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  • 专利说明
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    • 专利摘要:
    Enhanced metering systems for managing dosing aliquots feature cartridge housings for exchangeable cartridge with plugs for housing functional substances, extruding conduit tips with fluid flow conduits driven by advancing members for driving amounts of metered functional substance throughout the tips. Manual, pneumatic electrical and/or electronic means for advancing, combined with one way valves, viewing slots, multiple metering and dispensing ports enable two cartridge to be metered at once, as shown by graduated scales.
    公开号:ES2638007A2
    申请号:ES201790019
    申请日:2015-10-13
    公开日:2017-10-18
    发明作者:Aaron Kendziorek；Grayson SULLIVAN Nicholas；Sytze Elzinga；J. DOUGLASS Bradley；Charles RABER Jeffrey
    申请人:Werc Shop LLC；
    IPC主号:
    专利说明:

    METHOD OF DISTRIBUTION MEASUREMENT AND MECHANISMS OF THE SAME FIELD OF THE INVENTION
    The present invention relates to a manual distribution apparatus and, more specifically, to a configuration for the measured distribution of a functional substance. BACKGROUND OF THE INVENTION
    Measured distribution methods are normally used to distribute products so that a precise supply of a specific amount of the substance, such as in pharmaceutical applications, is required for the dosage of a therapeutic substance. Dosage measures may be necessary for topical, sublingual, oral or inhalable therapeutic reasons and may also be useful in the administration of specific functional formulations for non-pharmaceutical uses, such as cosmetic, food, flavor or additives.
    Easy to use, diverse and effective tools for distributing measured formulations are not readily available. Simple approaches such as tincture droppers, staggered syringes or general approaches such as a pinch, a grain of rice, or a phosphorus head to describe the amount is not sufficient for a large number of efficient and effective uses.
    This disclosure provides methods, devices and mechanisms to distribute substances precisely. In addition, it discloses the use of simple devices to aid in the calculation of individualized doses. SUMMARY OF THE INVENTION
    The present invention relates to the manual measured distribution apparatus for the quantitative extrusion of one or more functional substances. Furthermore, the present invention is intended to provide a user with a relatively simple and accurate means for dosing a functional substance. A functional substance disclosed herein is primarily intended to be a composition for exposure to a person, animal, or plant by consumption.
    or topical application; In addition, the substance is intended to provide a function in the context of biological activity or presumed biological activity. In addition, the present invention provides a means for exchanging a functional substance by means of a retained interchangeable cartridge for reuse of a device of the present invention for a plurality of functional substances. BRIEF DESCRIPTION OF THE DRAWINGS
    Figure 1 is a perspective view of a device assembly according to the present invention.
    Figure 2 is an exploded view of a device assembly of Figure
    1. Figure 3 is a cross-sectional view I of an embodiment of Figure
    1. Figure 4 is a cross-sectional view of an embodiment of the present
    invention that uses a member that advances the mechanical turning element.
    Figure 5 is an exploded view of the embodiment of Figure 4.
    Figure 6 is a cross-sectional view II of the embodiment of Figure 4.
    Figure 7 is a detailed cross-sectional view 33 of Figure 6
    rotated 90 degrees from the observation plane to illustrate in more detail and illustrate an interaction between a rotating element and a screw that can advance. Figure 8 is a top view of the mechanism housing of the
    embodiment of Figure 4 illustrating the depressed lobes in a characteristic of
    annular housing
    Figure 9 is a proximal perspective view of a multilobed pin of the embodiment of Figure 4.
    Figure 10 is a cross-sectional view of an embodiment of the present invention employing a stop mechanism capable of advancing.
    Figure 11 is a perspective plan view of the embodiment depicted in Figure 10 that includes a cartridge observation slot.
    Figure 12 is a cross-sectional view III of Figure 10.
    Figure 13 is a detailed cross-sectional view 64 of Figure 12.
    Figure 14 is an exploded view of the embodiment shown in Figure 10
    Figure 15 is a perspective plan view of an embodiment of the present invention employing an electric advancement member.
    Figure 16 is a perspective plan view of an exemplary embodiment shown in Figure 15 that includes an observation slot of the cartridge in the housing of the device.
    Figure 17 is a cross-sectional view of the embodiment depicted in Figure 15.
    Figure 18 is a detailed cross-sectional view 75 of Figure 17.
    Figure 19 is an exploded view of an embodiment depicted in Figure 15
    Figure 20 is a perspective plan view of an embodiment of the present invention employing a pneumatic feed member.
    Figure 21 is a cross sectional view V of Figure 20.
    Figure 22 is a detailed cross-sectional view 122 of Figure 21.
    Figure 23 is an exploded view of the embodiment shown in Figure 20.
    Figure 24 is a distal plan and distal perspective view of an embodiment of the multiple cartridges of the housing of the present invention in a cartridge housing.
    Figure 25 is an exploded view of the embodiment shown in Figure 24.
    Figure 26 is a cross-sectional view of an embodiment of an SSPCRE.
    Figure 27 is a cross-sectional view of an alternative embodiment of an SSPCRE that includes a unidirectional valve.
    Figure 28 is a cross-sectional view of an alternative embodiment of an SSPCRE that includes a distally oriented needle conduit.
    Figure 29 is a cross-sectional view of an alternative embodiment of an MSPCRE that includes a unidirectional valve.
    Figure 30 is a cross-sectional view of an alternative embodiment of an MSPCRE that includes a distally oriented needle conduit.
    Figure 31 is a cross-sectional view of an embodiment of an interchangeable cartridge.
    Figure 32 is a cross-sectional view of an alternative embodiment of an interchangeable cartridge.
    Figure 32 is a cross-sectional view of an alternative embodiment of an interchangeable cartridge.
    Figure 33 is a cross-sectional view of an alternative embodiment.
    of an interchangeable cartridge.
    Figure 34 is a cross-sectional view of an alternative embodiment of an interchangeable cartridge.
    Figure 35 is a cross-sectional view of an alternative embodiment of an interchangeable cartridge.
    Figure 36 is a cross-sectional view of an alternative embodiment of an interchangeable cartridge illustrating a type of variant end film.
    Figure 37 is a cross-sectional view of an alternative embodiment of an exchangeable cartridge housing having a main slot.
    Figure 38 is a cross-sectional view of an alternative embodiment of the present invention in which two devices of the present invention are fixed together in a single device.
    Figure 39 is a cross-sectional view of an alternative embodiment of Figure 10, illustrating the functional action of the present invention.
    Figure 40 is a cross-sectional cross-sectional view of an embodiment of the present invention that includes a heating band associated with the cartridge housing.
    Figure 41 is a cross-sectional view of an alternative embodiment of an interchangeable cartridge housing having a conical proximal end that provides an extrusion conduit.
    Figure 42 is a cross-sectional view of an alternative embodiment of an interchangeable cartridge having an integral conduit tip and the retaining cartridge element.
    Figure 43 is a perspective view from the proximal end of a cartridge having a cross-end valve of end resistance
    proximal DETAILED DESCRIPTION OF THE INVENTION
    Illustrative embodiments and exemplary applications will be described below with reference to the accompanying drawings to disclose the advantageous teachings of the present invention but in no way are intended to limit the scope of the present disclosure.
    In this disclosure, relational terms such as first and second, upper and lower, proximal and distal, upper and lower, and the like can only be used to distinguish an entity or action from another entity or action without necessarily requiring or implying any relationship or order real between such entities or actions. In this disclosure, the use of the term "distal" in relation to the anatomy of the present invention can be used to distinguish the end of the disclosed assembly that is at the far end from the extrusion conduit, while the "proximal" end "refers to the furthest end of the extrusion duct. However, the relative positions and orientations of components or features of a manual measured extrusion device are described and represented for illustrative purposes and are not required unless expressly stated. In addition, accessories or other elements may be distal from the extrusion duct in some embodiments.
    In this disclosure, it will be understood that the term "functional substance" represents a species, chemical composition or mixture thereof that is intended to be a viscous or free flowing liquid, but may exist in solidified state or near solid states when stored. under physical conditions that may alter the physical state of the composition. The functional component may be composed of any individual chemical species or combination of chemical species that have desirable properties and that are suitable for extrusion out of the device and suitable for use in the present invention. In addition, the functional substance does not have to be liquid, but can, for example, be crystalline
    or otherwise solid, without departing from the scope of the invention. The functional substance may comprise a consumable and / or pharmaceutical composition.
    In addition, in the embodiments of the present invention, a cartridge may be composed of a functional substance storage section, which may also be partially or totally surrounded by a protection or otherwise functional housing. In such an embodiment, the reservoir and the housing can be composed of different materials.
    In the embodiments of the present invention, a cartridge may include a proximal end feature, which may serve to retain the cartridge in an extrusion tip section. Such a feature may include helical threads, flexible tabs, magnetic features, or any other suitable mechanism for retaining the cartridge in an extrusion tip. In addition, a closure cap or protective cover can be provided to prevent exposure of the proximal end duct section to the environment.
    In particular, in accordance with one aspect of the present invention, an apparatus for the measured extrusion of a functional substance is provided. The apparatus may comprise providing a measured extrusion of a functional substance. The apparatus may comprise a measured feed member, a housing for receiving and containing a cartridge of interchangeable functional substance, an extrusion conduit, and a detachable associated extrusion conduit cover. The set of components would be configured for the extrusion of a particular volume of functional substance from the proximal end of the conduit duct.
    extrusion.
    An exchangeable functional cartridge, which may sometimes be referred to as "cartridge" or "exchangeable cartridge" herein, suitable for use with embodiments of the present invention may consist of at least one housing and a functional substance. In addition, the ends of The housing can be completely sealed, and when present, the housing can include open ends that can be sealed for storage and shipping by the removable bonded film and / or perforable septa. In addition, in various embodiments, a cartridge may also include a cap at one end, preferably at the distal end, which can serve as a plunger when driven by a piston associated with a metering advance member. In still other embodiments, one or both open ends of the housing can be sealed with a plug, plug or other suitable element that would act to seal the fluid in the cartridge and prevent the inflow of atmospheric gases that can cause adverse reactions with the Functional substance or otherwise spoil the content.
