• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    Device that combines laser technology with ozone and its use in a method of treating fungal infections. The present invention relates to a device (1) for the application of laser technology at different wavelengths in combination with ozone in the gaseous state. For this, a plurality of laser emitters (14) arranged in an electronic plate (13) are used, whose light is radiated on a treatment chamber (2) where a sealed bag (4) with the affected extremity inside is inserted, and in which, through an ozone generation system, a pre-established ozone concentration is insufflated. The device (1) is used as an effective method in the treatment of fungal infections. (Machine-translation by Google Translate, not legally binding)
    公开号:ES2654845A1
    申请号:ES201730753
    申请日:2017-05-31
    公开日:2018-02-15
    发明作者:a mención Renuncia
    申请人:Termosalud S L；TERMOSALUD SL；
    IPC主号:
    专利说明:

    5Field of the InventionThe present invention belongs to the technical field of medical devices for thefungal treatment, and specifically to laser technology combined with ozone toits use in the treatment of fungal infections.
    Background of the Invention Fungal or fungal infections are caused by fungi that infect the skin. They are frequent, contagious diseases and for which there is currently no fast, painless, effective and no side effects universal treatment.
    15 Fungal diseases of the toenails and hands (onychomycosis) are widespread throughout the world. It is a disease whose prevalence has increased considerably in recent decades, reaching figures, according to several authors, of up to 10% of the world's population. That is, 800 million
    20 people affected worldwide by nail fungus. Precisely in the highly developed industrialized countries this chronic pathological picture, which does not tend to self-healing, acquires an ever greater importance.
    Various treatments for these infections are known in the state of the art,
    25 including topical or oral antifungals, laser radiation and surgery. These treatments, however, have important deficiencies, high recurrence and high costs and risks, which makes onychomycosis a disease difficult to cure.
    To improve treatment, new and better ways of treating these infections are being investigated, especially in the field of laser radiation in various modalities, and in combination with other technologies.
    An example is WO2006076506, which describes the treatment of infected nails using radiation and / or another form of energy to substantially deactivate the source of the infection. The treatment can be repeated, and a


    Topical cream or ointment on the diseased nail, cuticle, and / or surrounding tissue or the administration of a medication (for example, oral or intravenous) to prevent recurrence of the organism or to eliminate the unwanted organism.
    5 Another example is WO2011116134, which describes a therapy for infections.fungal with low intensity laser, using a portable laser device thatYou can apply for the treatment of infected hands or feet. The treatment canrepeated, and a topical anti-fungal medication can be applied to help in thetreatment efficacy
    10 However, it is observed that in all treatments of this type of laser infection a subsequent application of medications is needed, reflecting the low efficiency of the laser alone. In addition, direct laser removal of onychomycosis is unsuccessful due to the difficulties of the laser energy to penetrate
    15 the deepest levels of the nail without causing collateral damage.
    Description of the invention The present invention solves the problems existing in the state of the art by means of a device for the application of laser technology at different lengths of
    20 wave in combination with ozone in the gaseous state.
    For this, a plurality of laser emitters are used arranged in an electronic board, whose light is radiated on a treatment chamber where a special sealed bag with the affected limb is inserted inside, and in which, a
    25 through a system of ozone generation, a pre-established ozone concentration is insufflated.
    In one aspect of the invention, the laser system is located in the upper part of the treatment chamber so that the average energy density is the same at all points.
    In another aspect of the invention, the laser system incorporating the device comprises laser emitters that emit in two wavelength ranges. On the one hand, emitters emit at wavelengths in the range of 350nm to 480nm and the rest of laser emitters emit at wavelengths in the range of 590nm to 750nm.


