专利摘要:
The current invention relates to an adjustable mandibular advancement device with a unique combination of resilient hinging, dentition engagement and adjustability, to prevent or reduce Snoring and/or Obstructive Sleep Apnea Syndrome. The device is made of an upper member to engage the maxillary dentition and a lower member to engage with the mandibular dentition, the members connected by a resilient hinge with embedded adjustability. The adjustability is described by means of a concept of adjustability for the relative enlargement or diminution of the members of the device by a set of successive advancement mechanisms, in either combination or separately. By use of a thermoplastic material the device can be used in the outmost variability of the human dentition.
公开号:DK201400149A1
申请号:DK201400149
申请日:2014-03-17
公开日:2014-12-15
发明作者:Natashia Ingemarsson Matzen
申请人:Natashia Ingemarsson Matzen;
IPC主号:
专利说明:

SUCCESSIVE ADJUSTABLE MANDIBULAR ADVANCEMENT DEVICE FOR PREVENTING AND TREATMENT OF SNORING AND OBSTRUCTIVE SLEEP APNEA.
Abstract
The present invention relates to an adjustable mandibular advancement device with a unique combination of resilient hinging, dentition engagement and adjustability, to prevent or reduce Snoring and / or Obstructive Sleep Apnea Syndrome. The device is made of an upper member to engage the maxillary dentition and a lower member to engage the mandibular dentition, the members connected by a resilient hinge with embedded adjustability. The adjustability is described by means of a concept of adjustability for the relative enlargement or diminution of the members of the device by a set of successive advancement mechanisms, in either combination or separately. By using a thermoplastic material the device can be used in the outmost variability of the human dentition.
Field of invention
The present invention relates to an adjustable mandibular advancement device which, by virtue of a successive (continuous) mechanism, advances the mandibular relative to the maxilla in order to prevent or reduce Snoring and / or Obstructive Sleep Apnea Syndrome (OSAS) during sleep. The adjustability is accomplished by the intrinsic embedded mechanism of the two members in conjunction or separately in either of the members relative to the other.
Background of the invention
Snoring and Obstructive Sleep Apnea are generally known today as the same disease on a continuum of the sleep disorder severity scale. Starting at the modest degree of snoring ending in the fulminate obstructive sleep apnea condition is known as a fact.
As the disease is closely related to a wide variety of physical and mental conditions, treatment is of paramount importance as soon as possible.
According to the snoring condition is characterized by the sounds developed by vibrating tissues in the most dorsal area of the pharynx, either the nasopharynx, or the oropharynx or the laryngopharynx, the obstructive sleep apnea is characterized by actual respiration arrest caused by occlusion of the pharyngeal airways .
Apnea appears when the upper airway passages are being sucked close to the back of the throat when the person is trying to breathe during sleep. The occlusion may be the result of suction or by the lapse of tone in the oral soft tissues during the relaxed sleep condition.
When the occlusion is there, no air is passing through the pharynx and down to the lungs, and this is the situation called OSAS (Obstructive Sleep Apnea Syndrome).
The obstruction can happen as often as 1000 times during the night time sleep in which the body is deprived of oxygen uptake from the air into the blood stream, which eventually leads to the aggravated symptoms.
The severity of OSAS has been described in the medical literature numerous times causing a number of symptoms and diseases:
General headache High blood pressure Diabetes
Hypoxic pulmonary vasoconstriction cardiomyopathy
Pulmonary hypertonia with cor pulmonale (increased pressure in the heart-lung circuits)
Heart failure, heart arrhythmia, heart attack Day time melancholy or depression Intelligence alterations
Acid Reflux (GERD - Gastro Esophageal Reflux Disease)
Potency disturbances
Worsening of ADHD (Attention Deficit Hyperactivity Disorder), in addition to a large number of problems of a more social character, such as, e.g., divorce, decreased labor activity, difficulties in keeping conversations in the track due to tiredness, etc.
Thus, compared to a normal control group without diseases, patients suffering from snoring and / or OSAS appear to have: three times as many cases of coronary heart disease, four times as many cerebral diseases, such as clots, twelve times as many incidents of car accidents and twice as many labor accidents due to day time sleepiness as a result of lack of sleep and / or impaired sleep quality.
Due to these conditions, life time expectancy is severely limited for these patients, and their quality of life is compromised.
The continuum of snoring diseases gives the following frequency figures: ► 40% of adults over 40 snore (approx. 87 million Americans) ► 9% of men and 4% of women suffer from some form of OSAS (approx. 30 million Americans) ► Less than 10% of OSA sufferers have been diagnosed (Approx 3 million Americans) ► Of those, less than 25% have been successfully treated.
For the above reasons, it is important to provide devices to eliminate and prevent apnea and the incipient stages thereof.
In the prior art, a number of surgical techniques for the removal of the tissue involved in the obstruction have been developed, but all of these techniques seem to incur a certain disability of the patient and, at the same time, do not have a fully predictable effect.
Furthermore, a number of medical treatments have been tried out with predominantly deficient or sometimes even damaging effect.