    In further embodiments of a cartridge, a cartridge may include a proximal section that can serve as the extrusion conduit. Preferably, the proximal end section would be of a reduced perforation to provide a user with the ease of placing the extruded substance in a particular location. In such an embodiment, a cartridge may also have suitable sealing ends and bushings to provide adequate sealing and storage conditions while not in use.
    In a further embodiment of a cartridge, a cartridge may include a section or element that can serve to detachably retain the cartridge to a cartridge housing or advance member to deny the need for any other cartridge retaining element.
    As an additional feature of the cartridge of the present invention, a cartridge may include a fluid control valve, such as a unidirectional valve or a fluid flow resistance valve at its proximal end. In embodiments that include a unidirectional valve, the valve would serve to prevent the reverse flow of fluids in the cartridge and to retain a functional substance in the cartridge while it is not in use. In an embodiment that includes a resistance valve, preferably the valve would only allow fluid flow when an appropriate pressure is applied. In such an embodiment, the resistance valve would allow a user to exchange a cartridge whenever desired while avoiding free circulation of fluid outside the proximal end. Only when the pressure is applied by a feed member would the fluid be allowed to flow through the valve. The pressure necessary to "break" the valve will be obvious to one skilled in the art and would preferably be designed to accommodate the ease of use and the function of the present invention.
    In addition, in embodiments of the present invention, a cartridge can be manually inserted and detachably retained in a housing, which in turn can be retained, supported, and / or partially or totally enclosed by an element, feature or retention section. of cartridge.
    In addition, a cartridge housing may be constructed of any suitable material, which may include, but is not limited in any way, to glass, stainless steel, plastic film, brass, aluminum, ceramics or ceramic, plastic, polymeric composite materials, zinc, and coated metals such as nickel plated brass.
    Functional liquids that may be advantageously contained in
    cartridges according to the invention include, without limitation, esters, esters of
    acetate, alcohols, acids, lactones, carbonyls, amides, phenols, isoprenes, terpenes, thiols, saturated and unsaturated thiosulphinates, hemiterpenes, monoterpenes, sesquiterpenes, diterpenes, sesterterpenes, triterpenes, sesquarterpenes, tetraterpenes, polyterpenes, norophenopenes, norophenopenes, norophenopenes, norpenes as terpine hydrate, a derivative of turpentine; natural flavor compounds, such as those often found in fruits, including, but not limited to: Gamma Decalactone, Gamma Octalactone, Butyric Acid, 2-Methyl Butyric Acid, Propionic Acid, Isovaleric Acid, Isobutyric Acid, Cinnamic Acid , Phenethyl Alcohol, Ethyl Butyrate, Ethyl Isobutyrate, Ethyl-2-Methyl Butyrate, Ethyl Isovalerate, Methyl Cinnamate, Ethyl Propionate, Ethyl Hexanoate, Isoamyl Isovalerate, Phenethyl Acetate, (Z) -3- hexenal, beta-ionone, hexanal, beta-damascenone, 1penten-3-one, 3-methylbutanal, (E) -2-hexanal, 2-isobutylthiazole, 1-nitrophenylethane, (E) -2heptenal, furanones, 2,5- dimethyl-4-hydroxy-3 (2H) -furanone, methyl 2-methylbutanoate, 2-methylpropanoate acetate, methyl hexanoate, methyl butanoate, trans-2hexenal, ethyl-2-methylbutanoate, ethyl butanoate, trans-2 -hexenol, hexyl acetate, hexyl butanoate. 1-butanol, 1-hexanol, cis-3-hexenal, cis-3-hexeol, cis3-hexenyl acetate, ethyl hexanoate, propyl 2-methylbutanoate, 2-methyl-1-butanol, benzyl alcohol, 1-octanol , 2-phenylethanol, 1,3-oct-5 (Z) -enodiol, 1,3-octanediol, 4-vinylguayacol, eugenol, 2-methylbutanoic acid, 4-hydroxyphenylacetic acid, 3-hydroxy-beta-damascone, acid
    hydroxy-3-methoxyphenylacetic acid, 3-oxo-alpha-ionol, vomifoliol, 3-οxο-β-ianol, dehydrovomipoliol, roseoside; and / or natural flavor compounds such as those found in vegetables, including, but not limited to: dimethyl sulphide, thiosulphinates, disulfides, poly-sulfides, S-2-propenyl ester of 2-propene-1-sulphothioic acid ( allicin), S-2-propenyl ester of methansulfinothioic acid, S- (E, Z) -1-propenyl ester of 2-propene-1- sulfinothioic acid, S-methyl ester of 2-propene-1-sultinothioic acid, linoleic acid, (E) -2-nonenol, (E) -2-nonenal, (Z) -3-nonenol, (Z) -3nonenal, C9 carbonyls, (Z, Z) -3,6-nonadienal, (E, Z) -2,6-nonadienal, 3-methylbutanoates, 2-phenethyl esters, 2-phenethyl 3-methylbutanoate, (E) -2-hexenyl, 3-methylbentanoate, benzyl 3-methylbutanoate, (E) -2- hexenyl, benzyl 3-methylbutanoate, methyl 3-methylbutanoate, butyl 3-methylbutanoate, 3-methylbutanoate, 3-butyl methylbutanoate, 3-methylbutyl 3-methylbutanoate, (E) -2-pentenyl 3-methylbutanoate, 2- phenethyl, sesquiterpene alcohol, cubenol, phthalides, 3butylfthal uros 3-Butyl-4,5-dihydrophalide, cis and trans forms of 3-butyl-3a, 4,5,6-tetrahydrofhadulo, (Z) -ligustilide, 1- (E, Z) -3,5-undecatriene, sesquiterpene hydrocarbons , alpha-copano, alfa-muuroleno, alfa-caiacoreno, cadinenos, 2-acetil-1prrolina, 2-ethyl-3,6-dimethylpyrazine, acetaldehyde, 3-methylbutanal, 4-vinylguaiacol, 2aceriltiazol, 2-acetyl-2-th (azoline, 2- (1-hydroxyethyl) -4,5-dihydrotiazole, 2,5-dimethyl-4-hydroxy-3 (2H) -furanone, hydrogen sulfide, methanethiol, ethanethiol, octa-1,5-diene-3one, linalool, (E, E) -deca-2,4-dienal, p-mint-1, 3,4-triene, myrcene, 2-sec-butyl-3-methoxypyrazine, myristin, (E, E) -deca-2, 4-dienal, (Z) -dec-6-enal, beta-felandrene, (Z) hex-3-enal, (Z) -hex-3-enol, (Z) -hex-3-enyl acetate, vanillin , menthol, methyl salicylate, 3,7-guaiadiene, delta-cadineno, cannabinoids, nicotine, caffeine, citicoline, and taurine The present invention can also employ a wide variety of melanoidins, a class of chemicals produced by Maillard reactions, in which the amino acids and reducing sugars are heated together to produce complex compositions of chemicals derived therefrom. In addition, alkaloids, steroids, indoles, diazepines, pharmaceutical formulations, therapeutic, biological formulations, protein solutions, recombinant protein solutions, amino acid polymers, natural or recombinant / synthetic deoxyribonucleic acid polymers, natural or recombinant / synthetic ribonucleic polymers, solutions of single or double stranded RNA solutions of natural or recombinant origin, natural or recombinant plasmid solutions, natural or recombinant / synthetic cosmids, viruses, bacteria, fungi, protists, algae, prions, or other microorganisms, particles, organelles thereof , plant extracts, including essential oils, and / or other biological or biologically active components and materials that may be used. CARTRIDGE ACCOMMODATION
    The present invention includes a cartridge housing for housing and / or retaining at least one interchangeable cartridge. As an additional aspect of the cartridge housing, the housing can serve as an anchor for the cartridges, cartridge retaining elements, advancing members with measurement, or other features of the present invention that interact with the interchangeable cartridge. In various embodiments, the housing may integrally contain all or part of certain elements of the present invention, such as an extrusion conduit or an advance member.
    In one embodiment of a cartridge housing, the cartridge housing includes a proximal opening to receive an interchangeable cartridge and a distal end to be at the interface with or be integral with a measuring advance member. Furthermore, in said embodiment, a detachably fixed cartridge retaining element would exist at the proximal end to retain the cartridge in the housing. In a similar, but alternative embodiment, a cartridge that has at least one integral extrusion duct tip and that loosens the anchoring element can be detachably retained by the housing at its proximal end.
    In an alternative embodiment of a cartridge housing, the housing of
    cartridge can receive a cartridge from its distal end in a distal opening.
    In addition, in one embodiment, the cartridge would be retained by a detachable cartridge retainer element detachably fixed, which may comprise a measurement advance member or an adapter for a measurement advance member. In such an embodiment, the housing may include internal features at its proximal end to retain the cartridge within the housing, or it may alternatively accept a cartridge retaining element detachably fixed at its proximal end. The proximal retention element can interact with the cartridge to help retain it in the housing, or alternatively, an extrusion conduit can be detachably or permanently fixed to the proximal end of the housing and would only serve as a fluid flow conduit. In addition, in various embodiments and assemblies of the disclosed elements, the cartridge housing can be constructed to accept a cartridge either from its proximal or distal end.
    As an additional aspect of the previously disclosed features of extrusion duct tips, SSPCRE, and MSPCRE, an extrusion tip or assembly can generally include a feature for interchangeable fixation of a proximal end feature of an interchangeable cartridge to the extrusion tip. In such an arrangement, the interchangeable cartridge could be fixed to the extrusion tip, which results in a complex tip / cartridge that could then be inserted and interchangeably fixed in the cartridge housing. Any suitable anchoring mechanism could be employed, where, for example, a threaded feature of the tip body or the extrusion assembly body.
