• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    SURGICAL CLAMP WITH LOCATED AUXILIARY COATING. The present invention relates to a medical fixation device that has a first shape, pre-application, to be loaded onto a surgical instrument and a second shape, post-application, to join tissues, and includes a crown and a pair of legs, each leg extending substantially transversely from the respective end of the crown in the first shape, pre-application. A coating, like a hemostatic agent, is applied to the internal surface of the fixation device, bounded by the internal surfaces of the crown and the pair of legs.
    公开号:BR112014003099B1
    申请号:R112014003099-5
    申请日:2012-08-10
    公开日:2021-01-12
    发明作者:Brian W. Bear；Thu Anh Le；Mark D. Overmyer；Michael Setser；James A. Woodard Jr.
    申请人:Ethicon Endo-Surgery, Inc.；
    IPC主号:
    专利说明:

    [0001] [001] In some contexts, endoscopic surgical instruments may be preferred over devices for traditional open surgery, since a smaller incision can reduce recovery time and complications in the postoperative period. Consequently, some endoscopic surgical instruments may be suitable for placing a distal end actuator in a desired surgical site through the trocar cannula. These distal end actuators can hold the tissue in various ways to achieve a diagnostic or therapeutic effect (for example, cutter, claw, cutter, stapler, clamp applicator, access device, drug / gene therapy delivery device and device for application of energy using ultrasound, RF, laser, etc.). Endoscopic surgical instruments can comprise a rod between the end actuator and a cable portion, which is handled by the physician. This rod can allow insertion to the desired depth and rotation around the longitudinal axis of the rod itself, thus facilitating the positioning of the end actuator on the patient. The positioning of an end actuator can also be facilitated by the inclusion of one or more articulated joints or features, allowing the end actuator to be selectively articulated or even offset in relation to the longitudinal axis of the stem.
    [0002] [002] Examples of endoscopic surgical instruments include surgical staplers. Some of these staplers can be operated to attach layers of fabric, cut through stapled layers of fabric, and insert staples through layers of fabric to securely join the separate layers of fabric near the separate ends of the layers of fabric. Merely exemplary surgical staplers are revealed; US Patent No. 4,805,823, entitled "Pocket Configuration for Internal Organ Staplers", issued February 21, 1989; US Patent No. 5,415,334, entitled "Surgical Stapler and Staple Cartridge", issued May 16, 1995; US Patent No. 5,465,895, entitled "Surgical Stapler Instrument", issued November 14, 1995; US Patent No. 5,597,107, entitled "Surgical Stapler Instrument", issued January 28, 1997; US Patent No. 5,632,432, entitled "Surgical Instrument", issued May 27, 1997; US Patent No. 5,673,840, entitled "Surgical Instrument", issued October 7, 1997; US Patent No. 5,704,534, entitled "Articulation Assembly for Surgical Instruments", issued January 6, 1998; US Patent No. 5,814,055, entitled "Surgical Clamping Mechanism", issued September 29, 1998; US Patent No. 6,964,363, entitled "Surgical Stapling Instrument having Articulation Joint Support Plates for Supporting a Firing Bar", issued on November 15, 2005; US Patent No. 6,978,921, entitled "Surgical Stapling Instrument Incorporating an E-Beam Firing Mechanism", issued December 27, 2005; US Patent No. 6,988,649, entitled "Surgical Stapling Instrument Having a Spent Cartridge Lockout", issued January 24, 2006; US Patent No. 7,000,818, entitled "Surgical Stapling Instrument Having Separate Distinct Closing and Firing Systems", issued February 21, 2006; US Patent No. 7,111,769, entitled "Surgical Instrument Incorporating an Articulation Mechanism having Rotation about the Longitudinal Axis", issued September 26, 2006; US Patent No. 7,143,923, entitled "Surgical Stapling Instrument Having a Firing Lockout for an Unclosed Anvil", issued December 5, 2006; US Patent No. 7,303,108, entitled "Surgical Stapling Instrument Incorporating a Multi-Stroke Firing Mechanism with a Flexible Rack", issued December 4, 2007; US Patent No. 7,367,485, entitled "Surgical Stapling Instrument Incorporating a Multistroke Firing Mechanism Having a Rotary Transmission", issued May 6, 2008; US Patent No. 7,380,695, entitled "Surgical Stapling Instrument Having a Single Lockout Mechanism for Prevention of Firing", issued on June 3, 2008; US Patent No. 7,380,696, entitled "Articulating Surgical Stapling Instrument Incorporating a Two-Piece E-Beam Firing Mechanism", issued on June 3, 2008; US Patent No. 7,404,508, entitled "Surgical Stapling and Cutting Device", issued July 29, 2008; US Patent No. 7,434,715, entitled "Surgical Stapling Instrument having Multistroke Firing with Opening Lockout", issued October 14, 2008; US Patent No. 7,721,930, entitled "Disposable Cartridge with Adhesive for Use with a Stapling Device", issued May 25, 2010; and US Patent No. 7,455,208, entitled "Surgical Instrument with Articulating Shaft with Rigid Firing Bar Supports", issued November 25, 2008. The description of each of the aforementioned US patents is incorporated into the present invention by reference. While the surgical staplers mentioned above are described as being used in endoscopic procedures, it should be understood that such surgical staplers can also be used in open procedures and / or other non-endoscopic procedures.