Finally, the scientific literature and the patent literature disclose numerous devices for alerting the snoring patient during sleep; devices for tongue thrust, devices for forward movement of the soft palate; devices for obstructing the oral cavity (delimited by the lips), thereby engaging the sound from the snoring; furthermore, mandibular advancement splints or appliances, mouth guard-like devices for provocation of either tongue, hyoid bone or jaw position changes, thereby eliminating snoring; - all of these requiring active participation from competent professionals, such as medical doctors, dentists, etc. Among such prior art devices for or attempts to inhibit snoring, the following are of particular interest in the present context: EP 0 794 749 B1 (Ingemarsson -Matzen & Voss) discloses a jaw position-regulating oral device for preventing snoring and obstructive sleep apnea during sleep. The device consist of two members, a first member to engage with the maxillary dentition and a second member to engage with the mandibular dentition, both connected by a resilient hinge. The mechanism is embedded in the mandibular advancement relative to the maxilla. The main difference from the present patent application is the lack of adjustability of the members length relative to each other. WO 2013/032 884 A1 (Fallon & Jung) discloses a mandibular advancement device with an upper and lower member to engage the maxillary and mandibulary dentition, respectively. The lower tray assembly is mated to and slidably adjustable by the patient relative to the upper tray assembly. The main difference from the present patent application is that the device lacks a resilient hinge. WO 2009/062 541 A1 (Magning & Magnin) discloses a mandibular advancement orthosis in which the device comprises a unitary flexible member that can be folded on itself for interaction with the teeth of the upper and lower arches, and an interchangeable flexible strip for surrounding the teeth of the upper arch, having a length that can be modified in order to obtain the desired level of mandibular advancement. The main difference from the present patent application is that the device is regulated by detachable flexible strips and not intrinsic in the device itself. US 2009/0014 013 A1 (Magnin) discloses a mandibular advancement splint made of two thermoformable trays designed to envelope the upper and lower arch. The advancement splint includes an articulated frame having rigid and flexible elements immersed in the thermoformable flexible material or molded around it. The main difference from the present patent application is that the device is made by two separate members without any hinge. EP 1 719 481 A1 (Arni) discloses a mandibular advancement device with a lateral link incorporated into a mandibular protrusion device comprising an upper dental tray and a lower dental tray so as to advance or retract the lower dental arch during a vertical movement between the two . The link is adapted to be accommodated in an opening of a ball pivot. The main difference from the present patent application is that the device lacks the intrinsic resilient. EP 2 529 710 A1 (Ash) discloses a device for mandibular advancement in which an upper member and a lower member are interconnected by means of pivotable connection in which at least one is formed as a stud. The main difference from the present patent application is that the device is made of two separate members with detachable attachment cylinders and clamps attached to the outside of the members. CA 223 650 3 Al (Frantz & Frantz) discloses a mandibular advancement device which uses elastic bands to pull the jaw forward. The upper part having a set of retention hooks and the lower part having a set of interchangeable slide-in posterior occlusal bite planes. The main difference from the present patent application is that the device is the use of detachable elastic bands and no intrinsic resilience in any hinge. WO 2008/130 413 A1 (Meade) discloses a mandibular advancement device for pulling the lower jaw forward composed of an upper and a lower member to engage the dentition, where a ball type of hook support is located on both sides of the upper tray at a forward position and a ball type of hook supports are located at a rearward position of both sides of the lower jaw. A tension coil is attached to each of the upper and lower ball type of hook supports. The main difference from the present patent application is that the device uses detachable hooks and spring coils and lacks the resilient hinge mechanism. US 2013/001 4765 A1 (Meade) discloses a mandibular advancement device for pulling the lower jaw forward composed of an upper and a lower member to engage the dentition, where a ball type of hook support is located on both sides of the upper tray at a forward position and a ball type of hook supports are located at a rearward position of both sides of the lower jaw. A tension coil is attached to each of the upper and lower ball type of hook supports. The main difference from the present patent application is that the device uses detachable hooks and spring coils and lacks the resilient hinge mechanism. WO 2011/115 962 A1 (Van Dyke & Tucker) discloses a mandibular advancement splint made of two trays designed to envelope the upper and lower arch. The upper appliance has a pair of adjustable wings attached to the body, and the lower has a pair of fixed wings attached to the body. The upper wings are slidable adjustable. The main difference from the present patent application is that the device is made of two separate members without any hinge and that uses detachable pivots in both upper and lower members. US 2010/004 380 5 A1 (Kelly) discloses a mandibular advancement device with an upper and lower member to engage with the dentition of the human. The lower dental plate having two pairs of spaced apart pillars and two removable attachable horizontal displacements inserts on the upper part. The main difference from the present patent application is that the device uses detachable vertical displacement inserts and lacks the resilient hinge mechanism. GB 2 264 868 A (Mateljan) discloses an anti-snoring device for oral use, comprising members having upper and lower surfaces which engage the user's maxillary and mandibular dental arches, respectively. The upper and lower surfaces are spaced so that the mandible is placed in a forwardly offset position relative to its normal position. The spacing also tensions the masticatory muscles to maintain the device in place. The main difference from the present patent application is that the device has no capability of adjustability in antero-posterior directions, and no hinge in the back of the device. US 2011/001 722 0 A1 (Lindsay et al.) Discloses a self-titratable mandibular repositioning device that allows for adjusting the maintained forward position by simply biting-down to preserve the desired degree of mandibular advancement, made of a lower and an upper member to engage the dentition. The main difference from the present patent application is that the device has no resiliency of any hinge. US 2008 / Oil 579 1 Al (Heine) discloses a mandibular advancement device with an intraocclusal removable device in the form of a "U" that is placed covering all of the upper jaw teeth, two steps, one in each extreme of the lower part of the element which impedes the mandible is completely closed to its normal occlusion, forcing it to produce a forward displacement of the lower jaw. The main difference from the present patent application is that the device is that this device is a one member device with no hinge and only minor protrusive force can be applied to the lower jaw and only in occlusion. US 2005/023 600 3 Al (Meader) discloses a mandibular advancement device as a single piece of molded plastic with said unit modeled from four theoretical positions including a shield like anterior portion fitted and anchored between anterior teeth-gums and behind the lips. The main difference from the present patent application is that the device is a mono-block decided for prevention of lip closure. US 2010/030 045 8 Al (Stubbs et al.) Discloses a mandibular advancement device with an upper and lower member to engage with the dentition of the human. The members include a cam associated with one of the jaws and a follower associated with the other jaw. The main difference from the present patent application is that the device is the lack of hinge in the posterior part. US 2008/009 902 9 Al (Lamberg) discloses a mandibular advancement device composed of a maxillary main body for removable attachment to the maxillary teeth with a protrusive element extending from the central portion of the body and a mandibular removable appliance attached to the mandibular anterior teeth. The main difference from the present patent application is that the device has a forcing mechanism on the lower jaw and lacks the posterior hinge. EP 2 491 901 A1 (Garcia Urbano) discloses regulated intraoral mandibular advancement device for preventing snoring and sleep apnea in which a screw system is located in the central part of the connection between the upper and lower members for the involvement of the dentition. The main difference from the present patent application is that the device is operated by a non-intrinsic screw and screwdriver to maintain the regulated forward position of the mandible relative to the maxilla. AU 1999 476 15 B2 (Palmisano) discloses a mandibular advancement device in which the upper jaw is firmly fitted into an upper plate and the lower jaw is firmly fitted into a lower plate, these two parts being connected by means of opposing flange components located to be located in an area and close to the posterior teeth. The main difference from the present patent application is that the device is constructed with a pivotable mechanism and not a hinge. US 2013/001 476 5 A1 discloses a tongue and mandibular advancement device in which an upper member has hook supports anteriorly and a lower member has a plurality of hook support at the rearward position. The main difference from the present patent application is that the device separates the two member system without any intrinsic hinge. EP 0 337 201 discloses an orthodontic appliance comprising a first member to engage with the mandibular dentition and a second member to engage with the maxillary dentition. The two members are resiliently hinged together to keep the upper and lower jaw in a normal position. The main difference from the present patent application is that the device is the lack of adjustability in the sagital plane, thereby delimitating the usability as a snoring prevention device. WO 92/11827 discloses an anti-snoring