    In a further embodiment, a cartridge housing may be composed
    of a housing structure and of a heating jacket or element for
    surrounding a cartridge or being in contact with a cartridge in such a way that it supplies thermal energy to the functional substance retained in the exchangeable cartridge.
    In another additional embodiment, a cartridge housing may be composed of a housing structure or associated with an element thereof that can be heated through an external heat source, such as a microwave oven, which can infuse an abundance remarkable thermal energy in the housing itself or the element in order to extend the hot state of a cartridge installed inside it previously or subsequently. In addition, in an embodiment that employs a specific element to retain a large portion of the heat, the material would preferably consist of a substance capable of retaining a significant amount of heat.
    As an additional aspect of the embodiments of the cartridge housings, a cartridge housing may include a graduated scale visible on its exterior to communicate to the user a particular measurement in relation to the amount of functional substance extruded by the device. In addition, to aid in the display of the contents of the exchangeable cartridge, a housing may include a display port on its side, such as a slot. Alternatively, the housing can be constructed of a visibly clear material, such as polycarbonate plastic, that allows the display of its contents. In such an embodiment, a graduated scale can also be included and printed on an interior or exterior surface.
    As an additional aspect of the conduit tips including valves, the valve can be arranged to be located as proximally as possible, so that after extrusion the valve can help retain excess fluid flow from the conduit already avoid extrusion of too much material. In addition, in such an arrangement, the valve can be detachably retained by a protective cover that is also detachably retained. An example of such an arrangement would be a protruding proximal duct tube section, which could retain a valve that has a sleeve section that fits over the end of the tube. In addition, the arrangement could be made to receive a detachably retained cap, which has an axial through hole, which covers and prevents the valve from being pushed out of the end of the tube while still allowing the flow of extruded material from the valve. Such an assembly would advantageously allow a user to install a flow control valve directly at the extrusion point in order to minimize unwanted excess flow from the conduit tube after the extrusion event.
    When an apparatus according to the present invention includes a cartridge having an extrusion duct tip integrated therein, the cartridge can be detachably retained in a cartridge housing by a retaining element that only serves to block The cartridge in the housing. The element may comprise an annular object that can be screwed on or otherwise be able to be anchored in a cartridge housing and claim or otherwise secure a cartridge in position. In a further embodiment, a cartridge having a housing retention element integrated in the cartridge could similarly have an anchoring mechanism to retain the cartridge in the housing but would not require any auxiliary part to retain it in the housing. PROXIMAL CARTRIDGE RETAINERS
    When an apparatus according to the present invention includes a proximal cartridge retaining element, the cartridge retaining element may comprise a single section or two or more separate sections connected detachably or immovably with each other. In any embodiment of the proximal cartridge retaining element, the element as a whole would serve to retain at least one cartridge of interchangeable functional substance in or to a cartridge housing and in some embodiments a fluid flow conduit through the body can also be provided from its axial end to the end that can
    or it cannot be interposed by other functional elements, such as valves or other features. SINGLE SECTION PROXIMAL CARTRIDGE RETENTION ELEMENT
    When an apparatus according to the present invention includes a single section proximal cartridge retaining element, alternatively referred to as "SSPCRE" herein, the element would be composed of at least one characteristic at its distal end for connection to a housing. of cartridge at the proximal end of the cartridge housing, a fluid flow conduit from its axial end to the other, and may or may not include several features or elements provided in line with the fluid conduit. In addition, an SSPCRE would contain a fluid flow conduit from one end to the other made to be in fluid communication with a functional substance retained in an interchangeable cartridge and a port or hole at its proximal end to allow extrusion of the functional substance out of the proximal end of the assembly thereof. In addition, the single section proximal cartridge retainer can also accommodate other elements such as unidirectional valves, heating elements, or other functional elements interposed between the SSPCRE and the cartridge housing. In addition, the SSPCRE can also partially accommodate an exchangeable cartridge end if the cartridge protrudes from the cartridge housing to some extent. As an additional feature, the SSPCRE may have a tapered needle section around the fluid flow conduit in a distal position to pierce a septum and / or film at the end of an interchangeable cartridge. In addition, the SSPCRE may contain a septum or septum to accept a needle from an external device to refill a housed exchangeable cartridge or to accept the fluid flow of the present invention. As an additional feature, the SSPCRE may contain a heating element, such as a resistance coil or any other suitable heating element. As another additional feature, the structure of the SSPCRE may include geometric features, such as grooves, electrical contacts, or other features that allow a favorable interface with external devices or objects. As a whole, the SSPCRE could function to retain an interchangeable cartridge, provide a fluid flow path for extrusion, provide a heat source, and can also provide other features for engaging with external devices or presenting reverse fluid flow through the unidirectional flow control. ELEMENT OF RETENTION OF PROXIMAL CARTRIDGE OF MULTIPLE SECTIONS
    When an apparatus according to the present invention includes a cartridge retaining element composed of multiple sections, alternatively referred to as "MSPCRE" herein, the element assembly would have at least one feature, or section, at the distal end of the assembly. or feature of a section to detachably connect the proximal end of a cartridge housing. In addition, the element would include a fluid flow conduit from one end to the other in fluid communication with the functional substance retained in an exchangeable cartridge and an open end of the fluid flow conduit at the proximal end of the set of sections that would allow the extrusion of the functional substance at a particular location outside the proximal end of the present invention.
    In an embodiment of an MSPCRE consisting of two distinct sections, the two sections would comprise a first cartridge retention section for connection with a cartridge housing, retaining an exchangeable cartridge, and establishing fluid communication with a functional substance. The second section proximal to the first would function as an extended extrusion duct tip having an open fluid flow duct through its core. In addition, in alternative embodiments, interposed between the two sections or integrated with one or both of the sections there would also be additional features, elements or sections that may provide other desirable functions, such as a unidirectional flow, a different housing section for a valve unidirectional flow, a septum, a flow limiter, a heating element, an adapter for the rapid exchange of extrusion duct tips, or any other feature or element that can improve the function of the apparatus. In addition, the MSPCRE can be composed of several sections, which can collectively compose any portion or feature of the previously disclosed embodiments or features of the extrusion duct tips or the proximal single section cartridge retaining elements. ATMOSPHERIC EXPOSURE REDUCTION
    As an additional detailed description of the previously disclosed features of extrusion duct tips, SSPCRE, and MSPCRE, the elements may provide a system to reduce atmospheric gas exposure by including a reduced diameter hole, a pierceable septum, and / or include a unidirectional valve that allows the flow of functional substance out of the exchangeable cartridge, while also preventing the influx of atmospheric gases into the cartridge. In embodiments employing a perforable septum, the septum would preferably consist of an elastomer and / or polymeric film or a series thereof, which could be pierced with a conduit needle. In addition, preferably the septum material would consist of materials resistant to chemical substances, which could also be used in applications for exposure to food products. Exemplary materials are silicone, PTFE (polytetrafluoroethylene), Viton ©, Nylon, PEEK (polyether ether ketone), and BOPET (biaxially oriented polyethylene terephthalate) but would not be limited to such materials. In all cases, a person skilled in the art would recognize the appropriate materials, applications and uses thereof.
    In addition, embodiments of such elements that employ a unidirectional valve can use any suitable valve, but for example they could employ duckbill, umbrella, duckbill / umbrella, transverse groove, dome, or ball. Preferably, the valves would consist of materials resistant to chemicals and suitable for exposure to food, such as silicone, fluorosilicone, fluoroelastomer, polyisoprene of natural rubber, butyl, propylene ethane, nitrile, or any other suitable material, but not limited to such materials. In all cases, a person skilled in the art would recognize the appropriate materials, applications and uses thereof. DIFFERENT CARTRIDGE RETAINING ELEMENTS
    In accordance with the present invention, in certain embodiments, a cartridge housing may have an opening at its distal end to receive an interchangeable cartridge and a cartridge retainer to retain the cartridge in the housing. In such an embodiment, the cartridge retaining element may be a composition of a retaining element and a metering advance member or simply a cartridge retaining element that may be at the distal end of the assembly or interposed between the accommodation and the advance member with measurement. PROXIMAL COVER
    As a further aspect of the present invention, preferably the device could be provided with a detachably retained proximal cover, alternatively referred to as "proximal cover" herein. The proximal cap is proximal to the extrusion duct element and would serve to cover the exposed end of the extrusion duct to prevent further atmospheric exposure, contain accidental leaks, prevent damage to the duct, avoid possible injuries that could arise from stabbing with a reduced end of the extrusion conduit, or be provided for general storage and aesthetic purposes. In embodiments that have multiple extrusion ducts, multiple proximal caps can be provided. PROGRESS MEMBERS WITH MEASUREMENT
    In accordance with the present invention, a cartridge housing could include
    or have an advance member with measurement associated with it. Such a mechanism would interact with a cartridge of interchangeable functional substance at its distal end by actuating a piston or a screw in or, otherwise, acting on or compressing a functional substance outside the interchangeable cartridge at its proximal end. In addition, the advance member would preferably include a measuring capability that would allow a user to advance the drive a desired amount, either by visual indication, by tactile feedback, or by both at the same time. In addition, in various embodiments, an advance member with measurement may include visible graduation scales to indicate to a user advance distances and the volume content of the cartridge. In addition, the piston, screw or other suitable advancing element may have a permanently associated piston plug for actuating the functional substance out of the interchangeable functional substance cartridge or, otherwise, may interact with a plug previously installed in a cartridge to provide the same result.
    A measuring advance member of the present invention could function to drive the flow of functional substance out of the exchangeable cartridge in a measured and controlled manner. In all embodiments of an advance member with measurement, the advance members would act at the distal end of an exchangeable cartridge, apply a pressure to a substance retained with a plunger, and push the functional substance out of its proximal end. Alternatively, when a cartridge having a housing made of a flexible film substance is used, a feed member can progressively squeeze the housing to force extrusion out of the cartridge, such as with a plate or with rollers.
