• 专利附录
  • 专利说明
  • 权利要求
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    • 专利摘要:
    Use of cinnamaldehyde for the treatment and/or prevention of fungal disease Black Sigatoka in banana crops and composition intended for that purpose. The present invention relates to the use of cinnamaldehyde, preferably in the absence of other essential oils, for the treatment and/or prevention of black Sigatoka fungal disease. It also relates to a composition for the treatment and/or prevention of the black Sigatoka fungal disease, characterized in that it essentially comprises at least one first active principle consisting of cinnamaldehyde. In particular, the composition may comprise, in percentage by weight with respect to the total composition: (a) from 1 to 60% of at least one first active principle consisting of cinnamaldehyde; (b) from 0.01 to 5% of at least one surfactant substance; and (c) from 10 to 75% of at least one mineral oil. Another object of the invention is the use of the composition for the treatment of the black Sigatoka fungal disease characterized in that it comprises administering said composition to a banana crop affected by said disease. (Machine-translation by Google Translate, not legally binding)
    公开号:ES2668974A1
    申请号:ES201631491
    申请日:2016-11-21
    公开日:2018-05-23
    发明作者:Sohail Akhter；Kenichi CALDERON-KAWASAKI；Gustavo MADRIZ ACEVEDO；Enrique Gomez Hernandez；Jaidev Rajnikant Shroff；Vikram Rajnikant Shroff
    申请人:UPL Ltd；Decco Worldwide Post Harvest Holdings BV；
    IPC主号:
    专利说明:

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    aggravated by the fact that the areas affected by the black Sigatoka are mostly tropical areas with very valuable ecosystems, but also fragile. This policy of reducing the use of synthetic chemical fungicides is being promoted in producing countries with the objective of protecting the environment, as they are especially polluting compounds. The present invention offers the possibility of being used in alternation with said chemical treatments allowing, if not its complete replacement, at least the reduction of its use. Likewise, the new use of cinnamaldehyde and the composition comprising cinnamaldehyde can be used in admixture with said conventional chemical treatments, at preferably lower doses;
    3. Finally, the claimed composition is a stable formulation compatible with the use of the mineral oils commonly used in the control treatments of banana (banana) diseases, which is free of antioxidants.
    The use of cinnamaldehyde and the composition according to the present invention to treat and / or prevent black Sigatoka fungal disease, as well as the process of treatment and / or prevention of black Sigatoka fungal disease characterized by the fact that it comprises administering cinnamaldehyde, or alternatively the composition described above, to a banana crop affected by said disease. This application can be carried out by means of the same conventional system for applying treatments based on synthetic chemical fungicides to banana (banana) crops in pre-harvest, preferably by spraying or spraying in the field (terrestrial or aerial).
    Detailed description of the invention
    In one aspect, the present invention relates to the use of cinnamaldehyde for the treatment and / or prevention of black Sigatoka fungal disease in a banana crop affected by or potentially affected by said disease. Preferably, in this use, cinnamaldehyde is used only as an active ingredient in the absence of any other essential oil.
    In a non-limiting embodiment, cinnamaldehyde is administered in the form of a composition.
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    - 40% of PEG 400; Y
    - 10% propylene glycol.
    One of the advantages of the composition of the present invention is that it is compatible with synthetic chemical fungicides commonly used in the control of Sigatoka. Therefore, in particular embodiments of the invention, cinnamaldehyde and / or the composition can be used in combination with synthetic agrochemicals as well as known organic active compounds for use in the control of black Sigatoka, so that a synergy that improves the effect achieved with the use of chemical synthesis fungicides, or it can also be used to control the occurrence of strains resistant to said synthetic fungicides. Thus, in particular embodiments of the invention, cinnamaldehyde and / or the claimed composition may be used in combination with at least one synthetic chemical fungicide, or it may be used in alternation of treatments, in which case a series of treatments would be employed. based on the claimed composition, followed by a series of treatments based on at least one synthetic chemical fungicide. Preferably, the chemical synthesis fungicide is selected from among the fungicides authorized for the control of black Sigatoka in bananas (bananas) such as fungicides belonging to dithiocarbamates, carbamates, aromatic fungicides, benzimidazoles, strobilurines, conazoles, amines , anilinopyrimidines, dehydrogenase succinate inhibitors and combinations thereof.
