• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    cannula with floating clamp member. it is a cannula (100) having a longitudinal base member (102) having a first clipping end and a longitudinal arm member (104) pivotally attached (110) to the longitudinal base member and having a second stapling end, the cannula being in a closed position when the first and second stapling ends are brought together. a first clip member (120) is located at the first clip end and has a first passage (122). a second clip member (108) is pivotally attached to the arm member at the second clipping end and has a second passage (170). the first and second passages form a combined passage when the clamp is in the closed position. the cannula may have a first locking member (132) positioned on the arm member and a second locking member (130) positioned on the base member. the first and second locking members interact with each other to lock the cannula in the closed position.
    公开号:BR112015000498B1
    申请号:R112015000498-9
    申请日:2013-07-08
    公开日:2021-09-14
    发明作者:Christopher P. Steinman；Jason A. Belton；Kirk C. Palmerton；Karl H. Beitzel；Rick W. Walker；Matthew Copithorne；Brian Otts；James V. Guarrera
    申请人:Lifeline Scientific, Inc；
    IPC主号:
    专利说明:

    BACKGROUND
    [0001] Related art fields include cannulae and stapling methods which include cannulae and stapling methods for perfusing one or more organs or tissue to monitor, treat, maintain and/or restore the viability of the organ(s) or tissue and/or to transport and/or store the organ(s) or tissue.
    [0002] Several devices have been developed that couple the anatomy of an organ that is subjected to perfusion to a perfusion machine or other equipment such as that described in Patent Document No. 7,824,848, the disclosure of which is incorporated herein by way of reference. Such devices are typically termed as perfusion clamps or simply cannulas. Although the term cannula in general use has other meanings, the term cannula is used generically throughout this specification to refer to a clamp or other device that provides a connection through which fluid flow can be stabilized.
    [0003] A type of cannula as described in U.S. Patent Document 5,728,115 by Westcott et al. is shown in Figures 1 to 3. A clamping device (cannula) 10 is used to attach a perfusion device to the renal aorta 34. Clamp 10 includes two longitudinal members 12 and 14 that pivot around a pin 16. The end The proximal end of member 12 includes an integral handle 18, while the proximal end of member 14 includes an integral handle 20. The distal end of member 12 includes an integral elongated hollow annular clip head 24 while the distal end of member 14 includes an elongated, hollow, annular, integral clip head 26. Clip head 26 includes a spout 28 secured thereto. Movement of handles 18 and 20 towards each other forces members 12 and 14 to pivot around pin 16, thus forcing clamp heads 24 and 26 of members 12 and 14 away from each other. A spring 22 is positioned between the handles 18 and 20 so as to tilt the handles away from each other. This, in turn, tends to force clamp heads 24 and 26 together. Therefore, clamp heads 24 and 26 of the distal ends of members 12 and 14 are engaged in clamping relationship unless an external compressive force is applied to handles 18 and 20. A lumen 32 extends through nozzle 28 .
    [0004] In use, the clamp 10 is fixed to a blood vessel of a donor organ such as the renal aorta 34 of a kidney 36 by opening the clamp 10, passing the distal end 38 of the renal aorta 34 through the annular clamp head 24, the distal end 38 of the renal aorta 34 being held over the annular clamp head 24, and releasing pressure on the clamp handles 10 to allow the clamp head 26 to engage the distal end 38 of the aorta renal 34 against annular clamp head 24. A catheter 40 can then be attached to nozzle 28 to provide fluid perfusion through lumen 32 and to renal aorta 34. SUMMARY
    [0005] In the cannula described above, the orientation of the clip heads 24 and 26 in relation to each other is fixed due to the fact that the clip heads 24 and 26 are integral to the members 12 and 14, respectively. Consequently, the force applied to the fabric during the stapling process can be unevenly distributed across the fabric surface, potentially thereby resulting in tissue damage or an inadequate grip that is susceptible to failure. Additionally, although the cannula shown in Figures 1 to 3 is tilted in the closed or clamping position by spring 22, the cannula does not include a locking mechanism to prevent the cannula from opening at an undesired time. In addition, the cannula shown in Figures 1 to 3 provides poor visibility of the vasculature due to the fact that it has a limited range of motion and due to the fact that the clamp heads 24 and 26 are made of an opaque material (typically metal) . The limited range of motion also limits access to staple heads 24 and 26, increasing difficulty of use. Furthermore, the spout 28 may be susceptible to leakage due to a relatively soft construction and the spring 22 does not allow adjustment of the force applied to the stapled fabric.