device for oral use consisting of a horseshoe-like upper jaw member for engaging the maxillary dentition, with the downward extending flange intended to extend into the lingual vestibule in order to maintain a forward posture of the lower jaw. The main difference from the present patent application is that the device is using a forcing mechanism on the lower jaw. EP O 312 368 discloses an anti-snoring device for oral use which resembles the device mentioned above, the main difference being the design of the airway passage. The main difference from the present patent application is that the device is using a forcing mechanism on the lower jaw. WO 92/05752 (Wu) discloses an anti-snoring device for oral use consisting of a spatial member congruent with the palate and a lower member adapted to the lingual aspects of the surfaces of the dentition in the lower jaw, hooks being attached to the occlusive plane of the device for fixing the two jaws in a predetermined relation. The main difference from the present patent application is that the device is using detachable elastics and has no resilient hinge. US 5,313,960 (Tomasi) discloses an anti-snoring device for oral use consisting of two horseshoe-like individually shaped mouthpiece portions which are connected and fixed in a predetermined position in which the lower jaw protrudes in relation to the upper jaw. The main difference from the present patent application is that the device is using a predetermined forward position of the lower jaw relative to the upper jaw, and there is no resilient hinge. US 7,910,502 B1 (Nguyen & Nguyen) discloses an anti-snoring device for oral use consisting of two horseshoe-like individually shaped mouthpiece portions which are connected and fixed by an assembly of tubes, hooks and screws to be attached to the two separate members. The main difference from the present patent application is that the device is using detachable screws, spring coils and loops to keep the mandible in a forward position, meaning that there is no intrinsic resilient hinge. Therefore, the device is much more complicated and technical demand, with an additional disadvantage of plaque accumulation and deteriorated hygiene to follow. DE 201 02 432 U1 (Trentepohl et al.) Discloses an anti-snoring device for the oral use comprising an upper and lower member engaging with the maxillary and mandibulary dentition interconnected by an adjustable telescopic device attached to the outer surface of the members. The main difference from the present patent application is that the device is using detachable telescopic devices to keep the mandible in a forward position. Thus the device lacks the intrinsic resilient hinge. Also, the device is much more complicated and technical demanding, with an additional disadvantage of plaque accumulation and deteriorated hygiene to follow. WO 21013 049 751 A2 (Rogers) discloses a method for use in connection with sleep-disordered breathing, of forming oral orthotic systems to position and / or stabilizing a mandible of a patient, including providing an upper dental member adapted to be placed in connection with upper dentition of the patient, providing a lower dental member adapted to be placed in connection with lower dentition of the patient providing a plurality of posterior mounting structures. Each of the posterior mounting structures is adapted to be attached to one of the upper dental member or the lower dental member at a posterior, buccal position thereon. Each of the posterior mounting structures includes a plurality of positions at which one of the pluralities of connectors is attachable to the extending member. Force may be applied to the mandible of the patient via at least one of a plurality of different mechanisms via attachment of a component of the mechanism to at least one of the posterior mounting structures. The upper dental member and the lower dental member are formed independently from at least one polymeric material. The main difference from the present patent application is that the device is using multiple detachable mounting structures to keep the mandible in a forward position. Thus the device lacks the intrinsic resilient hinge. The upper and lower members are constructed after direct impressions of the user's teeth, and then separately in a second laboratory procedure the hard polymeric (acrylic) material casts to form congruent trays for the upper and lower jaws. If this system is using hard acrylic material it is substantially different from the present patent application in function, durability and comfort. This gives a disadvantage in terms of monetary price for the end user. Also, the device is much more complicated and technical demanding, with an additional disadvantage of plaque accumulation and deteriorated hygiene to follow. US 2013 009 837 2A1 (Webster et al.) Discloses an oral appliance for prevention of sleeping problems, including snoring, sleep apnea and bruxism. Specifically, the device alters the position of the mandible and is made of a one piece device molded from a flexible polymer. Both upper and lower dental trays include inner and outer walls which increase contact area with the teeth. The hinge mechanism of the device includes a positive positioning system comprised of upper and lower opposed interlocking ridges. The ridges serve to create offset between the position of the upper and lower tray relative to each other, therefore advancing the user's mandible. The main difference from the present patent application is that the device is a one-piece device folded at a fixed point in the back most posterior part of the device to keep the mandible in a forward position. The interlocking ridges keep the lower and upper trays in a fixed forward position, thereby simply prohibiting the other vice rolling possibility of the device leading to misuse of the intention of the device. So there is no kind of incremental or successive adjustability. Hence there is no individualization possibility. US 2011 022 626 1A1 (Hernandez) discloses a mouthpiece for reducing snoring. The mouthpiece includes an upper guard configured to fit over the user's upper teeth, a lower guard configured to fit over a user's lower teeth, a spacer assembly provided between the upper guard or the lower guard to provide an air passage at the middle section of the mouthpiece, a first adjustable assembly attached to the left side of the upper guard and the left side of the lower guard, and a second adjustable assembly attached to the right side of the upper guard and the right side of the lower guard . The first adjustable assembly and the second adjustable assembly are operable to move the lower guard relative to the upper guard. The main difference from the present patent application is that the device is using detachable blocks and screws devices to keep the mandible in a forward position. Although the device depicts a kind of hinge (flexible coplanar connectors), this hinge is merely decided to avoid sharp edges on the posterior part of the two members and for ease and economy of manufacture, and cannot function as an actual durable active hinge due to the fact that the screws in the blocks are rigid. In conclusion, the device is much more complicated and technical demand, with an additional disadvantage of plaque accumulation and deteriorated hygiene to follow. WO 01 302 60 Al (Bergersen) discloses a patent application as an intra-oral appliance for repositioning the user's mandible anterior to the user's maxillary teeth, thus opening the user's oral, pharyngeal passageway preventing snoring and sleep apnea. The appliance is two U-shaped plates joined to form a hinge. The lower plate has lingual tabs which are employed to help position the appliance. The main difference from the present patent application is that the device is completely lacking any kind of incrementally and / or successively adjustability. Also the WO 01 302 60 A1 is merely a transcription of the original patent EP 0 794 749 B1 (Ingemarsson-Matzen & Voss) except the lingual tabs which in the original version is a solid moldable block.
Disclosure of the Invention
While the above devices represent attempts to solve the snoring and apnea problems, they are all rather complicated in their design and most of these require the interaction of a professional team in their individual design. Furthermore, they are rather discomfortable to the wearer, and they do not appear convincing with respect to their ability to achieve an effective and long-lasting anti-snoring effect.
Thus, there is a demand for a relatively comfortable device which provides a high degree of inhibitory effect on snoring during even long sleeping periods, such as overnight, without adverse effects on the structures involved, and which at the same time is easy and simple to use and wear for normal non-skilled persons.
The present invention provides such a device.
The adjustable anti-snore device according to the invention comprises an upper member adapted to engage the maxillary dentition of a human and a lower member adapted to engage the mandibular dentition of the human, the upper and lower members being resiliently or mechanically hinged together, The resiliency of the hing is adapted to allow the physiological movement of the lower jaw into the sagital plane while retaining a forward position of the lower jaw relative to the upper jaw and thereby maintaining the airway passage in the nasopharynx, the oropharynx and the hypopharynx substantially. free of occlusion, while at the same time embody the adjustability in the form of a successive mechanism.
The device according to the invention combines three essential functions: the forward positioning of the lower jaw relative to the upper jaw, the hinging, and the adjustability of the sagital relation between the two members. As will be explained below, the forward positioning of the lower jaw is essential to prevent occlusion of the airway passage in the pharyngeal space during sleep. The resilient or mechanically hinged makes it possible and realistic to maintain the forward position of the lower jaw even during movements in the sagital plane which inevitably occur during sleep. And the adjustability makes it useful for even the smallest and largest person wearing the device. This essential combination of features which ensures constant non-constricted airflow and unrestricted movement in the sagital plane and thereby ensures a constant efficient function without risk of the device falling out of the user's mouth and without any substantial discomfort together with the adjustability which also allows some horizontal movements, distinguishes the device according to the invention from all of the abovementioned prior art devices.