    These emitters are arranged in combination on a printed circuit board in such a way that they generate light radiation with the presence of both wavelengths whose energy density on the affected area inserted in the treatment chamber is uniform.
    5These laser emitters have great efficiency, long life times, sizeReduced and low power consumption.
    In another aspect of the invention, the ozone generating system comprises a
    10 component fixing tray, an oxygen inlet connector through which medicinal oxygen is introduced from a bottle to the device and a female ozone outlet connector from the device.
    In another aspect of the invention, this component fixing tray comprises:
    15 -a ozone generator, which by means of high voltage produces ozone from oxygen, -electrovalves to automate the system to perform the cycles of initial vacuum, filling, treatment and emptying-disposal, -a vacuum pump used for emptying initial of the bag and the subsequent emptying and
    Ozone elimination, -a ozone destroyer, which is a catalytic element to destroy ozone and return oxygen to the atmosphere after treatment and -printed circuit boards for the control of said components.
    In another aspect of the invention, the bag comprises a connector located on one of the sides of the bag and has been designed in such a way as to guarantee the tightness of the ozone inside the bag. This connector is connected to a connection tube that has at the opposite end a male ozone inlet connector to the bag.
    In another aspect of the invention, the bag has a textile fixation structure that ensures that the bag is held on the limb and thus prevents ozone leakage, ensuring that the seal is not lost. In addition, the bag is removable and disposable (one per treatment) due to hygiene and deterioration or alteration due to continued contact with ozone.


    In another aspect of the invention, the device has a screen controlled by a microprocessor to parameterize the laser emission time, ozone concentration and wavelength of the laser emitters, so that it can be adapted to the needs or nature of the type of fungus to treat. With this screen you can
    5 control and exchange information with the user, schedule sessions, control andadjust parameters, etc.
    In another aspect of the invention, the device has an emergency button, to stop the generation of ozone or laser emission in case of electrical failure and / or 10 ozone leakage, providing greater safety to the device and its use.
    In another aspect of the invention, the device is used as an effective method in the treatment of fungal infections.
    15 The device shows that the combination of gaseous ozone and laser light technologies at certain wavelengths manages to eliminate the fungal pathogens responsible for infections in a non-invasive, painless manner and without side effects, therefore being suitable for use in the treatment of fungal infections.
    20 The combined use of both technologies enhances the oxidative stress generated directly by an atmosphere enriched with ozone, allowing the reduction of ozone concentrations used in the treatment and the exposure time to ozone. For this, the device allows to configure the treatment parameters
    25 (ozone concentration, wavelengths, treatment duration, sequence, etc.) for each type of fungus.
    As a consequence of the above, both the exposure time to ozone and the necessary concentration on the tissues to be treated are minimized. In this way the fungicidal effect of the treatment is enhanced, maximizing its effectiveness, achieving a positive effect by combining both technologies.
    Therefore, the device manages to optimize the results against current methods, and allows reducing the effective time to achieve a clinical cure in 35 patients with nails affected by a first infection or recurrence of onychomycosis.


    BRIEF DESCRIPTION OF THE DRAWINGS Next, in order to facilitate the understanding of the invention, by way of illustration but not limitation, an embodiment of the invention will be described that refers to a series of figures.
    5 Figure 1 is a perspective view of the device without the bag, before use, in which the cover of the female connector of the ozone outlet of the device is closed. Figure 2 is another perspective view of the device without the bag, before use, in which the cover of the female connector of the ozone outlet of the ozone outlet is open.
    10 device Figure 3 is a perspective view of the rear of the device where the medical oxygen inlet connector is located. Figure 4 is a perspective view of the device with the bag connected to the ozone outlet of the device for use.
    15 Figure 5 is a vertical sectional view of the device during use with the bag connected to the ozone outlet of the device and inserted into the treatment chamber with the laser system activated. Figure 6 is a front view of the electronic board and the laser emitters, showing the arrangement of each of the types of laser emitters of the device.
    In addition, the emission beam of each type of laser emitter is illustrated. Figure 7 is a perspective view of the bag with the closure element and the connecting tube attached.
    In these figures reference is made to a set of elements that are:
    25 1. Device
    2. Treatment chamber
    3. Component Fixing Tray
    Four. Bag
    5. Textile structure fixing bag
    30 6. Sealing connector
    7. Bag connection tube
    8. Male Ozone Inlet Connector Bag
    9. Female device ozone output connector
    10. Ozone output female connector cover of the device 35 11. Emergency button