    In accordance with the present invention, a metering advance member may be composed of any suitable mechanism that performs the intended function of the present invention. In particular, various embodiments are described in detail herein, but it should be appreciated that many alternatives and mechanistic designs and features thereof, such as electrical elements, are contemplated and envisioned and that one skilled in the art will recognize that the mechanisms and features disclosed herein may generally be extended.
    to other variations without departing from the scope of this disclosure.
    In addition, in various embodiments, the measurement advance members disclosed herein can be coupled or combined with any other feature of the invention, whether partially or totally, such as the cartridge housing, the fixing adapters, the elements. of cartridge retention, or other features disclosed herein. For example, a mechanism housing can be combined with a cartridge housing to comprise a single part. Furthermore, said advance members can optionally be controlled through wireless communication mechanisms. DISCLOSURES OF THE SIMPLE MECHANISM
    In one embodiment of a metered advance member, the measured advance member would consist of a mechanism housing, a piston rod, a finger grip, and a distal end cap of the housing. In one embodiment, the housing of the mechanism can be combined with a cartridge housing, to represent a single part, and can with its inner perforation that slidably engages with a grip for attaching them to a piston rod, to the rod of the Plunger only, or both at once. Together, the finger grip and the rod would maintain axial alignment within the housing to allow the piston rod to interact with the interchangeable cartridge and drive the flow of the functional substance. Alternatively, the finger grip would be associated with the piston rod and the piston rod would be slidably coupled with an annular groove interposed between the cartridge and the advancing member that would keep the piston rod in axial alignment with the cartridge. In all variants, the mechanism housing would provide a groove for the finger grip to pass through it, which would also abut a graded scale indicated on the visible outer surface of the housing to indicate the relative position of the plunger and advance distances possible or already made. Furthermore, in both cases, preferably the distal end of the housing would have a cover or lid that can be permanently or detachably retained to allow initial construction.
    or the intermittent deconstruction of the set. In an alternative embodiment, a similar arrangement could be provided, in which a tactile feedback mechanism would be included, in which a finger grip portion would interact with raised or recessed features, in series, along the length of the groove and, as the finger grip is pushed through the groove, the finger grip element, which could for example be a spring-loaded metal flange, would form a resistive contact with the groove characteristics as each feature It is passed. Such a mechanism could be used to indicate the advance of a defined distance corresponding to a defined volume of the extruded functional substance. In all embodiments, preferably the sliding action of the plunger would be accompanied by a moderate resistance to movement so that the rod does not slide freely back and forth without the force generated by a user's hand. SCREW AND CLICK
    In an alternative embodiment of a metering advance member, the metering advance member may comprise a screw driven plunger and an element rotated by a user to drive the screw plunger. In embodiments using a piston or piston rod of the screw-operated piston, the screw can be actuated by the turning action provided by a user. In various embodiments, the advance of the screw can be accompanied by tactile feedback, such as a click action. In addition, in various embodiments, the travel distance can be preset or adjusted by the user.
    Furthermore, in one embodiment, the advance of said plunger screw could be provided by a rotating actuator element by a user who does not travel in the proximal or distal direction, but rather would only rotate in its position around its axis. This could be achieved by using a plunger with, for example, a square or rectangular shaft having two flat faces, and two externally threaded radial faces. With such an arrangement, the shaft could be rotated by manual rotation by the user of the rotating element, which would apply a force on the flat faces of the shaft while the threads interact simultaneously with a stationary threaded hole in the housing, making that the screw advances along its axis in accordance with the pitch of the helical thread. In addition, the manually rotated element would allow the shaft to slide through its body along the flat faces as the screw advances. In such an embodiment, the manually rotated element may be visibly clear and may have a graded scale printed., Which could be located circumferentially around the rotated element, which would coordinate with the position of the distal end of the screw shaft to indicate the user the position of the screw in relation to the cartridge.
    In addition, in a further embodiment, the manually rotated element may have associated therewith a composition of elements that can provide tactile feedback when the element capable of being manually rotated is rotated to indicate a certain advance of the element. In one embodiment, the element capable of being manually rotated can retain a length of metal sheet or wire of the spring with a radially protruding flange or elbow that would interact with an internal diameter groove of a hollow cylindrical housing. In such an arrangement, the metal flange of the spring would interact with a series of raised features of the groove to produce a spin resistance and tactile feedback in the form of a "click."
    In an alternative embodiment, a spin resistance and tactile feedback in the form of a "click" could be provided by rotating coordination of an element capable of being manually rotated with a multilobed pin with protruding lobes having a hole drilled through its center to allow the free passage of a dual flat face feed screw. In addition, the multilobed pin would be arranged to be forced into and interact with the coupling arrangement of lobes recessed in an annular section of the mechanism housing, which would also have a threaded hole in its center to engage with the lead screw. In addition, as a final feature, the multi-lobed pin would be forced into the recessed lobes with a metal spring resting against a groove in the element capable of being manually rotated. In concert, as the element capable of being manually rotated is rotated, the multilobed pin is forced to rotate with it and is pushed up from the ridges of the hollow lobes and out of the depressions of the lowered lobes. As the pin is pushed up, and rotates on a lobe crest, it presents a resistance to rotation and is advanced slidingly towards the distal end of the assembly in a groove provided for its displacement. Once the rotation has allowed the multilobed pin to fall back into the depressions of the lowered lobes, the force of the spring causes it to snap into the lowered lobes. As a result, the process produces a tactile feedback in the form of a "click" to the user who rotates the element. In such an embodiment, the element capable of being manually rotated can also have a visible scale to coordinate with the position that the screw can advance. In addition, in such an embodiment, the rotation could occur in any direction, allowing a user to return the screw to a fully retracted position, which allows cartridge replacement.
    As an additional aspect of the embodiments of a metering feed member in which a tactile feedback feature would be employed, the mechanism may employ a "click" touch feedback that would indicate the actuator advance in a predetermined amount or in a quantity selected by a user. The term "click" infers either the generation of a single sound, tactile feedback, or both. In addition, in the preferred embodiment, the advance of the mechanism could also be visually indicated to the user as a quantity or advance along a graduated scale.
    For the generation of a tactile response associated with an advance, several mechanisms could be employed to achieve the function. In one embodiment, the depression of an element associated with the mechanism could be used to produce a short and preset advance of the actuator by actuating a piston or a screw or a short distance or rotation. In addition, in such a mechanism the depressed element would return to its original position to allow additional advances. Such a mechanism would appear similar to a retractable pen. STOPPING MECHANISM CAPAZ DE AVANZAR
    In other embodiments of a measuring mechanism, the mechanism may comprise a depressing piston limited by a stop capable of advancing, in embodiments employing these elements, the stop block would preferably be able to move towards the proximal end of the assembly and housed within the There would be a depressing piston itself. In such embodiments, the advance of the stop would preferably not engage the depressive piston while advancing and would remain in its original position until it is operated and depressed by a user. Functionally, the interdependent association between the two elements could allow a user to advance the stop a desired distance before actuating the piston and subsequent extrusion of a functional substance out of the interchangeable cartridge at its proximal end. Once a user wishes to depress the piston and expel the functional substance, the user would apply pressure at the distal end of the piston - depressing it until it contacts the stop. The mentioned mechanism and process would allow a user to select a volume of functional substance to be expelled, then expel the volume in a single rapid event.
    In one embodiment of the present invention, an advance member consisting of a stop capable of advancing and a depressing piston may comprise an assembly in which a stop capable of advancing may consist of an axial bore and an internal helical thread coupled with a external helical thread at the distal end of a cartridge housing, whereby the rotation of the stopper capable of advancing would result in a displacement of the cartridge housing, whereby the rotation of the stopper capable of advancing would result in a movement of the housing of cartridge. Preferably, the stop capable of advancing would be mounted in such a way that after reaching the limit switches the stop capable of advancing stops. More particularly, by limiting the stroke, a user would have no problem involuntarily decoupling the threads by unscrewing the part at its end of stroke at the distal end of the cartridge housing. This can be achieved by the use of snap rings during manufacturing assembly or by other characteristics of the two components. When used, a pressurized ring may consist of a ring that has open and disconnected ends that are partially recessed to allow partial compression of the ring towards its axial center. In various embodiments, the ring may consist of a wire of several profiles formed in an annular structure or it may be a ring produced by stamping. The wire profile can be round, square, triangular, or have any other geometry that can serve the stop function and would not be limited to such profiles. In addition, in such an embodiment, preferably the stop block could be made advancing in the distal to proximal or proximal to distal direction, in which the latter would allow a user to exchange a spent functional substance cartridge with a new cartridge.
    In embodiments that employ a stop capable of advancing and a depressing piston, preferably the advance member would have associated with it a visible indication of the position and distance of advance. The visible indication could be provided by a graduated scale, multiple scales, or multiple graduated scales that visibly interact with each other to indicate a position. In embodiments employing a single graduated scale, the scale would preferably be in a visible section of the apparatus and could be partially or fully covered or made invisible as the stop capable of moving moves - thus indicating the advanced distance or the distance still Available for advancement. Multiple scales may be used in a single set of the present invention in which one scale may indicate a different graduation scale from another. For example, one scale can indicate a mass in milligrams, while another can indicate a volume as milliliters.
    In one embodiment, a pair of graduated scales can visibly interact with each other to indicate progress. For example, a scale spanning an axial length proximal to distal would be indicated on a visible surface, such as the outer surface of the cartridge housing, while a scale indicated on the outer circumference of a stop capable of advancing may exist towards its edge. main proximal In such an embodiment, the stopper capable of advancing would partially surround the indicated cartridge housing and be coupled with a helical thread in the housing. The turning of the stop capable of advancing would cause it to cross a length of the housing and, consequently, the scale indicated in the housing. Together; the turn scale indicated on the stop capable of advancing would indicate a fractional advance of a graduation on the scale indicated on the housing as the turn occurs. For example, the coupled thread can have a pitch of 1 mm and the graduations of the housing can be interleaved at a distance of 1 mm. A total turn (360 degrees) by a user would make the stop capable of moving through 1 mm of the housing, but it could be that a user would like to be able to cross a smaller distance while a finer graduation is still available to indicate the resulting displacement caused by a partial turn. In such an arrangement, the finest graduations would be indicated on the visible surface of the stopper capable of advancing and coordinated with a mark on the cartridge housing to provide an indication of the displacement resulting from a partial turn.