The device according to the invention may be made of any material, such as metal, alloy, wood, plastics, etc. provided that the device made feels soft and comfortable in the mouth without any constriction or damaging of the tissue, such as gums, tongue, teeth, but at the same time is sufficiently capable of retaining its shape and of exerting sufficient resiliency towards the muscular tension and forces acted upon the jaws so that it will maintain the lower jaw in the anterior position while allowing normal movements during sleep . The material used for the device according to the invention should not contain any allergens or other kind of toxic ingredients.
The device according to the invention is preferably made of a resilient non-toxic plastic material, such as a polyvinyl resin, including a vinyl acetate-ethylene copolymer such as poly (ethyl vinyl acetate), or a polyolefin such as polyethylene or polypropylene.
It is particularly preferred that the resilient non-toxic plastics material is a thermoplastic material, such as a cellulose derivative, a vinyl polymer, a polystyrene, a polyamide, an acrylic resin, etc., which can be shaped to adapt to an individual dentition at moderate heating, such as heating to a temperature above normal human body temperature, that is, a temperature of at least 40 ° C and at most 80 ° C, e.g. about 70 ° C. The material presently most preferred by the inventor is ethylene vinyl acetate copolymer.
The device according to the present invention may be manufactured by plastic molding, such as cold molding, compression molding, injection molding, etc. The manufacturing method presently most preferred by the inventor is injection molding.
The upper and lower members are preferably integrated with each other through resilient hinges made of the same material as the upper and lower members. However, the hinges may be reinforced and their resiliency enhanced by insertion, such as cast in, etc., into the hinges of a resilient member, such as a resilient plastic member, a metallic resilient member, such as a flat spring, a laminated spring etc. etc., or simply by a mechanical connection.
The adjustability according to this invention, being embedded or glued, gilded or otherwise attached to the members of the dentition engagement, in the upper maxillary member, the lower mandibulary member or both members at the same time, being either incremental or successive is a major novelty and is unique to this device.
As will be understood the adjustability is embedded in the anterior parts of the upper and / or lower members of the device thus keeping the posterior resilient or mechanical hinge intact.
The adjustability of the protrusion of the mandible relative to the maxilla is made adjustable by the means of embedding a positive structure in either the forward moving part or the device and a negative structure in the stable part of the device or vice versa. The positive part may be constructed as a rod or alike, whereas the corresponding negative structures would be cylinders and alike in this aspect. Other configurations may apply. Thus the adjustability will express itself as a successive (stepless) adjustability.
When the successive design is used, a special rod can be supported for the consumer which allows fixation of the desired position of the forwarded device. Said special rod and alike may be made of a heat conducting metal insulated with a non-heat conducting hand piece, so as not to damage the fingertips of the user when heating the rod and penetrating the material of the invention at the desired position. A particularly preferred way of shipping the device according to the invention to the end consumer is as a kit comprising the device and a temperature indicator adapted to indicate a temperature change to an elevated temperature at which the material of the device can be shaped. This makes it simple and safe for the end user to mold the device in accordance with his or her specific dentition simply by heating the relevant domain of the device in water at the temperature of which is kept in the correct temperature range for the material in question. by using the indication of the temperature indicator.
It should be understood that the use of the anti-snore device according to the invention is not limited to prevention or reduction of snoring or OSAS but the device is applicable in any situation where it is desirable to secure free airway passage in human beings, such as during recovery from anesthesia, during unconsciousness, etc.
The unique combination of posterior resilient / mechanical hinging, dentition engagement and adjustability discussed above can also, according to another aspect of the invention, be utilized in a device for relieving guided transpositions of the jaws.
In this latter aspect, the invention relates to an orthognatic function device comprising an upper member adapted to engage with the maxillary dentition of a human and a lower member adapted to engage with the mandibular dentition of the human, the upper and lower members having bases which prevent direct contact between opposing teeth, thereby eliminating guided transposition of the jaw relation and the upper and lower members being resiliently hinged together in such a manner together with the adjustability that the lower jaw of the human is kept positioned in a normal position relative to the upper jaw, allowing vertical movement and, in the occluded intercuspidal position, allowing horizontal movement so that the temporo mandibular joint is kept substantially in its resting position, both when the lower jaw is at rest and when it is working.
It will be understood that also in this aspect, the resiliency of the hinging should be adapted to allow the physiological movement of the lower jaw in the sagital plane, and that the above comments regarding selection of suitable materials, manufacturing method, and adaptation to the individual dentition by shaping the material in a softened, eg heat-softened, condition also apply to this aspect of the invention.
Thus, the orthognatic aspect of the invention provides a completely new philosophy in relieving temporo mandibular joint disorders caused by irregular dentition: In contrast to known orthognatic devices, the orthognatic device according to the invention is hinged in such a way that no interference between the upper and lower members may occur, thereby alleviating symptoms caused by abnormal interference from irregular dentition. Furthermore, tensions caused by tooth grinding and clenching are alleviated. At the same time, this orthognatic device is much easier to adapt to the individual needs of the person in question than conventional orthognatic devices, and it can even be used by the individual consumer without the assistance of any professional.
In the following, the successive mandibular advancement anti-snoring device aspect of the invention will be explained in further detail with reference to the accompanying drawings.
Description of figures
In the figures and drawings in which,
FIG. 1 Shows the Successive version of the mandibular advancement device in which a sliding system is indicated (the sliding system here is in the form of a "dovetail guide structure"). The device is seen from an oblique perspective from the bottom
FIG. 2 Shows the Successive version of the mandibular advancement device in an oblique perspective from the top part, in which a sliding system is indicated
FIG. 3 Shows the Successive version of the mandibular advancement device in a perpendicular perspective, in which a sliding system is indicated with its maximum elongation
FIG. 4 shows the sectional drawing of the device at line A in fig. 3 at its maximum elongation at the midline of the device
FIG. 5 shows the sectional drawing of the device at line B in fig. 3 at its maximum elongation at the junction of the device members
FIG. 6 shows the sectional drawing at line C in fig. 3 in which the engaging mechanism can be seen, further in detailed insert
FIG. 7 Shows the Successive version of the mandibular advancement device in which a sliding system is indicated (the sliding system here is in the form of a "dovetail guide structure"). The device is seen from an oblique perspective from the top in its detached situation
FIG. 8 Shows the Successive version of the mandibular advancement device in which a sliding system is indicated (the sliding system here is in the form of a "dovetail guide structure"). The device is seen from an oblique perspective from the top in its detached situation
FIG. 9 Shows a detailed enlargement of the negative structure of the
Successfully adjustable sliding mechanism depicted as a "dovetail guide"
FIG. 10 Shows a detailed enlargement of the positive structure of the Successive adjustable sliding mechanism depicted as a positive structure
FIG. 11 Shows the Successful version of the Adjustable Mandibular
Advancement Device top view in an oblique perspective in its Maximum elongated position with visible platforms for the engagement of one part of the Velcro system. Note that the platform can also be used as part of a gluing surface
FIG. 12 Shows the Successful version of the Adjustable Mandibular
Advancement Device bottom view in its Maximum elongated position.
