 surgical instrument apparatus
专利摘要:
ABSTRACT A surgical instrument includes a handle portion, a shaft housing a firing bar, an end effector comprising an anvil, a lower jaw, and a stapling and severing assembly responsive to a longitudinal closing motion produced by the handle portion and the shaft. The lower jaw is configured to receive a removable cartridge. The cartridge includes a housing, a plurality of staples in the housing, and a deck plus the plurality of staples. The deck defines, with each aperture being apertures with each aperture being over each staple. The cartridge further includes an agent. The firing bar is operable to assist with releasing the agent onto the severed line of tissue when the firing bar is advanced. ************************** SURGICAL STAPLING DEVICE WITH AUXILIARY MATERIAL APPLICATION FEATURE. The present invention relates to a surgical instrument that includes a handle portion, a rod that houses a trigger bar, and an end actuator that comprises an anvil, a lower jaw, and a clamping and separating assembly responsive to a longitudinal closing movement produced by the handle portion and the rod. The lower jaw is configured to receive a removable cartridge. The cartridge includes a slot,(...). 公开号:BR112014007004B1 申请号:R112014007004-0 申请日:2012-09-19 公开日:2021-05-04 发明作者:Chad P. Boudreaux；Stephen J. Balek；Matthew D. Holcomb；Edward A. Rhad；Matthew C. Miller；Thomas W. Lytle Iv；Charles J. Scheib；Bret W. Smith；Yi-Lan Wang；Donald F. Wilson, Jr.；Kreena R. Modi；Joseph Zavatsky；Aron O. Zingman 申请人:Ethicon Endo-Surgery, Inc； IPC主号:
专利说明:
BACKGROUND [001] In some contexts, endoscopic surgical instruments may be preferred over devices for traditional open surgery, as a smaller incision can reduce recovery time and complications in the postoperative period. Consequently, some endoscopic surgical instruments may be suitable for placing a distal end actuator at a desired surgical site via a trocar cannula. These distal end actuators can secure tissue in a variety of ways to achieve a diagnostic or therapeutic effect (eg, endocutter, gripper, cutter, stapler, clip applicator, access device, pharmacological/genetic therapy delivery device, and device for application of energy using ultrasound, RF, laser etc.). Endoscopic surgical instruments may comprise a rod between the end actuator and a handle portion, which is manipulated by the physician. This rod can allow insertion to the desired depth and rotation around the longitudinal axis of the rod itself, thus facilitating the positioning of the end actuator on the patient. Positioning an end actuator can also be facilitated by the inclusion of one or more swivel joints or components, allowing the end actuator to be selectively swiveled or even offset with respect to the longitudinal axis of the stem. [002] Examples of endoscopic surgical instruments include surgical staplers. Some of these staplers are operated to staple fabric layers, cut through stapled fabric layers, and drive staples through fabric layers to securely join the sectioned fabric layers near the sectioned ends of the fabric layers. Merely exemplary surgical staplers are revealed; US Patent No. 4,805,823 entitled "Pocket Configuration for Internal Organ Staplers", issued February 21, 1989; U.S. Patent No. 5,415,334 entitled "Surgical Stapler and Staple Cartridge", issued May 16, 1995; U.S. Patent No. 5,465,895 entitled "Surgical Stapler Instrument", issued November 14, 1995; US Patent No. 5,597,107 entitled "Surgical Stapler Instrument", issued January 28, 1997; US Patent No. 5,632,432 entitled "Surgical Instrument", issued May 27, 1997; US Patent No. 5,673,840 entitled "Surgical Instrument", issued October 7, 1997; US Patent No. 5,704,534 entitled "Articulation Assembly for Surgical Instruments", issued January 6, 1998; US Patent No. 5,814,055 entitled "Surgical Clamping Mechanism", issued September 29, 1998; US Patent No. 6,964,363 entitled "Surgical Stapling Instrument having Articulation Joint Support Plates for Supporting a Firing Bar", granted on November 15, 2005; US Patent No. 6,978,921 entitled "Surgical Stapling Instrument Incorporating an E-Beam Firing Mechanism", issued December 27, 2005; US Patent No. 6,988,649 entitled "Surgical Stapling Instrument Having a Spent Cartridge Lockout", issued January 24, 2006; U.S. Patent No. 7,000,818 entitled "Surgical Stapling Instrument Having Separate Distinct Closing and Firing Systems", issued February 21, 2006; US Patent No. 7,111,769 entitled "Surgical Instrument Incorporating an Articulation Mechanism having Rotation about the Longitudinal Axis", issued September 26, 2006; U.S. Patent No. 7,143,923 entitled "Surgical Stapling Instrument Having a Firing Lockout for an Unclosed Anvil", issued December 5, 2006; US Patent No. 7,303,108 entitled "Surgical Stapling Instrument Incorporating a Multi-Stroke Firing Mechanism with a Flexible Rack", issued December 4, 2007; US Patent No. 7,367,485 entitled "Surgical Stapling Instrument Incorporating a Multistroke Firing Mechanism Having a Rotary Transmission", issued May 6, 2008; US Patent No. 7,380,695 entitled "Surgical Stapling Instrument Having a Single Lockout Mechanism for Prevention of Firing", granted June 3, 2008; US Patent No. 7,380,696 entitled "Articulating Surgical Stapling Instrument Incorporating a Two-Piece E-Beam Firing Mechanism", granted June 3, 2008; US Patent No. 7,404,508 entitled "Surgical Stapling and Cutting Device", issued July 29, 2008; U.S. Patent No. 7,434,715 entitled "Surgical Stapling Instrument Having Multiple Strokes of Firing with Aperture Lock", granted on October 14, 2008; US Patent No. 7,721,930 entitled "Disposable Cartridge with Adhesive for Use with a Stapling Device", issued May 25, 2010; and US Patent No. 7,455,208 entitled "Surgical Instrument with Articulating Shaft with Rigid Firing Bar Supports", issued November 25, 2008. The description of each of the above-cited US patents is incorporated by reference into the present invention. Although the aforementioned surgical staplers are described as being used in endoscopic procedures, it should be understood that these surgical staplers can also be used in open procedures and/or other non-endoscopic procedures. [003] Although various types of surgical stapling instruments and associated components have been manufactured and used, it is believed that no one prior to the inventor(s) has manufactured or used the invention described in the appended claims. BRIEF DESCRIPTION OF THE DRAWINGS [004] The attached drawings, which are incorporated into and form part of this descriptive report, illustrate embodiments of the invention and, together with the general description provided above and the detailed description of the embodiments provided below, serve to explain the principles of present invention. [005] FIG. 1A shows a perspective view of an articulating surgical instrument with an end actuator in an unhinged position; [006] FIG. 1B shows a perspective view of the surgical instrument of FIG. 1A with an end actuator in a pivoted position; [007] FIG. 2 shows a perspective view of the open-end actuator of the surgical instrument of FIGS. 1A to 1B; [008] FIG. 3A shows a side cross-sectional view of the end actuator of FIG. 2, taken along line 3-3 of FIG. 2, with the trigger bar in a proximal position; [009] FIG. 3B shows a side cross-sectional view of the end actuator of FIG. 2, taken along line 3-3 of FIG. 2, but showing the trigger bar in a distal position; [0010] FIG. 4 shows a cross-sectional view from the end of the end actuator of FIG. 2, taken along line 4-4 of FIG. two; [0011] FIG. 5 shows an exploded perspective view of the end actuator of FIG. two; [0012] FIG. 6 shows a perspective view of the end actuator of FIG. 2, positioned on the fabric that was actuated once on the fabric; [0013] FIG. 7 shows a plan view of an exemplary removable cartridge version of the end actuator of FIG. 2 and an exemplary trigger bar with an auxiliary material connected to the trigger bar, with the trigger bar in a first position; [0014] FIG. 8 shows a plan view of the cartridge of FIG. 7 with the trigger bar in a second position; [0015] FIG. 9 shows an exploded perspective view of the auxiliary material of FIG. 7 captured in a notch at the top of the trigger bar in FIG. 7; [0016] FIG. 10 shows a plan view of an exemplary alternative version of a removable cartridge of the end actuator of FIG. 2 and an exemplary trigger bar with an auxiliary material connected to the trigger bar, with the trigger bar in a first position; [0017] FIG. 11 shows a plan view of yet another exemplary alternative version of a removable cartridge of the end actuator of FIG. 2 and an exemplary trigger bar with an auxiliary material connected to the trigger bar, with the trigger bar in a first position; [0018] FIG. 12 shows an exploded perspective view of the auxiliary material of FIG. 10 or FIG. 11 connected to an exemplary fire bar through an elongated side notch in the fire bar; [0019] FIG. 13 shows a perspective view of another exemplary removable cartridge of the end actuator of FIG. 2 and an exemplary firing bar with an auxiliary material being deposited on the firing bar through a first version of an auxiliary applicator, with the firing bar being fired through the cartridge; [0020] FIG. 14 shows an exploded perspective view of a second alternative version of an auxiliary applicator for the cartridge of FIG. 13; [0021] FIG. 15 shows an exploded perspective view of a third alternative version of an auxiliary applicator for the cartridge of FIG. 13; and [0022] FIG. 16 shows a cross-sectional view of auxiliary material deposited as a tissue repair composition on the sectioned tissue. [0023] The drawings are not intended to be limiting in any way, and it is contemplated that various embodiments of the invention may be carried out in a variety of other ways, including those not necessarily represented in the drawings. The accompanying drawings incorporated and forming a part of the descriptive report illustrate various aspects of the present invention, and together with the description serve to explain the principles of the invention; it is understood, however, that this invention is not limited to the arrangements shown. DETAILED DESCRIPTION [0024] The following description of specific examples of the invention should not be used to limit the scope of the present invention. Other examples, features, aspects, modalities and advantages of the invention will become apparent to those skilled in the art from the following description, which uses illustrations, one of the best contemplated modes for carrying out the invention. As will be understood, the invention may have other different and obvious aspects, all without departing from the invention. Consequently, the drawings and descriptions are to be regarded as illustrative in nature and not restrictive. Exemplary surgical stapler [0025] FIGS. 1-6 depict an exemplary surgical stapling and sectioning instrument (10) that is sized for insertion in an unarticulated state, as depicted in FIG. 1A, through a trocar cannula conduit, to a surgical site in a patient undergoing a surgical procedure. The surgical stapling and sectioning instrument (10) includes the handle portion (20) connected to the implement portion (22), the latter further comprising the rod (23) in a distal position ending in an articulation mechanism ( 11) and a fixed end actuator (12) in a distal position. When the pivot mechanism (11) and end actuator (12) are inserted through the cannula passage of a trocar, the pivot mechanism (11) can be remotely pivoted as shown in FIG. 1B, by the articulation control (13). Thus, the end actuator (12) can reach behind an organ or approach tissue at a desired angle or for other reasons. It should be understood that terms such as "proximal" and "distal" are used in the present invention with reference to the handle portion (20) of the instrument (10) manipulated by the physician. In this way, the end actuator (12) is distal with respect to the most proximal cable portion (20). It will further be recognized that, for convenience and clarity, spatial terms such as "vertical" and "horizontal" are used in the present invention in relation to the drawings. However, surgical instruments can be used in many orientations and positions, and these terms are not intended to be limiting and absolute. [0026] End actuator (12) of the present example includes a lower jaw (16) and a hinged anvil (18). The handle portion (20) includes a pistol grip (24), against which a closing actuator (26) is pivotally pressed by the physician in order to pinch or close the anvil (18) against the lower jaw ( 16) of the end actuator (12). This closing of the anvil (18) is achieved by means of an external closing sleeve (32), which translates longitudinally in relation to the cable portion (20) in response to the articulated actuation of the closing actuator (26) against the handle pistol (24). A distal closure ring (33) of the closure sleeve (32) is indirectly supported by the frame (34) of the implement portion (22). In the hinge mechanism (11), a closure tube (35) proximal to the closure sleeve (32) communicates with the distal closure ring (33). The frame (34) is flexibly connected to the lower jaw (16) via the articulation mechanism (11), allowing articulation in a single plane. The frame (34) also longitudinally and slidingly supports a firing trigger member (not shown) which extends through the rod (23) and transmits firing motion from the firing trigger (28) to the firing bar. shot (14). The firing trigger (28) is furthest away from the closing trigger (26), being pivotally pressed by the physician to staple and section the tissue clamped on the end actuator (12), as will be described in more detail below. Then, the release button (30) is released to release the tissue from the end actuator (12). [0027] FIGS. 2-5 depict the end actuator (12) employing an electronic beam firing bar (14) to perform a variety of functions. As best seen in FIGS. 3A and 3B, the trigger bar (14) includes a transversely oriented top pin (38), a trigger bar cap (44), a transversely oriented middle pin (46) and a distally oriented cutting edge (48). The top pin (38) is located and is translatable within an anvil pocket (40) of the anvil (18). The trigger bar cap (44) slidingly engages the lower surface of the lower jaw (16), causing the trigger bar (14) to extend along the slot of the channel (45) (shown in FIG. 3B) which is formed along the lower jaw (16). The middle pin (46) slidingly engages the top surface of the lower jaw (16), cooperating with the trigger bar cap (44). In this way, the firing bar (14) affirmatively spaces the end actuator (12) during firing, avoiding mechanical pinching that can occur between the anvil (18) and the lower jaw (16) with a minimal amount of pinched tissue and preventing bad staple formation when an excessive amount of tissue is clamped. [0028] FIG. 2 shows the trigger bar (14) proximally positioned and the anvil (18) hinged in an open position, allowing an unused staple cartridge (37) to be removably installed in the lower jaw channel (16). As best seen in FIGS. 4 and 5, the staple cartridge (37) of this example includes a cartridge body (70), which contains an upper platform (72), and is coupled to a lower cartridge tray (74). As best seen in FIG. 2, a vertical slit (49) is formed through part of the staple cartridge (37). As is