    [0003] [003] Although various types of surgical stapling instruments and associated components have been produced and used, it is believed that no one before the inventor (s) has produced or used the invention described in the embodiments. Brief Description of Drawings
    [0004] [004] The attached drawings, which are incorporated into this specification and form part of it, illustrate modalities of the invention and, together with the general description provided above, and the detailed description of the modalities provided below, serve to explain the principles of the present invention.
    [0005] [005] Figure 1A represents a perspective view of an articulated surgical instrument with an end actuator in a non-articulated position;
    [0006] [006] Figure 1B represents a perspective view of the surgical instrument of Figure 1A with an end actuator in an articulated position;
    [0007] [007] Figure 2 represents a perspective view of the open end actuator of the surgical instrument of Figures 1A to 1B;
    [0008] [008] Figure 3A represents a side cross-sectional view of the end actuator of Figure 2, taken along line 3-3 of Figure 2, with the firing bar in a proximal position;
    [0009] [009] Figure 3B represents a side cross-sectional view of the end actuator of Figure 2, taken along line 3-3 of Figure 2, but showing the firing bar in the distal position;
    [0010] [0010] Figure 4 represents a cross-sectional view from the end of the end actuator of Figure 2, taken along line 4-4 of Figure 2;
    [0011] [0011] Figure 5 represents an exploded perspective view of the end actuator of Figure 2;
    [0012] [0012] Figure 6 represents a perspective view of the end actuator of Figure 2, positioned on a fabric and having been activated once on the fabric;
    [0013] [0013] Figure 7 represents a perspective view of an exemplary surgical clamp, with auxiliary coating located on the internal surface;
    [0014] [0014] Figure 8 represents a first example of a cross-sectional view of the coated clamp of Figure 7 along line 8-8;
    [0015] [0015] Figure 9 represents a second example of a cross-sectional view of a coated clamp;
    [0016] [0016] Figure 10 represents the coated clamp of Figure 7 inserted in the compressed tissue and holding it; and
    [0017] [0017] Figure 11 represents a flowchart of an example method for coating the inside of a clamp with localized auxiliary coating.