Note that the platform connecting the two members can also be part of a gluing surface
FIG. 13 Shows the Successful version of the Adjustable Mandibular
Advancement Device top view in an oblique perspective in its detached position with visible platforms for the engagement of one part of the Velcro system or a glue
FIG. 14 Shows the Successive version of the Adjustable Mandibular
Advancement Device bottom view in an oblique perspective in its detached position with visible platforms for the engagement of one part of the Velcro system or a glue
FIG. 15 shows enlarged detail of one part of the connecting platforms on either upper mandibular or lower mandibular to engage with its corresponding counterpart by Velcro system or a glue
FIG. 16 shows enlarged illustration of the other part of the connecting platforms on either upper mandibular or lower mandibular to engage with its corresponding counterpart by Velcro system or a glue
FIG. 17 a Shows the heat applicable rod tool with its discoid handle and its pin in an oblique projection from above
FIG. 17 b Shows the two parts of the heat applicable rod tool separated
FIG. 17 c Shows the heat applicable rod tool with its handle and its pin from above, the A-A section describes in fig. 17 d
FIG. 17 d Shows the heat applicable in cross section from fig. 17 c in which the embedded rod is enclosed by the handle material
FIG. 18 Shows a diagrammatic representation of the limitations of the movements of the lower jaw in any direction in the sagital plane where PCP stands for the most protruded contact point of the teeth, IC stands for intercuspidal position (the maximum closing point), RCP stands for the most retracted contact position for the teeth, and MOP stands for the maximum opening point.
FIG. 19 Shows the Tubular Successive version of the Adjustable Mandibular Advancement Device shown in an activated and elongated detached view seen from a frontal oblique perspective shown in figs. 1 through 8.
FIG. 20 Shows the Tubular Successive version of the Adjustable Mandibular Advancement Device shown in an activated and elongated detached view seen from a bottom dorsal oblique perspective shown in figs. 1 through 8.
FIG. 21 Shows the Successful Version of the Adjustable Mandibular
Advancement Device shown in an activated and elongated detached view seen from a frontal oblique perspective shown in figs. 1 through 11.
FIG. 22 Shows the Successive version of the Adjustable Mandibular
Advancement Device shown in an activated and elongated detached view seen from a bottom dorsal oblique perspective shown in figs. 1 through 11.
Detailed description of the nomenclature used in the description of the FIGURES.
In Figs. 1-22, in which like numerals indicate like parts, the device 1 according to the invention consists of two horseshoe-like members 2 and 3 of a soft, resilient plastic material, preferably a thermoplastic material, such as an ethylene vinyl acetate copolymer, or any suitable material, hinged together by means of integrated resilient or mechanical hinges 4 and 4 '. Surfaces 5 and 6 represent the lower surface of the upper member and the upper surface of the lower member, respectively. 7 indicates the lingual flange of the lower member adapted to the lingual surfaces of the lower incisors, canines and premolars, this flange 7 being the part of the device which actually forces the lower jaw forward. 8 is the facial surface of the lower member, 9 is the facial surface of the upper member, and 10 is the lingual surface of the upper member. The conjoining effect of forces exerted by the facial surface 9 of the upper member and the lingual surface 7 of the lower member keep the lower jaw in a forward position relative to the upper jaw. As the facial surface 8 and the lingual surface 10 do not exert any forces, their dimensions are rather uncritical and some embodiments of the invention may also be provided without these surfaces. No. 11 indicates the tunnel-shaped space of the upper member 2 to engage with the upper dentition and 12 indicates the tunnel-shaped space of the lower member 3 adapted to engage the lower dentition. When the device is compressed to an active position, convexity 13 appears at the posterior end of the device and a concavity 14 at the anterior part of the hinging. The occusal knots 15 are designed to prevent complete occlusion and lack of airspace between the members 1 and 2. 17 is the Lateral facial portion of the mandibular member at the molar and premolar area, 18 is the medial palatine portion of the maxillary member at the molar and premolar area, 19 shows the Lingual wall of mandibular member closest to the tongue, 24 is the lateral facial portion of the maxillary member at the molar and premolar area, 25 the Lingual wall of mandibular member closest to the teeth, 26 the Mandibular member part of the invention with its positive structures of the successive mechanism, 27 the Hinge member part of the invention with its positive structure of the successive mechanism, 28 the Hinge member is part of the invention with its negative structures of the successive mechanism. 29 Upper or lower members with their positive structure of the successive part, 30 shows the Successive mechanism, 31 is the Positive structure of the successive mechanism, 32 the Negative structure of the successive mechanism. No. 33 is the Successive non specified 1st member of successive mechanism, 34 is the Successive non specified 2nd member of successive mechanism. In the figs. no. 35 indicates the Platform of the fingertip handle for the heating device, and 36 is the Edge of the fingertip handle for the heating device, where 37 is the Invagination part of the handpiece for holding the metal rod, 38 is the actual Metal rod. No. 39 is the intercuspidal position (IP) in which the dentition of the mandible makes the maximum interference with the dentition of the maxilla; 40 is the protruded contact position (PCP) in which the mandible has made the maximum protruded movement from the IP position, still keeping some contact with the dentition of the maxilla; 41 is the retracted contact position (RCP) in which the mandible has made the maximum retraction from the IP position, still keeping some contact with the dentition of the maxilla, and 42 is the maximal opening point (MOP) in which the mandible has made the maximum opening movement from the IP position, all of which is restricted to the muscles, teeth, ligaments and the discus involved in the temporomandibular joint system. 42 indicates the border describing the curve in which the mandible can slide open from the RCP, 43 is the border describing the curve in which the mandible can slide open from the PCP.
权利要求:
Claims (21)
[1] 1. A successive mandibular advancement anti-snoring and obstructive sleep apnea preventing device (1) comprising an upper member adapted to engage the maxillary dentition of a human and a lower member adapted to engage the mandibulary dentition of a human, characterized in that the upper and lower members are resilient or mechanical hinged at the most posterior part of the device and the members are successively adjustable to each other, whereby the hinging is adapted to allow physiological movements of the lower jaw in the sagital plane while retaining a forward position of the lower jaw relative to the upper jaw and thereby keeping the airway passage in the nasopharynx, the oropharynx and the hypopharynx substantially free of occlusion.