    [0006] In exemplary embodiments, a clamp such as a cannula includes a longitudinal base member and a longitudinal arm member pivotally attached to the longitudinal base member. The clamp also includes a first clamp member at a first end of the base member and a second clamp member pivotally secured to the arm member at a first end of the arm member, the first clamp member opposing the second member. of staple. The second clamp member may be movable in more rotational axes and/or more rotational directions relative to the arm member than the arm member is movable relative to the base member. Additionally, the second clip member may have one or more than one degree of freedom of movement with respect to the arm member, for example, two degrees of rotation of freedom with respect to the arm member.
    [0007] Pivotally securing the second staple member to the arm member allows the force applied to the fabric during the stapling process to be evenly distributed, thus reducing tissue damage. Additionally, fabric grip may be less likely to fail. In addition, pivotally securing the second clip member to the arm member may allow a first clipping surface to have a variable position relative to a second clipping surface when the arm member and base member are held in place. place in relation to each other.
    [0008] In exemplary embodiments, a clamp such as a cannula includes a longitudinal base member having a first clamping end and a longitudinal arm member pivotally attached to the longitudinal base member and having a second clamping end. The staple is in a closed position when the first and second staple ends are placed together. The clamp also includes a first locking member positioned on the arm member and a second locking member positioned on the base member. The first and second locking members interact with each other to slidably lock the clamp in the closed position.
    [0009] In exemplary embodiments, a clamp such as a cannula includes a longitudinal base member having a first clamping end and a longitudinal arm member pivotally attached to the longitudinal base member and having a second clamping end, wherein the staple is in a closed position when the first and second staple ends are placed together. The clamp also includes a first clamp member at a first end of the base member and a second clamp member movably (e.g., pivotally) secured to the arm member at a first end of the arm member, the first of which end of the arm member opposes the first end of the base member. Additionally, the clamp includes a first locking member positioned on the arm member and a second locking member positioned on the base member. The first and second locking members interact with each other to slidably lock the clamp in the closed position.
    [0010] In exemplary embodiments, a method for clamping or cannulating a blood vessel includes clamping the blood vessel between a first clamp surface that applies a first force to the blood vessel and a second clamp surface that applies a second force to the blood vessel. . A magnitude of the first force is substantially consistent over an entire surface of the blood vessel that is in contact with the first and second clamp surfaces. Clamping or cannulating the blood vessel can facilitate a connection between the blood vessel and an infusion device. BRIEF DESCRIPTION OF THE DRAWINGS
    [0011] Exemplary deployments can be described with reference to the Figures below, in which:
    [0012] Figures 1 to 3 illustrate a prior art cannula;
    [0013] Figure 4 illustrates an exemplary stapling apparatus in a closed position;
    [0014] Figure 5 illustrates an exemplary stapling apparatus of Figure 4 in an open position;
    [0015] Figure 6 illustrates an exemplary base member of the clipping apparatus of Figures 4 and 5;
    [0016] Figure 7A illustrates an exemplary floating clip member of the clipping apparatus of Figures 4 and 5;
    [0017] Figure 7B illustrates another view of the floating clamp member of Figure 7A;
    [0018] Figure 8 illustrates an exemplary floating clip member seat of the clipping apparatus of Figures 4 and 5; and
    [0019] Figure 9 illustrates illustrative stapling surfaces of the stapling apparatus of Figures 4 and 5. DETAILED DESCRIPTION OF MODALITIES
    [0020] Figure 4 shows a perfusion stapling apparatus or cannula 100 according to exemplary embodiments. Cannula 100 is capable of connecting one or more blood vessels of an organ or tissue to a perfusion machine or system (not shown) such as that described in Patent Document No. 7,824,848, the disclosure of which is incorporated herein into reference title, for example, by connection to the piping of the perfusion machine or system. All medical fluid contact surfaces are preferably formed of materials compatible with or coated with the medical fluid used, preferably non-thrombogenic materials. For convenience, the term "organ" will be used herein to mean organ and/or tissue, except as otherwise specified.
    The medical fluid for infusion may be any suitable medical fluid. For example, it can be a simple crystalloid solution, or it can be added with an appropriate oxygen carrier. The oxygen carrier can be, for example, washed, stabilized red cells, cross-linked hemoglobin, pegolated hemoglobin or fluorocarbon based emulsions. The medical fluid may also contain antioxidants known to reduce peroxidation or free radical damage in the physiological environment and specific agents known to aid in tissue protection. Also, the medical fluid can be or include blood or blood products.