    [0018] [0018] The drawings are not intended to be limiting in any way, and it is envisaged that various embodiments of the invention may be carried out in a variety of other ways, including those not necessarily represented in the drawings. The attached drawings, incorporated and forming a part of the specification, illustrate various aspects of the present invention and, together with the description, serve to explain the principles of the invention; it is understood, however, that this invention is not limited to the specific provisions shown. Detailed Description
    [0019] [0019] The following description of specific examples of the invention should not be used to limit the scope of the present invention. Other examples, characteristics, aspects, modalities and advantages of the invention will become evident to those skilled in the art from the following description, which has an illustrative purpose, one of the best ways contemplated for carrying out the invention. As will be understood, the invention can have other different and obvious aspects, all without departing from the invention. Consequently, drawings and descriptions should be considered as illustrative rather than restrictive. I. Exemplary surgical stapler
    [0020] [0020] Figures 1 to 6 represent a surgical instrument exemplifying stapling and separation (10) that is sized for insertion in an unarticulated state, as shown in Figure 1A, through the canal of the trocar cannula, to a surgical site in one patient, to perform a surgical procedure. The stapling and separation surgical instrument (10) includes a cable portion (20) connected to an implement portion (22), the latter also comprising a rod (23) that ends distally in a hinge mechanism (11) and a end actuator (12) connected distally. When the articulation mechanism (11) and the distal end actuator (12) are inserted through the canal of the trocar cannula, the articulation mechanism (11) can be articulated remotely, as shown in Figure 1B, by controlling articulation (13). Thus, the end actuator (12) can reach behind an organ or approach a tissue at a desired angle or for other reasons. It should be understood that terms such as "proximal" and "distal" are used in the present invention with reference to the handle portion (20) of the instrument (10) handled by the physician. Thus, the end actuator (12) is in a distal position with respect to the most proximal portion of cable (20). It will also be recognized that, for convenience and clarity, spatial terms such as "vertical" and "horizontal" are used in the present invention in connection with the drawings. However, surgical instruments can be used in many orientations and positions, and these terms are not intended to be limiting and absolute.
    [0021] [0021] The end actuator (12) of the present example includes a lower jaw (16) and an articulated anvil (18). The handle portion (20) includes a pistol grip (24), against which a closing trigger (26) is pivotally pressed by the doctor, in order to cause the anvil to grip or close (18) against the lower jaw (16) of the end actuator (12). This closure of the anvil (18) is achieved by means of an external closing sleeve (32), which moves longitudinally in relation to the cable portion (20) in response to the articulated actuation of the closing trigger (26) against the handle of pistol (24). A distal closing ring (33) of the closing sleeve (32) is supported indirectly by the structure (34) of the implement portion (22). In the articulation mechanism (11), a proximal closing tube (35) of the closing sleeve (32) communicates with the distal portion (closing ring) (33). The structure (34) is flexibly connected to the lower jaw (16) via the articulation mechanism (11), allowing articulation in a single plane. The frame (34) also supports, in a longitudinal and sliding way, a firing steering member (not shown), which extends through the rod (23) and transmits a firing movement from the firing trigger (28) to the firing bar. trigger (14). The trigger trigger (28) is furthest from the closing trigger (26), being pressed jointly by the doctor to staple and separate the tissue attached to the end actuator (12), as will be described in more detail below. Then, the release button (30) is released to release the tissue from the end actuator (12).
    [0022] [0022] Figures 2 to 5 represent the end actuator (12) that employs an electronic beam firing bar (14) to perform a variety of functions. As can best be seen in Figures 3A to 3B, the firing bar (14) includes a cross-oriented upper pin (38), a firing cap (44), a cross-oriented middle pin (46) and a cutting edge distal position (48). The upper pin (38) is located and is translatable inside an anvil pocket (40) of the anvil (18). The trigger bar cover (44) slidably engages the lower surface of the lower jaw (16), causing the trigger bar (14) to extend along the groove in the groove (45) (shown in Figure 3B ) that is formed along the lower jaw (16). The middle pin (46) slidably engages the top surface of the lower jaw (16), cooperating with the trigger bar cover (44). Thus, the firing bar (14) positively spaces the end actuator (12) during firing, avoiding the mechanical tightening that can occur between the anvil (18) and the lower jaw (16) with a minimum amount of tissue attached and preventing staple malformation when an excessive amount of tissue is attached.