    In further embodiments of the present invention that employ a stop capable of advancing and a depressing piston, the stop capable of advancing may include a tactile feedback mechanism or friction resistant element to indicate to a user a certain displacement of the stop capable of advancing. In an embodiment that employs a stop capable of advancing, a friction-resistant element or tactile feedback of the click type can be used to indicate the displacement
    of the stop in relation to a total or partial turn.
    In further embodiments of the advance members with measurement, various embodiments may include an electronically driven and controlled drive of the advance piston. In such mechanisms, an electronically controlled actuator would preferably be able to be controlled by a user through interaction with buttons or other control interfaces associated with the housing. The electric drive can be driven by a motor or a solenoid. Other embodiments of the electrically driven drive can be wirelessly connected to a controller through a human interface.
    In embodiments consisting of an electronic motor driven drive mechanism, the system would preferably consist of a user interaction interface, an electronic control circuit, a battery, an electronic motor, a power transfer system, a piston capable of advance, and accommodation.
    As an additional aspect of a user interaction interface, the interface may simply be a single button or switch, or it may comprise multiple buttons, keyboards, or other switching elements that would be in electrical communication with the electrical control circuit, in addition, A user interaction interface may include a display screen controlled by an electronic control circuit. In addition, manual switches or buttons may comprise any type of mechanical switch, such as a push button, or a slider, rotary knob or collar; or an electro-mechanical switch, such as a touch screen or other rugged sensor that may, for example, be comprised in a display / control panel or connected wirelessly.
    As an additional aspect of the present invention with respect to the present
    embodiment, a selectively attachable thread system can be used to
    allow the user to slide the stop capable of advancing along its axis without turning until the user chooses to engage the helical thread that is used to advance the stop capable of advancing when a volume of extruded product to be extruded is selected. Such a composition would work by mechanically coupling or uncoupling the helical threads of the cartridge housing and the rotating element capable of advancing. For example, in such a case, the cartridge housing section may include a plurality of threaded blocks that can be retracted away from or extended out to the point of engagement. In one embodiment, the cartridge housing would be arranged to have a series of radial grooves to accommodate radially extensible blocks, each with a single helical threaded face protruding outward. The blocks can be extended and retracted through any suitable mechanism, where, for example, in the case of three blocks, a lobed cam can be placed below the blocks towards the central axis, where the lobed cam is rotated by the pin of the plunger. The blocks can be retained towards the central axis and in the housing grooves by a circular spring, such as a toroidal spring or extension spring connected to the end. In such an arrangement, the cam lobes are designed to push the blocks radially outward to a degree where their threaded faces mate with the internal thread of the rotating element capable of advancing from the stop capable of advancing. While in this state, the threads would engage and the rotation of the stopper capable of advancing would result in a displacement through the cartridge housing with respect to the passage of the helical thread. When a user wishes to decouple the thread to retract the stop capable of advancing to a new position to avoid inconvenient screwing action, the user could twist the plunger pin, causing the blocks to retract to the lower section of the lobed cam, disengaging from the thread, and releasing the stop able to advance the thread. The re-coupling of the thread could be done by turning the plunger pin once more to a position where the lobes push the blocks back to a thread coupling point.
    In one embodiment, the control circuit includes a memory storage element capable of recording and storing user-relevant usage data, as well as any other information supplied to the device by means of electrical communication by any of a direct wired connection or a wireless communication mechanism These data may include, for example, the cumulative consumption of the functional substance in a given period of time; volumes of functional substance use by the user; time periods between uses; temperature profiles of one or more components; history of energy consumption; stored preferences or settings; and alternative modes of use, such as previous combinations of components connected in the device assembly, and in what order they are connected, and / or particular encoded information that identifies the attributes of a component, such as its serial number part, a flavor or substance that it contains or may contain, for example. In addition, stored data can be used by processing units to control the mechanisms of the present invention. One skilled in the art will appreciate that these types of data are disclosed by way of example and should not be considered as limiting the scope of the information that can be stored in the memory storage element within the scope of the invention.
    Preferably, an electronic controller includes one or more processing elements / processors. For example, processors could be used to determine what is displayed on the display / control panel and / or to automatically trigger the members or advance elements according to the data and logic processed by the processors. One skilled in the art will appreciate the various extensions of the use of processors in the present invention, which are in no way restricted to the processing examples disclosed herein.
    As an alternative to the simple manual drive, the drive of a feed member can occur automatically in response to the entry of an access code that matches a valid access code stored in a controller memory. As an alternative, a correct access code entry can only "unlock" the device's advance function, without automatically initiating the advance, but instead allowing a user to activate the manual advance. For example, after the access code is successfully validated, a user can press a simple button or switch to start actuation. The atomization element may respond to a single manual drive after the access code validation, a predetermined plural number of manual drives, for a predetermined amount of time elapsed after the access code validation, or until the processor receives a affirmative user order to "lock" the device again, such as re-entering an access code to change back to a locked state, or by a simple switch or manual button. The password can be entered by a user directly in the screen / control panel or communicate to the controller from a separate input device or tab, such as a user's personal smartphone, magnetic card, barcode image, through a Wi-Fi network, infrared, Bluetooth ®, RFLD, or optical connection, for example.
    In one embodiment, the controller may also include or connect.
    operatively to a wireless communication element (not shown in the Figures) capable of transmitting to another wireless communication device or receiving information from said wireless communication device. In general, many types of wireless network are contemplated in this disclosure and may include, but are not necessarily limited to WFAH (Wireless Personal Area Network), WLAtsl (Wireless Local Area Metwork), WAN (Ares Network), or any other network adequate wireless and types of communication. Advantageously, the wireless network connectivity allows the distribution devices according to the invention to communicate with or be controlled by a personal electronic device such as a smartphone, for actuation purposes enabled by access code or lock / unlock of one or more functions of the distribution device (obviating the need for a multi-key user interface on the inhalation device itself), as well as facilitating the control / monitoring, storage and analysis of usage data in the personal electronic device.
    Furthermore, as an additional aspect of the electrical control circuit, preferably the circuit would be designed to be able to receive and transmit an electric current from a charging cable to a battery or heating element, in addition to including electrical communication elements for the transmission of data between device 130 and external computing and / or data storage devices. In one embodiment, a connection port (not shown in the Figures) at the proximal end of a battery / controller housing or in the extrusion conduit can be coupled with other elements that extend proximally or distally therefrom. When included, such a connection port can also allow electrical communication of the circuits with one or more drive mechanisms.
    As a further aspect of the present invention, the cartridge housing
    or the advance member may have associated with them a scanner or sensor for the detection of data or data of an interchangeable cartridge or other object that can then be shown to a user in the device with an electronic display or used by the electronic circuit control to alter the drive according to the received data.
    Advantageously, the electric controller can be designed to regulate the battery charge rate with respect to voltage and current and could avoid battery overload. In addition, preferably the electrical control elements could prevent the reverse polarity damage in the circuit elements or in the battery, by incorporating appropriately configured elements such as diodes, PNP transistors, or a FET P channel.
    As an additional aspect of an electronic motor for use in various embodiments, the motor can be driven by alternating or direct electrical current and would be in electrical communication with a control circuit. In a very simple embodiment, an electrical control circuit may simply comprise an electrical communication between the motor and a battery, interposed by a power switch. In the most advanced mechanisms, the control circuit may comprise other features disclosed herein and also be in electrical communication with the electric motor. In addition, in an alternative embodiment, the advancing member may include multiple electric motors.
    As an additional aspect of a power transmission assembly, the power transmission may comprise a series of straight tooth gears, worm gears, helical gears, planetary gears, or any other gear suitable for transferring the rotational force of a electric motor to a feed piston. Alternatively, in a further embodiment, a driven belt or friction clutch systems can be employed. PNEUMATIC SYSTEM
    In a further embodiment of an advance member with measurement, a pneumatic system can be employed by using a portable compressed gas container in association with an advance mechanism. In such an embodiment, the gas pressure provided by an on-board pressure vessel, such as a compressed carbon dioxide gas cartridge / tank, which can be interchangeable or integrated and refillable, could be used to drive a piston. pneumatic cylinder. In one embodiment, the compressed gas tank can be exchanged through a port in a distal part of the device housing or a proximal portion of the device housing. In another additional embodiment, the compressed gas tank can be exchanged through a hinged door
    or sliding door on the side of the device housing. In a further embodiment, the device housing may have a groove permanently cut off the side of the device housing to allow the tank to be exchanged from that side. In all embodiments, preferably the interchangeable tank would be reliably mounted in one position and in relation to a valve assembly in order to avoid excessive gas leaks from its connection points where the pressurized gas is made to be in fluid communication with the device or elements thereof.