    In one embodiment, cinnamaldehyde can be used in conjunction with, and the composition of the invention may additionally comprise, a dithiocarbamate fungicide.
    Dithiocarbamates can be selected from the group consisting of amobam, asomato, azitiram, carbamorph, cufraneb, disulfiram, cuprobam, ferbam, metam, nabam, tecoram, tiram, urbacida, ziram, etem, milneb, mancozeb, maneb, metiram, polycarbamate, , zineb and any combination thereof.
    In one embodiment, cinnamaldehyde can be used in conjunction with, and the composition of the invention may additionally comprise, a carbamate fungicide.
    Carbamates can be selected from the group consisting of bentiavalicarb, furofanate, iodocarb, iprovalicarb, picarbutrazox, propamocarb and its derivatives, pyribencarb, thiophanate,
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    Banana plants Grande Naine Tissue were used for the test. The experimental unit consisted of 10 banana plants, planted in rows with a distance of 2.5 meters between each plant.
    5 The trial design was completely random and each treatment was replicated three times. In the frontier rows between treatments, Musa textileis was planted, a variety tolerant to black Sigatoka.
    All treatments were applied using a motor sprayer for a volume of
    10 cinnamaldehyde formulation of 2.5 l / Ha. The volumes of the products tested were mixed in an emulsion of mineral oil in a dose of 3 l / Ha of the mineral oil with
    0.03 l / Ha (1% of the mineral oil used) of surfactant.
    Specifically, the following formulations were used for treatment: 15
    Table 1. Formulation 1
    Percentage (weight)
    45.26% Cinnamaldehyde solution, composed of (in percentage by weight): 30% cinnamaldehyde; 10% polysorbate 80; 10% Pluronic®; 40% PEG 400 and 10% propylene glycol
    0.54% Imbirex® (mixture of non-ionic surfactants)
    54.2% Mineral oil (CAS No. 64742-56-9)
    Table 2 shows the compositions used in each treatment, and the amount used for each of them:
    Table 2. Treatments
     Formulation Amount applied (l / Ha)Active principle
    one Formulation 11.5Cinnamaldehyde
    2 Formulation 12.5Cinnamaldehyde
    3 Formulation 16.0Cinnamaldehyde
    4 Vondozeb® (Fungicide)2.0Mancozeb
    5 Spraytex®3.0Mineral oil
    6 Untreated plant--
    The first application was made on May 20, 2015 (week 21) and the last one on August 5, 2015 (week 32). A total of 14 applications were made.
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    Table 4.2
    Formulation YLI Pr 0.0165YLS Pr 0.8030Number of sheets Pr 0.9908Severity Pr 0.0202
    Formulation 1 4.25.17.91.43
    Formulation 1 4.25.27.81.15
    Formulation 1 4.45.38.01.10
    Vondozeb® 62 SC 5.05.67.90.62
    Spraytex® 4.05.17.91.60
    Untreated plant 3.95.17.91.76
    The results of the tests carried out are shown in the figures accompanying this description.
    Keep in mind that the first appearance of symptoms correlates with the severity of the infection. In this way, the smaller the number of leaves in which the symptoms appear, the higher the level of infection.
    10 In all figures, the X axis represents the week and the Y axis: YLI, YLS, total number of leaves or disease severity index.
    Results
    15 The results of the trials allow the following conclusions to be drawn: First, a similar control was observed in all treatments when the YLI (Younger leaf with stripes) was analyzed. In all cases the values were in the range of 3.5-5.0 sheets during most of the test (see figure 2). According to the statistical analysis, there were no significant differences for the YLI
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    20 between the different types of formulation. However, there were differences in the case of treatment with Vondozeb®, untreated plants and treatment with a mineral oil (see Table 4.1); A similar trend was obtained for the YLS parameter (Younger spot stained), since similar results were obtained with the use of Formulation 1. Without
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    However, treatment with Vondozeb® (Mancozeb) had a clearly lower incidence of the disease (the highest YLS values) compared to the rest of fungicides (see Table 4.2 or Figure 3). In this case a statistical analysis was not carried out, since the probability that the YLS values reflected some kind of effect was very low (P = 0.80);


    image15 As shown in Figure 4, the total number of sheets varied between 5.0 and 11.0 during the test period. The behavior was very similar among all the treatments tested, including Vondozeb® and mineral oil. Due to the high infection of untreated plants, the corresponding graphs had a slightly
    5 bottom sheets in the last three assessments. Statistical treatment indicates that none of the treatments had an effect on the number of leaves (P = 0.99);
    image16 As for figures 5 to 7, it is noteworthy that the severity of the disease is the most reliable parameter to assess the differences between treatments. The results show that Formulation 1 is active against black Sigatoka since
    10 the intermediate (2.5 l / Ha) and higher (6.0 l / Ha) doses were significantly more effective than in the case of mineral oil (see figure 5). Although mineral oil does not per se have a fungicidal effect, it favors the distribution of the fungicide and its penetration into the surface of the leaf.
