prebiotic activity on the skin, is suitable for reproducing and stabilizing the natural healthy microbial balance of skin flora. The subject of the present invention also relates to the use of biosurfactants, preferably in combination with anionic surfactants, as a prebiotically active ingredient of cosmetic cleansers having prebiotic activity on the skin. The use is aimed in particular at inhibiting the growth of undesirable skin germs and at the same time not influencing or even promoting the growth of the desired skin germs.
    The preferred embodiments and ingredients relating to the cosmetic cleanser of the invention are applicable mutatis mutandis to the preferred uses.
    The present invention also relates to the non-therapeutic cosmetic use of cleaners of the invention for the treatment of acne.
    The cosmetic cleanser of the invention contains as essential ingredient one or more biosurfactants.
    By biotensioactives are meant substances which are produced by microorganisms and which are often also removed from the cell. Biotensioactives are like conventional surfactants surface active substances that reduce the surface tension of liquids and thus promote the mixing of aqueous phases (hydrophilic) and hydrophobic (hydrophobic). Bio-based surfactants can be manufactured under mild production conditions that require low energy consumption. They are generally easily biodegradable and is very low pollutant. They are also non-toxic and their production is also done without toxic byproducts. The raw materials used for their microbial production are carbohydrates, in particular sugars such as glucose and / or lipophilic carbon sources such as fats, oils, partial glycerides, fatty acids, fatty alcohols, hydrocarbons saturated or unsaturated long chain. According to the invention, the biotensioactives are preferably biotensioactives produced by fermentation.
    Biotensiatives include glycolipids, lipopeptides, lipoproteins, fatty acids, phospholipids, neutral lipids and polymeric surfactants (eg emulsan) which can all also be used in the present invention.
    The glycolipids that can be used in the present invention are compounds in which one or more monosaccharide units are connected to a lipid moiety by a glucosidic linkage. Examples of glycolipids used as biosurfactants according to the invention are the rhamnolipids, the sophorolipids, the lipids of mannosylerythritol and the lipids of trehalose. Among them, rhamnolipids, sophorolipids, mannosylerythrol lipids and combinations thereof are preferred.
    Rhamnolipids are obtained from bacteria of the genus Pseudomonas, in particular Pseudomonas aeruginosa, preferably during growth on hydrophobic substrates such as n-alkanes or vegetable oils. Other glycolipids, for example glucose lipids, cellobiose lipids or trehalose lipids, are produced by yet other microorganisms on various substrates. In addition, according to the invention, mannosylerythritol lipids are preferred glycolipidic biotensives; they are produced by bacteria of the genera Pseudozyma, Candida antarctica and Ustilago.
    According to the invention, rhamnolipids have the following general formula:
    in which m is equal to 2, 1 or 0, n is 1 or 0, R 1 and R 2 are independently identical or different organic radicals having 2 to 24, preferably 5 to 13, carbon atoms, in particular an alkyl radical; substituted or unsubstituted, branched or unbranched, which may also be unsaturated, the alkyl radical being preferably a linear saturated alkyl radical having 8 to 12 carbon atoms, more preferably a nonyl or decyl radical, or a mixture thereof .
    The salts of these compounds are also included in the present invention.
    The term "di-rhamnolipid" in the present invention refers to compounds of the above formula or their salts wherein n is 1.
    Therefore, the term "mono-rhamnolipid" in the present invention refers to compounds of the general formula or their salts wherein n is 0.
    According to the invention, mixtures of mono- and dirhamnolipids are preferably used. The monorhamnolipid to dirhamnolipid ratio is preferably from about 2: 1 to 4: 1, more preferably from 2.5: 1 to 3: 1. Particularly preferred mixtures of mono- and dirhamnolipids are wherein, in the above formula, R1 and R2 are independently nonyl radical or linear decyl radical. In the latter case, it is therefore rhamnolipids which are each derived from 3-hydroxydodecanoic acid and / or 3-hydroxyundecanoic acid. Such mixtures are commercially available, for example as rhamnolipid R90, R95 or R98 from Agae Technologies, U.S.A., the number indicating in each case the degree of purity. According to the invention, rhamnolipid R90 can be used in a particularly preferred manner.
    The sophorolipids are produced by fermentation with yeasts such as Candida bombicola (also known as Torulopsis bombicola), Yarrowia lipolytica, Candida apicola (Torulopsis apicola) and Candida bogoriensis by growth on sugars, hydrocarbon substances, vegetable oils or mixtures thereof
    The sophorolipids have the formulas (1) indicated below (lactone form) and (2) (free acid), both forms being generally present in the mixture.