    The cannula 100 is shown in Figure 4 in a closed or stapled condition and in Figure 5 in an open condition. Cannula 100 may comprise a base 102, an arm 104, an optional locking mechanism 106, and a floating clamp member 108. Although the floating clamp member 108 is illustrated as being secured to the arm 104, it is contemplated that the clamp member Float 108 may be secured to base 102 instead of arm 104. It is also contemplated that both base 102 and arm 104 may be secured to respective float clamp members 108. Base 102 and arm 104 may be pivotally connected by means of a pivot mechanism 110. As illustrated, the pivot mechanism 110 may be a pin around which one or both the base 102 and the arm 104 may pivot. Pivot mechanism 110 can be positioned anywhere between a distal end 112 and a clamping end 114 of cannula 100. As seen in Figure 4, when cannula 100 is in the closed condition, base 102 and arm 104 are placed together at the distal end 112 and at the clamping end 114. As seen in Figure 5, when the cannula 100 is in the open condition, the base 102 and arm 104 are moved apart from each other at the distal end 112 and at the end. of clamping 114. When being rotated from the closed condition to the open condition, the arm 104 and/or base 102 can be rotated as much or more than 180 degrees.
    [0023] The base 102 and the arm 104 may be pivotable around a geometric axis 116 of the pivot mechanism 110 extending in a first direction and may be adjacent to each other on the pivot mechanism 110 in the first direction. The first direction may be perpendicular to a longitudinal geometric axis of cannula 100. Base 102 and arm 104 may also be adjacent to each other in the first direction at distal end 112, but may be adjacent to each other in a second direction at staple end 114. The second direction may be different from the first direction. The second direction is preferably, but not necessarily, substantially perpendicular to the first direction. For example, Figure 4 illustrates base 102 and arm 104 as being adjacent to each other in pivot mechanism 110 in a side-by-side (i.e., adjacent in the first direction) configuration. Figure 4 also illustrates base 102 and arm 104 as being overlapped at clamping end 114 in a stacked configuration (i.e., overlapped in the second direction). Base 102 and arm 104 are preferably pivotable relative to one another only around axis 116.
    [0024] As illustrated in Figures 4 and 5, preferably there is no biasing member (such as the spring 22 shown in Figure 1) that tilts the cannula 100 to both a closed position and an open position. Such a lack of a tilting member may be advantageous in that the cannula 100 can be opened or closed, or adjusted to any position in between, and remain in that position without further action by a user. If such a tilting member were included, more structure, such as a stopper or locking mechanism, could be added to take advantage of the cannula 100 remaining in a user-configured position (other than the position indicated by the tilting member). A lack of tilting member can also allow the cannula 100 to open more than if a tilting member is provided. For example, spring 22 shown in Figure 1 requires cannula 10 to be compressed to open, and there is limited displacement between handles 18 and 20, which results in limited opening space between clamp heads 24 and 26. , the cannula 100 shown in Figures 4 and 5 is not so limited. Cannula 100 has a pinch-to-close action opposite to the pinch-to-open action of cannula 10. By including a pinch-to-close action and tilting member, cannula 100 can be opened in a much greater range than is possible with the cannula 10 of Figure 1. Furthermore, such a pinch-to-close configuration without a tilt member can allow for intermediate positions or stopping points between a fully open position and a fully closed position. Any desired stopping points can be provided with the frame that tends to hold the cannula 100 in an intermediate position. Such a structure could be achieved, for example, with the use of detents (not shown). However, someone of ordinary skill would find that the cannula 100 could include a tilting member that tilts the cannula 100 both open and closed if the needs of a user so dictate.
    The base member 102 may include a first gripping portion 118 and a clipping portion 120. The first gripping portion 118 may extend from the distal end 112 of the cannula 100 to near the clipping members, for example , the optional locking mechanism 106, and can be economically configured to receive at least a first portion of a user's right and/or left hand. Clamping portion 120 may be integrally formed with base member 102 or may be a separately formed component. Additionally, the clamping portion 120 may include an opening 122 through which an aortic patch or other type of vasculature of an organ may be fed. Clamping portion 120 may also include a first clamping surface 124 that is configured to cooperate with floating clamp member 108 to clamp the aortic patch or other type of organ vasculature.
    The arm member 104 may include a second gripping portion 126 and a floating clip member seat 128. The second gripping portion 126 may extend from the distal end 112 of the cannula 100 to near the clipping members. , for example, the optional locking mechanism 106, and can be economically configured to receive at least a second portion of the user's right and/or left hand. Floating clamp member seat 128 may be configured to receive and support floating clamp member 108.