    In various embodiments of a pneumatic embodiment of the present invention, the piston could drive a piston rod to drive the flow of functional substance out of a cartridge. In embodiments employing a pneumatic cylinder, a single-drive, double-drive or telescopic cylinder design could be employed, as well as cylinder arrangements that have a return spring to cause the piston to return to its original / initial position when not It provides pressure. The actuation of the pneumatic piston is preferably controlled by a valve mechanism that intervenes between the pressure reservoir and the pneumatic cylinder. In addition, preferably, the valve assembly would allow a user to change the flow rate and pressure supplied to the cylinder and also includes a switch, such as a depressive button to allow a user to conduct the flow manually. In an alternative embodiment, a screw driven by a rapid flow of compressed gas through a turbine or other similar element could be used to advance a screw driven actuator. In still a further embodiment, the valve assembly can accept a pressurized gas or other fluid from an external line, such as a gas line from an air compressor
    In a further embodiment of the present invention, a cartridge housing may comprise multiple cartridge retention sections, in order to allow the containment of multiple interchangeable cartridges in a single housing. In addition, in such an embodiment, a single feed member can be used to functionally operate with multiple cartridges individually or simultaneously. In such an embodiment, the mechanism would require an additional mechanism to move the feed member to each cartridge. In one embodiment, a cartridge housing can contain multiple cartridges distributed in a radial matrix shape, whereby a single feed member can be advanced from one cartridge to the next by radially rotating the mechanism from one cartridge to another along the pattern of cartridge distribution matrix. This can be achieved by adding a feed member in a central spindle that would allow the feed member to reach each rotated cartridge to the location of the cartridge.
    In an alternative embodiment, a multi-cartridge housing that is operated by multiple feed members associated with one or more cartridges can be employed.
    In addition, in an alternative arrangement, the advancement members of the housing of multiple individual cartridges can be fixed together in a single unit by means of an adapter or other element that can fix them together in a single multi-operative unit.
    In a further embodiment, a plurality of cartridges can be arranged such that the extruded functional substance of each cartridge can be combined in a shared flow path to provide comfort to a user and / or facilitate in situ mixing of substances before the Fine extrusion of the present invention. In one embodiment, a user may choose to extrude only one substance at a time, or, alternatively, a user may mix two or more functional substances with one another by means of an element of the present invention before final extrusion. In one embodiment, a single meter can be used to operatively select the volume of extruded product from each of multiple cartridges. In another embodiment, multiple meters can be used to provide a user with the ability to select a given volume of extruded product from each cartridge. In another additional embodiment, a mechanism can be employed whereby the speed and amounts of extrusion can be controlled individually for each cartridge at the same time. In such an embodiment, an electronically or pneumatically driven feed member can be used to provide selective control of extrusion rates of each of the multiple cartridges. In one embodiment, a proximal cartridge retaining element can provide ease and / or conduct the mixing of multiple substances and the final extrusion. In other embodiments, the proximal cartridge retaining element may be composed of multiple sections or elements. In addition, in alternative embodiments, the cartridges may be retained by distal elements and mixing and / or mixing mechanisms may exist as integral features of the cartridge housing or housings.
    As an additional aspect of all the embodiments disclosed herein and provided in the scope of the present invention, the materials from which the components are preferably constructed may comprise rigid materials such as metals and plastics, opaque or transparent substances, such as Plastics or colored glass or optically transparent. In addition, a person skilled in the art will recognize the appropriate material options for various embodiments and variations thereof and no component should be limited in any way to a particular construction material or manufacturing method. DETAILED DESCRIPTION OF THE DRAWINGS
    In accordance with aspects of the present invention, various embodiments of the present invention and its components will be described in greater detail below with reference to the Figures and drawings.
    According to an embodiment of the present invention, a schematic drawing of a complete measured distribution device 1 incorporating a feed member driven by a manually movable slide is presented in Figure 1. The assembly first comprises a cartridge housing 2 with a proximal cover installed; integrated with the cartridge housing is the feed member consisting of a housing 2, a finger grip 5 associated with a piston (not shown), a feed slot 6 to allow the travel of the finger grip, a housing cover distal 4 to retain the sliding piston, and a visible graduated scale 7 to indicate the relative position of the piston rod. As a further detail, an exploded view of the measured distribution device 1 is presented in Figure, 2 and a cross-sectional view is presented in Figure.
    3. Figure 2 and Figure 3 provide additional details of the internal components, wherein the assembly first consists of a proximal cover to cover the tip 11 of the extrusion conduit; a tip 11 of the extrusion conduit having a fluid flow conduit 13, which may alternatively be composed of several sections or elements in various previously disclosed embodiments; an exchangeable cartridge 10 containing a functional substance 12 (shown in Figure 3 only); a cartridge cap 9, which can be independent or fixed to the piston rod 8; a cartridge housing 2 that also provides housing for the advance member with a sliding groove 6 and a visible graded scale 7 (shown in Figure 2 only.); a piston rod 8 attached to the finger grip 5; a finger grip 5 having a shape that slidably engages with the internal bore of the housing 2 to maintain axial alignment of the piston rod and the finger grip; and finally a distal housing cover to keep the sliding components in place and facilitate manufacturing.
    In accordance with a further embodiment of the present invention, presented in Figure 4, there is a schematic drawing of a complete measured distribution device 14 incorporating an element capable of being manually rotated to drive a screw plunger. According to Figure 1, the assembly 14 comprises an element capable of manually rotating 15, a cartridge housing 16, a tip 17 of the extrusion conduit, and a proximal cover 18. As an additional detail, an exploded view presented Figure 5 shows the internal and external components of the assembly. The assembly consists first of an element capable of being manually rotated 15, which may include grip characteristics and textures; a helical spring 23 to provide pressure against the multilobed pin 22, a screw capable of advancing 20, a cartridge housing and the advancing member 16, an interchangeable cartridge 19 containing a functional substance (not shown), a tip 17 of the conduit extrusion, which may alternatively consist of several sections or elements in various previously disclosed embodiments; and finally a proximal cover 18 to cover the tip 17 of the extrusion conduit. In more detail, a cross-sectional view II of the device assembly 14 is illustrated in Figure 6. The assembly and several parts and features that first comprise an element capable of being manually rotated 15, which has on its exterior a surface is shown textured 24 to improve user interaction; a screw capable of advancing 20, in which the open inner region 25 of the element 15 represents the orientation where clearance is provided for the threaded region of the screw to pass through its center; a helical spring 23 in contact with a retaining feature of the element 15 and a distal face of the multilobed pin 22 to provide pressure of the protruding lobes 26 in the recessed lobes 27 of the cartridge / mechanism housing 16; a threaded hole 28 of the annular feature of the housing 16 to engage with the threaded section of the shaft 20 of the plunger; an exchangeable cartridge housing 19 retained in the housing 18 by a retention feature 28 of the housing 16; a cartridge cap 30, a functional substance 12, a tip 17 of the extrusion conduit having a fluid flow conduit 32; and finally a proximal cover 18. By providing more detail, shown in Figure 7, there is a partial detail view 33 of the sectional view II at a 90 degree axial rotation of the cross-sectional view II. Figure 7 illustrates in more detail a device assembly 14 and, in particular, shows the association of the two flat sides or of the advancing screws with the internal characteristics of the element capable of being manually rotated 15, which illustrates how the internal characteristics They are able to act on the screw and turn it.
    Figure 7 illustrates more details of the advancing member in which the assembly comprises an element capable of being manually rotated 15; a grip texture 24, an inner cavity 25 to allow the advance of the screw plunger 20, a spring retention feature 36 of the element 15; a spring groove 34 of the element 15; an annular extrusion 38 of the element 15 fixed in a groove 39 in the inner diameter of the perforation of the housing 16 of the mechanism, which serves to prevent the element 15 from leaving the housing 18, but also allowing its axial rotation; a sliding groove 36 of the element 15 to engage with and allow a space for the multi-lobed pin 22 to slide vertically during its rotation with the element 15; a hole 37 in the multi-lobed pin 22 for the free passage of the feed piston 20; a depressed lobe section 27 of an annular feature of the housing 18 for its interaction with the protruding lobes 26 of the multilobed pin 22; a threaded hole in the center of the annular feature of the housing 16; and, finally, an open chamber of the housing 16 for the free rotation of the advance piston 20. In more detail, in the depressed lobe characteristics of the annular section of the housing 16, Figure 8, there is a top view of the housing 16 illustrating four depressed lobes 27 and threaded hole 28. In addition, Figure 9 is an orthogonal side view of the multilobed pin 22, showing more detail of the pin, in which the pin includes four sections of protruding lobes 28; a central through hole 37, a square shaped section 41 to engage with the element 15 shown in Figures 4-7 to transfer the rotational movement to the pin; and a short annular section for alignment with the axially oriented helical spring 23 shown in Figures 5-7.
    As a further embodiment of the present invention using a mechanism capable of advancing from the stop block capable of advancing, Figure 10 is a schematic view of the device 43, consisting of a cartridge housing 46; a stopper housing 45 capable of advancing having a textured grip surface 47 to improve a user's ability to rotate the body; a distal end cover to provide the surface of the stop block for the distal end 44 of the depressable piston rod; a radially printed graduated scale 48 in the housing of the stop block 45 which coordinates with the graduated scale printed in the cartridge housing 49; and, finally, a proximal end cap 47 to cover an extrusion duct tip. In addition, in a similar, but alternative embodiment, Figure 11 depicts an embodiment 43 ′ having a groove 50 extending an axial length of the cartridge housing. Referring to Figure 12, a cross-sectional view III of the device 43 derived from Figure 10 is shown in more detail indicating the main features and interior elements. Continuing more details of the device 43 in Figure 12, the assembly first comprises a housing housing 46, which partially contains a housing 56 of the interchangeable cartridge containing a functional substance 12 and a plug 55; connected to the housing 48 at its proximal end is a tip 60 of the extrusion conduit with a fluid flow conduit channel 61 and the open end 62 that abuts the inner surface of the proximal cover 47 while also partially containing the proximal end of the casing 56 of the interchangeable cartridge and the functional substance 12 and is screwed itself 57 into the threaded end 58 of the housing 46; a housing 45 of the stop capable of advancing screwed in its interior to the housing 46 with threads 83; a distal stop block 52 installed in the housing 45 of the stop able to advance; and, finally, a depressible piston rod 43 with a distal end 44 aligned in channels provided by the stop block 52 and the piston retainer
    54
    Referring to Figure 13, a detail section 84 of Figure 12 is illustrated for further details of the device 43. Figure 13 illustrates in more detail the device 43 which first includes a cartridge housing 40 containing a cartridge interchangeable with the housing 58 abutting the proximal face of the piston retainer 64, and also containing the functional substance 12, and the cap 55; a housing 45 of the stopper capable of advancing which has threads 63 that engage with the threads 66 of the housing 46 and which has an annular groove 69 cut in a proximal groove of the threads 65 containing an o-ring to provide moderate resistance to helical rotation of the housing 45 of the stop capable of advancing as the O-ring passes through the outer surface of the housing 46; a piston retainer 54 having an inner groove 87 that retains an o-ring 68 to provide moderate resistance to the sliding movement of the rod 53 of the depressable piston; a piston retainer 54 having an outer groove 72 that retains a snap ring 71, whose snap ring is also retained in a groove 70 of the housing 48 that provides the function of locking the piston retainer 54 in its position in the housing 46; and, finally, a groove 74 trimmed at the proximal end of the rod 53 of the depressing piston that retains a pressurized ring 73 to prevent the rod from sliding out of the distal end of the piston retainer 54. As an additional detail, a view is provided exploded view of the device 43 in Figure 14 illustrating the details of device 43 described herein in an exploded view.