[2] 2. A successive mandibular advancement anti-snoring and obstructive sleep apnea preventing device (2) comprising an upper member adapted to engage the maxillary dentition of a human and a lower member adapted to engage the mandibulary dentition of a human, characterized in that the upper and lower members are resilient or mechanical hinged at the most posterior part of the device and one member (the mandibulary) is successively adjustable to the other (the maxillary), whereby the hinging is adapted to allow physiological movements of the lower jaw in the sagital plane while retaining a forward position of the lower jaw relative to the upper jaw and thereby keeping the airway passage in the nasopharynx, the oropharynx and the hypopharynx substantially free of occlusion.
[3] 3. A successive mandibular advancement anti-snoring and obstructive sleep apnea preventing device (3) comprising an upper member adapted to engage the maxillary dentition of a human and a lower member adapted to engage the mandibulary dentition of a human, characterized in that the upper and lower members are resilient or mechanical hinged at the most posterior part of the device and one member (the maxillary) is successively adjustable to the other (the mandibulary), whereby the hinging is adapted to allow physiological movements of the lower jaw in the sagital plane while retaining a forward position of the lower jaw relative to the upper jaw and thereby keeping the airway passage in the nasopharynx, the oropharynx and the hypopharynx substantially free of occlusion.
[4] 4. A device according to claim 1 in which the successive mechanism is embedded in the bodies of the maxillary and mandibulary members.
[5] 5. A device according to claim 2 in which the successive mechanism is embedded in the body of the mandibulary member.
[6] 6. A device according to claim 3 in which the successive mechanism is embedded in the body of the maxillary member.
[7] 7. A device according to any of the preceding claims wherein the successive mechanism is made of interlocking structures like hooks and loops, as in Velcro, where the mandibular part consists of hook and the opposing maxillary part consists of loops, or vice versa.
[8] 8. A device according to claim 7wherein the hooks and loops are microscopic, mesoscopic or macroscopic in sizes.
[9] 9. A device according to claim 7 wherein the hooks and loops are made of another non-toxic material different from the material used for the main maxillary and mandibulary members to engage the dentition of the human.
[10] 10. A device according to any of the claims 1-6 wherein the successive mechanism can be removed from the basic members of the device (upper maxillary, lower mandibulary and hinge), renewed, restored and reattached to the members again.
[11] 11. A device according to any of the claims 1-6 wherein the successive mechanism is constructed as a telescopic system, where one member is constructed as a cylinder and the other member is constructed as a rod or piston.
[12] 12. A device according to any of the claims 1-6 wherein the form of the successive telescopic mechanism differ from the circular for, i.e. square, rectangle, dovetail etc.
[13] 13. A device according to claim 11 wherein the cylinder and the piston rod are made of another non-toxic material different from the material used for the main maxillary and mandibulary members to engage the dentition of the human.
[14] 14. A device according to any of the claims 1-6 wherein the upper member is having an anterior wall adapted to be in contact with the facial surfaces of the incisors, canines and premolars of the upper jaw and lack lingual palatal walls to adapt to the palatal surfaces of the upper teeth, and a lower member having a posterior wall adapted to be in contact with the lingual surfaces of the incisors, canines and premolars of the lower jaw and lacking facial walls to engage with the facial surfaces of the lower teeth.
[15] 15. A device according to any of the preceding claims wherein a non-toxic plastics material is a thermoplastic material which can be shaped to adapt to an individual dentition by moderate heating.
[16] 16. A device according to any of the claims 1-6 wherein the upper and lower members are integrated with each other through resilient hinges made of the same material as the upper and lower members.
[17] 17. A device according to any of the claims 1-6 wherein the hinge is located in the most dorsal part of the device being embedded in or resilient due to the material itself.
[18] 18. A device according to claim 16 or 17 in which the most dorsal part of the hinge is convex at the most posterior part and concave at the most anterior part of the hinge when situated in the patients mouth.
[19] 19. A kit comprising a device according to any of the preceding claims together with a temperature indicator adapted to indicate the temperature change to an elevated temperature at which the material of the device can be shaped individually.
[20] 20. A kit according to claim 19 with a heatable metal rod combined with an insulating hand piece for the use of locking the sliding incremental process by means of penetration both members at the desired forward positioned maxillary member relative to the mandibulary member.
[21] 21. A method of manufacturing successive mandibular advancement device according to any of the claim 1 through 20.
类似技术:
公开号 | 公开日 | 专利标题
DK177992B1|2015-02-16|Successive Adjustable Mandibular Advancement Device For Preventing and Treatment of Snoring And Obstructive Sleep Apnea
US10543119B2|2020-01-28|Incremental and/or successive adjustable mandibular advancement device for preventing and treatment of snoring and obstructive sleep apnea
JP6899380B2|2021-07-07|Oral appliances
US4901737A|1990-02-20|Method and therapeutic apparatus for reducing snoring
KR101283760B1|2013-07-08|Method and device for mandibular advancement
EP0794749B1|2003-06-11|A jaw position-regulating oral device for preventing snoring
KR20130111848A|2013-10-11|An upper jaw and lower jaw a shifter
US9192455B1|2015-11-24|Oral appliances and methods of making oral appliances
EP2380533B1|2015-11-25|Intraoral splint
JP2014147623A|2014-08-21|Breathing corrector
同族专利:
公开号 | 公开日
DK177992B1|2015-02-16|