also best seen in FIG. 2, three rows of clip openings (51) are formed through the top platform (72) on one side of the vertical slot (49) with another set of three rows of clip openings (51) being formed through the top platform (72 ) on the other side of the vertical slot (49). Returning to FIGS. 3-5, a wedge-shaped slider support (41) and a plurality of clamp drivers (43) are captured between the cartridge body (70) and the tray (74), with the wedge-shaped slider support ( 41) located proximal to the staple drivers (43). The wedge-shaped slide holder (41) is movable longitudinally within the staple cartridge (37); while the staple drivers (43) are movable vertically within the staple cartridge (37). The staples (47) are also positioned within the cartridge body (70), above the corresponding staple drivers (43). In particular, each clamp (47) is driven vertically within the cartridge body (70) by a staple driver (43) so as to drive the staple (47) through an associated staple opening (51). As best seen in FIGS. 3A and 3B and 5, the wedge-shaped slider bracket (41) has slanted cam surfaces that push the staple drivers (43) upward as the wedge slider bracket (41) is driven distally through the cartridge. of staples (37). [0029] With the end actuator (12) closed, as shown in FIG. 3A, the trigger bar (14) is advanced in engagement with the anvil (18) by entering the top pin (38) into a longitudinal slot of the anvil (42). A drive block (80) is located at the distal end of the trigger bar (14) and is configured to engage the wedge slide support (41) so that the wedge slide support (41) is pushed. distally by the drive block (80) as the trigger bar (14) is advanced distally through a staple cartridge (37). During this firing, the cutting edge (48) of the firing bar (14) enters the vertical slot (49) of the staple cartridge (37), severing the clamped tissue between the staple cartridge (37) and the anvil (18) . As shown in FIGS. 3A and 3B, the middle pin (46) and the drive block (80) together drive the staple cartridge (37) into the slot (49) in the staple cartridge (37), driving the wedge-shaped slide holder (41) into the ascending cam in contact with the clamp drivers (43) which in turn drive the clamps (47) out through the clamp openings (51) and making contact with the clamp-shaped pockets (53 ) on the inner surface of the anvil (18). FIG. 3B depicts the trigger bar (14) completely distally translated after tissue sectioning and stapling is complete. [0030] FIG. 6 shows end actuator (12) actuated by a single movement through fabric (90). The cutting edge (48) has the fabric cut (90), while the staple drivers (43) drive three alternating rows of staples (47) through the fabric (90) on each side of the cut line produced by the cutting edge (48 ). The clamps (47) are all oriented substantially parallel to the cut line in this example, although it should be understood that the clamps (47) can be positioned in any suitable orientations. In the present example, the end actuator (12) is removed from the trocar after the first stroke is completed, the used staple cartridge (37) is replaced with a new staple cartridge, and the end actuator (12) is again inserted through the trocar to reach the stapling location for additional cutting and stapling. This process can be repeated until the desired amount of cuts and staples (47) has been applied. The incus (18) may need to be closed to facilitate insertion and removal through the trocar; and the anvil (18) may need to be opened to facilitate replacement of the staple cartridge (37). [0031] It should be understood that the cutting edge (48) can section tissue at substantially the same time as the clamps (47) are driven through the tissue during each stroke of actuation. In the present example, the cutting edge (48) closely follows the insertion of the staples (47), so that a staple (47) is pushed through the tissue just before the cutting edge (48) passes through the same region of the tissue, although it should be understood that this order can be reversed, or that the cutting edge (48) can be directly synchronized with the adjacent clamps. Although FIG. 6 show the end actuator (12) being actuated in two layers (92 and 94) of fabric (90), it should be understood that the end actuator (12) can be actuated through a single layer of fabric (90) or more than two layers (92 and 94) of fabric. It should also be understood that the formation and positioning of staples (47) adjacent to the cut line produced by the cutting edge (48) can substantially bind tissue together at the cut line, thus reducing or preventing bleeding and/or leakage of other bodily fluids in the cut line. Various suitable configurations and procedures in which instrument 10 can be used will be apparent to those skilled in the art in view of the teachings contained herein. [0032] It should be understood that the instrument (10) is configurable and operable in accordance with any other teachings of US Patent No. 4,805,823; US Patent No. 5,415,334; US Patent No. 5,465,895; US Patent No. 5,597,107; US Patent No. 5,632,432; US Patent No. 5,673,840; US Patent No. 5,704,534; US Patent No. 5,814,055; US Patent No. 6,978,921; US Patent No. 7,000,818; US Patent No. 7,143,923; US Patent No. 7,303,108; US Patent No. 7,367,485; US Patent No. 7,380,695; US Patent No. 7,380,696; US Patent No. 7,404,508; US Patent No. 7,434,715; and/or US Patent No. 7,721,930. [0033] As noted above, the descriptions of each of these patents are incorporated by reference to the present invention. Additional exemplary modifications that can be made to the instrument (10) will be described in more detail below. Various suitable ways in which the teachings below can be incorporated into instrument (10) will be apparent to those skilled in the art. Similarly, various ways in which the teachings below can be combined with the various teachings of the patents cited herein will be apparent to those skilled in the art. It is also to be understood that the teachings below are not limited to the instrument (10) or devices taught in the patents cited herein. The teachings below can be readily applied to many other types of instruments, including instruments that would not be classified as surgical staplers. Various other suitable devices and configurations in which the teachings below can be applied will be apparent to those skilled in the art in view of the teachings contained herein. Exemplary trigger bar and cartridge assembly for depositing auxiliary material [0034] Examples described below include the exemplary firing bar and cartridge assemblies operable to deposit auxiliary material on the fabric while the firing bar severs the fabric and while the staples are driven from the cartridge to the fabric. The auxiliary material can comprise, for example, the auxiliary compound or hemostatic agents such as fibrin or thrombin which aid in blood clotting and reduce the amount of bleeding at the surgical site. The hemostatic capabilities of these auxiliary compounds may also contribute to the use of these auxiliary compounds as adhesives and sealants. The agents can, for example, substantially prevent leakage across the location of the stapled fabric. Such auxiliary compounds or reagents may also include, but are not limited to, medical fluid or support components such as platelet-poor plasma (PPP), platelet-rich plasma (PRP), starch, chitosan, alginate, fibrin, polysaccharide, cellulose , collagen, bovine collagen, gelatin-based adhesive, resorcin and formalin, oxidized cellulose, mussel-based adhesive, poly amino acid, agarose, amylose, hyaluronan, poly (hydroxy butyrate) (PHB), hyaluronic acid, polyvinylpyrrolidone (PVP) , poly(vinyl alcohol) (PVA), polylactide (PLA), polyglycolide (PGA), polycaprolactone (PCL), and their copolymers, VICRYL® (Ethicon, Inc., Somerville, NJ, USA), MONOCRYL material, PANACRYL ( Ethicon, Inc., Somerville, NJ, USA), and/or any other material suitable to be mixed with biological material and introduced into an injured or defective location, including combinations of materials. For example, the material can be selected from the following materials: epsilon-caprolactone glycolide, bovine pericardium, alkyd resins, polyglycolic acid, polyglactin, polydioxanone, polyglyconate, whey protein, cellulose gum, starch, gelatin, silk , nylon, polypropylene, woven polyester, polybutester, polyethylene, and/or polyether ether ketones. Other suitable compounds, materials, substances etc that can be used in a medical fluid or carrier will be apparent to those skilled in the art in view of the teachings in the present invention. Suitable auxiliary compounds or reagents may also include, but are not limited to, medical fluid or carrier components, including, but not limited to, natural or genetically modified absorbable polymers or synthetic absorbable polymers, or mixtures thereof. Examples of natural or genetically modified polymers are proteins, polysaccharides and combinations thereof. Proteins include, prothrombin, thrombin, fibrinogen, fibrin, fibronectin, heparinase, Factor X/Xa, Factor VII/VIla, Factor IX/IXa, Factor XI/XIa, Factor XII/XIIa, tissue factor, batroxobin, ancrodo, ecarine, Von Willebrand factor, collagen, elastin, albumin, gelatin, platelet surface glycoproteins, vasopressin, vasopressin analogue, epinephrine, selectin, procoagulant poison, plasminogen activator inhibitor, platelet activating agents, hemostatic activity with synthetic peptides, and/ or combinations thereof. Polysaccharides include, but are not limited to, cellulose, alkyl cellulose, for example, methyl cellulose, alkyl hydroxy alkyl cellulose, hydroxy alkyl cellulose, cellulose sulfate, carboxy methyl cellulose salts, carboxy methyl cellulose, carboxy ethyl cellulose, chitin, carboxy methyl chitin, hyaluronic acid, hyaluronic acid salts, alginate, alginic acid, propylene glycol alginate, glycogen, dextran, dextran sulfate, curdlan, pectin, pullulan, xanthan, chondroitin, chondroitin sulfates, carboxy methyl dextran, carboxy methyl chitos chitosan, heparin, heparin sulfate, heparan, heparan sulfate, dermatan sulfate, keratan sulfate, carrageenans, chitosan, starch, amylose, amylopectin, poly-N-glucosamine, polymanuronic acid, polyglucuronic acid, polyguluronic acid, and derivatives of any of these. Examples of synthetic absorbable polymers are aliphatic polyester polymers, copolymers, and/or combinations thereof. Aliphatic polyesters are typically synthesized in a ring opening polymerization of monomers that include, but are not limited to, lactic acid, lactide (L-, D-, meso and mixtures of D and L), glycolic acid, glycolide, ε -caprolactone, p-dioxanone (1,4-dioxan-2-one) and trimethylene carbonate (1,3-dioxan-2-one). [0036] In some versions, a medical fluid may be suspended in a biocompatible conductor to form the auxiliary compound material. Suitable vehicles can include, for example, a physiological buffer solution, a high-flow gel solution, saline and water. In the case of gel solutions, the tissue repair composition can be in a high-flow gel form before delivery to the target site, or it can form a gel and remain in place after delivery to the target site. High flow gel solutions can comprise one or more gelling materials with or without the addition of water, saline, or physiological buffer solution. Suitable gelling materials include biological and synthetic materials. Exemplary gelling materials include proteins, polysaccharides, polynucleotides, and other materials such as alginate, cross-linked alginate, poly(N-isopropyl acrylamide), poly(oxyalkylene), poly(ethylene oxide)-poly(propylene oxide), poly( vinyl alcohol), polyacrylate, or monostearoyl glycerol/polyethylene glycol (MGSA/PEG) co-succinate copolymers, and combinations of any of the above. [0037] material may further be retained in and/or comprise a fibrous pad, a foam, a matrix, a mesh mesh or other structure, in accordance with the teachings of, by way of example, published US patent application under No. 2009/0120994, entitled "Surgical Fastening Device with Initiator Impregnation of a Matrix or Buttress to Improve Adhesive Application", published on May 14, 2009, the description which is incorporated by reference into the present invention. The material may comprise, for example, a biocompatible material that is a support, a matrix with a plurality of openings therein, an open cell or closed cell foam, and/or a tissue pad. The material may include porosities that induce a capillary absorption characteristic to drive the adhesive into the material and ensure that the openings remain free of adhesive, allowing tissue growth through the openings after application to the tissue. [0038] Additionally or alternatively, the auxiliary material can be comprised of an adhesive such as, but not limited to, polymerizable and/or crosslinkable materials such as a cyanoacrylate-based adhesive. The adhesive, for example, can be a monomeric (including prepolymer) adhesive composition, a polymeric adhesive composition, or any other compound that can adhere to the fabric. In embodiments, the monomer can be a 1,1-disubstituted ethylene monomer, for example, an alphacyanoacrylate. When cross-linked or polymerized, cyanoacrylate can change from a liquid to a solid. Polymerized adhesives, for example, can be formulated to be flexible to rigid and can be spongy. If desired, the adhesive may be a single or double piece adhesive, and/or may contain additives as alternative compounds. Adhesive polymerization can occur from, but is not limited to, exposure to moisture, heat and/or adhesion initiators such as those described in US patent application published under No. 2009/0120994, the description which is incorporated above by reference. Other suitable materials and compositions that can be used will be apparent to those skilled in the art in view of the teachings in the present invention. Top notch in the shooting bar version [0039] FIGS. 7 and 8 show a removable cartridge (101) that includes components similar to the cartridge (37) described above. The cartridge (101) includes the material (114) in tape form and is disposed over the exemplary firing bar (103) in the lower jaw (16) of the end actuator (12) described above. The firing bar (103) is similar to the firing bar (14) described above. FIG. 9 shows the firing bar (103) as including a distally positioned blade (100) with a top surface (102) ending in an upper tip (104). The firing bar (103) also includes an elongated proximal portion (106) extending from the distally positioned blade (100). The upper edge (108) of the elongated proximal portion (106) includes the notch (110). The notch (110) is configured to receive the intermediate portion (112) of the material (114) disposed between and connecting the first and second spools (116 and 118) of the material (114). The spools (116 and 118) of the material (114) can be resiliently pulled to prevent premature unwinding of the material (114) from the spools (116 and 118). [0040] material (114) can be comprised of a hemostatic agent and/or various other materials as described above. As the trigger bar (103) moves distally in the direction of the arrow (A) through the vertical slot (99) defined in the upper platform (105) of the cartridge (101), the trigger bar (103) holds and drags the material (114) distally forward while unwinding material (114) from spools (116 and 118), as shown in FIG. 8. The firing bar (103) at the end