    In another additional embodiment of the present invention comprising an electronically operated feed member, Figure 15 is a proximal side view illustrating a device 75 consisting of a housing 76, a proximal cover 77, a button 80, a button 79 and an electronic display 78. As an alternative but similar embodiment, Figure 18 is a proximal side view of the device 75 'having an observation slot 81 of the cartridge. Figure 17 is a cross-sectional view IV of device 75 representing more details of device 75, which first comprises a housing 76 of the device, which houses both a cartridge and a feed member; a proximal lid 77 and a distal lid 81, both detachably retained; a tip 90 of the extrusion conduit having a fluid flow conduit 91 and an open end 82 that abuts the inner face of the proximal cover 77; a housing 89 of the interchangeable cartridge containing a functional substance 12 and the cap 88; a screw plunger capable of advancing 82 within a housing section 83 of the housing screw 76 of the device; and a user interface assembly comprising a button 80, a button 79, and an electronic display 78 in electrical communication with an electronic control circuit 85, which is also in electrical communication with an electric motor 86 through an extension 104 ( shown in Figures 18 and 19) and the battery 84 through an extension 103 (represented in Figure 18). In various embodiments, the flow of electric current can be achieved by an electrical element that contacts a battery cable through a connection, such as 103, and otherwise establishes a circuit establishing contact with the device housing, as well as It would be in electrical communication with the other battery cable. Also, in this and other embodiments, the battery can be interchangeable by removing a cover, such as cover 81, or it can be rechargeable and charged through externally accessible electrical cables in the housing or in an element associated therewith. .
    In addition, a detailed and sectional view 93 depicted in Figure 18 and an exploded view of the device 75 depicted in Figure 19 illustrate in greater detail the advancing member, which comprises the elements indicated in Figure
    17. In addition to an electrical communication port 104 extending from the electrical control circuit 85 which serves to connect the electrical control circuit 85 to the user interface features 80, 79, and 78; an electrical communication port 97 extending from the electrical control circuit 85 through a passage port 105 (shown in Figure 19) in the gear retaining unit 98 to the electric motor 86 retained in the housing slot 101 and having the rotational force transmission shaft 100 connected to the gear unit 99; a gear retainer unit 98 that retains intermediate gear 06, which is engaged with drive gear 99 and engaged with drive gear 95; an actuator gear 95 having a rectangular hollow section 102 at its axial center (shown in Figure 19) to provide a contact surface with the lead screw 82 having a two flat transverse surfaces and two partially threaded radial faces to engage with a threaded hole 87 of the housing 76.
    In a further embodiment of the present invention, a pneumatic feed member may be employed in the present invention and is illustrated in Figure 20 comprising a device 105 with a housing 107 of the device, a manual valve adjustment knob 110, a slot of observation of cartridge 106, and a proximal cover 109. In addition, Figure 21 represents a cross-sectional view V of device 105 illustrating the main interior components, including a housing 107 of the device, containing an interchangeable cartridge composed of the housing 108, functional substance 12, and plug 114; a tip 116 of the extrusion conduit with the threaded section 115 for coupling with the housing 107 of the device, which has a fluid flow channel 118 with a proximal open end that abuts a proximal inner surface of the lid retained detachably 117; a piston rod 113; a pneumatic cylinder 112; a valve body 110; a compressed gas cylinder 118 detachably retained in a housing slot 121. In addition, in a detailed and sectional view 122 depicted in Figure 22, an additional detail of the advancing member is illustrated which includes the features previously disclosed in Figures 20 and 21 in addition to more specific features, including a pneumatic cylinder piston 124 associated with the piston rod 113; a needle conduit 130 for establishing fluid communication of the pressurized gas of the pressure tank 119 with the valve assembly 110; a manual adjustment knob associated with the valve assembly to allow a user to adjust the flow and pressure configuration of the gas flow in the pneumatic cylinder; a depression 128 in the distal housing cover 111 to provide space for a depressive button 127; and an extended stem gas flow conduit 126 of the valve assembly 110 which directs the flow of gas from the pressure tank 119 to the pneumatic cylinder through a port 126 in the side wall of the pneumatic cylinder 122. In addition, An exploded view of the device 105 is depicted in Figure 23 illustrating the various features disclosed in Figures 20-22. In all embodiments, preferably, the compressed gas tank would preferably be interchangeable through a door in the housing, either on the side, at a proximal end, or from a distal end of the device housing.
    In a further embodiment of the present invention, a device assembly may comprise a cartridge housing capable of accommodating multiple cartridges. Figure 24 depicts a schematic distal view of an assembly 131 comprised of a multi-cartridge housing 138, which also has cartridge observation slots 133, a set of extrusion duct tips 132, a series of cartridge housing slots 134 , a matrix of cartridges 135, a channel for receiving a rotation shaft 140 from the advance member, an advance member 137, and a rod 138 of the piston capable of advancing. In addition, an exploded view of the assembly 131 is provided in Figure 25 comprising the details disclosed in Figure 24, in addition to a threaded section 141 of extrusion conduits 132 for connection to the cartridge housing 139; a piston rod 138 capable of advancing associated with a section 143 of the mechanism capable of advancing 137; a section 142 associated with the axis of rotation 140 for the controlled positioning of the mechanism capable of advancing, which is also associated with a passage 144 of the housing multiple cartridges 144.
    In all embodiments of the present invention disclosed herein, the extrusion duct tip may be composed of a single fluid flow channel, or it may be a cartridge retaining element composed of additional features or even composed of multiple sections that have different functional characteristics as previously disclosed.
    Referring to Figure 26, a cross-sectional view of an SSPCRE 145 having an SSPCRE body 146, a cartridge receiving section 148, a threaded section 147, a fluid flow conduit 151 with an open proximal end is shown 150, and one of characteristic heater element 149 placed in line with the fluid flow. In such an embodiment, the flow of functional substance would pass through or around the element in order to obtain thermal energy. In addition, the heating element would be in electrical communication with an electrical source (not shown) or could be an element capable of retaining a significant portion of heat for a useful period of time. Such an element could be heated by placing it in a microwave oven or heated by direct exposure to a heat source.
    In an alternative embodiment of SSPCRE 145 of Figure 26, element 149 may be a unidirectional valve body.
    In an alternative embodiment of SSPCRE 145 of Figure 26, element 149 may be a perforable septum from either a proximal or distal end.
    Referring to Figure 27, a cross-sectional view of a further embodiment 152 of an SSPCRE composed of a body 153, a cartridge receiving section 157, a threaded section 158, a fluid flow conduit 154 with a open proximal end 155, and a unidirectional duckbill-type valve 156 placed in line with the fluid flow. In such an embodiment, the flow of functional substance would only be allowed to flow from a distal end to a proximal end, but not vice versa.
    Referring to Figure 28, a cross-sectional view of an additional embodiment 159 of an SSPCRE composed of a body 180, a cartridge receiving section 185, a threaded section 163, a fluid flow conduit 161 with a open proximal end 162, and a distally oriented conical needle conduit 164 placed in line with the fluid flow. In such an embodiment, the flow of functional substance is only established once the needle section punctures a film or septum of a cartridge.
    Referring to Figure 29, a cross-sectional view of a further embodiment 186 of an MSPCRE composed of two bodies 187 and 171, a cartridge receiving section 175, a threaded section 174 of the body 171 for coupling with a housing is shown of cartridge, a threaded section 173 of body 171 for engagement with a threaded section 172 of body 167, a fluid flow conduit 168 with an open proximal end 169, and a unidirectional duckbill valve 156 associated with body 171 and placed in line with the fluid flow. In such an embodiment, the flow of functional substance would only be allowed to flow from a distal end to a proximal end, but not vice versa. In addition, body 167 would be able to detach detachably in body 171 and allow a user to easily exchange body 167 without exposing the cartridge to atmospheric gases,
    Referring to Figure 30, a cross-sectional view of an additional embodiment 178 of an MSPCRE composed of two bodies 177 and 180, a cartridge receiving section 184, a threaded section 183 of the body 180 for engaging with a housing of is shown. cartridge, a threaded section 182 of the body 160 for engagement with a threaded section 181 of the body 177, a fluid flow conduit 178 with an open proximal end 178, and a distally oriented conical needle conduit 185 placed in line with the flow of fluid. In such an embodiment, the flow of functional substance is only established once the needle section punctures a film or septum of a cartridge. In addition, the body 177 would be able to be detachably retained in the body 180 and would allow a user to easily exchange the body 167 without exposing the cartridge to
    significant portions of atmospheric gases.
    Referring to Figure 31, a cross-sectional view of an embodiment 186 of an interchangeable cartridge composed of a cartridge housing 139, a functional substance 12, a plunger cap 188, a distal sealed seal film 187, and a bonded proximal seal film
    190. In addition, films 190 and 187 may be heat sealed films, adhesive bonded films, elastomeric septa, or other analogous films that are fixed to the distant ends of the cartridge housing 189 and which could preferably be separated by a user.