    O)
    (2) in which R1 and R1 'are independently saturated hydrocarbon chains or monounsaturated or polyunsaturated hydrocarbon chains, in particular monounsaturated, having from 8 to 20, in particular from 12 to 18, carbon atoms, more preferably from 14 to 18 carbon atoms, which may be linear or branched and which may comprise one or more hydroxyl groups, R2 and R2 'independently represent a hydrogen atom or a saturated alkyl radical or a monounsaturated or polyunsaturated alkyl radical, in particular monounsaturated, having from 1 to 9 carbon atoms, preferably 1 to 4 carbon atoms, which may be linear or branched, and which may comprise one or more hydroxyl groups, and R3, R3 ', R4 and R4' independently represent an atom of hydrogen or an acetyl group.
    The preferred sophorolipids are those in which R1 and R1 'are a monounsaturated linear hydrocarbon chain having 15 carbon atoms. It is further preferred that R2 and R2 'are a methyl group or a hydrogen atom, preferably each a methyl group.
    According to the invention, the preferred sophorolipids are those in which the acid form and the lactone form are present in the mixture, preferably about 20% to about 60% by weight of the sophorolipid are present in the acid form and the rest of the sophorolipid is present in the lactone form.
    In particular, the preferred sophorolipids are those in which the compounds of the formulas above (1) and (2) are present in a mixture, R1 and R1 'representing a monounsaturated linear hydrocarbon chain having 14 to 18 carbon atoms, preferably 15 carbon atoms, R3 and R4 representing an acetyl group, R3 'and R4' representing a hydrogen atom and R2 and R2, representing a methyl group, and approximately 20% to 60% by weight of sophorolipids in the form of acid.
    These sophorolipids are commercially available, for example under the name Sopholiance S from Soliance. More specifically, the sophorolipid available under the trade name Sopholiance S from SOLIANCE is a solution of sophorolipid at 60% by weight and is obtained, for example, by fermentation of Candida bombicola on rapeseed oil methyl ester. and glucose (INCI: Candida bombicola / glucose / methyl rapeseed ferment (and) water). Sopholiance S is a preferred sophorolipid according to the invention.
    Soliance S contains the free acid form at about 20% by weight, in admixture with the lactone form.
    The lipids of mannosylerythritol are glycolipids of the following general formula:
    in which the R 1 independently represent fatty acid acyl groups having 4 to 24 carbon atoms, preferably 8 to 12 carbon atoms, the R 2 independently represent a hydrogen atom or an acetyl group and R 3 represents an atom of hydrogen or an acyl group of fatty acid having 2 to 24 carbon atoms. A suitable mannosyerythritol lipid according to the invention is commercially available under the name Ceramela-B (Toyobo) (INCI: Pseudozyma Tsukubaensis / Olive Oil / Glycerin / Soy Protein Ferment).
    The bio-surfactants also include the group of substances of lipids and lipid derivatives which include lipopeptides in particular. In general, the lipopeptides are synthesized non-ribosomally from the respective microorganisms, for example Gram-positive bacteria, in particular Bacillus and Streptomyces genera, Gram-negative bacteria, in particular of the genus Pseudomonas and myxobacteria, and filamentous fungi. Peptide chains generally consist of two to forty amino acids and can be linear, cyclic or branched. Unlike peptide chains synthesized ribosomally, they often include as monomeric components not only protein-forming L-amino acids, but also D-amino acids and carboxylic acids and / or alpha-hydroxy carboxylic acids of all kinds. . The amino acids are most often L-α- or Da-amino acids, however there may also be β-, γ- or δ-amino acids which may also be present in D or L configuration. The peptide chains may also include other chemical modifications, in particular they may be glycosylated, hydrolysed, N-methylated or N-formylated. The common structural elements are further thiazoline and / or oxazoline rings in different oxidation states. A known lipopeptide biosensitive is surfactin which has the following structure and which is generally used in the form of an alkaline or ammonium salt:
    An appropriate surfactin according to the invention is commercially available from Kaneka.