releases the material (114) on the tissue sectioned by the blade (100). Additionally or alternatively, a wedge-shaped sliding support, similar to the wedge-shaped sliding support (41) described above, can attach to the material (114) and pull the material (114) distally forward as the trigger bar (103) is advanced distally. [0041] The fabric is sectioned by the firing bar (103) in a similar manner to how the firing bar (14) sections the fabric, as described above. The upper edge (108) is disposed above the upper surfaces of the coils (116 and 118) so that when the material (114) is driven forward by the firing bar (103), the layers of material (114) in any side of the firing bar (103) will not contact each other and stick. [0042] Cartridge (101) includes first and second knives (120 and 122) disposed at the distal end (124) of the slit (99). As the trigger bar (103) fires distally past the knives (120 and 122), the knives (120 and 122) cut through the material (114) allowing the intermediate portion (112) of the material (114) to be removed from the notch (110) of the firing bar (103). This causes the trigger bar (103) to return to an original position as shown in FIG. 7, without retaining a substantial portion of material (114). After the cartridge (101) is used, a user can reload a new cartridge and repeat the process described above. B. Side notch on release bar versions [0043] FIGS. 10 and 11 show other exemplary cartridges (107 and 113) that are configured to receive in the lower jaw (16). The cartridges (107 and 113) further include portions for receiving a firing bar (126) which is similar in operation to the firing bar (14) described above with respect to the cartridge (37). Referring to FIG. 12, the firing bar (126) includes the distally positioned blade (128) that terminates in the upper tip (130). An elongated side notch (136) is disposed below the top edge (132) and over or even opposite sides (134) of the trigger bar (126), and is configured to receive material (138) when the exemplary cartridges ( 107 and 113) are arranged on the firing bar (126) in a first position, and as described below. Coil version [0044] FIG. 10 shows the cartridge (107) including the material (138) in tape form as part of the first and second plurality of spools (140 and 142) disposed below the platform (109). When the cartridge (107) is inserted into the lower jaw (16), the material (138) of the inner ends of the spools (140 and 142) affixes to the sides (134) of the firing bar (126) through the notch (136) . For example, the cartridge (107) can be inserted into a lower jaw (16) at an angle sufficient to allow material (138) passing between the spools (140 and 142) to pass under the trigger bar (126) and into the inside of the notch (136). Such material (138) can then be retained in the notch (136) as the cartridge (107) is press-fitted into place. Alternatively, the upper edge (132) may include a slit that communicates with the notch (136), enabling material (138) to enter the notch (136) from the upper side of the firing bar (126). In either case, when the firing bar (126) is distally fired in the direction of arrow (B), the material (138) of the coils (140 and 142) is unwound and distally fired together with the firing bar (126) until the firing bar (126) reaches the knives (144, 146) at the distal end (148) of the slot (111) of the platform (109). The slit (111) is similar in structure and operation to the slit (49) described above. The knives (144 and 146) then act to section the material (138) from the sides (134) of the fire bar (126) so that the fire bar (126) can return to its original position without holding back. a substantial portion of material (138). Additionally, material (138) will be released into the sectioned portion of the tissue (90) when the trigger bar (126) severs the tissue (90) in a similar way as the trigger bar (14) severs the tissue (90) , as described above. [0045] FIG. 16 shows an example of material (138) released at the sectioned edges of fabric (90) that has been stapled with staples (47) from the end actuator (12). In particular, the sectioned edges of the fabric (90) form a cut line (160). The material (138) is shown as deposited onto the fabric (90) on either side of the cut line (160), which is a line substantially aligned with the slot (111) of the cartridge (107) when the end actuator ( 12), including the cartridge (107), operates to section the tissue (90) with the firing bar (126). It should be understood that use of the various other examples of auxiliary material described herein can produce results similar to those shown in FIG. 16. 2. Surrounding version [0046] FIG. 11 shows the cartridge (113) with tapes of material (138) that include the surrounding portions (150). The surrounding portions (150) movably surround the outer periphery of the platform (115) of the cartridge (113). When the cartridge (113) is inserted into the lower jaw (16), material (138) from the intermediate portion (152) of the surrounding portion (150) is inserted into the notch (136) of the firing bar (126). When the firing bar (126) is fired distally in the direction of the arrow (C) along the slit (117), which is similar to the slit (111) described above, the material (138) of the surrounding portion (150) is trapped. and fired distally along with the firing bar (126), dragging material from the surrounding portion (150) in the direction of the arrow (D) until the firing bar (126) reaches the knives (154 and 156) at the distal end ( 158) of the slot (111) of the platform (109). The knives (154 and 156) section the material (138) from the firing bar (126) in a similar manner to the knives (144 and 146) of the cartridge (107) described above. Similarly, material (138) will be released into the sectioned portion of the tissue (90) when the trigger bar (126) severs the tissue (90). C. Knife slot version [0047] FIG. 13 shows another exemplary cartridge (119), which is similar to the cartridge (37) described above, except as set forth below. The cartridge (119) includes an auxiliary applicator configured to dispose a hemostatic material or auxiliary compound and/or any other suitable material onto a trigger bar (162). The firing bar (162) of this example includes a series of notches (164) along a portion of its length on opposite sides (166). Various examples of auxiliary compound applicators that cooperate with the notches (164) will be described below, while other examples will be apparent to those skilled in the art in view of the teachings in the present invention. It should be understood that the notches (164) may comprise recesses which do not pass completely from one side (166) to the other side (166). Additionally or alternatively, the notches (164) may comprise openings providing complete passage from one side (166) to the other side (166). Cylinder Version [0048] cartridge (119) may include a first version of the auxiliary applicator (168). FIG. 13 shows the applicator (168) comprising cylinders (170 and 172) configured to be rotatably abutting opposite sides (166) of the firing bar (162). When the trigger bar (162) is distally advanced in the direction of the arrow (E) through the vertical slot (121) of the cartridge (119), the leading edge (167) of the trigger bar (162) can section the material (174 ) between the cylinders (170 and 172). Alternatively, the firing bar (162) can simply pass along the cylinders (170 and 172) without sectioning anything between the ball applicators (170 and 172). As the trigger bar (162) continues to advance distally, the material (174) will roll and coat the sides (166) of the trigger bar (162) through a capillary absorption action. Particularly, the ball applicators (170 and 172) will respectively roll in the directions of the arrows (F and G) for the release material (174) from the rollers (170 and 172) in the notches (164). Such action coats the sides (166) of the trigger bar (162) in a similar way to how a felt tip pen can apply and release ink onto paper, for example. The notches (164) of the retaining material (174) deposit the material (174) through another capillary absorbing action at a top and bottom of a cut line, such as the cut line (160) shown in FIG. 16, when the trigger bar (162) severs the tissue (90) in a manner described above for the end actuator (12). The firing bar (162) at the end thereby applies material (174) to the cut line (160) while simultaneously severing the fabric (90) to create the cut line (160). 2. Ampoule version [0049] As another merely illustrative example, the cartridge (119) may include a second version of the auxiliary applicator (176), which is shown in FIG. 14. The applicator 176 of this example comprises an ampoule 178, which may be comprised of plastic or any other suitable material. The ampoule (178) is disposed along a proximal end of the vertical slit (121) of the cartridge (119). When the cartridge (119) is disposed in the lower jaw (16) of the end actuator (12), the upper edge (180) of the trigger bar (162) sections the ampoule (178) into the first and second portions (182 and 184 ) on opposite sides (166) of the firing bar (162). Alternatively, when the cartridge (119) is disposed in the lower jaw (16) of the end actuator (12), the leading edge (167) of the trigger bar (162) is advanced distally to section the ampoule (178) at the first and second portions (182 and 184) on opposite sides (166) of the firing bar (162). As the trigger bar (162) advances distally through the slit (121) and through the sectioned vial (178), the agent (186) flows from the vial (178) to the sides (166) of the trigger bar (162) at a trajectory shown by the arrow (H) for retention in the notches (164) of the trigger bar (162). The agent (186) is thus applied by firing the trigger bar (162) to a cut line such as the cut line (160) shown in FIG. 16, when the trigger bar (162) severs the tissue (90) in a manner described above for the end actuator (12). 3. Spring activated gel block version [0050] As yet another merely illustrative example, the cartridge (119) may include a third version of the auxiliary applicator (188), which is shown in FIG. 15. The applicator (188) of this example comprises a gel block (190) of the agent (192) with a pair of springs (193) located on opposite sides of the gel block (190) to tilt the block (190) against the sides (166) of the firing bar (162). The block (190) is disposed along a proximal end of the vertical slot (121) of the cartridge (119). When the cartridge (119) is disposed in the lower jaw (16) of the end actuator (12), the upper edge (180) of the trigger bar (162) sections the block (190) at the block portions (194 and 196) on opposite sides (166) of the firing bar (162). Alternatively, when the cartridge (119) is disposed in the lower jaw (16) of the end actuator (12), the leading edge (167) of the trigger bar (162) is advanced distally to section the block (190) at the first and second portions (194 and 196) on opposite sides (166) of the firing bar (162). As yet another alternative, the first and second portions (194 and 196) may be preformed as two separate blocks (190) so that the firing bar (162) does not section the block (190). In either of these examples, as the firing bar (162) distally advances through the slit (121), the agent (192) retained in the block (190) is transferred from the block portions (194 and 196) to the sides (166) of the firing bar (162) for retention in the notches (164) of the firing bar (162). The springs (193) press against the outer sides of each of the block portions (194 and 196) to bias the inner sides of the block portions (194 and 196) against respective opposite sides (166) of the firing bar (162 ) as the trigger bar (162) distally advances through the slot (121) of the cartridge (119). The agent (192) is thus applied by firing the trigger bar (162) to a cut line such as the cut line (160) shown in FIG. 16, when the trigger bar (162) severs the tissue (90) in a manner described above for the end actuator (12). [0051] It is to be understood that any one or more of the teachings, expressions, modalities, examples etc. described herein may be combined with any one or more of the other teachings, expressions, modalities, examples, etc. which are described here. The teachings, expressions, modalities, examples, etc. described below should not be seen in isolation from one another. Various suitable ways in which the teachings of the present invention may be combined will be readily apparent to those skilled in the art in view of the teachings of the present invention. These modifications and variations are intended to be included within the scope of the appended claims. [0052] Versions of the devices described above may have application in conventional medical treatments and procedures conducted by a medical professional, as well as application in robotic-assisted medical treatments and procedures. [0053] Versions of the above may be designed to be discarded after a single use, or they may be designed to be used multiple times. Versions can, in either or both cases, be reconditioned for reuse after at least one use. Reconditioning can include any combination of steps of disassembling the device, followed by cleaning or replacing particular parts, and subsequent reassembly. In particular, some versions of the device can be disassembled, in any number of particular parts or parts of the device can be selectively replaced or removed in any combination. With cleaning and/or replacement of particular parts, some versions of the device can be reassembled for subsequent use in a reconditioning facility, or by a user immediately prior to a surgical procedure. Those skilled in the art will understand that reconditioning a device can utilize a variety of techniques for disassembly, cleaning/replacement and reassembly. The use of such techniques and the resulting refurbished device are all within the scope of this order. [0054] Just as an example, the versions described here can be sterilized before and/or after a procedure. In a sterilization technique, the device is placed in a closed, sealed container such as a plastic or TYVEK bag. The container and device can then be placed in a radiation field, such as gamma radiation, X-rays or high energy electrons, which can penetrate the container. Radiation can kill bacteria in the device and container. The sterilized device can then be stored in a sterile container for later use. The device may also be sterilized using any other known technique, including, but not limited to, beta or gamma radiation, ethylene oxide, or water vapor. [0055] In view of the presentation and description of various versions in this description, further adaptations of the methods and systems described in this document can be made through suitable modifications made by an expert in the art, without departing from the scope of the present invention. Several of these possible modifications have been mentioned, and others will be evident to those skilled in the art. For example, the examples, versions, geometry, materials, dimensions, proportions, steps and the like discussed above are illustrative only and are not required. Accordingly, the scope of the present invention is to be considered in accordance with the terms of the following claims and it is understood that it is not limited to the details of structure and operation shown and described in the specification and drawings.