    The cannula 100 may preferably be configured to be operated (i.e. moved from open to closed condition or moved from closed to open condition) by a user's hand. Additionally, the cannula 100 can be economically configured to be used by either a user's left or right hand. For example, in a left-hand configuration (as shown in all figures), base 102 can be positioned to the right of arm 104 on pivot mechanism 110 when cannula 100 is oriented so that clamping end 114 is farthest away. of user. In contrast, in a right-hand configuration (a mirror image of what is shown in all Figures), base 102 can be positioned to the left of arm 104 on pivot mechanism 110 when cannula 100 is oriented so that the end of clipping 114 is further away from the user.
    [0028] The optional locking member 106 can lock the cannula 100 in the closed condition. Preferred embodiments may include a primary locking member 130, a toothed member 132, and an optional secondary locking member 134. The primary locking member 130 is pivotally connected to the base 102 and may include an interacting portion 136, an unlocking portion. 138 and an inclination portion 140. Interacting portion 136 may extend from base 102 toward toothed member 132 secured to arm 104 and may pivot between a locked position and an unlocked position. Interacting portion 136 may include a hook-like portion 142 that may be positioned between the tooth of tine member 132. When the hook-like portion 142 is hooked onto a tooth of tine member 132, locking member 106 prevents allow arm 104 to pivot open relative to base 102. It is contemplated that toothed member 132 may be flexible or pivotally secured to arm 104. In either case, toothed member 132 may optionally be tilted. It is also contemplated that primary latch member 130 may be pivotally connected to arm 104 and toothed member 132 may be flexible or pivotally secured to base 102.
    [0029] The unlocking portion 138 may be connected to the interaction portion 136 on a pivot 144 such that, when the unlocking portion 138 is pivoted around the pivot 144, the interaction portion is also pivoted around the pivot . The unlocking portion 138 is preferably positioned so that the base 102 is between the unlocking portion 138 and the interacting portion 136. Consequently, pressing the unlocking portion 138 towards the base member 102 may cause the interaction portion 136 moves to the unlocked position. Conversely, allowing the unlocking portion 138 to pivot away from the base member 102 may cause the interacting portion 136 to move into the locked position.
    [0030] The tilting member 140 is optional, and may be a spring-like element extending from the interacting portion 136 towards the base 102. The tilting member may apply a tilting force that deviates from the interacting portion 136 toward the locked position.
    [0031] The optional secondary locking member 134 may include a first slide member 146 (as shown in Figure 4) and a second slide member 148 (as shown in Figure 6). The first sliding member 146 may be positioned on the same side of the base 102 as the interacting portion 136. Positioning the first sliding member 146 in this manner may allow the optional secondary locking member 134 to be actuated by the user's thumb. The first sliding member 146 is slidable towards and away from the interacting portion 136. Second sliding member 148 may be positioned on the same side of base 102 as unlocking portion 138 and is slidable toward and away from unlocking portion 138. The first and second sliding members 146 and 148 are connected to each other so that when the first sliding member 146 is moved in a particular direction, the second sliding member 148 is moved in the same direction. Additionally, the second sliding member 148 is positioned such that when the second sliding member 148 is moved towards the unlocking portion 138, the second sliding member 148 is moved between the base 102 and the unlocking portion 138. The effect of preventing the unlocking portion 138 from being pressed towards the base 102. Consequently, although the second sliding member 148 is between the unlocking portion 138 and the base 102, the interacting portion 136 cannot be moved to the unlocked position, and the cannula 100 cannot be moved from the closed to the open condition. This is advantageous due to the fact that the cannula 100 is less likely to unintentionally open, which could result in loss of or damage to an organ that has been cannulated.
    [0032] The first sliding member 146 can be omitted from the secondary locking member 134. In an embodiment without the first sliding member 146, the user can operate the optional secondary locking member 134 by sliding the second sliding member 148, which can be completed with one of the user's fingers.
    [0033] As illustrated in Figures 7A and 7B the floating clamp member 108 may include a coupling portion 150, a support portion 152 and a cup portion 154. The coupling portion 150 may form a tubular structure and may provide a connection (such as a hose barb or luer lock) to a tube or other fluid conduit that connects cannula 100 to the infusion machine or system (not shown). Use of a hose barb or luer lock is advantageous due to the fact that such structures are less likely to leak than the nozzle 28 shown in Figures 1 to 3.