    12. screen
    13. Electronic board
    14. Laser emitters
    fifteen. On / off button
    16. Oxygen input connector to the device
    DETAILED DESCRIPTION OF THE INVENTION In view of the aforementioned figures, and in accordance with the numbering adopted, an example of a preferred embodiment of the invention can be observed therein, which comprises the parts and elements indicated and described below.
    Figures 1 to 3 show the device (1), without the bag (4), where the treatment chamber (2) and the main elements of the ozone generator system are distinguished: the component fixing tray (3), the oxygen input connector to the device (16) and the female ozone output connector of the device (9).
    In the upper part of the device housing (1) a screen is located
    (12) controlled by a microprocessor to parameterize the treatment time, ozone concentration, wavelength of the laser emitters and application sequence, depending on the needs of the user.
    On the back of the device (1) there is an oxygen input connector (16), while on the front of the device (1) there is a female ozone outlet connector (9).
    In the component fixing tray (3) there is an ozone generator, solenoid valves, a vacuum pump, an ozone destroyer, power supplies and printed circuit boards controlling said components.
    When the male ozone inlet connector of the bag (8) and the female ozone outlet connector of the device (9) are not connected, the lid (10) is kept closed to protect the female ozone outlet connector of the device. device
    (9) of possible damages.


    On the sides of the device there is, on one side the emergency button (11) to stop the generation of ozone or laser emission in case of electrical failure and / or ozone leakage and on the opposite side the on / off button (15) of the device (1).
    5As can be seen in figures 4 and 5, the device consists of a systemof laser emission formed by a plurality of laser emitters (14) arranged in aelectronic board (13) located on the treatment chamber (2), a tray offixing components (3), and a bag (4) connected by connectors
    10 (8.9) and a tube (7) to the device (1). Said tube (7) is connected to the bag
    (4) by means of a sealing connector (6) that is heat sealed to the bag (4).
    The bag (4) has a textile fixing structure (5) that allows the bag to be held on the user and thus prevents ozone leaks.
    15 As can be seen in Figure 5, the laser emitters (14) are fixed, arranged in a grid on the electronic board (13) located at the top of the treatment chamber (2) to radiate the entire hand or foot of the user, so that the light density is uniform at all points of the treatment chamber
    20 (2).
    In more detail, Figure 6 illustrates the preferred arrangement of the emitters on the electronic board (13). It is observed how two types of emitters are arranged: - Laser emitters (14a) with an emission range from 350nm to 480nm and
    25 - laser emitters (14b) with an emission range from 590nm to 750nm, which combine with each other obtaining a homogeneous dispersion throughout the treatment chamber (2).
    Figure 7 illustrates the bag (4) where ozone is concentrated, which has a
    30 textile fixing structure (5), to prevent leaks and a connecting tube (7) between the male ozone inlet connector of the bag (8) and a sealing connector (6) of the bag for the introduction of ozone .
    Once the invention is clearly described, it is noted that the particular embodiments described above are subject to detail modifications.


    provided that they do not alter the fundamental principle and the essence of the invention.