权利要求:
Claims (14) [0001] 1. A surgical instrument apparatus (10), comprising: (a) a handle portion (20); (b) a rod (23) housing a firing bar (103, 126, 162); (c) an end actuator (12) comprising an anvil (18), a lower jaw (16), and a clamping and separating assembly responsive to a longitudinal closing movement produced by the handle portion (20) and the rod (23); and (d) a removable cartridge (101, 107, 113, 119), wherein the lower jaw (16) is configured to receive the cartridge (101, 107, 113, 119), characterized in that the cartridge comprises: (i) a housing, (j)) a plurality of clamps (47) arranged in the housing, (k) i) a holder (105, 109, 115) arranged on the plurality of clamps (47), the holder (105, 109) 115) defining openings (51), each opening being disposed in each clamp (47); and (l)) a biocompatible material (114, 138, 174, 186, 192), in which the trigger bar (103, 126, 162) is intended to apply the biocompatible material (114, 138, 174, 186, 192 ) to the fabric while the staple and separation assembly simultaneously separates and actuates the clips (47) in the fabric and wherein the trigger bar (103, 126, 162) includes a notch (110, 136, 164) configured to receive the biocompatible material (114,138, 174,186, 192). [0002] 2. Apparatus according to claim 1, characterized in that the biocompatible material (114,138, 174,186, 192) is disposed on or below the support (105, 109, 115) of the cartridge (101, 107, 113, 119 ) at a proximal end of the cartridge (101, 107, 113, 119). [0003] 3. Apparatus according to claim 1, characterized in that the biocompatible material (114,138) is wound around a pair of coils (116, 118, 140, 142). [0004] 4. Apparatus according to claim 3, characterized in that the coils (116, 118, 140, 142) are resiliently pulled. [0005] 5. Apparatus according to claim 3 or claim 4, characterized in that the biocompatible material (114,138) around the coils (116, 118, 140, 142) is configured to advance when the firing bar (103, 126) advances through the slot (99, 111, 117) of the holder (105, 109, 115) of the cartridge (101, 107, 113) in response to the longitudinal closing movement produced by the handle portion (20) and the rod ( 23). [0006] 6. Apparatus according to claim 5, characterized in that it further comprises a pair of knives (120, 122, 144, 146, 154, 156) positioned at a distal end of the slit (99, 111, 117) of the cartridge holder (105, 109, 115) (101, 107, 113). [0007] 7. Apparatus according to claim 6, characterized in that the knives (120, 122, 144, 146, 154, 156) are configured to separate the biocompatible material (114,138) when the biocompatible material (114,138) reaches the distal end (124, 148, 158) of the slit (99, 111, 117). [0008] 8. Apparatus according to any one of the preceding claims, characterized in that when the biocompatible material (114,138) comprises a tape, a notch (110, 136) in the firing bar (103, 126) is configured to receive the tape. [0009] 9. Apparatus according to any one of the preceding claims, characterized in that the area proximal to a front edge of the trigger bar (162) is configured to receive the biocompatible material (114,138, 174,186, 192). [0010] 10. Apparatus according to claim 9, characterized in that it further comprises a pair of cylinders (170, 172) configured to release the biocompatible material (174) in notches (164) on the side surfaces (166) of the bar. trigger (162) when the trigger bar (162) advances distally. [0011] 11. Apparatus according to claim 9, characterized in that it further comprises an ampoule (178) housing the biocompatible material (186), wherein the leading edge of the trigger bar (162) is configured to separate the ampoule ( 178) when the trigger bar (162) is advanced distally to release the biocompatible material (186) into notches (164) in the side surfaces (166) of the trigger bar (162). [0012] 12. Apparatus according to claim 9, characterized in that the biocompatible material (192) comprises a spring-activated gel block (190), wherein the leading edge of the trigger bar (162) is configured to advance distally beyond the gel block (190) when the trigger bar (162) is advanced distally to release the biocompatible material (192) into notches (164) in the side surfaces (166) of the trigger bar (162). [0013] 13. Apparatus according to claim 12, characterized in that the spring-activated gel block (190) comprises a pair of blocks (194, 196) resiliently tensioned against opposite sides (166) of the firing bar ( 162). [0014] 14. Apparatus according to claim 12 or claim 13, characterized in that the spring-activated gel block (190) comprises a separable block, and wherein the leading edge of the trigger bar (162) is configured to advancing distally to separate the separable block into a pair of block portions so that material (192) is released from the separate areas of the pair of block portions into notches (164) on the side surfaces (166) of the trigger bar (162 ).
类似技术:
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同族专利:
公开号 | 公开日 CN103957818B|2016-11-23| EP2757959A1|2014-07-30| US8985429B2|2015-03-24| RU2619378C2|2017-05-15| WO2013043694A1|2013-03-28| RU2014116258A|2015-10-27| US20130075451A1|2013-03-28| JP6271429B2|2018-01-31| PL2757959T3|2016-04-29| JP2014533125A|2014-12-11| CN103957818A|2014-07-30| MX2014003516A|2015-02-05| MX349051B|2017-07-06| EP2757959B1|2015-10-21|
引用文献:
公开号 | 申请日 | 公开日 | 申请人 | 专利标题 CA481943A|1952-03-25|C. Harvey Douglass|Camera controlling mechanism| GB222954A|1923-07-10|1924-10-10|Mabel Elizabeth Tilburn|Improved means for producing and for the illuminated projection-display of writings, cartoons, drawings and the like| GB493459A|1937-04-08|1938-10-10|Piero Mariano Salerni|Improvements in or relating to hydraulic power transmission apparatus| US2303131A|1941-04-25|1942-11-24|Eva M Morgan|Suturable surgical adhesive material and method of using same| GB913218A|1960-02-02|1962-12-19|Alexey Alexeevich Strekopitov|A suturing device| US3364200A|1960-03-28|1968-01-16|Johnson & Johnson|Oxidized cellulose product and method for preparing the same| US3496940A|1966-09-19|1970-02-24|Charles Steinman|Surgical suture and sling device| US3526228A|1969-03-24|1970-09-01|Ethicon Inc|Collagen lamina dural prosthesis| US4222383A|1978-08-07|1980-09-16|Schossow George W|Surgical drape and suture| US4513746A|1981-10-09|1985-04-30|United States Surgical Corp.|Instrument for applying plastic-like surgical fastening devices| SU1170663A1|1983-04-14|1987-04-23|Всесоюзный научно-исследовательский и испытательный институт медицинской техники|Compound for joning tissues and organs| US4549545A|1984-03-05|1985-10-29|Ethicon Inc.|Segmented polyurethane surgical buttressing pledgets| US4693720A|1985-09-23|1987-09-15|Katecho, Incorporated|Device for surgically repairing soft tissues and method for making the same| US4610250A|1985-10-08|1986-09-09|United States Surgical Corporation|Two-part surgical fastener for fascia wound approximation| JPS6425870A|1987-04-30|1989-01-27|Ajinomoto Kk|Support for anastomosis or bonding of living body| EP0328401A1|1988-02-11|1989-08-16|Unisearch Limited|Anastomosis augmentation device| US4805823A|1988-03-18|1989-02-21|Ethicon, Inc.|Pocket configuration for internal organ staplers| JPH06506366A|1990-12-06|1994-07-21| US5366480A|1990-12-24|1994-11-22|American Cyanamid Company|Synthetic elastomeric buttressing pledget| US5690675A|1991-02-13|1997-11-25|Fusion Medical Technologies, Inc.|Methods for sealing of staples and other fasteners in tissue| US5282829A|1991-08-15|1994-02-01|United States Surgical Corporation|Hollow body implants| US5411193A|1991-08-26|1995-05-02|Culp; Joel B.|Portable containment device for contaminated medical objects| AU3242693A|1991-12-06|1993-06-28|Kensey Nash Corporation|Pads, methods of making, and methods of use for wound dressing, surgical reinforcement and hemostasis promotion| US5496603A|1992-02-03|1996-03-05|Minnesota Mining And Manufacturing Company|Nonwoven sheet materials, tapes and methods| US5749968A|1993-03-01|1998-05-12|Focal, Inc.|Device for priming for improved adherence of gels to substrates| GB9206509D0|1992-03-25|1992-05-06|Jevco Ltd|Heteromorphic sponges containing active agents| US5263629A|1992-06-29|1993-11-23|Ethicon, Inc.|Method and apparatus for achieving hemostasis along a staple line| US5327914A|1992-09-02|1994-07-12|Shlain Leonard M|Method and devices for use in surgical gastroplastic procedure| US5383904A|1992-10-13|1995-01-24|United States Surgical Corporation|Stiffened surgical device| US6174333B1|1994-06-06|2001-01-16|Osiris Therapeutics, Inc.|Biomatrix for soft tissue regeneration using mesenchymal stem cells| US5565210A|1993-03-22|1996-10-15|Johnson & Johnson Medical, Inc.|Bioabsorbable wound implant materials| US5415334A|1993-05-05|1995-05-16|Ethicon Endo-Surgery|Surgical stapler and staple cartridge| US6704210B1|1994-05-20|2004-03-09|Medtronic, Inc.|Bioprothesis film strip for surgical stapler and method of attaching the same| US5297324A|1993-07-15|1994-03-29|Su Wen Chian|Fully rounded jingle bell making method| JP3146773B2|1993-07-26|2001-03-19|スズキ株式会社|Scooter-type motorcycle carburetor fuel oil level holding device| US5607590A|1993-08-06|1997-03-04|Shimizu; Yasuhiko|Material for medical use and process for preparing same| US5542594A|1993-10-06|1996-08-06|United States Surgical Corporation|Surgical stapling apparatus with biocompatible surgical fabric| US5393594A|1993-10-06|1995-02-28|United States Surgical Corporation|Absorbable non-woven fabric| US5597107A|1994-02-03|1997-01-28|Ethicon Endo-Surgery, Inc.|Surgical stapler instrument| US5465895A|1994-02-03|1995-11-14|Ethicon Endo-Surgery, Inc.|Surgical stapler instrument| US5503638A|1994-02-10|1996-04-02|Bio-Vascular, Inc.|Soft tissue stapling buttress| US5814057A|1994-06-03|1998-09-29|Gunze Limited|Supporting element for staple region| EP0773971B1|1994-07-27|1999-06-23|W.L. Gore & Associates, Inc.|High strength porous ptfe sheet material| US5607686A|1994-11-22|1997-03-04|United States Surgical Corporation|Polymeric composition| US5704534A|1994-12-19|1998-01-06|Ethicon Endo-Surgery, Inc.|Articulation assembly for surgical instruments| US5632432A|1994-12-19|1997-05-27|Ethicon Endo-Surgery, Inc.|Surgical instrument| CA2167455A1|1995-01-19|1996-07-20|Kevin Cooper|Absorbable polyalkylene diglycolates| KR100333508B1|1995-03-31|2002-07-18|타다시 마츠다|Process for preparing solvent-type acrylic pressure-sensitive adhesives and medical pressure-sensitive adhesive| WO1996032893A1|1995-04-21|1996-10-24|W.L. Gore & Associates, Inc.|A surgical pledget dispensing system| JP3795100B2|1995-05-08|2006-07-12|株式会社伊垣医療設計|Medical suture material| JP3526487B2|1995-05-08|2004-05-17|株式会社伊垣医療設計|Medical sutures| WO1997001989A1|1995-07-03|1997-01-23|Frater Dirk A|System for mounting bolster material on tissue staplers| JPH11509126A|1995-07-17|1999-08-17|エドワード ウッド，アルフレッド|Heart valve reconstruction buttress| US5810855A|1995-07-21|1998-09-22|Gore Enterprise Holdings, Inc.|Endoscopic device and method for reinforcing surgical staples| US5814055A|1995-09-19|1998-09-29|Ethicon Endo-Surgery, Inc.|Surgical clamping mechanism| US5639851A|1995-10-02|1997-06-17|Ethicon, Inc.|High strength, melt processable, lactide-rich, poly copolymers| JP3476631B2|1995-12-21|2003-12-10|株式会社アムニオテック|Medical material composed of human-derived natural collagen membrane| US5711958A|1996-07-11|1998-01-27|Life Medical Sciences, Inc.|Methods for reducing or eliminating post-surgical adhesion formation| US5755778A|1996-10-16|1998-05-26|Nitinol Medical Technologies, Inc.|Anastomosis device| US5752965A|1996-10-21|1998-05-19|Bio-Vascular, Inc.