    [0023] [0023] Figure 2 shows the firing bar (14) positioned proximally and the anvil (18) hinged in an open position, allowing an unsent staple cartridge (37) to be installed in the lower jaw groove (16) removably. As can best be seen in Figures 4 to 5, the staple cartridge (37) of this example includes the cartridge body (70), which contains an upper platform (72) and is coupled to a lower cartridge tray (74). As can be seen better in Figure 2, a vertical slot (49) is formed through part of the staple cartridge (37). Also as can be seen better in Figure 2, three rows of staple openings (51) are formed through the upper platform (70) on one side of the vertical slot (49), with another set of three rows of staple openings (51 ) formed through the upper platform (70) on the other side of the vertical slot (49). Returning to Figures 3 to 5, a wedge-shaped sliding support (41) and a plurality of clamp actuators (43) are comprised between the cartridge body (70) and the tray (74), with the sliding support in the form wedge (41) with location proximal to the clip drivers (43). The wedge sliding support (41) is movable longitudinally inside the staple cartridge (37); whereas the staple actuators (43) are movable vertically inside the staple cartridge (37). The clips (47) are also positioned inside the cartridge body (70), above the corresponding clip drivers (43). In particular, each clamp (47) is inserted vertically into the cartridge body (70) by a clamp driver (43), in order to insert the clamp (47) through an associated clamp opening (51). As can best be seen in Figures 3A to 3B and 5, the wedge-shaped sliding support (41) has inclined cam surfaces that push the clamp actuators (43) upwards, according to the wedge-shaped sliding support (41) ) is inserted distally through the staple cartridge (37).
    [0024] [0024] With the end actuator (12) closed, as shown in Figure 3A, the firing bar (14) is advanced engaged with the anvil (18) through the entrance of the upper pin (38) in a longitudinal slot of the anvil ( 42). A drive block (80) is located at the distal end of the firing bar (14) and is configured to engage the wedge-shaped sliding bracket (41) so that the wedge-shaped sliding bracket (41) is pushed distally by the drive block (80) as the firing bar (14) is advanced distally through the staple cartridge (37). During this firing, the cutting edge (48) of the firing bar (14) enters the vertical slot (49) of the staple cartridge (37), separating the tissue trapped between the staple cartridge (37) and the anvil (18). As shown in Figures 3A to 3B, the middle pin (46) and the drive block (80), together, activate the staple cartridge (37) by entering a firing slot inside the staple cartridge (37), the which leads the wedge-shaped sliding support (41) to the upward contact of the cam with the clamp actuators (43), which, in turn, impel the clamps (47) through the clamp openings (51) and to the forming contact with the staple formation cavities (53) on the inner surface of the anvil (18). Figure 3B represents the firing bar (14) completely translated distally after the separation and stapling of the fabric are completed.
    [0025] [0025] Figure 6 shows the end actuator (12) driven by a single movement through the fabric (90). As shown, the cutting edge (48) cut the fabric (90), while the staple drivers (43) triggered three alternating rows of staples (47) through the fabric (90) on both sides of the cutting line produced by the edge cutting (48). The clamps (47) are all oriented substantially parallel to the cut line in this example, although it should be understood that the clamps (47) can be positioned in any suitable orientations. In the present example, the end actuator (12) is removed from the trocar after the first movement is complete, the staple cartridge sent (37) is replaced by a new staple cartridge, and the end actuator (12) is again inserted through the trocar to reach the stapling site for additional cuts and stapling. This process can be repeated until the desired number of cuts and staples (47) has been applied. The anvil (18) may need to be closed to facilitate insertion and removal through the trocar; and the anvil (18) may need to be opened to facilitate replacing the staple cartridge (37).
    [0026] [0026] It should be understood that the cutting edge (48) can separate fabrics substantially at the same time that the clips (47) are inserted through the fabric during each actuation movement. In the present example, the cutting edge (48) closely follows the insertion of the clips (47), so that a clip (47) is inserted through the fabric just before the cutting edge (48) passes through the same region of the fabric, although it should be understood that this order can be reversed, or that the cutting edge (48) can be directly synchronized with the adjacent clips. Although Figure 6 shows the end actuator (12) being driven in two layers (92, 94) of fabric (90), it should be understood that the end actuator (12) can be driven through a single layer of fabric (90) or more than two layers (92, 94) of fabric. It should also be understood that the formation and positioning of staples (47) adjacent to the cutting line produced by the cutting edge (48) can substantially unite the fabric at the cutting line, thereby reducing or preventing bleeding and / or leakage other body fluids on the cut line. Various suitable configurations and procedures in which the instrument (10) can be used will be apparent to those skilled in the art in view of the teachings contained herein.