JP6387087B2|2018-09-05|
BR112015029484A2|2017-07-25|
AU2014277344A1|2015-11-26|
EP3003234A4|2017-01-11|
US9545331B2|2017-01-17|
US20140352700A1|2014-12-04|
CN105246437A|2016-01-13|
DK177809B1|2014-07-21|
WO2014194910A1|2014-12-11|
CA2912311A1|2014-12-11|
WO2014194910A9|2015-09-17|
JP2016519975A|2016-07-11|
SG11201509395WA|2015-12-30|
CA2912311C|2019-01-08|
RU2015148422A|2017-07-14|
EP3003234B1|2021-06-30|
EP3003234A1|2016-04-13|
AU2014277344B2|2018-11-15|
RU2657847C2|2018-06-15|
引用文献:
公开号 | 申请日 | 公开日 | 申请人 | 专利标题

USD273893S|1981-10-19|1984-05-15|Cooper Laboratories, Inc.|Hinged dental tray|
USD295218S|1985-11-21|1988-04-12|Kwok Lloyd A|Anterior articulator|
KR950012642B1|1987-10-13|1995-10-19|헤이스 앤드 미드 아이엔씨.|Dental orthosis for alleviation of snoring|
US4898535A|1988-04-11|1990-02-06|Bergersen Earl Olaf|Self-opening preformed activator and positioner|
CA2069426A1|1990-10-03|1992-04-04|Ernest Truffer|Snoring prevention device|
US5117816A|1991-01-03|1992-06-02|Shapiro Norman A|Anti-snore device|
GB2264868A|1992-03-06|1993-09-15|Robert Mateljan|Mandibular advancement device|
US5313960A|1992-11-04|1994-05-24|Marc S. Bernstein|Apparatus and method for reducing snoring and method of making same|
US6055986A|1992-11-16|2000-05-02|Meade; Thomas E.|Apparatus and method for the reduction of snoring|
US6729335B1|1993-04-13|2004-05-04|Silent Knights Ventures Inc.|Dental appliance for treatment of snoring and obstructive sleep apnea|
US6041784A|1993-04-13|2000-03-28|Silent Knights Ventures Inc.|Dental appliance for treatment of snoring and obstructive sleep apnea|
WO1994028832A1|1993-06-14|1994-12-22|Hilsen Kenneth L|Snoring and sleep apnea device|
USD358889S|1993-11-23|1995-05-30|Wong Norman K|Peripheal mucosa orthodontic tray|
DK131593A|1993-11-24|1995-06-13|Natashia Sonnie Ingemarsson|Mouth-worn shine for nighttime use against snoring and sleep apnea|
US5947724A|1995-06-23|1999-09-07|Frantz; Don E.|Elastic mandibular advancement appliance with slide-in bite planes|
AU744638B2|1998-07-06|2002-02-28|Somnomed Limited|A mandibular advancement device|
US6129084A|1998-10-22|2000-10-10|Bergersen; Earl O.|Intra-oral appliance for the prevention of snoring|
DE20102432U1|2001-02-12|2001-04-26|Hinz Verwaltungs Und Beteiligu|Device for applying a positioning force between the upper and lower jaw as a snoring aid|
USD492785S1|2003-06-25|2004-07-06|Ralph Garabito|Mouthpiece|
US20050236003A1|2004-04-16|2005-10-27|Meader Charles R|Apnea nipple and oral airway and mandibular advancement device|
US7520281B1|2004-05-06|2009-04-21|Group 3 Solutions, L.L.C.|Fixed therapeutic oral appliance|
EP1602347A1|2004-06-04|2005-12-07|Georges Magnin|Mandibular advancer orthesis.|
CN100522277C|2004-12-28|2009-08-05|学校法人久留米大学|Airway establishment appratus and stepless controller to be used therein|
USD529615S1|2005-04-13|2006-10-03|Atz Timothy K|Novelty mouthpiece|
ES2326033T3|2005-05-06|2009-09-29|Pierre Arni|MANDIBULAR PROPULSION DEVICE.|
US7730891B2|2005-10-07|2010-06-08|Lamberg Steven B|Intraoral mandibular advancement device for treatment of sleep disorders|
USD554260S1|2006-06-14|2007-10-30|Ric Investments, Llc|Oral appliance device|
US8613283B2|2006-06-19|2013-12-24|Insono Therapeutics, Inc.|Mandibular advancement appliance|
JP2010508131A|2006-11-07|2010-03-18|クリストファー・ケリー|Mandibular advancement device|
US20080115791A1|2006-11-21|2008-05-22|Andres Heine|Mandibular Advancement Mouthpiece, An Intraoccusal Removable Improved Device For Eliminating Or Reducing Snoring|
AT525035T|2007-04-23|2011-10-15|Distar L L C|DEVICE FOR ADJUSTING THE COASTER|
CA2687280A1|2007-05-17|2008-11-27|Michael Stubbs|Mandibular advancement device|
JP2011500178A|2007-10-19|2011-01-06|スキミット‐バイランドト,ジュルゲン|Mandibular protrusive system to prevent snoring and apnea|
WO2009062541A1|2007-11-12|2009-05-22|Oscimed Sa|Mandibular advancement orthosis|
US7810502B1|2007-11-19|2010-10-12|Nguyen Nghiep V|Anti-snoring and obstructive sleep apnea device|
USD604854S1|2008-05-06|2009-11-24|Mcdonald Simon Paul|Dental matrix retainer ring|
USD595857S1|2008-07-08|2009-07-07|Global Dental Impression Trays, Inc.|Preformed dental impression material|
DE202008010330U1|2008-08-01|2008-10-02|Köklü, Saduman Oguzhan, Dr.|Orthodontic apparatus|
CN102170844B|2008-10-03|2014-09-03|好眠有限公司|Mandibular advancement device with positive positioning hinge|
US8646455B2|2008-10-03|2014-02-11|Sleeping Well Llc|Mandibular advancement device with positive positioning hinge|
US8631800B2|2009-06-29|2014-01-21|Sleep Science Partners, Inc.|Self-titratable mandibular repositioning device|
USD632395S1|2009-08-03|2011-02-08|Global Dental Impression Trays, Inc.|Dental impression lower tray|
ES2365003B2|2009-10-22|2012-02-13|Laboratorio Ortoplus, S.L.|INTRA-ORAL DEVICE FOR ADJUSTABLE MANDIBULAR ADVANCE, APPLICABLE TO AVOID THE SOUND AND THE APNEA OF THE DREAM.|
USD642277S1|2009-12-23|2011-07-26|Christopher John Farrell|Oral appliance|
WO2011100355A1|2010-02-09|2011-08-18|Boyd James P|Multipurpose therapeutic mouthpiece assembly|
WO2011115962A1|2010-03-15|2011-09-22|Advanced Airway Design, Llc|Mandibular advancement splint|
US8534289B2|2010-03-22|2013-09-17|David Hernandez|Apparatus for reducing snoring|
US8833374B2|2010-12-13|2014-09-16|James S. Fallon|Intra-oral mandibular advancement appliance|
EP2529710A1|2011-06-02|2012-12-05|Carash Industries Ltd|A device for mandibular advancement|
US20130014765A1|2011-07-16|2013-01-17|Meade Thomas E|Tongue and mandibular advancement appliance|
WO2013049751A2|2011-09-30|2013-04-04|Robert Rogers|Oral orthotic systems, devices and methods for use in connection with sleep-disordered breathing|
FR2980684B1|2011-10-04|2014-08-22|Petelle Fleury Rech S Pfr|INTRABUCCAL ORTHESIS, METHOD OF MANUFACTURE, AND METHOD OF USING SUCH ORTHESIS.|
RU2491040C1|2011-12-26|2013-08-27|Вадим Александрович Луганский|Intraoral therapeutic apparatus by luganskiy|
US20130263865A1|2012-04-05|2013-10-10|Julian Omidi|Sleep apnea prevention assembly|
AU349029S|2012-08-31|2013-06-06|Orthodontic appliance|
USD710506S1|2013-04-12|2014-08-05|Elmer Tolentino|Mouth guard|
DK177809B1|2013-06-02|2014-07-21|Natashia Ingemarsson-Matzen|Incremental adjustable mandibular advancement device for|