    [0034] In embodiments, the cannula 100 may include features that allow the second clamping surface 178 to change an angle relative to the first clamping surface 124 other than by moving the base 102 and the arm 104. The relative angle shift it can be around one or more geometric axes. Such a change in angle can allow cannula 100 to clip or cannulae varying thicknesses of tissue in a single blood vessel or the like that would otherwise prove problematic with a cannula that does not allow similar relative angle changes between clipping surfaces. For example, with a cannula that does not allow for a relative change of angle between stapling surfaces, it may be necessary to over-compress, and possibly damage, a blood vessel that is cannulated or stapled in order to produce a proper seal. Alternatively, a leaky seal may be required in order to prevent damage to the blood vessel.
    [0035] In the depicted embodiment, support portion 152 may include a plurality of features for connecting floating clip member 108 to arm 104. For example, support portion may include a main body 156, upper primary support members 158 , lower primary support members 160 and secondary support members 162. Upper primary support members 158 may be projections of main body 156 and may each have a substantially horizontal bottom surface 164. Lower primary support members 160 they may be positioned closer to the cup portion 154 than the upper primary support members 156 and may also be projections of the main body 156. The lower primary support members 160 may each have substantially horizontal top surfaces 166. secondary support members 162 may be positioned closer to cup portion 154 than lower primary support members. rods 160 and may also be projections of main body 156. Alternatively, lower primary support members 160 may be positioned closer to cup portion 154 than secondary support members 162. Any of these offset configurations may be advantageous by the fact that, by interacting with the corresponding compatible structure on the floating clamp member seat 128, two pivotal degrees of freedom can be achieved by preventing a pivotal third degree of freedom. The secondary support members 162 may each have horizontal top surfaces 168. The upper primary support members 158 may preferably be on opposite sides of the main body 156 from each other, the lower primary support members 160 may preferably be at cross-sections. opposite sides of the main body 156 from each other and/or the secondary support members 162 may preferably be on opposite sides of the main body 156 from each other. The upper primary support members 158 and the lower primary support members 160 may be of similar or different shapes and sizes.
    [0036] As can be seen in Figure 8, the floating clamp member seat 128 may include an opening 170 through which the floating clamp member 108 can be inserted and a support portion 172 surrounding the opening 170 that can support the floating clip member 108. The support portion 172 may include a plurality of first recesses 174 and a plurality of second recesses 176. The first recesses 174 may each be configured to receive a corresponding upper primary support member 158. Additionally, each first recess 174 may be shaped complementary to the corresponding upper primary support member 158. For example, each of the first recesses 174 can be closed at the bottom and can be opened at the top. The first recesses 174 may be dimensioned to have a larger volume than the respective corresponding upper primary support members 158 so that the upper primary support members 158 may be free to move within the respective corresponding first recesses 174.
    The second recesses 176 may each be configured to receive a corresponding lower primary support member 160. Additionally, each second recess 176 may be shaped complementary to the corresponding lower primary support member 160. For example, each of the second recesses 176 may be open at the bottom and closed at the top. The second recesses 176 may be sized to have a greater volume than the respective corresponding lower primary support members 160 so that the lower primary support members 160 may be free to move within the respective corresponding second recesses 176.
    [0038] The configuration of the support portion 172 within the floating clamp member seat 128 may allow the floating clamp member 108 to rotate around more than one geometric axis. For example, the floating clamp member 108 may rotate about an axis 180 that extends through the centers of the upper primary support members 158. The axis 180 may extend along a plane that is parallel to a plane. axial longitudinal axis of the cannula 100. The floating clamp member 108 may also rotate about a axis 182 that extends through the centers of the lower primary support members 160. The axis 182 may also extend along a plane that it is parallel to the axial longitudinal plane of the stapling apparatus. Other structures that allow at least two degrees of rotation between floating clamp member 108 and arm 104 are contemplated by the inventive principles discussed herein.
    [0039] By allowing the floating clamp member 108 to rotate around two or more different geometric axes, the orientation of a second clamping surface 178 can be variable relative to the orientation of the first clamping surface 124. Cannula 100 can be more sensitive to variations in the thickness of the tissue that is stapled, thus reducing the amount of tissue damage that can occur during the stapling process and reducing the likelihood that the grip will fail. Such rotation about two or more different geometric axes also allows the first stapling surface 124 and the second stapling surface 178 to approach and/or engage with each other, or engage the stapled fabric, in a parallel manner. In this way, the integrity of each stapling surface will engage as closely as practicable, which can result in more uniform application of stapling force and less likelihood of damage (or uneven damage) to the stapled fabric. Uniformly distributed clamping force can also be obtained, which can result in a superior seal versus clamping surfaces that cannot achieve such relative movement. Preferably, the floating clamp member 108 has a range of motion around each geometric axis around 15 degrees (7.5 degrees of positive and negative rotation for each axis) and more preferably around 12 degrees (6 degrees of positive and negative rotation for each geometry axis) to avoid superfluous movement.