    Lipopeptides, which can be used as biotensioactives according to the invention, also comprise so-called fatty acyl glutamates. They have the following general formula:
    wherein R is a straight or branched alkyl chain having 5 to 21 carbon atoms, preferably 7 to 17 carbon atoms, more preferably 12 to 16 or 13 to 15 carbon atoms. Fatty acyl glutamates used as biosurfactants are usually in a mixture in which R has different chain lengths. The radical R may also be hydroxylated, preferably monohydroxylated; in this case, hydroxylation in the β position is preferred. Fatty acyl glutamates used as biosurfactants are available, for example, from Modular Genetics, Inc., USA.
    Lipopeptides, which can be used in a preferred manner according to the invention as biotensioactives, include so-called fatty acyl glycinates. They have the following general formula: RC (O) NHCH2CO2X, in which - R is a linear or branched alkyl chain having 5 to 21 carbon atoms, preferably 7 to 17 carbon atoms, preferably 12 to 16 or from 13 to 15 carbon atoms, and - X is a cation, preferably an alkali metal or ammonium cation, more preferably a sodium or ammonium cation, or -H.
    The fatty acyl glycinates used as biotensioactives may also be present in a mixture in which R may have different chain lengths.
    The fatty acyl glycinates used as biosurfactants are available for example from Modular Genetics, Inc., USA.
    According to the invention, the preferred cosmetic cleaners are those containing the following biotensioactives: rhamnolipids and / or sophorolipids such as glycolipids, surfactin, fatty acyl glutamates and / or fatty acyl glycinates such as lipopeptides, and combinations thereof.
    The cosmetic cleaner contains the biosurfactants preferably in an amount of about 0.5 to 50% by weight, preferably about 0.5 to 20% by weight, more preferably about 1 to 10% by weight, more preferably preferred from 1 to 5% by weight, based on the total weight of the cleaner. If they are mixtures of biotensioactives, the percentages refer to the total amount> of biosurfactants contained.
    The cosmetic composition of the invention contains as another essential component one or more anionic surfactants.
    Suitable anionic surfactants are in principle all surface active anionic substances suitable for use on the human body. They are characterized by a hydro-solubilizing anionic group such as a carboxylate, sulphate, sulphonate or phosphate group and a lipophilic alkyl group having about 8 to 30 carbon atoms. In addition, the molecule may contain glycol or polyglycol ether groups, ester, ether and amide groups and hydroxyl groups. Examples of suitable anionic surfactants are each in the form of sodium, potassium and ammonium salts and of mono-, di- and trialkanolammonium having from 2 to 4 carbon atoms in the alkanol, acid ether group. carboxylic acid of the formula R-O- (CH 2 CH 2 O) x -CH 2 -COOH, wherein R is a linear alkyl group having 8 to 30 carbon atoms and x = 0 or 1 to 16, the acylsarcosides having from 8 to 24 carbon atoms; carbon in the acyl group, acyltaurides having 8 to 24 carbon atoms in the acyl group, acylisethionates containing 8 to 24 carbon atoms in the acyl group, monoesters and dialkyl esters of sulfosuccinic acid having 8 to 24 atoms of carbon in the alkyl group and the monoalkyl polyoloxy esters of sulfosuccinic acid having 8 to 24 carbon atoms in the alkyl group and 1 to 6 oxyethyl groups, the linear alkanesulfonates having 8 to 24 carbon atoms, the alpha sulfonates olefin 8 to 24 carbon atoms, alphasulphonic fatty acid methyl esters having 8 to 30 carbon atoms, alkyl sulphates of the formula R-OSO 3 H, wherein R is a preferably linear alkyl group having 8 to 24 carbon atoms; at 30 carbon atoms, the alkylpolyglycol ethersulfates of the formula R-O (CH 2 CH 2 O) x -SO 3 OH, wherein R is a preferably linear alkyl group having 8 to 30 carbon atoms and x = 1 to 12, the mixtures of surface-active hydroxysulfonates, sulfated hydroxyalkylpolyethylene and / or hydroxyalkylenepropylene glycol ethers, unsaturated fatty acid sulfonates having 8 to 24 carbon atoms and 1 to 6 double bonds, esters such as tartaric acid and citric acid with alcohols, the adducts of about 2 to 15 molecules of ethylene oxide and / or propylene oxide to fatty alcohols having 8 to 22 carbon atoms, the ether-alkyl phosphates and / or alk enyl, sulphated fatty acid alkylene glycol esters of the formula RCO (Alko) nSO 3 M wherein RCO- represents a linear or branched, aliphatic, saturated and / or unsaturated acyl radical having from 6 to 22 carbon atoms, Alk represents CH 2 CH 2, CHCH 3 CH 2 and / or CH 2 CHCH 3, n represents numbers from 0.5 to 5 and M represents a cation, as described, amidethercarboxylic acids, condensation products of CC fatty alcohols containing hydrolysates of proteins and / or amino acids and their derivatives, which are known to those skilled in the art as albumin fatty acid condensates such as Lamepon® types, Gluadin® types, Hostapon®KCG types or Amisoft® types.