    Referring to Figure 32, a cross-sectional view of an embodiment 191 of an interchangeable cartridge composed of a cartridge housing 193 with an open distal end, a functional substance 12, a plunger cap 192, and an end cap is shown. proximal inserted by compression 194. In such an embodiment, the end cap 184 can be removed before use of the cartridge or can be pierced by a septum to establish fluid communication with the functional substance 12. In such an embodiment, preferably the piston plug 192 would establish a seal with the bore of the internal diameter of the housing sufficient to prevent the flow of atmospheric gas.
    Referring to Figure 33, a cross-sectional view of an embodiment 195 of an interchangeable cartridge is shown comprising in a cartridge housing 197, a functional substance 12, an adhered distal sealing film 196, and a proximal sealing film adhered 198. In addition, films 196 and 198 may be heat sealed films, adhesive bonded films, elastomeric septa, or other analogous films that are fixed to the distant ends of the cartridge casing 197 and which could preferably be separated by a user. In such an embodiment, the cartridge lacks a plunger plug that would otherwise be installed in a piston rod associated with a feed member.
    Referring to Figure 34, a cross-sectional view of an embodiment 199 of an interchangeable cartridge comprising a cartridge housing 201, a functional substance 12, a distal end cap inserted by compression 200, and a proximal end cap inserted is depicted. by compression 202. In such an embodiment, the end caps 200 and 202 can be removed before use of the cartridge or can be pierced by a septum to establish fluid communication with the functional substance 12.
    Referring to Figure 35, a cross-sectional view of an embodiment 203 of an interchangeable cartridge comprising a cartridge housing 205, a functional substance 12, a proximal terminal plug inserted by compression 206, and a plunger plug which is shown is shown. It has a feed rod associated with it that can be inserted into a feed member. In such an embodiment, the end cap 208 can be removed before use of the cartridge or can be pierced by a septum to establish fluid communication with functional substance 12.
    Referring to Figure 36, a schematic side view of an embodiment 207 of an interchangeable cartridge is shown consisting of a cartridge 208 having a film 208 with a tongue attached to the proximal end of the cartridge housing. In such an embodiment, the tongue would facilitate a user from manual removal of the film. In all of the foregoing disclosed embodiments, in which a film seal is incorporated, those films may also alternatively include a tab as disclosed herein.
    memory.
    Referring to Figure 37, a schematic side view of an embodiment 210 of an interchangeable cartridge is shown consisting of a cartridge housing 212 having a groove that passes down its transverse length, in which various embodiments can be incorporated. in cartridges to provide them with a key slot to fit into the specific cartridge housing that has a matching key. Alternatively, the key slot shown here may alternatively be an outgoing key that would serve the same function, but would simply stand out instead of being lowered.
    Referring to Figure 38, a set of multiple devices 213 is presented in which a connection element 214 connects two devices of the present invention 43 to an identical device 43. Alternatively, two non-identical devices of the present invention can be connected together in a similar way,
    Referring to Figure 39, a Figure is presented in order to illustrate an exemplary process of the action that the present invention would support during its use; a device 43 is presented in which the arrows representing the physical force at its distal end are transferred downwards in a cartridge and, consequently, the force is exerted on the functional substance 12, forcing it to extrude through the tip of the Extrusion duct and deposit outside the device (observed as 12 ') on a physical surface 215.
    Referring to Figure 40, a detail of a cross-sectional view of an assembly of the cartridge housing 217 and the tip 219 of the extrusion conduit in which a heating band 216 is represented as a heating band is shown. surrounds the cartridge housing 217 that functions to heat the functional substance 12. In such an embodiment, the heating band can accept communication and electrical power from an external source or can receive communication and electrical power from an onboard element. In alternative embodiments, the heating band 216 may be integrated in the housing 217 or may be manually separated. In an alternative embodiment, the heating band can provide heat through a chemical process or be heated first by an external source and provide an amount of heat to the interior components for a later time.
    Referring to Figure 41, a cross-sectional cross-sectional view of an embodiment of an interchangeable cartridge casing having a main casing section 220, a conical casing section 221, and an open end 222 is shown. In an embodiment of In this type, the cartridge itself may contain a functional substance and, in addition, provide a reduced section to directly extrude the functional substance without the need for an additional extrusion duct tip.
    Referring to Figure 42, a cross-sectional cross-sectional view of an embodiment of a cartridge 223 having an integral cartridge retainer 225 is shown; which is represented with threads; a cartridge housing 224; a tip section 226 of the conical integral extrusion conduit; and a flow channel 227 of the extrusion conduit.
    Referring to Figure 43, a perspective view is shown from the proximal end of an embodiment of a cartridge 228, which consists of a cartridge housing 229, a transverse slit resistive valve 230 fixed to the proximal end of the cartridge housing. which has slits 231.
    While the invention has been described with respect to certain embodiments, as will be appreciated by those skilled in the art, it should be understood that the invention is capable of numerous changes, modifications and rearrangements, and such changes, modifications and rearrangements are intended to be covered by the following claims.
    权利要求:
    Claims (9)
    [1]
    1. A device for distributing a measured amount of a functional substance, the device comprising:
    a cartridge housing having a proximal end, a distal end and an internal perforation, the cartridge housing being configured to accommodate an interchangeable cartridge that includes a cartridge cap and a functional substance;
    an extrusion conduit tip at the proximal end of the cartridge housing, the upper part comprising a fluid flow conduit; Y
    a feed member configured to fit the internal perforation and configured to move axially through the perforation;
    characterized in that the device further comprises
    a multilobed pin and a helical spring configured to provide pressure against the multilobed pin;
    wherein, when the advancing member moves towards the proximal end of the housing, it pushes a measured amount of the functional substance through the tip of the extrusion duct;
    and wherein a manual handling member comprises elements capable of being manually rotated, configured to advance a plunger through the internal bore when it is rotated.
    [2]
    2. A device for distributing a measured amount of a substance
    functional, characterized by the device comprising:
    a housing having a proximal end, a distal end and an internal perforation, the housing being configured to contain a functional substance;
    a feed member configured to fit the internal perforation and configured to move axially through the perforation; Y
    a stop capable of advancing configured to move axially with respect to the housing and blocking the movement of the advancing member through the internal perforation, based on the position of the stop capable of advancing in relation to the housing; Y
    wherein, when the advancing member moves towards the proximal end of the housing, it pushes a measured amount of the functional substance out of the proximal end, the measured amount being determined by the position of the stop capable of advancing with respect to the housing;
    wherein the stop capable of advancing comprises a helical thread configured to engage with a helical thread in the housing, and whereby the rotation of the stop capable of advancing causes the stop capable of advancing to move axially with respect to the housing;
    where the accommodation comprises a first graduated scale:
    wherein a 360 degree rotation of the stopper capable of advancing causes the stopper capable of advancing to move axially with respect to the cartridge housing a distance of one unit on the first graduated scale;
    where the stop capable of advancing comprises a second graduated scale;
    where the second graduated scale is located
    circumferentially around the stop able to advance;
    wherein the second graduated scale comprises fractions of the first graduated scale, so that a partial turn of the stop capable of advancing indicates a fractional advance of the stop capable of advancing with respect to the first graduated scale.
    [3]
    3. The device of claim 2, characterized in that it further comprises a second cartridge housing substantially similar to the first cartridge housing, wherein each cartridge housing is configured to accommodate an interchangeable cartridge and allow independent distribution of functional substances of its interior;
    in which the functional substances of the interchangeable cartridge are mixed before their expulsion through the tip of the extrusion duct;
    wherein the advance member is in electrical communication with an electronic control circuit and an electric motor;
    in which the advance member is configured to be electronically controlled; Y
    in which the advance member can be controlled by a remote operator; Y
    where the device is configured to supply a quantity
    measurement of one or more functional substances, the quantity being predetermined by the remote operator.
    [4]
    4. A method of distributing a measured amount of a substance
    functional, characterized by the method by which it comprises: providing a device for distributing a measured amount of a
    functional substance, the device comprising:
    at least one cartridge housing comprising a
    internal perforation;
    a forward member; Y
    a stop capable of advancing; and
    insert at least one or two interchangeable cartridges containing a functional substance into the device;
    move the advancing member a measured distance through the internal perforation, thereby pushing a dosed amount of functional substance out of the device.
    [5]
    5. The method of claim 4, characterized in that the plunger is advanced manually.
    [6]
    6. The method of claim 4, characterized in that the plunger is advanced electronically.
    [7]
    7. The method of claim 4, characterized in that the plunger is advanced by the pressure provided by a pneumatic system.
    [8]
    8. The method of claim 4, characterized in that the measured distance is defined by a visible graduated scale.
    [9]
    9. The method of claim 4, characterized in that it further comprises adjusting the stop capable of advancing to a position with respect to the advancing member, wherein the stop capable of advancing limits the amplitude of
    movement of the advancing member, thereby limiting the amount of functional substance expelled from the device.
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    同族专利:
    公开号 | 公开日
    CA2964457A1|2016-04-21|
    JP6507237B2|2019-04-24|
    RU2685686C2|2019-04-22|
    CZ2017259A3|2017-08-30|
    IL251660A|2020-05-31|
    RU2017112763A3|2018-11-15|
    AU2015333703B2|2018-12-13|
    RU2017112763A|2018-11-15|
    ES2638007R1|2017-11-06|
    GB201707675D0|2017-06-28|
    WO2016061062A1|2016-04-21|
    GB2547831A|2017-08-30|
    AU2015333703A1|2017-04-27|
    IL251660D0|2017-06-29|
    JP2017531499A|2017-10-26|
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    法律状态:
    2019-04-12| FC2A| Grant refused|Effective date: 20190408 |
    优先权:
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    US201462063198P| true| 2014-10-13|2014-10-13|
    US62/063,198|2014-10-13|
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