    The above results demonstrate the effectiveness of the composition object of the invention, thus being an effective alternative in substitution of other synthetic chemical fungicides.
    权利要求:
    Claims (1)
    [1]
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    同族专利:
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    WO2018116027A1|2018-06-28|
    CR20190303A|2019-09-03|
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    引用文献:
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    ES2439616A1|2012-07-20|2014-01-23|Decco Worldwide Post-Harvest Holding Co. B.V.|Coating formulation comprising cinnamaldehyde and fungistatic food additives |
    US20140271950A1|2013-03-14|2014-09-18|Griffith Laboratories International, Inc.|Natural Fungicide Composition|
    BR112012028279A2|2010-05-05|2017-05-23|Biomor Israel Ltd|"combinations of antifungal compounds and tea tree oil"|
    US20170079278A1|2015-03-23|2017-03-23|Jose Alejandro Rodriguez Quintero|Enhancer compositions for agricultural chemicals and agricultural chemical compositions|
    CN105165856A|2015-10-26|2015-12-23|广西南宁益土生物科技有限责任公司|Bactericide containing carbendazim and cinnamaldehyde|
    CN105145588A|2015-10-26|2015-12-16|广西南宁益土生物科技有限责任公司|Bactericide containing tebuconazole and cinnamaldehyde|WO2020014205A1|2018-07-09|2020-01-16|Griffith Foods International Inc.|Natural fungicide composition|
    WO2021181112A1|2020-03-12|2021-09-16|UPL Corporation Limited|A composition for control of sigatoka disease|
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    ES201631491A|ES2668974B1|2016-11-21|2016-11-21|USE OF CINAMALDEHYDE FOR THE TREATMENT AND / OR PREVENTION OF FUNGAL DISEASE SIGATOKA NEGRA IN BANANA CROPS AND COMPOSITION INTENDED FOR SUCH USE|ES201631491A| ES2668974B1|2016-11-21|2016-11-21|USE OF CINAMALDEHYDE FOR THE TREATMENT AND / OR PREVENTION OF FUNGAL DISEASE SIGATOKA NEGRA IN BANANA CROPS AND COMPOSITION INTENDED FOR SUCH USE|
    PCT/IB2017/057241| WO2018116027A1|2016-11-21|2017-11-18|Composition for the treatment and/or prevention of the black sigatoka fungal disease in banana crops|
    CR20190303A| CR20190303A|2016-11-21|2017-11-18|Composition for the treatment and/or prevention of the black sigatoka fungal disease in banana crops|
    PH12019500970A| PH12019500970A1|2016-11-21|2019-04-30|Composition for the treatment and/or prevention of the black sigatoka fungal disease in banana crops|
    DO2019000128A| DOP2019000128A|2016-11-21|2019-05-21|COMPOSITION FOR THE TREATMENT AND / OR PREVENTION OF THE BLACK SIGATOKA FUNGAL DISEASE IN BANANA CROPS|
    CONC2019/0005156A| CO2019005156A2|2016-11-21|2019-05-21|Composition for the treatment and / or prevention of black sigatoka fungal disease in banana crops|
    ECSENADI201936192A| ECSP19036192A|2016-11-21|2019-05-21|COMPOSITION FOR THE TREATMENT AND / OR PREVENTION OF THE BLACK SIGATOKA FUNGAL DISEASE IN BANANA CROPS|
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