    Preferred anionic surfactants are selected from linear alkyl sulfates having 8 to 24 carbon atoms, their ethylene oxide adducts, and combinations thereof. The ethylene oxide adducts of linear alkyl sulfates (alkyl ether sulfate) are particularly preferred. More preferably, the anionic surfactant (b) is an alkyl ether-sulfate having 10 to 18 carbon atoms, preferably 12 to 14 carbon atoms, and 1 to 6 ethylene oxide units, more preferably 2 to 4 units of ethylene oxide, preferably a lauryl ether sulphate having from 2 to 4 ethylene oxide units, still more preferably sodium lauryl ether sulphate having 2 oxide groups; ethylene.
    The cosmetic cleanser of the invention contains the anionic surfactant preferably in an amount of about 0.5 to 30% by weight, preferably about 1 to 20% by weight, more preferably about 2 to 15% by weight. weight, more preferably 3 to 10% by weight, based on the total weight of the cleaner. If they are anionic surfactant mixtures, the percentages relate to the total amount of anionic surfactants.
    In preferred embodiments of the invention, the cosmetic cleanser contains, apart from the biosurfactant and the anionic surfactant, no other surfactant or at least not more than 0.5% by weight of another surfactant, preferably not more than 0.2% by weight, more preferably not more than 0.1% by weight of another surfactant. By another surfactant is meant here nonionic, cationic and amphoteric or zwitterionic surfactants.
    However, in other embodiments, there may be another surfactant, particularly a nonionic surfactant, but preferably in a small amount. An example of a nonionic component having a surfactant activity is PEG-7 glyceryl cocoate (INCI).
    The cosmetic cleanser of the present invention preferably contains 0.5% or less of free fatty acid, preferably none. A low fatty acid content has the advantage that the foaming power of the cosmetic cleanser is not impaired.
    The cosmetic cleanser of the present invention may contain preservatives commonly used in the cosmetic field. Preservatives used in cosmetics generally act as broadband preservatives, including on nonspecific germs. As mentioned in the introduction, they eliminate not only unwanted skin germs, but also the desired skin germs and disrupt the biological balance of the skin. In the present invention, surprisingly, there is prebiotic activity on the skin despite the presence of conventional preservatives. The preservatives contained are preferably organic acids or their salts such as phenoxyethanol, methylparaben, ethylparaben, sodium benzoate, sodium salicylate and combinations thereof. According to the invention, sodium benzoate, sodium salicylate or a combination thereof is preferably used as the preservative. Preferably, the cosmetic cleanser contains cosmetically acceptable preservatives in only small amounts, preferably in a total amount of 0.05 to 5% by weight or 0.1 to 3% by weight, 0.2 to 1%. by weight or from 0.2 to 0.7% by weight, relative to the total weight of the cosmetic cleanser. If there are several preservatives, the percentages relate to the total amount of preservatives.
    It has been found that in particular in a combination of biotensioactives, in particular rhamnolipid and / or lipopeptide, with an alkyl ether-sulphate, in particular lauryl ether-sulphate having from 2 to 4 ethylene oxide units such as anionic surfactant and sodium benzoate and / or sodium salicylate as a preservative, particularly good prebiotic activity of cosmetic cleaners has been obtained.
    According to the invention, the cosmetic support contained in the cosmetic cleanser is water. In embodiments of the invention, there may be other usual carriers, but given the biological biodegradability and natural availability of raw materials, it is preferred that the cosmetic cleanser of the invention contains water as support.
    The cosmetic cleanser may contain according to the invention other common ingredients cosmetic cleaners. Examples of these usual ingredients are odorants or perfumes, thickeners, opacifiers, preservatives, pH regulators such as citric acid, and / or skincare substances. However, the present invention is not limited to these additional ingredients.