    权利要求:
    Claims (9)
    [1]
    1. Device (1) that combines laser technology with ozone characterized in that it comprises: 5 - a laser system comprising a plurality of laser emitters (14)
    arranged on an electronic board (13),- an ozone generating system,- a bag (4) in which ozone is concentrated.
    2. Device (1) according to claim 1 characterized in that the laser system is located in the upper part of a treatment chamber (2).
    [3]
    3. Device (1) according to claims 1 to 2 characterized in that the laser system comprises laser emitters (14a) that emit at wavelengths from 350nm
    15 to 480nm and laser emitters (14b) that emit at wavelengths from 590nm to 750nm.
    [4]
    Device (1) according to claims 1 to 3 characterized in that the ozone generating system comprises a component fixing tray (3), a
    20 oxygen input connector to the device (16) and a female ozone output connector of the device (9).
    [5]
    5. Device (1) according to claims 1 to 4 characterized in that the component fixing tray (3) comprises an ozone generator, solenoid valves,
    25 a vacuum pump, an ozone destroyer, power supplies and printed circuit boards controlling said components.
    [6]
    Device (1) according to claims 1 to 5 characterized in that the bag (4) comprises a connector (6) located on one side of the bag and attached to a tube of
    30 connection (7) which has at its opposite end a male ozone input connector to the bag (8).
    [7]
    7. Device (1) according to claims 1 to 6 characterized in that the bag (4)
    It comprises a textile fixing structure (5). 35

    [8]
    8. Device (1) according to claims 1 to 7 characterized in that it comprises a screen (12) controlled by a microprocessor.
    [9]
    9. Device (1) according to claims 1 to 8 characterized in that it comprises an emergency button (11).
    [10]
    10. Device (1) according to claims 1 to 9 for use in a method of treating fungal infections.

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    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    WO1996040298A1|1995-06-07|1996-12-19|R Squared Holding, Inc.|Electrodeless sterilizer using ultraviolet and/or ozone|
    US6254625B1|1998-07-02|2001-07-03|Cenayda V. Rosenthal|Hand sanitizer|
    US20110213446A1|2001-03-02|2011-09-01|Erchonia Corporation|Fungal Infection Therapy with Low Level Laser|
    US20050263387A1|2001-08-17|2005-12-01|Thomas Robert M|Method and apparatus for using ozone as a disinfectant|
    WO2003068275A1|2002-02-12|2003-08-21|Genero Vivanco Bermudez|Method of eliminating pathogenic organisms|
    US20100266446A1|2009-04-20|2010-10-21|Mr.Jimmy Constantacos|Hands and forearms sanitizer|
    WO2017011612A1|2015-07-14|2017-01-19|Vitabeam Ltd.|Methods and devices for sanitation, disinfection and sterilization|US10960094B1|2020-06-16|2021-03-30|Innovative Technologies|Disinfection system|US6960201B2|2002-02-11|2005-11-01|Quanticum, Llc|Method for the prevention and treatment of skin and nail infections|
    US8277495B2|2005-01-13|2012-10-02|Candela Corporation|Method and apparatus for treating a diseased nail|
    CA2632183A1|2005-08-25|2007-03-01|Philip R. Houle|Treatment systems for delivery of sensitizer solutions|
    KR100744716B1|2005-10-07|2007-08-03|김태형|Optical sterilizing apparatus|
    CN101569781A|2008-04-30|2009-11-04|姚广权|Device for curing wound cut|
    CN101829407B|2010-05-14|2012-03-28|武汉海纳川科技有限公司|Semiconductor laser blood oxygen therapeutic apparatus|
    法律状态:
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    优先权:
    申请号 | 申请日 | 专利标题
    ES201730753A|ES2654845B2|2017-05-31|2017-05-31|DEVICE THAT COMBINES LASER TECHNOLOGY WITH OZONE AND ITS USE IN A METHOD OF TREATING MYCOTIC INFECTIONS|ES201730753A| ES2654845B2|2017-05-31|2017-05-31|DEVICE THAT COMBINES LASER TECHNOLOGY WITH OZONE AND ITS USE IN A METHOD OF TREATING MYCOTIC INFECTIONS|
    US16/617,747| US20200108273A1|2017-05-31|2018-05-11|Device combining laser technology with ozone and its use in a method to treat fungal infections|
    EP18725160.8A| EP3630280B1|2017-05-31|2018-05-11|Device combining laser technology with ozone for treating fungal infections|
    PCT/EP2018/062220| WO2018219621A1|2017-05-31|2018-05-11|Device combining laser technology with ozone and its use in a method to treat fungal infections|
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