    [0040] The cup portion 154 of the floating staple member 108 may include the second stapling surface 178, which interacts with the first stapling surface 124 of the base 102 to staple the fabric. As can be seen in Figure 9, one stapling surface (eg, second stapling surface 178) may have a larger diameter than the other stapling surface (eg, first stapling surface 124). Although Figure 9 illustrates second clamping surface 178 having a larger diameter than first clamping surface 124, it is contemplated that first clamping surface 124 may have the larger diameter. Additionally, one stapling surface may have a staggered shape along a perimeter, while the other stapling surface may have a complementary shape to the staggered shape of a stapling surface to form a tighter seal around the stapled fabric. Alternatively, first stapling surface 124 and second stapling surface 178 can have similar cross-sectional shapes. It should be understood that, while in the closed position, the clamping surfaces may be in contact with each other or separated by a suitable distance (eg 0.5 mm to 4.00 mm, more preferably 1.0 mm to 3.0 mm) to accommodate fabric.
    The cannula 100 can be made of any suitable material or materials, such as metal or clear or opaque plastics, but plastics provide several advantages. Plastics are generally less expensive, and therefore can be made available. A disposable version of the cannula 100 will not have the additional costs associated with reuse, such as resterilization.
    [0042] Portions of the cannula 100 can be produced from optically transparent material. This can be beneficial in that it can help a clinician to position the vasculature and detect air bubbles or the interior or inner lining of the vasculature.
    Both the first stapling surface 124 and/or the second stapling surface 178 may include serrations and/or protrusions to help secure the stapled fabric. If the serrations or protrusions are made of plastic, plastics can be chosen with specific material properties to limit or prevent damage to the stapled fabric. Additionally, serrations or protrusions can be specifically adapted to the fabric to be stapled. The first stapling surface 124 and/or the second stapling surface 178 may include an elastomeric material to work together with the serrations and/or protrusions and/or be replaced by the same.
    [0044] Although various features have been described in conjunction with the examples highlighted above, various alternatives, modifications, variations, and/or enhancements to these features and/or examples may be possible. Consequently, the examples as presented above are intended to be illustrative. A number of changes can be made without departing from the broad spirit and scope of the underlying inventive principles.
    权利要求:
    Claims (15)
    [0001]
    1. Cannula (100) comprising: a longitudinal base member (102); a longitudinal arm member (104) pivotally secured to the longitudinal base member (102); a first clamp member (120) having a first passage and located at a first end of the base member; a second clip member (108) pivotally attached to the arm member at a first end of the arm member, the second clip member (108) having a second passageway and is opposite the first clip member (120) at whereas the first and second passages form a combined passage when the cannula (100) is in a closed position, the cannula (100) characterized in that the second clip member (108) is pivotally secured to the arm member at the first end. of the arm member such that the second clip member (108) has two rotational degrees of freedom relative to the arm member to more evenly distribute the force applied to tissue during a cannula fixation process (100).
    [0002]
    2. Cannula (100) according to claim 1, characterized in that the second clip member (108) is movable in more rotational directions with respect to the arm member than the arm member is movable with respect to the base member.
    [0003]
    3. Cannula (100) according to claim 1, characterized in that the arm member has a rotational degree of freedom in relation to the base member.
    [0004]
    4. Cannula (100) according to claim 1, characterized in that the first clip member (120) has a first clip surface (124) and the second clip member (108) has a second clip surface. clamp (178), and an orientation of the second clamp surface (178) relative to the first clamp surface (124) is variable while the longitudinal base member (102) and the longitudinal arm member (104) are so retained. stationary in relation to each other.
    [0005]
    5. Cannula (100) according to claim 4, characterized in that the first clamp member (120) is fixedly attached to the base member.
    [0006]
    6. Cannula (100) according to claim 1, characterized in that the first end of the arm member is configured to move towards the first end of the base member when the cannula (100) is moved to the closed position and the first end of the arm member is configured to move away from the first end of the base member when the cannula (100) is moved to an open position.
    [0007]
    7. Cannula (100) according to claim 6, characterized in that a second end of the arm member is configured to move towards a second end of the base member when the cannula (100) is moved to the closed position and the second end of the arm member is configured to move away from the second end of the base member when the cannula (100) is moved to the open position.
    [0008]
    8. Cannula (100) according to claim 1, characterized in that the first and second clip members are formed from a transparent material.