|Apparatus and method for producing a reinforced surgical fastener suture line| US5769892A|1996-10-22|1998-06-23|Mitroflow International Inc.|Surgical stapler sleeve for reinforcing staple lines| TW501934B|1996-11-20|2002-09-11|Tapic Int Co Ltd|Collagen material and process for making the same| JP2001514539A|1997-03-04|2001-09-11|メドトロニック・インコーポレーテッド|Bioprosthesis film strip for surgical stapler and method of attaching the same| US6475230B1|1997-08-01|2002-11-05|Peter M. Bonutti|Method and apparatus for securing a suture| US5997895A|1997-09-16|1999-12-07|Integra Lifesciences Corporation|Dural/meningeal repair product using collagen matrix| GB2329840C|1997-10-03|2007-10-05|Johnson & Johnson Medical|Biopolymer sponge tubes| WO1999034750A1|1998-01-06|1999-07-15|Bioamide, Inc.|Bioabsorbable fibers and reinforced composites produced therefrom| US6245081B1|1998-01-09|2001-06-12|Steven M. Bowman|Suture buttress| US6203564B1|1998-02-26|2001-03-20|United States Surgical|Braided polyester suture and implantable medical device| CN1105795C|1998-06-11|2003-04-16|清水庆彦|Collagen material and process for producing the same| US6099551A|1998-03-12|2000-08-08|Shelhigh, Inc.|Pericardial strip and stapler assembly for dividing and sealing visceral tissues and method of use thereof| FR2778081B1|1998-04-29|2000-08-25|Fabrice Thevenet|REINFORCEMENT IMPLANTS FOR TISSUE SUTURES| JPH11309151A|1998-04-30|1999-11-09|Nippon Waisuredarii Kk|Surgical suturing device| FR2789885B1|1999-02-19|2001-05-04|Brothier Lab|SUTURE REINFORCEMENT DEVICE| PT1163019E|1999-03-25|2007-12-06|Metabolix Inc|Medical devices and applications of polyhydroxyalkanoate polymers| US6921412B1|1999-05-18|2005-07-26|Cryolife, Inc.|Self-supporting, shaped, three-dimensional biopolymeric materials and methods| US6325810B1|1999-06-30|2001-12-04|Ethicon, Inc.|Foam buttress for stapling apparatus| US6355699B1|1999-06-30|2002-03-12|Ethicon, Inc.|Process for manufacturing biomedical foams| RU2161450C1|1999-07-22|2001-01-10|Каншин Николай Николаевич|Surgical suturing device| US6635073B2|2000-05-03|2003-10-21|Peter M. Bonutti|Method of securing body tissue| AT434010T|1999-08-27|2009-07-15|Angiodevice Internat Gmbh|INTERPENDENT POLYMER NETWORKS FOR USE AS HIGH-STRENGTH MEDICAL SEALING COMPOUNDS| EP1080693A1|1999-09-02|2001-03-07|Heinz Robert Dr. med. Zurbrügg|Haemostatic and/or reinforcing surgical suture system for sternal cerclages| US6312474B1|1999-09-15|2001-11-06|Bio-Vascular, Inc.|Resorbable implant materials| US6641592B1|1999-11-19|2003-11-04|Lsi Solutions, Inc.|System for wound closure| US6488197B1|2000-02-22|2002-12-03|Power Medical Interventions, Inc.|Fluid delivery device for use with anastomosing resecting and stapling instruments| US6273897B1|2000-02-29|2001-08-14|Ethicon, Inc.|Surgical bettress and surgical stapling apparatus| WO2002009593A1|2000-07-28|2002-02-07|Les Laboratoires Brothier|Suture reinforcing device| US20040093024A1|2000-09-01|2004-05-13|James Lousararian|Advanced wound site management systems and methods| WO2002022184A2|2000-09-18|2002-03-21|Organogenesis Inc.|Bioengineered flat sheet graft prosthesis and its use| US6638285B2|2001-04-16|2003-10-28|Shlomo Gabbay|Biological tissue strip and system and method to seal tissue| US6656193B2|2001-05-07|2003-12-02|Ethicon Endo-Surgery, Inc.|Device for attachment of buttress material to a surgical fastening device| US6503257B2|2001-05-07|2003-01-07|Ethicon Endo-Surgery, Inc.|Method for releasing buttress material attached to a surgical fastening device| US7182771B1|2001-12-20|2007-02-27|Russell A. Houser|Vascular couplers, techniques, methods, and accessories| US6939358B2|2001-12-20|2005-09-06|Gore Enterprise Holdings, Inc.|Apparatus and method for applying reinforcement material to a surgical stapler| US7128748B2|2002-03-26|2006-10-31|Synovis Life Technologies, Inc.|Circular stapler buttress combination| WO2003088844A1|2002-04-15|2003-10-30|Cook Biotech Incorporated|Apparatus and method for producing a reinforced surgical staple line| EP2404555B1|2002-04-16|2017-03-15|Covidien LP|Surgical stapler and method| EP1503674B1|2002-05-10|2006-08-23|Tyco Healthcare Group Lp|Electrosurgical stapling apparatus| CA2485107C|2002-05-10|2011-07-12|Tyco Healthcare Group Lp|Surgical stapling apparatus having a wound closure material applicator assembly| EP2289429B1|2002-05-10|2015-06-17|Covidien LP|Surgical stapling apparatus having a wound closure material applicator assembly| US6986775B2|2002-06-13|2006-01-17|Guided Delivery Systems, Inc.|Devices and methods for heart valve repair| US7744627B2|2002-06-17|2010-06-29|Tyco Healthcare Group Lp|Annular support structures| JP2006509595A|2002-12-16|2006-03-23|エドリッチ・ヴァスキュラー・ディヴァイシズ，インコーポレイテッド|Multiple stapling instruments for narrow vessels| CN100369637C|2002-12-16|2008-02-20|郡是株式会社|Medical film| CN1732023A|2002-12-27|2006-02-08|血管技术国际股份公司|Compositions and methods of using collajolie| FR2850281A1|2003-01-27|2004-07-30|Brothier Lab|Production of a suture-reinforcing device comprises coating a guluronic-type calcium alginate textile material with a solution of propylene glycol alginate with a high degree of esterification| US20040167572A1|2003-02-20|2004-08-26|Roth Noah M.|Coated medical devices| US7160299B2|2003-05-01|2007-01-09|Sherwood Services Ag|Method of fusing biomaterials with radiofrequency energy| EP1624811B1|2003-05-09|2007-02-21|Tyco Healthcare Group Lp|Anastomotic staple with fluid dispensing capillary| US20070190108A1|2004-05-17|2007-08-16|Arindam Datta|High performance reticulated elastomeric matrix preparation, properties, reinforcement, and use in surgical devices, tissue augmentation and/or tissue repair| US6988649B2|2003-05-20|2006-01-24|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument having a spent cartridge lockout| US7380696B2|2003-05-20|2008-06-03|Ethicon Endo-Surgery, Inc.|Articulating surgical stapling instrument incorporating a two-piece E-beam firing mechanism| US7380695B2|2003-05-20|2008-06-03|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument having a single lockout mechanism for prevention of firing| US7143923B2|2003-05-20|2006-12-05|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument having a firing lockout for an unclosed anvil| US6978921B2|2003-05-20|2005-12-27|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument incorporating an E-beam firing mechanism| US7905902B2|2003-06-16|2011-03-15|Ethicon Endo-Surgery, Inc.|Surgical implant with preferential corrosion zone| US6964363B2|2003-07-09|2005-11-15|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument having articulation joint support plates for supporting a firing bar| US7111769B2|2003-07-09|2006-09-26|Ethicon Endo-Surgery, Inc.|Surgical instrument incorporating an articulation mechanism having rotation about the longitudinal axis| PT1647286E|2003-07-17|2010-11-30|Gunze Kk|Stitching reinforcement material for automatic stitching device| US8198261B2|2003-08-22|2012-06-12|Xylos Corporation|Thermally modified microbial-derived cellulose for in vivo implantation| US7547312B2|2003-09-17|2009-06-16|Gore Enterprise Holdings, Inc.|Circular stapler buttress| US7434715B2|2003-09-29|2008-10-14|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument having multistroke firing with opening lockout| US7303108B2|2003-09-29|2007-12-04|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument incorporating a multi-stroke firing mechanism with a flexible rack| US20050070929A1|2003-09-30|2005-03-31|Dalessandro David A.|Apparatus and method for attaching a surgical buttress to a stapling apparatus| US20050247320A1|2003-10-10|2005-11-10|Stack Richard S|Devices and methods for retaining a gastro-esophageal implant| US20050101834A1|2003-11-10|2005-05-12|Merade Bryon L.|Readily implantable sling| US7211093B2|2004-01-14|2007-05-01|Lsi Solutions, Inc.|Sew-right running stitch instrument| US20050283256A1|2004-02-09|2005-12-22|Codman & Shurtleff, Inc.|Collagen device and method of preparing the same| GB2429651C|2004-02-17|2009-03-25|Cook Biotech Inc|Medical devices and methods useful for applying bolster material| JP4700384B2|2004-04-07|2011-06-15|オリンパス株式会社|Medical ligature suturing apparatus and medical ligature suturing system| US20050249772A1|2004-05-04|2005-11-10|Prasanna Malaviya|Hybrid biologic-synthetic bioabsorbable scaffolds| US7931578B2|2004-06-18|2011-04-26|Ncontact Surgical, Inc.|Methods and system for tissue cavity closure| US7727271B2|2004-06-24|2010-06-01|Boston Scientific Scimed, Inc.|Implantable prosthesis having reinforced attachment sites| US7367485B2|2004-06-30|2008-05-06|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument incorporating a multistroke firing mechanism having a rotary transmission| US8215531B2|2004-07-28|2012-07-10|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument having a medical substance dispenser| US7147138B2|2004-07-28|2006-12-12|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument having an electroactive polymer actuated buttress deployment mechanism| US7784663B2|2005-03-17|2010-08-31|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument having load sensing control circuitry| EP1791473A4|2004-08-17|2011-09-14|Tyco Healthcare|Stapling support structures| ES2264862B8|2004-08-25|2017-01-20|Cellerix, S.L.|BIOMATERIAL FOR SUTURE.| ES2389208T3|2004-10-18|2012-10-24|Tyco Healthcare Group Lp|Annular adhesive structure| US7845536B2|2004-10-18|2010-12-07|Tyco Healthcare Group Lp|Annular adhesive structure| AU2005295477B2|2004-10-18|2011-11-24|Covidien Lp|Structure for applying sprayable wound treatment material| DK1809342T3|2004-10-20|2015-08-17|Ethicon Inc|absorbable hemostat| WO2006081174A2|2005-01-24|2006-08-03|Brian Kelleher|Methods and devices for soft tissue stapling| US20060173470A1|2005-01-31|2006-08-03|Oray B N|Surgical fastener buttress material| US7559450B2|2005-02-18|2009-07-14|Ethicon Endo-Surgery, Inc.|Surgical instrument incorporating a fluid transfer controlled articulation mechanism| FR2884134B1|2005-04-07|2008-03-28|Safradim Production Soc Par Ac|SYSTEM FOR ESTABLISHING MEANS FORMING REINFORCEMENT OF A SUTURE| US7250057B2|2005-04-11|2007-07-31|St. Jude Medical Puerto Rico B.V.|Tissue puncture closure device with automatic torque sensing tamping system| US7837705B2|2005-05-17|2010-11-23|St. Jude Medical Puerto Rico Llc|Tissue puncture closure system with retractable sheath| US7618438B2|2005-05-17|2009-11-17|St. Jude Medical Puerto Rico Llc|Tissue puncture closure device with disengagable automatic tamping system| US7500993B2|2005-07-15|2009-03-10|Towertech Research Group, Inc.|Ventral hernia repair method| US8579176B2|2005-07-26|2013-11-12|Ethicon Endo-Surgery, Inc.|Surgical stapling and cutting device and method for using the device| US7559937B2|2005-08-09|2009-07-14|Towertech Research Group|Surgical fastener apparatus and reinforcing material| US7401721B2|2005-08-15|2008-07-22|Tyco Healthcare Group Lp|Surgical stapling instruments including a cartridge having multiple staple sizes| US7398908B2|2005-08-15|2008-07-15|Tyco Healthcare Group Lp|Surgical stapling instruments including a cartridge having multiple staple sizes| US9055942B2|2005-10-03|2015-06-16|Boston Scienctific Scimed, Inc.|Endoscopic plication devices and methods| US7673783B2|2005-11-04|2010-03-09|Ethicon Endo-Surgery, Inc.|Surgical stapling instruments structured for delivery of medical agents| US7607557B2|2005-11-04|2009-10-27|Ethicon Endo-Surgery, Inc.|Surgical stapling instruments structured for pump-assisted delivery of medical agents| US20070112360A1|2005-11-15|2007-05-17|Patrick De Deyne|Bioprosthetic device| US20070128243A1|2005-12-02|2007-06-07|Xylos Corporation|Implantable microbial cellulose materials for various medical applications| WO2007067621A2|2005-12-06|2007-06-14|Tyco Healthcare Group Lp|Biocompatible surgical compositions| US8267942B2|2005-12-23|2012-09-18|Ethicon, Inc.