    [0027] [0027] It should be understood that the instrument (10) can be configured and is operable in accordance with any other teachings of US patent No. 4,805,823; US patent No. 5,415,334; US patent No. 5,465,895; US patent No. 5,597,107; US patent No. 5,632,432; US patent No. 5,673,840; US patent No. 5,704,534; US patent No. 5,814,055; US patent No. 6,964,363; US patent No. 6,978,921; US patent No. 6,988,649; US patent No. 7,000,818; US patent No. 7,111,769; US patent No. 7,143,923; US patent No. 7,303,108; US patent 7,367,485; US patent 7,380,695; US patent No. 7,380,696; US patent No. 7,404,508; US patent No. 7,434,715; US patent No. 7,721,930; and / or US patent No. 7,455,208. As noted above, the descriptions of each of these patents are incorporated by reference to the present invention. Additional exemplary modifications that can be made to the instrument (10) will be described in more detail below. Several suitable ways in which the teachings below can be incorporated into the instrument (10) will be apparent to those skilled in the art. Similarly, various ways in which the teachings below can be combined with various teachings of the patents cited herein will be apparent to those skilled in the art. It should also be understood that the teachings below are not limited to the instrument (10) or the devices taught in the patents cited here. The teachings below can be readily applied to several other types of instruments, including instruments that would not be classified with surgical staplers. Various other suitable devices and configurations in which the teachings below can be applied will be apparent to those skilled in the art in view of the teachings contained herein. II. Exemplary internally coated surgical clamp
    [0028] [0028] Figure 7 shows an exemplary surgical clamp (100), coated with an auxiliary coating located (104) on a rough internal surface (102). The surgical clamp (100) can have a triangular metallic structure, as shown in Figure 8; rectangular metallic structure, as shown in Figure 9; or metallic structure with any other format, as will be understood by those versed in the technique in view of the teachings contained herein. The surgical clamp (100) includes a crown (106) with ends, each substantially transversely and perpendicularly extending the respective leg of a pair of legs (108) when the clamp (100) is in a first format, pre-application. The crown (106) and the pair of legs (108) comprise a material selected from at least one among iron, nickel – titanium alloy, stainless steel or titanium. Obviously, any other suitable material or combination of materials can be used.
    [0029] [0029] When the surgical clamp (100) is inserted into the tissue by a surgical instrument, such as by the instrument (10) in the manner presented above, the surgical clamp (100) will compress, connect and support such tissue as shown in Figure 10. In second format, post-application, shown in Figure 10, each of the legs (108) is bent towards the other so that they form an arc around the top surface of an upper layer of fabric (90) and penetrate the surface of top of the fabric (90), while the crown (106) pinches a bottom surface of a lower fabric layer (90), allowing the crown (106) and the legs (108) of the clamp (100) to compress, connect and support the tissue layers (90) after the clamp (100) is applied by the instrument (10). The inner lining (104) of the surgical clamp (100) will contact the compressed tissue and act on the tissue to assist in its repair, for example, acting as a hemostatic agent and allowing blood to clot, which reduces the volume of the blood. bleeding at the surgical site.
    [0030] [0030] An exemplary method of forming the exemplary clamp of Figure 7 is shown in Figure 11. The metallic structure of the clamp (100) is formed (110) according to processes known to those skilled in the art, such as those described, only as a title for example, for at least some of the teachings of US patent No. 6,638,297, entitled "Surgical Staple", granted on October 28, 2003, the description of which is incorporated by reference to the present. The internal or internal surface (102) of the metal surface of the clamp (100) is wrinkled (112) by a forming anvil, for example, which can act in a stamping process to wrinkle the internal surface (102). As another illustrative example, an intermediate coating can be applied to the inner surface (102) to provide the crease. For example, such an intermediate coating may include shot. Suitable materials for such an intermediate coating will be apparent to those skilled in the art in view of the teachings contained herein. Other processes for wrinkling the internal surface (102) may include compression forming operations, drawing operations and / or alternative grinding operations, for example, in addition to other metal forming processes and / or chemical wrinkling processes, apparent to those skilled in the art, in view of the teachings contained herein to wrinkle metal surfaces, all of which are within the scope of this description.