    [0009]
    9. Cannula (100) according to claim 1, characterized in that the arm member and the base member are adjacent to each other in a first direction at a point where the arm member and the base member are pivotally fixed and a first clip surface (124) of the first clip member (120) and a second clip surface (178) of the second clip member (108) are adjacent, one in relation. to the other, in the closed position in a second direction that is different from the first direction.
    [0010]
    10. Cannula (100), according to claim 9, characterized in that the second direction is perpendicular to the first direction.
    [0011]
    11. Cannula (100) according to claim 1, characterized in that the cannula (100) is openable to form an angle between the base member and the arm member that is at least 160 degrees when the cannula (100) is in an open position.
    [0012]
    12. Cannula (100) according to claim 11, characterized in that the angle is at least 180 degrees.
    [0013]
    13. Cannula (100) according to claim 1, characterized in that it further comprises: a first locking mechanism (130) configured to selectively lock the cannula (100) in a closed position; and a second locking mechanism (134) configured to selectively maintain the first locking mechanism (130) in a locked position.
    [0014]
    14. Cannula (100) according to claim 13, characterized in that the first locking mechanism (130) includes a primary locking member (136) pivotally fixed to the base member and the second locking member includes a first sliding member (146) slidably attached to the primary locking member (136).
    [0015]
    15. Cannula (100) according to claim 14, characterized in that the first locking mechanism (130) includes an unlocking member (138) pivotally movable between a locked position in which the primary locking member (136 ) interacts with the first sliding member (146) and an unlocked position where the primary locking member (136) does not interact with the first sliding member.
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    同族专利:
    公开号 | 公开日
    CN104619167A|2015-05-13|
    US9629359B2|2017-04-25|
    CA2917870C|2019-10-29|
    CA2917870A1|2014-01-16|
    BR112015000498A2|2020-10-20|
    EP2871942A2|2015-05-20|
    EP2871942B1|2016-08-31|
    CN104619167B|2017-03-08|
    ES2605832T3|2017-03-16|
    US8814889B2|2014-08-26|
    US20140329220A1|2014-11-06|
    JP6293747B2|2018-03-14|
    JP2015524393A|2015-08-24|
    WO2014011539A2|2014-01-16|
    US20140017660A1|2014-01-16|
    WO2014011539A3|2014-03-13|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US1566653A|1925-12-22|Gate and clamping device for wire-line clamps |
    US1339419A|1919-05-08|1920-05-11|Philip M Rea|Wire-line clamp|
    US1339420A|1920-02-13|1920-05-11|Philip M Rea|Liner for wire-line clamps|
    US2262162A|1940-01-16|1941-11-11|Louis H Bock|Wire clamp|
    US3709526A|1971-03-01|1973-01-09|Baxter Laboratories Inc|Multiple piece clamp for connecting tubing|
    US4389034A|1980-07-21|1983-06-21|Anchoring International, Inc.|Underwater pipe anchoring device|
    US4437791A|1982-04-02|1984-03-20|Reynolds Graeme E|Clamp for hydraulic hose bundles|
    CN2114426U|1991-12-16|1992-09-02|任秀玲|Arresting bleeding umbillical cord clamps|
    US5571125A|1995-08-07|1996-11-05|Chadwick; Dale A.|Penis-clamping device for the incontinent|
    US5582082A|1995-08-10|1996-12-10|Gajo; Alden H.|Open-end wrench having self-contained ratcheting mechanism allowing one-way rotational driving of a hardware element|
    US5728115A|1995-12-29|1998-03-17|Indiana University Foundation|Perfusion clamp|
    US6977140B1|1998-09-29|2005-12-20|Organ Recovery Systems, Inc.|Method for maintaining and/or restoring viability of organs|
    EP2441395A3|2000-11-28|2014-06-18|Intuitive Surgical Operations, Inc.|Endoscope beating-heart stabilizer and vessel occlusion fastener|
    GB0107708D0|2001-03-28|2001-05-16|Imp College Innovations Ltd|Bone fixated,articulated joint load control device|
    US7588585B2|2002-03-26|2009-09-15|Novare Surgical Systems, Inc.|Handleless clamping device|