|Systems and methods for closing a vessel wound| US20070207180A1|2006-03-02|2007-09-06|Masao Tanihara|Synthetic polypeptide-containing bioapplicable material and film-forming material| US7709631B2|2006-03-13|2010-05-04|Xylos Corporation|Oxidized microbial cellulose and use thereof| JP5076586B2|2006-03-30|2012-11-21|大日本印刷株式会社|Embossing device| US20080039871A1|2006-04-04|2008-02-14|Wallace Jeffrey M|Minimally invasive gastric restriction methods| US20070243227A1|2006-04-14|2007-10-18|Michael Gertner|Coatings for surgical staplers| US20070246505A1|2006-04-24|2007-10-25|Medical Ventures Inc.|Surgical buttress assemblies and methods of uses thereof| US20070286892A1|2006-06-13|2007-12-13|Uri Herzberg|Compositions and methods for preventing or reducing postoperative ileus and gastric stasis in mammals| US7780663B2|2006-09-22|2010-08-24|Ethicon Endo-Surgery, Inc.|End effector coatings for electrosurgical instruments| US7557167B2|2006-09-28|2009-07-07|Gore Enterprise Holdings, Inc.|Polyester compositions, methods of manufacturing said compositions, and articles made therefrom| US8360297B2|2006-09-29|2013-01-29|Ethicon Endo-Surgery, Inc.|Surgical cutting and stapling instrument with self adjusting anvil| US8028883B2|2006-10-26|2011-10-04|Tyco Healthcare Group Lp|Methods of using shape memory alloys for buttress attachment| US7708180B2|2006-11-09|2010-05-04|Ethicon Endo-Surgery, Inc.|Surgical fastening device with initiator impregnation of a matrix or buttress to improve adhesive application| US8834498B2|2006-11-10|2014-09-16|Ethicon Endo-Surgery, Inc.|Method and device for effecting anastomosis of hollow organ structures using adhesive and fasteners| US7753936B2|2006-11-10|2010-07-13|Ehticon Endo-Surgery, Inc.|Form in place fasteners| US7721930B2|2006-11-10|2010-05-25|Thicon Endo-Surgery, Inc.|Disposable cartridge with adhesive for use with a stapling device| US7738971B2|2007-01-10|2010-06-15|Ethicon Endo-Surgery, Inc.|Post-sterilization programming of surgical instruments| US8540128B2|2007-01-11|2013-09-24|Ethicon Endo-Surgery, Inc.|Surgical stapling device with a curved end effector| US8011555B2|2007-03-06|2011-09-06|Tyco Healthcare Group Lp|Surgical stapling apparatus| US8038045B2|2007-05-25|2011-10-18|Tyco Healthcare Group Lp|Staple buttress retention system| US7665646B2|2007-06-18|2010-02-23|Tyco Healthcare Group Lp|Interlocking buttress material retention system| US7950561B2|2007-06-18|2011-05-31|Tyco Healthcare Group Lp|Structure for attachment of buttress material to anvils and cartridges of surgical staplers| US7845533B2|2007-06-22|2010-12-07|Tyco Healthcare Group Lp|Detachable buttress material retention systems for use with a surgical stapling device| US8062330B2|2007-06-27|2011-11-22|Tyco Healthcare Group Lp|Buttress and surgical stapling apparatus| US8070036B1|2007-09-06|2011-12-06|Cardica, Inc|True multi-fire surgical stapler configured to fire staples of different sizes| US8317790B2|2007-09-14|2012-11-27|W. L. Gore & Associates, Inc.|Surgical staple line reinforcements| US8678263B2|2007-09-24|2014-03-25|Covidien Lp|Materials delivery system for stapling device| US20090118747A1|2007-11-05|2009-05-07|Tyco Healthcare Group Lp|Novel surgical fastener| US8016178B2|2009-03-31|2011-09-13|Tyco Healthcare Group Lp|Surgical stapling apparatus| US8157151B2|2009-10-15|2012-04-17|Tyco Healthcare Group Lp|Staple line reinforcement for anvil and cartridge| US8186558B2|2009-11-10|2012-05-29|Tyco Healthcare Group Lp|Locking mechanism for use with loading units| US8740037B2|2010-09-30|2014-06-03|Ethicon Endo-Surgery, Inc.|Compressible fastener cartridge|US5865361A|1997-09-23|1999-02-02|United States Surgical Corporation|Surgical stapling apparatus| US9060770B2|2003-05-20|2015-06-23|Ethicon Endo-Surgery, Inc.|Robotically-driven surgical instrument with E-beam driver| US20070084897A1|2003-05-20|2007-04-19|Shelton Frederick E Iv|Articulating surgical stapling instrument incorporating a two-piece e-beam firing mechanism| US8215531B2|2004-07-28|2012-07-10|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument having a medical substance dispenser| US10159482B2|2005-08-31|2018-12-25|Ethicon Llc|Fastener cartridge assembly comprising a fixed anvil and different staple heights| US7669746B2|2005-08-31|2010-03-02|Ethicon Endo-Surgery, Inc.|Staple cartridges for forming staples having differing formed staple heights| US11246590B2|2005-08-31|2022-02-15|Cilag Gmbh International|Staple cartridge including staple drivers having different unfired heights| US9237891B2|2005-08-31|2016-01-19|Ethicon Endo-Surgery, Inc.|Robotically-controlled surgical stapling devices that produce formed staples having different lengths| US20070106317A1|2005-11-09|2007-05-10|Shelton Frederick E Iv|Hydraulically and electrically actuated articulation joints for surgical instruments| US7753904B2|2006-01-31|2010-07-13|Ethicon Endo-Surgery, Inc.|Endoscopic surgical instrument with a handle that can articulate with respect to the shaft| US11207064B2|2011-05-27|2021-12-28|Cilag Gmbh International|Automated end effector component reloading system for use with a robotic system| US7845537B2|2006-01-31|2010-12-07|Ethicon Endo-Surgery, Inc.|Surgical instrument having recording capabilities| US8820603B2|2006-01-31|2014-09-02|Ethicon Endo-Surgery, Inc.|Accessing data stored in a memory of a surgical instrument| US20120292367A1|2006-01-31|2012-11-22|Ethicon Endo-Surgery, Inc.|Robotically-controlled end effector| US8186555B2|2006-01-31|2012-05-29|Ethicon Endo-Surgery, Inc.|Motor-driven surgical cutting and fastening instrument with mechanical closure system| US11224427B2|2006-01-31|2022-01-18|Cilag Gmbh International|Surgical stapling system including a console and retraction assembly| US20110295295A1|2006-01-31|2011-12-01|Ethicon Endo-Surgery, Inc.|Robotically-controlled surgical instrument having recording capabilities| US8608043B2|2006-10-06|2013-12-17|Covidien Lp|Surgical instrument having a multi-layered drive beam| US8652120B2|2007-01-10|2014-02-18|Ethicon Endo-Surgery, Inc.|Surgical instrument with wireless communication between control unit and sensor transponders| US8684253B2|2007-01-10|2014-04-01|Ethicon Endo-Surgery, Inc.|Surgical instrument with wireless communication between a control unit of a robotic system and remote sensor| US11039836B2|2007-01-11|2021-06-22|Cilag Gmbh International|Staple cartridge for use with a surgical stapling instrument| US7735703B2|2007-03-15|2010-06-15|Ethicon Endo-Surgery, Inc.|Re-loadable surgical stapling instrument| US8931682B2|2007-06-04|2015-01-13|Ethicon Endo-Surgery, Inc.|Robotically-controlled shaft based rotary drive systems for surgical instruments| US7753245B2|2007-06-22|2010-07-13|Ethicon Endo-Surgery, Inc.|Surgical stapling instruments| US8061576B2|2007-08-31|2011-11-22|Tyco Healthcare Group Lp|Surgical instrument| US9179912B2|2008-02-14|2015-11-10|Ethicon Endo-Surgery, Inc.|Robotically-controlled motorized surgical cutting and fastening instrument| US8758391B2|2008-02-14|2014-06-24|Ethicon Endo-Surgery, Inc.|Interchangeable tools for surgical instruments| US8573465B2|2008-02-14|2013-11-05|Ethicon Endo-Surgery, Inc.|Robotically-controlled surgical end effector system with rotary actuated closure systems| JP5410110B2|2008-02-14|2014-02-05|エシコン・エンド−サージェリィ・インコーポレイテッド|Surgical cutting / fixing instrument with RF electrode| US7819298B2|2008-02-14|2010-10-26|Ethicon Endo-Surgery, Inc.|Surgical stapling apparatus with control features operable with one hand| US7866527B2|2008-02-14|2011-01-11|Ethicon Endo-Surgery, Inc.|Surgical stapling apparatus with interlockable firing system| US8636736B2|2008-02-14|2014-01-28|Ethicon Endo-Surgery, Inc.|Motorized surgical cutting and fastening instrument| US9585657B2|2008-02-15|2017-03-07|Ethicon Endo-Surgery, Llc|Actuator for releasing a layer of material from a surgical end effector| US8628544B2|2008-09-23|2014-01-14|Covidien Lp|Knife bar for surgical instrument| US9386983B2|2008-09-23|2016-07-12|Ethicon Endo-Surgery, Llc|Robotically-controlled motorized surgical instrument| US7988028B2|2008-09-23|2011-08-02|Tyco Healthcare Group Lp|Surgical instrument having an asymmetric dynamic clamping member| US8210411B2|2008-09-23|2012-07-03|Ethicon Endo-Surgery, Inc.|Motor-driven surgical cutting instrument| US8608045B2|2008-10-10|2013-12-17|Ethicon Endo-Sugery, Inc.|Powered surgical cutting and stapling apparatus with manually retractable firing system| US8517239B2|2009-02-05|2013-08-27|Ethicon Endo-Surgery, Inc.|Surgical stapling instrument comprising a magnetic element driver| US20110024477A1|2009-02-06|2011-02-03|Hall Steven G|Driven Surgical Stapler Improvements| US8220688B2|2009-12-24|2012-07-17|Ethicon Endo-Surgery, Inc.|Motor-driven surgical cutting instrument with electric actuator directional control assembly| US8777004B2|2010-09-30|2014-07-15|Ethicon Endo-Surgery, Inc.|Compressible staple cartridge comprising alignment members| US9861361B2|2010-09-30|2018-01-09|Ethicon Llc|Releasable tissue thickness compensator and fastener cartridge having the same| US9232941B2|2010-09-30|2016-01-12|Ethicon Endo-Surgery, Inc.|Tissue thickness compensator comprising a reservoir| JP6305979B2|2012-03-28|2018-04-04|エシコン・エンド−サージェリィ・インコーポレイテッドＥｔｈｉｃｏｎ Ｅｎｄｏ−Ｓｕｒｇｅｒｙ，Ｉｎｃ．|Tissue thickness compensator with multiple layers| US9204880B2|2012-03-28|2015-12-08|Ethicon Endo-Surgery, Inc.|Tissue thickness compensator comprising capsules defining a low pressure environment| US10945731B2|2010-09-30|2021-03-16|Ethicon Llc|Tissue thickness compensator comprising controlled release and expansion| US9314246B2|2010-09-30|2016-04-19|Ethicon Endo-Surgery, Llc|Tissue stapler having a thickness compensator incorporating an anti-inflammatory agent| JP6224070B2|2012-03-28|2017-11-01|エシコン・エンド−サージェリィ・インコーポレイテッドＥｔｈｉｃｏｎ Ｅｎｄｏ−Ｓｕｒｇｅｒｙ，Ｉｎｃ．|Retainer assembly including tissue thickness compensator| US9629814B2|2010-09-30|2017-04-25|Ethicon Endo-Surgery, Llc|Tissue thickness compensator configured to redistribute compressive forces| BR112013027794B1|2011-04-29|2020-12-15|Ethicon Endo-Surgery, Inc|CLAMP CARTRIDGE SET| US8695866B2|2010-10-01|2014-04-15|Ethicon Endo-Surgery, Inc.|Surgical instrument having a power control circuit| US9198662B2|2012-03-28|2015-12-01|Ethicon Endo-Surgery, Inc.|Tissue thickness compensator having improved visibility| US9072535B2|2011-05-27|2015-07-07|Ethicon Endo-Surgery, Inc.|Surgical stapling instruments with rotatable staple deployment arrangements| US9089326B2|2011-10-07|2015-07-28|Ethicon Endo-Surgery, Inc.|Dual staple cartridge for surgical stapler| US8740036B2|2011-12-01|2014-06-03|Covidien Lp|Surgical instrument with actuator spring arm| US9044230B2|2012-02-13|2015-06-02|Ethicon Endo-Surgery, Inc.|Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status| US9307989B2|2012-03-28|2016-04-12|Ethicon Endo-Surgery, Llc|Tissue stapler having a thickness compensator incorportating a hydrophobic agent| MX350846B|2012-03-28|2017-09-22|Ethicon Endo Surgery Inc|Tissue thickness compensator comprising capsules defining a low pressure environment.| US9101358B2|2012-06-15|2015-08-11|Ethicon Endo-Surgery, Inc.|Articulatable surgical instrument comprising a firing drive| US20140001231A1|2012-06-28|2014-01-02|Ethicon Endo-Surgery, Inc.|Firing system lockout arrangements for surgical instruments| RU2636861C2|2012-06-28|2017-11-28|Этикон Эндо-Серджери, Инк.