    The preferred thickeners according to the invention are thickeners of plant origin such as polysaccharides, such as celluloses (cellulose itself and its derivatives), alginic acids (and their corresponding physiologically acceptable salts, alginates), agar-agar (with the agarose polysaccharide present as a main ingredient in the agar-agar), starch fractions and derivatives such as amylose, amylopectin and dextrins, karaya gum, gum gellan, locust bean gum, gum arabic, dextrans, guar gum and xanthan gum or combinations thereof.
    Suitable cellulose derivatives are methylcellulose, ethylcelluloses, hydroxyalkylcelluloses (eg hydroxyethylcellulose), methylhydroxyalkylcelluloses and carboxymethylcelluloses (INCI: cellulose gum) as well as their physiologically acceptable salts.
    The odorants or perfumes used are particularly preferably according to the invention the natural odorous substances. If an odorant substance is present, it is preferably in an amount of 0.05 to 2% by weight, preferably 0.1 to 1.5% by weight, preferably 0.2 to 1% by weight. by weight, and also preferably from 0.5 to 1% by weight, each time relative to the total weight of the cleaner. If several odorous substances are present, the percentages refer to the total quantity of odorants or perfumes.
    The cleanser may contain, as a care substance, for example oily substances, preferably natural oily substances such as vegetable oils, plant extracts, but also monosaccharides and polysaccharides and / or lipids. As an example, Aloe Vera extracts may be mentioned. Another suitable care substance is glycerine which also acts as a moisturizer.
    The cosmetic cleansers can be formulated according to the invention in the form of a body cleanser, a facial cleanser or a cleanser for the cosmetic treatment of acne, in the form of a shampoo, a shower gel, facial gel or other known cosmetic formulation forms.
    Summary table :
    In the following, it is presented the preferred cosmetic cleaners of the invention. The data are in percent by weight and relate to the concentration of active substance.
    By "various" is meant according to the invention essentially water, optionally in combination with another cosmetic medium, but preferably the cosmetic carrier but includes only water. "Other" may optionally refer to other usual ingredients of cosmetic cleansers such as preservatives, care substances, pH regulators, such as acids, and / or odorants.
    In preferred embodiments, "various" refers to free fatty acids and other surfactants, particularly cationic and amphoteric surfactants.
    Examples
    The following cosmetic cleansers shown in the table were prepared. The data are indicated in percentages by weight, each time relative to the total weight of the cleaner.
    Table 1
    For both compositions, excellent overall cosmetic performance was observed, including foaming power, washing behavior, and skin / hair sensation.
    It has also been found in in vitro tests that the cosmetic cleansers of Examples 1 and 2 inhibited the growth of Propionibacterium acne and promoted the growth of Staphylococcus epidermis.
    权利要求:
    Claims (10)
    [1" id="c-fr-0001]
    claims
    1. Cosmetic cleanser having a prebiotic activity, characterized in that it contains one or more biosurfactants in combination with one or more anionic surfactants.
    [2" id="c-fr-0002]
    2. Cosmetic cleanser according to claim 1, each containing, based on the total weight of the cosmetic cleaning: (a) from 1 to 20% by weight of biotensioactives and (b) from 1 to 10% by weight of one or more of anionic surfactants.
    [3" id="c-fr-0003]
    3. Cosmetic cleanser according to claim 1 or 2, which contains as biosurfactant (a) a glycolipid, a lipopeptide or a combination thereof.
    [4" id="c-fr-0004]
    4. Cosmetic cleanser according to one of the preceding claims, wherein the biotensioactif (a) is selected from rhamnolipids, sophorolipids, mannosyl erythritols, surfactins, fatty acyl glutamates, fatty acyl glycinates and combinations thereof.
    [5" id="c-fr-0005]
    5. Cosmetic cleanser according to one of the preceding claims, wherein the anionic surfactant (b) is selected from linear alkane sulfates having 8 to 24 carbon atoms, their ethylene oxide adducts, and their combinations.
    [6" id="c-fr-0006]
    A cosmetic cleanser according to any one of the preceding claims, which further contains one or more cosmetically acceptable preservatives in a total amount of 0.1 to 1% by weight, based on the total weight of the cosmetic cleanser.
    [7" id="c-fr-0007]
    7. Cosmetic cleanser according to one of the preceding claims, the cosmetic cleanser not containing free fatty acid.
    [8" id="c-fr-0008]
    8. Cosmetic cleanser according to one of the preceding claims, which is formulated in the form of a body cleanser, facial cleanser or a cleanser for the cosmetic treatment of acne.