    DE60314154T2|2002-08-23|2008-01-24|Organ Recovery Systems, Des Plaines|CONNECTION ARRANGEMENTS, ESPECIALLY FOR TRANSPLANT ORGANS|
    US6871570B1|2003-05-03|2005-03-29|Richard Santillan|Ratchet wrench with nut-gripping clip|
    US6899262B2|2003-05-19|2005-05-31|Asm Technology Singapore Pte Ltd|Clamping device|
    US20060217746A1|2005-03-24|2006-09-28|Krolman Arthur M|Renal perfusion clamp|
    US7559525B2|2005-11-07|2009-07-14|Grimes Dennis L|Clamp device for temporarily closing flexible pipes without pipe wall damage|
    US8474784B2|2006-04-05|2013-07-02|Noble House Group Pty. Ltd.|Non-reopening locking pinch clamp for tubing|
    US7922746B2|2006-08-31|2011-04-12|Warsaw Orthopedic, Inc.|Spinal rod extenders and methods of use|
    US7736371B2|2007-01-26|2010-06-15|Stryker Leibinger Gmbh & Co. Kg|Trajectory guide|
    FR2920513B1|2007-09-04|2021-05-28|Fresenius Vial|CLAMP FOR SOFT TUBING, PUMP EQUIPPED WITH MEANS FOR OPENING SUCH CLAMP AND INFUSION SET EQUIPPED WITH SUCH CLAMP.|
    US8105362B2|2008-06-30|2012-01-31|Duarte Luis E|Percutaneous spinal rod insertion system and related methods|
    US8382474B2|2008-12-31|2013-02-26|Cadent Ltd.|Dental articulator|
    GB2477549A|2010-02-05|2011-08-10|Clare Margaret Byam-Cook|A pair of forceps for assisting with breastfeeding|
    US8679160B2|2010-09-28|2014-03-25|Facet-Link Inc.|Lamina implant set|
    EP2460483B1|2010-12-03|2013-06-26|Zimmer Spine|Surgical instrument|
    US8828034B2|2011-04-29|2014-09-09|Lifeline Scientific, Inc.|Cannula|
    US9642625B2|2011-04-29|2017-05-09|Lifeline Scientific, Inc.|Cannula for a donor organ with or without an aortic cuff or patch|
    US9022978B2|2011-04-29|2015-05-05|Lifeline Scientific, Inc.|Universal sealring cannula|US8409846B2|1997-09-23|2013-04-02|The United States Of America As Represented By The Department Of Veteran Affairs|Compositions, methods and devices for maintaining an organ|
    US10543671B2|2010-08-09|2020-01-28|Decopac, Inc.|Three-dimensional decorating system for edible items|
    US8304181B2|2004-10-07|2012-11-06|Transmedics, Inc.|Method for ex-vivo organ care and for using lactate as an indication of donor organ status|
    US9215867B2|2004-10-07|2015-12-22|Transmedics, Inc.|Systems and methods for ex-vivo organ care|
    US9078428B2|2005-06-28|2015-07-14|Transmedics, Inc.|Systems, methods, compositions and solutions for perfusing an organ|
    US9457179B2|2007-03-20|2016-10-04|Transmedics, Inc.|Systems for monitoring and applying electrical currents in an organ perfusion system|
    US10750738B2|2008-01-31|2020-08-25|Transmedics, Inc.|Systems and methods for ex vivo lung care|
    US20130245653A1|2012-03-19|2013-09-19|Craig Michael Litherland|Zero artifact vascular clip method and apparatus|
    US9826452B2|2014-04-14|2017-11-21|Mediatek Inc.|Apparatuses and methods for access domain selectionduring an inter-radio access technologyprocedure|
    JP2017518301A|2014-06-02|2017-07-06|トランスメディクス， インク．Ｔｒａｎｓｍｅｄｉｃｓ， Ｉｎｃ．|Ex-vivo organ management system|
    EP3824731A1|2015-09-09|2021-05-26|Transmedics, Inc.|Aortic cannula for ex vivo organ care system|
    EP3576809A1|2017-02-06|2019-12-11|Sanofi-Aventis Deutschland GmbH|Assembly nest for a pen injection device with locking function|
    WO2018180544A1|2017-03-30|2018-10-04|国立大学法人北見工業大学|Connector and fluid supply system|
    法律状态:
    2018-03-06| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2018-03-13| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2018-03-20| B06I| Publication of requirement cancelled [chapter 6.9 patent gazette]|Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
    2020-12-08| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
    2021-07-27| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
    2021-09-14| B16A| Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/07/2013, OBSERVADAS AS CONDICOES LEGAIS. |
    优先权:
    申请号 | 申请日 | 专利标题
    US13/545,185|US8814889B2|2012-07-10|2012-07-10|Cannula with floating clamp member|
    US13/545,185|2012-07-10|
    PCT/US2013/049564|WO2014011539A2|2012-07-10|2013-07-08|Cannula with floating clamping member|
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