US9687383B2|2013-06-02|2017-06-27|Petruska, Llc|Incremental and/or successive adjustable mandibular advancement device for preventing and treatment of snoring and obstructive sleep apnea|
USD739029S1|2013-11-05|2015-09-15|Ortho-Tain, Inc.|Dental appliance|
USD722171S1|2013-11-26|2015-02-03|Ortho-Tain, Inc.|Oral appliance|USD808022S1|2012-02-29|2018-01-16|Petruska, Llc|Oral device for preventing snoring and sleep apnea|
GB2502523B|2012-05-28|2018-01-31|Sleep Well Enjoy Life Ltd|Mandibular advancement device|
DK177809B1|2013-06-02|2014-07-21|Natashia Ingemarsson-Matzen|Incremental adjustable mandibular advancement device for|
US9687383B2|2013-06-02|2017-06-27|Petruska, Llc|Incremental and/or successive adjustable mandibular advancement device for preventing and treatment of snoring and obstructive sleep apnea|
WO2015123528A1|2014-02-13|2015-08-20|Silverfox Dental & Ortho, Llc|Oral motion preservation device|
US10537406B2|2014-02-21|2020-01-21|Align Technology, Inc.|Dental appliance with repositioning jaw elements|
US10772506B2|2014-07-07|2020-09-15|Align Technology, Inc.|Apparatus for dental confocal imaging|
US9675430B2|2014-08-15|2017-06-13|Align Technology, Inc.|Confocal imaging apparatus with curved focal surface|
US10449016B2|2014-09-19|2019-10-22|Align Technology, Inc.|Arch adjustment appliance|
US9610141B2|2014-09-19|2017-04-04|Align Technology, Inc.|Arch expanding appliance|
US9744001B2|2014-11-13|2017-08-29|Align Technology, Inc.|Dental appliance with cavity for an unerupted or erupting tooth|
US10504386B2|2015-01-27|2019-12-10|Align Technology, Inc.|Training method and system for oral-cavity-imaging-and-modeling equipment|
US10010313B2|2015-05-18|2018-07-03|Richard L. Arden|Mandibular subluxation device and method|
US10258319B2|2015-05-18|2019-04-16|Richard L. Arden|Airway assist device and method|
USD778449S1|2015-06-17|2017-02-07|Natashia Ingemarsson-Matzen|Dental plate|
US10342526B2|2015-07-01|2019-07-09|Richard L. Arden|Airway assist device and method|
US10248883B2|2015-08-20|2019-04-02|Align Technology, Inc.|Photograph-based assessment of dental treatments and procedures|
US11103330B2|2015-12-09|2021-08-31|Align Technology, Inc.|Dental attachment placement structure|
US11167141B2|2016-03-15|2021-11-09|Leonhardt Ventures Llc|Bioelectric blood pressure management|
US11185691B2|2016-03-15|2021-11-30|Leonhardt Ventures Llc|Tumor therapy|
WO2017218951A1|2016-06-17|2017-12-21|Align Technology, Inc.|Orthodontic appliance performance monitor|
EP3471599A4|2016-06-17|2020-01-08|Align Technology, Inc.|Intraoral appliances with sensing|
EP3487439A4|2016-07-22|2020-04-08|Prosomnus Sleep Technologies, Inc.|Computer aided design matrix for the manufacture of dental devices|
EP3578131B1|2016-07-27|2020-12-09|Align Technology, Inc.|Intraoral scanner with dental diagnostics capabilities|
US10507087B2|2016-07-27|2019-12-17|Align Technology, Inc.|Methods and apparatuses for forming a three-dimensional volumetric model of a subject's teeth|
CN113648088A|2016-11-04|2021-11-16|阿莱恩技术有限公司|Method and apparatus for dental images|
US11026831B2|2016-12-02|2021-06-08|Align Technology, Inc.|Dental appliance features for speech enhancement|
CN110062609B|2016-12-02|2021-07-06|阿莱恩技术有限公司|Method and apparatus for customizing a rapid palate expander using a digital model|
US10548700B2|2016-12-16|2020-02-04|Align Technology, Inc.|Dental appliance etch template|
US10456043B2|2017-01-12|2019-10-29|Align Technology, Inc.|Compact confocal dental scanning apparatus|
US10779718B2|2017-02-13|2020-09-22|Align Technology, Inc.|Cheek retractor and mobile device holder|
US10613515B2|2017-03-31|2020-04-07|Align Technology, Inc.|Orthodontic appliances including at least partially un-erupted teeth and method of forming them|
USD832447S1|2017-04-26|2018-10-30|Richard Wiffen|Oral device|
US11045283B2|2017-06-09|2021-06-29|Align Technology, Inc.|Palatal expander with skeletal anchorage devices|
US10639134B2|2017-06-26|2020-05-05|Align Technology, Inc.|Biosensor performance indicator for intraoral appliances|
US10885521B2|2017-07-17|2021-01-05|Align Technology, Inc.|Method and apparatuses for interactive ordering of dental aligners|
EP3658067A1|2017-07-27|2020-06-03|Align Technology, Inc.|System and methods for processing an orthodontic aligner by means of an optical coherence tomography|
US11116605B2|2017-08-15|2021-09-14|Align Technology, Inc.|Buccal corridor assessment and computation|
WO2019036677A1|2017-08-17|2019-02-21|Align Technology, Inc.|Dental appliance compliance monitoring|
USD881399S1|2017-08-30|2020-04-14|Natashia Ingemarsson-Matzen|Dental plate|
US10813720B2|2017-10-05|2020-10-27|Align Technology, Inc.|Interproximal reduction templates|
US11096763B2|2017-11-01|2021-08-24|Align Technology, Inc.|Automatic treatment planning|
CN111417357A|2017-11-30|2020-07-14|阿莱恩技术有限公司|Sensor for monitoring oral appliance|
US10980613B2|2017-12-29|2021-04-20|Align Technology, Inc.|Augmented reality enhancements for dental practitioners|
US11013581B2|2018-01-26|2021-05-25|Align Technology, Inc.|Diagnostic intraoral methods and apparatuses|
US11123219B2|2018-04-05|2021-09-21|Oscar TAMEZ|Mouth appliance and a method to improve breathing during sleep and exercise|
CN109498941A|2018-12-19|2019-03-22|南京医科大学附属逸夫医院|Anaesthetize mouth pad|
USD888249S1|2019-01-15|2020-06-23|Ryan Bruss|Mouthguard|
US11266837B2|2019-03-06|2022-03-08|Medtronic Xomed, Inc.|Position sensitive lingual muscle simulation system for obstructive sleep apnea|
USD932626S1|2020-05-13|2021-10-05|ProSomnus Sleep Technologies, Inc.|Mandibular advancement device with comfort bumps|
US11246745B1|2020-12-31|2022-02-15|King Abdulaziz University|Sleep apnea treatment system|
RU2751970C1|2021-01-29|2021-07-21|Павел Евгеньевич Михальченко|Anti-snoring device|
法律状态:
2022-01-14| PBP| Patent lapsed|Effective date: 20210602 |
优先权:
申请号 | 申请日 | 专利标题
DK201300338A|DK177809B1|2013-06-02|2013-06-02|Incremental adjustable mandibular advancement device for|
DK201300338|2013-06-02|
DK201400149A|DK177992B1|2013-06-02|2014-03-17|Successive Adjustable Mandibular Advancement Device For Preventing and Treatment of Snoring And Obstructive Sleep Apnea|
DK201400149|2014-03-17|DK201400149A| DK177992B1|2013-06-02|2014-03-17|Successive Adjustable Mandibular Advancement Device For Preventing and Treatment of Snoring And Obstructive Sleep Apnea|
[返回顶部]