|Blocking of empty cassette with clips| US9364230B2|2012-06-28|2016-06-14|Ethicon Endo-Surgery, Llc|Surgical stapling instruments with rotary joint assemblies| US11197671B2|2012-06-28|2021-12-14|Cilag Gmbh International|Stapling assembly comprising a lockout| US20140005718A1|2012-06-28|2014-01-02|Ethicon Endo-Surgery, Inc.|Multi-functional powered surgical device with external dissection features| RU2669463C2|2013-03-01|2018-10-11|Этикон Эндо-Серджери, Инк.|Surgical instrument with soft stop| US9629628B2|2013-03-13|2017-04-25|Covidien Lp|Surgical stapling apparatus| US9814463B2|2013-03-13|2017-11-14|Covidien Lp|Surgical stapling apparatus| US9289211B2|2013-03-13|2016-03-22|Covidien Lp|Surgical stapling apparatus| US9717498B2|2013-03-13|2017-08-01|Covidien Lp|Surgical stapling apparatus| US9629629B2|2013-03-14|2017-04-25|Ethicon Endo-Surgey, LLC|Control systems for surgical instruments| US9687230B2|2013-03-14|2017-06-27|Ethicon Llc|Articulatable surgical instrument comprising a firing drive| US10136887B2|2013-04-16|2018-11-27|Ethicon Llc|Drive system decoupling arrangement for a surgical instrument| US20150053746A1|2013-08-23|2015-02-26|Ethicon Endo-Surgery, Inc.|Torque optimization for surgical instruments| MX369362B|2013-08-23|2019-11-06|Ethicon Endo Surgery Llc|Firing member retraction devices for powered surgical instruments.| US9662108B2|2013-08-30|2017-05-30|Covidien Lp|Surgical stapling apparatus| WO2015065485A1|2013-11-04|2015-05-07|Covidien Lp|Surgical fastener applying apparatus| CN105682567B|2013-11-04|2021-09-10|柯惠Lp公司|Surgical fastener applying apparatus| US10517593B2|2013-11-04|2019-12-31|Covidien Lp|Surgical fastener applying apparatus| US9867613B2|2013-12-19|2018-01-16|Covidien Lp|Surgical staples and end effectors for deploying the same| US9962161B2|2014-02-12|2018-05-08|Ethicon Llc|Deliverable surgical instrument| US9848874B2|2014-02-14|2017-12-26|Covidien Lp|Small diameter endoscopic stapler| US11259799B2|2014-03-26|2022-03-01|Cilag Gmbh International|Interface systems for use with surgical instruments| US10004497B2|2014-03-26|2018-06-26|Ethicon Llc|Interface systems for use with surgical instruments| US9757126B2|2014-03-31|2017-09-12|Covidien Lp|Surgical stapling apparatus with firing lockout mechanism| US10561422B2|2014-04-16|2020-02-18|Ethicon Llc|Fastener cartridge comprising deployable tissue engaging members| JP6612256B2|2014-04-16|2019-11-27|エシコンエルエルシー|Fastener cartridge with non-uniform fastener| US9668733B2|2014-04-21|2017-06-06|Covidien Lp|Stapling device with features to prevent inadvertent firing of staples| US9861366B2|2014-05-06|2018-01-09|Covidien Lp|Ejecting assembly for a surgical stapler| BR112017004361A2|2014-09-05|2017-12-05|Ethicon Llc|medical overcurrent modular power supply| US9757128B2|2014-09-05|2017-09-12|Ethicon Llc|Multiple sensors with one sensor affecting a second sensor's output or interpretation| BR112017005981A2|2014-09-26|2017-12-19|Ethicon Llc|surgical staplers and ancillary materials| US9801627B2|2014-09-26|2017-10-31|Ethicon Llc|Fastener cartridge for creating a flexible staple line| US10076325B2|2014-10-13|2018-09-18|Ethicon Llc|Surgical stapling apparatus comprising a tissue stop| US9924944B2|2014-10-16|2018-03-27|Ethicon Llc|Staple cartridge comprising an adjunct material| US11141153B2|2014-10-29|2021-10-12|Cilag Gmbh International|Staple cartridges comprising driver arrangements| US9844376B2|2014-11-06|2017-12-19|Ethicon Llc|Staple cartridge comprising a releasable adjunct material| US10736636B2|2014-12-10|2020-08-11|Ethicon Llc|Articulatable surgical instrument system| US10085748B2|2014-12-18|2018-10-02|Ethicon Llc|Locking arrangements for detachable shaft assemblies with articulatable surgical end effectors| US9987000B2|2014-12-18|2018-06-05|Ethicon Llc|Surgical instrument assembly comprising a flexible articulation system| US9968355B2|2014-12-18|2018-05-15|Ethicon Llc|Surgical instruments with articulatable end effectors and improved firing beam support arrangements| US9844375B2|2014-12-18|2017-12-19|Ethicon Llc|Drive arrangements for articulatable surgical instruments| US9844374B2|2014-12-18|2017-12-19|Ethicon Llc|Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member| CN104434250B|2014-12-30|2017-01-18|苏州天臣国际医疗科技有限公司|Reload unit and medical stapler using same| US10039545B2|2015-02-23|2018-08-07|Covidien Lp|Double fire stapling| US10285698B2|2015-02-26|2019-05-14|Covidien Lp|Surgical apparatus| US10085749B2|2015-02-26|2018-10-02|Covidien Lp|Surgical apparatus with conductor strain relief| US11154301B2|2015-02-27|2021-10-26|Cilag Gmbh International|Modular stapling assembly| US10245033B2|2015-03-06|2019-04-02|Ethicon Llc|Surgical instrument comprising a lockable battery housing| US9993248B2|2015-03-06|2018-06-12|Ethicon Endo-Surgery, Llc|Smart sensors with local signal processing| US10687806B2|2015-03-06|2020-06-23|Ethicon Llc|Adaptive tissue compression techniques to adjust closure rates for multiple tissue types| US10548504B2|2015-03-06|2020-02-04|Ethicon Llc|Overlaid multi sensor radio frequencyelectrode system to measure tissue compression| US9901342B2|2015-03-06|2018-02-27|Ethicon Endo-Surgery, Llc|Signal and power communication system positioned on a rotatable shaft| US9924961B2|2015-03-06|2018-03-27|Ethicon Endo-Surgery, Llc|Interactive feedback system for powered surgical instruments| US10617412B2|2015-03-06|2020-04-14|Ethicon Llc|System for detecting the mis-insertion of a staple cartridge into a surgical stapler| US9918717B2|2015-03-18|2018-03-20|Covidien Lp|Pivot mechanism for surgical device| US10548593B2|2015-03-25|2020-02-04|Ethicon Llc|Flowable bioabsorbable polymer adhesive for releasably attaching a staple buttress to a surgical stapler| US10463368B2|2015-04-10|2019-11-05|Covidien Lp|Endoscopic stapler| US10117650B2|2015-05-05|2018-11-06|Covidien Lp|Adapter assembly and loading units for surgical stapling devices| US10299789B2|2015-05-05|2019-05-28|Covidie LP|Adapter assembly for surgical stapling devices| US10039532B2|2015-05-06|2018-08-07|Covidien Lp|Surgical instrument with articulation assembly| US10349941B2|2015-05-27|2019-07-16|Covidien Lp|Multi-fire lead screw stapling device| US10172615B2|2015-05-27|2019-01-08|Covidien Lp|Multi-fire push rod stapling device| CN106237492A|2015-06-14|2016-12-21|上海市第人民医院|The beta-elemene bracket for controlling releasing and elution of preventing and treating Coronary Artery In-Stent Restenosis| US10548599B2|2015-07-20|2020-02-04|Covidien Lp|Endoscopic stapler and staple| US9987012B2|2015-07-21|2018-06-05|Covidien Lp|Small diameter cartridge design for a surgical stapling instrument| US10064622B2|2015-07-29|2018-09-04|Covidien Lp|Surgical stapling loading unit with stroke counter and lockout| US10045782B2|2015-07-30|2018-08-14|Covidien Lp|Surgical stapling loading unit with stroke counter and lockout| CN108024810A|2015-07-30|2018-05-11|伊西康有限责任公司|Include the surgical instruments of the optional cross-section system for allowing tissue| US11058425B2|2015-08-17|2021-07-13|Ethicon Llc|Implantable layers for a surgical instrument| US11039832B2|2015-08-24|2021-06-22|Cilag Gmbh International|Surgical stapler buttress applicator with spent staple cartridge lockout| US10166023B2|2015-08-24|2019-01-01|Ethicon Llc|Method of applying a buttress to a surgical stapler end effector| US10105139B2|2015-09-23|2018-10-23|Ethicon Llc|Surgical stapler having downstream current-based motor control| US10238386B2|2015-09-23|2019-03-26|Ethicon Llc|Surgical stapler having motor control based on an electrical parameter related to a motor current| US10299878B2|2015-09-25|2019-05-28|Ethicon Llc|Implantable adjunct systems for determining adjunct skew| US10980539B2|2015-09-30|2021-04-20|Ethicon Llc|Implantable adjunct comprising bonded layers| US10285699B2|2015-09-30|2019-05-14|Ethicon Llc|Compressible adjunct| US10561420B2|2015-09-30|2020-02-18|Ethicon Llc|Tubular absorbable constructs| US10213204B2|2015-10-02|2019-02-26|Covidien Lp|Micro surgical instrument and loading unit for use therewith| US10772632B2|2015-10-28|2020-09-15|Covidien Lp|Surgical stapling device with triple leg staples| US10595864B2|2015-11-24|2020-03-24|Covidien Lp|Adapter assembly for interconnecting electromechanical surgical devices and surgical loading units, and surgical systems thereof| US10111660B2|2015-12-03|2018-10-30|Covidien Lp|Surgical stapler flexible distal tip| US10265068B2|2015-12-30|2019-04-23|Ethicon Llc|Surgical instruments with separable motors and motor control circuits| US10368865B2|2015-12-30|2019-08-06|Ethicon Llc|Mechanisms for compensating for drivetrain failure in powered surgical instruments| US10292704B2|2015-12-30|2019-05-21|Ethicon Llc|Mechanisms for compensating for battery pack failure in powered surgical instruments| US10413291B2|2016-02-09|2019-09-17|Ethicon Llc|Surgical instrument articulation mechanism with slotted secondary constraint| US11213293B2|2016-02-09|2022-01-04|Cilag Gmbh International|Articulatable surgical instruments with single articulation link arrangements| US10349937B2|2016-02-10|2019-07-16|Covidien Lp|Surgical stapler with articulation locking mechanism| US10420559B2|2016-02-11|2019-09-24|Covidien Lp|Surgical stapler with small diameter endoscopic portion| US11224426B2|2016-02-12|2022-01-18|Cilag Gmbh International|Mechanisms for compensating for drivetrain failure in powered surgical instruments| US10617413B2|2016-04-01|2020-04-14|Ethicon Llc|Closure system arrangements for surgical cutting and stapling devices with separate and distinct firing shafts| US10357247B2|2016-04-15|2019-07-23|Ethicon Llc|Surgical instrument with multiple program responses during a firing motion| US10335145B2|2016-04-15|2019-07-02|Ethicon Llc|Modular surgical instrument with configurable operating mode| US11179150B2|2016-04-15|2021-11-23|Cilag Gmbh International|Systems and methods for controlling a surgical stapling and cutting instrument| US10456137B2|2016-04-15|2019-10-29|Ethicon Llc|Staple formation detection mechanisms| US10368867B2|2016-04-18|2019-08-06|Ethicon Llc|Surgical instrument comprising a lockout| US11065022B2|2016-05-17|2021-07-20|Covidien Lp|Cutting member for a surgical instrument| US10631857B2|2016-11-04|2020-04-28|Covidien Lp|Loading unit for surgical instruments with low profile pushers| US10675026B2|2016-12-21|2020-06-09|Ethicon Llc|Methods of stapling tissue| JP2020501779A|2016-12-21|2020-01-23|エシコン エルエルシーＥｔｈｉｃｏｎ ＬＬＣ|Surgical stapling system| US11179155B2|2016-12-21|2021-11-23|Cilag Gmbh International|Anvil arrangements for surgical staplers| US11160551B2|2016-12-21|2021-11-02|Cilag Gmbh International|Articulatable surgical stapling instruments| US20180168633A1|2016-12-21|2018-06-21|Ethicon Endo-Surgery, Llc|Surgical stapling instruments and staple-forming anvils| US20180168598A1|2016-12-21|2018-06-21|Ethicon Endo-Surgery, Llc|Staple forming pocket arrangements comprising zoned forming surface grooves| US11134942B2|2016-12-21|2021-10-05|Cilag Gmbh International|Surgical stapling instruments and staple-forming anvils| US20180168625A1|2016-12-21|2018-06-21|Ethicon Endo-Surgery, Llc|Surgical stapling instruments with smart staple cartridges| US20180168618A1|2016-12-21|2018-06-21|Ethicon Endo-Surgery, Llc|Surgical stapling systems| US11191539B2|2016-12-21|2021-12-07|Cilag Gmbh International|Shaft assembly comprising a manually-operable retraction system for use with a motorized surgical instrument system| US10779823B2|2016-12-21|2020-09-22|Ethicon Llc|Firing member pin angle| US20180168608A1|2016-12-21|2018-06-21|Ethicon Endo-Surgery, Llc|Surgical instrument system comprising an end effector lockout and a firing assembly lockout| US10736629B2|2016-12-21|2020-08-11|Ethicon Llc|Surgical tool assemblies with clutching arrangements for shifting between