    [0031] [0031] A secondary molding process is used to inject (114) a paste into the rough internal surface (102) of the clamp (100). The paste may comprise, for example, a bovine collagen paste or other auxiliary compound. For example, fibrin or thrombin can be used. The hemostatic capabilities of these auxiliary compounds can also contribute to the use of these auxiliary compounds as adhesives and sealants. The agents can help to clot blood at the surgical site, which allows the tissue surrounding the blood to remain joined and prevent leaks along the stapled tissue site, for example.
    [0032] [0032] Such auxiliary compounds or reagents may include, but are not limited to: medicinal fluid or pasty components capable of being applied to the internal surface (102) of the clamp (100) and then being heated to form a dry coating, as described below, such as thrombin, platelet-poor plasma (PPP), platelet-rich plasma (PRP), starch, chitosan, alginate, fibrin, polysaccharide, cellulose, collagen, bovine collagen, gelatin-resorcin-formalin adhesive, oxidized cellulose, adhesive to mussel based, poly (amino acid), agarose, amylose, hyaluronan, polyhydroxybutyrate (PHB), hyaluronic acid, poly (vinyl pyrrolidone) (PVP), poly (vinyl alcohol) (PVA), polylactide (PLA), polyglycolate (PGA) , polycaprolactone (PCL) and its copolymers, VICRYL® (Ethicon, Inc., Somerville, NJ, USA), MONOCRYL material, PANACRYL (Ethicon, Inc., Somerville, NJ, USA) and / or and any other material suitable for mixed with biological material and introduced into a wound the u problem site, including material combinations. Other components, materials, substances etc. suitable materials that can be used in a medicinal fluid or paste will be apparent to those skilled in the art in view of the teachings contained herein.
    [0033] [0033] In some versions, a medical fluid can be suspended in a biocompatible vehicle. Suitable vehicles may include, for example, a physiological buffer solution, a high flow gel solution, saline, and water. In the case of gel solutions, the tissue repair composition may be in a high-flow gel form prior to release to the target site, or it may form a gel and remain in place after release to the target site. High-flow gel solutions may comprise one or more gelling materials with or without the addition of water, saline, or physiological buffer solution. Suitable gelling materials include biological and synthetic materials. Exemplifying gelling materials include the following: proteins such as collagen, collagen gel, elastin, thrombin, fibronectin, gelatin, fibrin, tropoelastine, polypeptides, laminin, proteoglycans, fibrin glue, fibrin clot, platelet-rich plasma clot (PRP) , platelet-poor plasma clot (PPP), self-assembled peptide hydrogels, Matrigel or atelocolagen; polysaccharides such as pectin, cellulose, oxidized regenerated cellulose, chitin, chitosan, agarose, or hyaluronic acid; polynucleotides such as ribonucleic acids or deoxyribonucleic acids; other materials include alginate, cross-linked alginate, poly (N-isopropylacrylamide), poly (oxyalkylene), copolymers of poly (ethylene oxide) -poly (propylene oxide), poly (vinyl alcohol), polyacrylate, or mono-stearoyl glycerol cossuccinate copolymers / polyethylene glycol (MGSA / PEG); and combinations of any of the previously mentioned. In addition to providing a high flow vehicle solution for tissue fragments, a gelling agent (s) can also act as an adhesive that anchors the tissue repair composition to a target site. In some versions, an additional adhesive anchoring agent may be included in the medical tissue or fluid repair composition. Also, one or more crosslinking agents can be used in conjunction with one or more gelling agents to crosslink the gelling agent.
    [0034] [0034] Returning to Figure 11, the clamp (100), including the injected paste, is then heated (116) to evaporate the solvent from the paste, resulting in the dry coating (104) of the auxiliary compound that is located on the surface (102) of the clamp (100). The coated clamp (100) is then inserted (118) into a cartridge, like the cartridge (37) described above, for use with an instrument capable of inserting the clamp (100) through the fabric (like the fabric (90) shown in Figure 6). Although only one coating (104) is shown in this specific example, it should be understood that more than one coating (104) can be applied. For example, the inner surface (102) can receive several coatings (104) of the same material and / or different coatings of different materials (104). As an illustrative example, the inner surface can receive a first coating (104) with therapeutic or coagulating agent; then a second coating (104) that protects the first coating (104), with the second coating (104) being configured to disintegrate upon getting wet, to thereby protect the first coating (104) until the clamp (100) is applied on the fabric. It should be understood that the layers of the coatings (104) can provide compliance or expandability to the bioreagents, resulting in the application of residual pressure (for example, on a microscale) to the adjacent tissue. Other suitable selections, properties and combinations of coatings (104) will be apparent to those skilled in the art in view of the teachings contained herein.