    [9" id="c-fr-0009]
    9. Cosmetic use of a cleaner according to one of the preceding claims for the treatment of acne.
    [10" id="c-fr-0010]
    10. Use of biotensioactives as an ingredient with prebiotic activity of cosmetic cleaners with prebiotic activity on the skin.
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    JP3563402B2|2004-09-08|Hair and body cleanser
    WO1992018595A1|1992-10-29|Liquid detergent compositions containing natural vinegar
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    FR3070859A1|2019-03-15|CLEANING AGENT BASED ON MICELLES TECHNOLOGY
    JP2005187548A|2005-07-14|Irritation-mitigating additive and low-irritating composition containing the same
    Sen et al.2021|Biotechnologically Derived Bioactive Molecules for Skin and Hair‐Care Application
    同族专利:
    公开号 | 公开日
    GB2544166A|2017-05-10|
    GB201615499D0|2016-10-26|
    DE102015217507A1|2017-03-16|
    US20170071842A1|2017-03-16|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US4395354A|1979-02-22|1983-07-26|Petroleum Fermentations N.V.|αEmulsans|
    US4870010A|1984-10-16|1989-09-26|Petroleum Fermentations N.V.|Bioemulsified-containing personal core products for topical application to dermopathologic conditions of the skin and scalp|
    US5520839A|1993-09-10|1996-05-28|Lever Brothers Company, Division Of Conopco, Inc.|Laundry detergent composition containing synergistic combination of sophorose lipid and nonionic surfactant|
    DE19600743A1|1996-01-11|1997-07-24|Henkel Kgaa|Use of mixture of glyco-lipid and surfactant in hand dish-washing detergent|
    DE102004011968A1|2004-03-10|2005-09-29|Henkel Kgaa|Cosmetic or pharmaceutical composition e.g. useful for promoting the growth of desirable skin microorganisms comprises a plant extract with prebiotic activity on the skin|
    WO2011120776A1|2010-03-31|2011-10-06|Unilever Plc|Mild to the skin, foaming detergent composition|
    CN102370607B|2011-11-01|2013-01-23|江苏省制盐工业研究所|Formula of bath cream with crystal salt and preparation method thereof|
    DE102011090030A1|2011-12-28|2013-07-04|Evonik Industries Ag|Aqueous hair and skin cleansing compositions containing biosurfactants|
    EP2931237B1|2012-12-17|2018-04-04|Unilever PLC, a company registered in England and Wales under company no. 41424 of|Personal care compositions|AU2018266546A1|2017-05-07|2020-01-02|Locus Ip Company, Llc|Cosmetic compositions for skin health and methods of using same|
    WO2019023323A1|2017-07-25|2019-01-31|Dsm Ip Assets B.V.|Use of sophorolipids|
    EP3657980A4|2017-07-28|2021-04-28|Locus IP Company, LLC|Yeast-based masks for improved skin, hair and scalp health|
    US11135151B2|2018-08-31|2021-10-05|L'oreal|Cosmetic compositions containing oxazoline functionalized polymers and compound having at least one nucleophilic site capable of reacting with the at least one oxazoline functionalized compounds|
    US11129787B2|2018-08-31|2021-09-28|L'oreal|Cosmetic compositions containing oxazoline functionalized polymers and polyamine compounds|
    US11166904B2|2018-08-31|2021-11-09|L'oreal|Cosmetic compositions containing oxazoline functionalized polymers and carboxyl group-containing polymers|
    US11154488B2|2018-08-31|2021-10-26|L'oreal|Cosmetic compositions containing oxazoline functionalized polymers and amino silicone compounds|
    DE102019202724A1|2019-02-28|2020-09-03|Beiersdorf Ag|Glycolipid-containing cleaning preparation containing micelles|
    CN110974717B|2019-12-19|2021-08-06|威莱日用品有限公司|Moisturizing baby wet tissue capable of removing dirt and preparation method thereof|
    WO2021185675A1|2020-03-18|2021-09-23|Basf Se|Personal care composition, method for using such compositions and its improvement of deposition effect|
    WO2021236927A1|2020-05-20|2021-11-25|Manhattan College|Silicone-free conditioning cleansing composition|
    法律状态:
    2017-09-28| PLFP| Fee payment|Year of fee payment: 2 |
    优先权:
    申请号 | 申请日 | 专利标题
    DE102015217507.3A|DE102015217507A1|2015-09-14|2015-09-14|Biosurfactants containing cosmetic cleansing agents with prebiotic activity|
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