closure systems with closure stroke reduction features and articulation and firing systems| US10888322B2|2016-12-21|2021-01-12|Ethicon Llc|Surgical instrument comprising a cutting member| US10888321B2|2017-06-20|2021-01-12|Ethicon Llc|Systems and methods for controlling velocity of a displacement member of a surgical stapling and cutting instrument| US10307170B2|2017-06-20|2019-06-04|Ethicon Llc|Method for closed loop control of motor velocity of a surgical stapling and cutting instrument| US11071554B2|2017-06-20|2021-07-27|Cilag Gmbh International|Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on magnitude of velocity error measurements| US10980537B2|2017-06-20|2021-04-20|Ethicon Llc|Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured time over a specified number of shaft rotations| USD890784S1|2017-06-20|2020-07-21|Ethicon Llc|Display panel with changeable graphical user interface| US10624633B2|2017-06-20|2020-04-21|Ethicon Llc|Systems and methods for controlling motor velocity of a surgical stapling and cutting instrument| US11090046B2|2017-06-20|2021-08-17|Cilag Gmbh International|Systems and methods for controlling displacement member motion of a surgical stapling and cutting instrument| USD879808S1|2017-06-20|2020-03-31|Ethicon Llc|Display panel with graphical user interface| US10813639B2|2017-06-20|2020-10-27|Ethicon Llc|Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on system conditions| US10881396B2|2017-06-20|2021-01-05|Ethicon Llc|Surgical instrument with variable duration trigger arrangement| US10881399B2|2017-06-20|2021-01-05|Ethicon Llc|Techniques for adaptive control of motor velocity of a surgical stapling and cutting instrument| USD879809S1|2017-06-20|2020-03-31|Ethicon Llc|Display panel with changeable graphical user interface| US10646220B2|2017-06-20|2020-05-12|Ethicon Llc|Systems and methods for controlling displacement member velocity for a surgical instrument| US10779820B2|2017-06-20|2020-09-22|Ethicon Llc|Systems and methods for controlling motor speed according to user input for a surgical instrument| US11141154B2|2017-06-27|2021-10-12|Cilag Gmbh International|Surgical end effectors and anvils| US10856869B2|2017-06-27|2020-12-08|Ethicon Llc|Surgical anvil arrangements| US10993716B2|2017-06-27|2021-05-04|Ethicon Llc|Surgical anvil arrangements| US11266405B2|2017-06-27|2022-03-08|Cilag Gmbh International|Surgical anvil manufacturing methods| US10772629B2|2017-06-27|2020-09-15|Ethicon Llc|Surgical anvil arrangements| US10716614B2|2017-06-28|2020-07-21|Ethicon Llc|Surgical shaft assemblies with slip ring assemblies with increased contact pressure| US10903685B2|2017-06-28|2021-01-26|Ethicon Llc|Surgical shaft assemblies with slip ring assemblies forming capacitive channels| US11246592B2|2017-06-28|2022-02-15|Cilag Gmbh International|Surgical instrument comprising an articulation system lockable to a frame| US10765427B2|2017-06-28|2020-09-08|Ethicon Llc|Method for articulating a surgical instrument| US20190000474A1|2017-06-28|2019-01-03|Ethicon Llc|Surgical instrument comprising selectively actuatable rotatable couplers| US10639037B2|2017-06-28|2020-05-05|Ethicon Llc|Surgical instrument with axially movable closure member| USD906355S1|2017-06-28|2020-12-29|Ethicon Llc|Display screen or portion thereof with a graphical user interface for a surgical instrument| US11259805B2|2017-06-28|2022-03-01|Cilag Gmbh International|Surgical instrument comprising firing member supports| US10932772B2|2017-06-29|2021-03-02|Ethicon Llc|Methods for closed loop velocity control for robotic surgical instrument| US11007022B2|2017-06-29|2021-05-18|Ethicon Llc|Closed loop velocity control techniques based on sensed tissue parameters for robotic surgical instrument| US10898183B2|2017-06-29|2021-01-26|Ethicon Llc|Robotic surgical instrument with closed loop feedback techniques for advancement of closure member during firing| US10743872B2|2017-09-29|2020-08-18|Ethicon Llc|System and methods for controlling a display of a surgical instrument| USD907647S1|2017-09-29|2021-01-12|Ethicon Llc|Display screen or portion thereof with animated graphical user interface| US10729501B2|2017-09-29|2020-08-04|Ethicon Llc|Systems and methods for language selection of a surgical instrument| US10765429B2|2017-09-29|2020-09-08|Ethicon Llc|Systems and methods for providing alerts according to the operational state of a surgical instrument| USD907648S1|2017-09-29|2021-01-12|Ethicon Llc|Display screen or portion thereof with animated graphical user interface| USD917500S1|2017-09-29|2021-04-27|Ethicon Llc|Display screen or portion thereof with graphical user interface| US11090075B2|2017-10-30|2021-08-17|Cilag Gmbh International|Articulation features for surgical end effector| US11134944B2|2017-10-30|2021-10-05|Cilag Gmbh International|Surgical stapler knife motion controls| US10842490B2|2017-10-31|2020-11-24|Ethicon Llc|Cartridge body design with force reduction based on firing completion| US10779903B2|2017-10-31|2020-09-22|Ethicon Llc|Positive shaft rotation lock activated by jaw closure| US11033267B2|2017-12-15|2021-06-15|Ethicon Llc|Systems and methods of controlling a clamping member firing rate of a surgical instrument| US10828033B2|2017-12-15|2020-11-10|Ethicon Llc|Handheld electromechanical surgical instruments with improved motor control arrangements for positioning components of an adapter coupled thereto| US11197670B2|2017-12-15|2021-12-14|Cilag Gmbh International|Surgical end effectors with pivotal jaws configured to touch at their respective distal ends when fully closed| US10687813B2|2017-12-15|2020-06-23|Ethicon Llc|Adapters with firing stroke sensing arrangements for use in connection with electromechanical surgical instruments| US10743874B2|2017-12-15|2020-08-18|Ethicon Llc|Sealed adapters for use with electromechanical surgical instruments| US10779825B2|2017-12-15|2020-09-22|Ethicon Llc|Adapters with end effector position sensing and control arrangements for use in connection with electromechanical surgical instruments| US11071543B2|2017-12-15|2021-07-27|Cilag Gmbh International|Surgical end effectors with clamping assemblies configured to increase jaw aperture ranges| US10869666B2|2017-12-15|2020-12-22|Ethicon Llc|Adapters with control systems for controlling multiple motors of an electromechanical surgical instrument| US10743875B2|2017-12-15|2020-08-18|Ethicon Llc|Surgical end effectors with jaw stiffener arrangements configured to permit monitoring of firing member| US10966718B2|2017-12-15|2021-04-06|Ethicon Llc|Dynamic clamping assemblies with improved wear characteristics for use in connection with electromechanical surgical instruments| US10779826B2|2017-12-15|2020-09-22|Ethicon Llc|Methods of operating surgical end effectors| US11006955B2|2017-12-15|2021-05-18|Ethicon Llc|End effectors with positive jaw opening features for use with adapters for electromechanical surgical instruments| US10835330B2|2017-12-19|2020-11-17|Ethicon Llc|Method for determining the position of a rotatable jaw of a surgical instrument attachment assembly| US10729509B2|2017-12-19|2020-08-04|Ethicon Llc|Surgical instrument comprising closure and firing locking mechanism| USD910847S1|2017-12-19|2021-02-16|Ethicon Llc|Surgical instrument assembly| US10716565B2|2017-12-19|2020-07-21|Ethicon Llc|Surgical instruments with dual articulation drivers| US11020112B2|2017-12-19|2021-06-01|Ethicon Llc|Surgical tools configured for interchangeable use with different controller interfaces| US11045270B2|2017-12-19|2021-06-29|Cilag Gmbh International|Robotic attachment comprising exterior drive actuator| US11129680B2|2017-12-21|2021-09-28|Cilag Gmbh International|Surgical instrument comprising a projector| US11076853B2|2017-12-21|2021-08-03|Cilag Gmbh International|Systems and methods of displaying a knife position during transection for a surgical instrument| US10743868B2|2017-12-21|2020-08-18|Ethicon Llc|Surgical instrument comprising a pivotable distal head| CN109984788A|2017-12-29|2019-07-09|江苏风和医疗器材股份有限公司|Knife rest and its surgical incision anastomat| US10779821B2|2018-08-20|2020-09-22|Ethicon Llc|Surgical stapler anvils with tissue stop features configured to avoid tissue pinch| US10856870B2|2018-08-20|2020-12-08|Ethicon Llc|Switching arrangements for motor powered articulatable surgical instruments| US11045192B2|2018-08-20|2021-06-29|Cilag Gmbh International|Fabricating techniques for surgical stapler anvils| US10842492B2|2018-08-20|2020-11-24|Ethicon Llc|Powered articulatable surgical instruments with clutching and locking arrangements for linking an articulation drive system to a firing drive system| US10912559B2|2018-08-20|2021-02-09|Ethicon Llc|Reinforced deformable anvil tip for surgical stapler anvil| US11253256B2|2018-08-20|2022-02-22|Cilag Gmbh International|Articulatable motor powered surgical instruments with dedicated articulation motor arrangements| US11039834B2|2018-08-20|2021-06-22|Cilag Gmbh International|Surgical stapler anvils with staple directing protrusions and tissue stability features| US11083458B2|2018-08-20|2021-08-10|Cilag Gmbh International|Powered surgical instruments with clutching arrangements to convert linear drive motions to rotary drive motions| US11207065B2|2018-08-20|2021-12-28|Cilag Gmbh International|Method for fabricating surgical stapler anvils| USD914878S1|2018-08-20|2021-03-30|Ethicon Llc|Surgical instrument anvil| US11197673B2|2018-10-30|2021-12-14|Covidien Lp|Surgical stapling instruments and end effector assemblies thereof| US11147551B2|2019-03-25|2021-10-19|Cilag Gmbh International|Firing drive arrangements for surgical systems| US11147553B2|2019-03-25|2021-10-19|Cilag Gmbh International|Firing drive arrangements for surgical systems| US11172929B2|2019-03-25|2021-11-16|Cilag Gmbh International|Articulation drive arrangements for surgical systems| US11253254B2|2019-04-30|2022-02-22|Cilag Gmbh International|Shaft rotation actuator on a surgical instrument| US11051807B2|2019-06-28|2021-07-06|Cilag Gmbh International|Packaging assembly including a particulate trap| US11224497B2|2019-06-28|2022-01-18|Cilag Gmbh International|Surgical systems with multiple RFID tags| US11241235B2|2019-06-28|2022-02-08|Cilag Gmbh International|Method of using multiple RFID chips with a surgical assembly| US11259803B2|2019-06-28|2022-03-01|Cilag Gmbh International|Surgical stapling system having an information encryption protocol| US11246678B2|2019-06-28|2022-02-15|Cilag Gmbh International|Surgical stapling system having a frangible RFID tag| US11219455B2|2019-06-28|2022-01-11|Cilag Gmbh International|Surgical instrument including a lockout key| US11234698B2|2019-12-19|2022-02-01|Cilag Gmbh International|Stapling system comprising a clamp lockout and a firing lockout| US20210353293A1|2020-05-12|2021-11-18|Covidien Lp|Surgical stapling device with replaceable staple cartridge|
法律状态:
2018-12-11| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]| 2019-11-19| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]| 2020-11-24| B06A| Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]| 2021-03-23| B09A| Decision: intention to grant [chapter 9.1 patent gazette]| 2021-05-04| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/09/2012, OBSERVADAS AS CONDICOES LEGAIS. |
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申请号 | 申请日 | 专利标题 US13/242,164|US8985429B2|2011-09-23|2011-09-23|Surgical stapling device with adjunct material application feature| US13/242,164|2011-09-23| PCT/US2012/056066|WO2013043694A1|2011-09-23|2012-09-19|Surgical stapling device with adjunct material application feature| 相关专利
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