    [0035] [0035] In use, as the surface of the clamp (100) is not completely coated, but, on the contrary, the coating (104) is located and is applied to the internal surface (102) of the clamp (100), the clamp ( 100) will preserve a diameter such that the clamp (100) fits into the existing cartridge clamp cavity (37), for example, which is also used for the clamps (47), as described above. In addition, the located inner lining (104) of the clamp (100) can help to reduce the friction that would occur in the case of a fully clad clamp, which could contribute to the problems of forming the clamp and increasing the force required to fire the clamps. staples through the fabric. In addition, less losses can occur with the inner lining located (104) described here. With a fully coated clamp, the contact between the cartridge (37) and the anvil (18) can cause the coating on the external surfaces of the clamp to be prematurely removed and expelled on the instrument (10) instead of on the fabric (90), for example.
    [0036] [0036] It must be understood that any one or more of the teachings, expressions, modalities, examples, etc. described here can be combined with any one or more of the other teachings, expressions, modalities, examples, etc. that are described here. The teachings, expressions, modalities, examples, etc., described below, should therefore not be seen in isolation from each other. Various suitable ways in which the teachings of the present invention can be combined will be readily apparent to those skilled in the art in view of the teachings of the present invention. It is understood that these modifications and variations are included in the scope of the embodiments.
    [0037] [0037] Versions of the devices described above may have application in conventional medical treatments and procedures conducted by a medical professional, as well as application in medical treatments and procedures assisted by robotics.
    [0038] [0038] Versions of the above can be designed to be discarded after a single use, or can be designed for use multiple times. The versions can, in either or both cases, be reconditioned for reuse after at least one use. Reconditioning can include any combination of steps to disassemble the device, followed by cleaning or replacing particular parts and subsequent reassembly. In particular, some versions of the device can be disassembled, and any number of particular parts or parts of the device can be selectively replaced or removed in any combination. With the cleaning and / or replacement of particular parts, some versions of the device can be reassembled for subsequent use in a reconditioning facility or by a user immediately prior to a surgical procedure. Those skilled in the art will understand that the reconditioning of a device can use a variety of techniques for disassembly, cleaning / replacement and reassembly. The use of such techniques, and the resulting refurbished device, are all within the scope of the present application.
    [0039] [0039] Just as an example, the versions described here can be sterilized before and / or after a procedure. In a sterilization technique, the device is placed in a closed and sealed container, such as a plastic or TYVEK bag. The container and the device can then be placed in a radiation field, such as gamma radiation, X-rays or high-energy electrons, which can penetrate the container. Radiation can kill bacteria on the device and the container. The sterile device can then be stored in a sterile container for later use. The device can also be sterilized using any other known technique, including, but not limited to beta or gamma radiation, ethylene oxide or water vapor.
    [0040] [0040] In view of the presentation and description of various versions in the present disclosure, additional adaptations of the methods and systems described in this document can be made through appropriate modifications made by an element versed in the technique without departing from the scope of the present invention . Several of these possible modifications have been mentioned, and others will be evident to the elements versed in the technique. For example, the examples, versions, geometry, materials, dimensions, proportions, steps and the like discussed above are illustrative only and are not mandatory. Consequently, the scope of the present invention must be considered in accordance with the terms of the embodiments, and it is understood that it is not limited to the details of the structure and operation shown and described in the specification and drawings.
    权利要求:
    Claims (15)
    [0001]
    Medical fixation device (100) with a first format, pre-application, for loading into a surgical instrument (10) and a second format, post-application, for joining tissues, the fixation device (100) comprising: (a) a crown (106), including a pair of ends; (b) a pair of legs (108), each leg (108) extending transversely from a respective end of the crown (106) in the first shape, pre-application; (c) an internal surface of the fixing device (102), bounded by internal surfaces of the crown (106) and the pair of legs (108); (d) an outer surface of the fixing device, bounded by outer surfaces of the crown (106) and the pair of legs (108); and characterized by the fact that: (e) at least one coating (104) of a tissue repair composition is applied only to the inner surface of the crown (106) and the pair of legs (108), where the outer surface of the fixture is not coated.
    [0002]
    Clamping device (100) according to claim 1, characterized in that the clamping device (100) in the first shape, pre-application, has a rectangular cross-sectional shape or a triangular cross-sectional shape.
    [0003]
    Fixation device (100) according to claim 1, characterized in that the coating (104) comprises at least one of a hemostatic agent, a sealant or an adhesive.
    [0004]
    Fixation device (100) according to claim 1, characterized in that the coating (104) comprises fibrin or thrombin.
    [0005]
    Fixation device (100) according to claim 1, characterized in that the coating (104) comprises a paste of bovine collagen.
    [0006]
    Fixing device (100) according to claim 1, characterized by the fact that the internal surface is rough.
    [0007]
    Fixation device (100) according to claim 1, characterized in that the crown (106) and the pair of legs (108) comprise a material selected from at least one of the following materials: iron, nickel alloy -titanium, stainless steel and titanium.
    [0008]
    Fixing device (100) according to claim 1, characterized in that the coating (104) is a paste when it is applied to the internal surface of the fixing device (102).
    [0009]
    Fixing device (100) according to claim 1, characterized in that the coating (104) is dry coating after application to the internal surface of the fixing device (102).
    [0010]
    Fixation device (100) according to claim 1, characterized in that the coating (104) can react with a tissue when the medical fixation device (100) is in the second shape, post-application, to join the fabrics.
    [0011]
    Method characterized by the fact that it is to form the fixation device (100) as defined in claim 1 by coating a preformed medical fixation device with a first shape, pre-application, to load in a staple cartridge (37) a surgical instrument (10) and a second format, post-application, to join tissues, the method comprising the steps of: (a) wrinkling an internal surface of the fixing device (102); (b) injecting material into the rough internal surface (102); (c) heat the injected material; and (d) insert the fixing device (100) being a coated clamp (100) in the clamp cartridge (37).
    [0012]
    Method according to claim 11, characterized in that the step of heating the injected material comprises the evaporation of solvent from the material and the creation of a dry coating.
    [0013]
    Method according to claim 11, characterized in that the fixing device (100) comprises a crown (106) and a pair of legs (108), each leg (108) extending transversely from the respective crown end (106) in the first shape, pre-application.
    [0014]
    Method according to claim 11, characterized by the fact that the step of injecting the material into the rough internal surface (102) comprises the injection of hemostatic agent into the rough internal surface (102).
    [0015]
    Surgical instrument (10) characterized by the fact that it comprises a portion of handle (20), a rod (23) that houses a firing bar (14), an end actuator (12) that comprises an anvil (18), an lower jaw (16) and a stapling and separation mechanism responsive to a longitudinal closing movement produced by the cable portion (20) and the stem (23), in which the lower jaw (16) is configured to receive a cartridge (37 ) when in the open position, where the cartridge (37) comprises: (a) an accommodation; (b) a plurality of clamps (47) arranged in the housing, each clamp (47) with a first shape, pre-application, for loading into a surgical instrument (10) and a second shape, post-application, for joining the tissues , each clamp (47) according to the fixing device (100) as defined in claim 1; wherein the stapling and separation mechanism is operable to drive the plurality of staples (47) towards the anvil (18) to form the second shape, post-application, of each staple.
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    公开号 | 公开日
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    法律状态:
    2018-12-11| B06F| Objections, documents and/or translations needed after an examination request according art. 34 industrial property law|
    2019-10-29| B06U| Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure|
    2020-11-03| B09A| Decision: intention to grant|
    2021-01-12| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/08/2012, OBSERVADAS AS CONDICOES LEGAIS. |
    优先权:
    申请号 | 申请日 | 专利标题
    US13/206,725|2011-08-10|
    US13/206,725|US20130041406A1|2011-08-10|2011-08-10|Surgical staple with localized adjunct coating|
    PCT/US2012/050226|WO2013023111A2|2011-08-10|2012-08-10|Surgical staple with localized adjunct coating|
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