• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    FOLDING VALVE, NEEDLE-FREE ACCESS DEVICE AND METHOD FOR MANUFACTURING A NEEDLE-FREE ACCESS DEVICE, which provide for a folding valve comprising a first portion with at least one cavity on one side of it, and a second portion, the second portion being The portion is narrower than the first portion and is arranged along an axial dimension of the first portion, the second portion of which includes a cut within it.
    公开号:BR112012001634B1
    申请号:R112012001634-2
    申请日:2010-02-22
    公开日:2021-01-19
    发明作者:George M. Mansour；James Bennett
    申请人:Carefusion 303, Inc.；
    IPC主号:
    专利说明:

    TECHNICAL FIELD
    [0001] The present application for a patent relates, generally, to devices for fluid flow and, more specifically, to valves for use in medical devices. BACKGROUND OF THE INVENTION
    [0002] Needle-free access devices allow a healthcare professional, for example, to replace / add IV bags, and / or access an IV line without having to use a needle. Figure 1 is a cross-sectional view of a current needle-free access device 100. The needle-free access device 100 includes a female luer fitting 101, a male luer fitting 102, and valve 103. When in use, the fitting male luer 102 is connected, for example, to a catheter or female luer and the female luer fitting 101 is connected to a fluid reservoir. The female luer fitting 101 is connected to the fluid reservoir via a second male luer fitting (not shown) that includes a hollow member inserted through the top of the female luer fitting 101, smaller collapse valve 103 in volume 104 for break the seal and create a path for the flow of the fluid. The hollow member of the second male luer fitting carries the fluid, which flows around the valve 103 in channels (not shown) in the male luer fitting 102 and the catheter or female luer.
    [0003] The internal valve 103 is a gap (or septum, not shown) that is filled with air. The device 100 is a positive displacement device, so that when a new connection is made to the female luer fitting 101, the device 100 pulls the fluid from the male side of the valve, (ie, the side close to the male luer fitting) 102). When disconnection is made in the female luer fitting 101, the device 100 pushes the liquid from the female side (i.e., on the side near the top of the female luer fitting 101). The advantage of positive displacement is that when a disconnection is made, the device 100 expels fluid out of the male luer socket 102 and effectively flushes the catheter. On the other hand, many devices on the market today have negative displacement, so that when a syringe is disconnected, that device pulls some fluid from the side of the male luer, in which, if a catheter is being used, it means that the blood is pulled into the lumen of the catheter. The blood that is left in the lumen of the catheter can clot and cause health problems for the patient.
    [0004] An additional feature of device 100 is that when the female end is accessed by a male luer (not shown), valve 103 is elastic so that it can bend out of the way to allow flow and then return to its original shape after a disconnection is made at the female end. In this way, the device 100 reseals and forms a flat surface that can be disinfected on the upper surface 110 using an alcohol swab. On the other hand, many devices on the market use plastic valves that cannot flex to get out of the way to allow flow, thus requiring the use of valves that are tilted or incorporating features in the upper portion, making cleaning difficult. alcohol.
    [0005] Device 100 has a symmetrical valve body providing symmetrical wall strength, as well as points of weakness on both sides due to duck nozzles 105. The contact area between a luer and the top surface 110 of the valve 103 and the type of movement of the luer will dictate the folding shape of the valve body. The device 100 provides good performance, but could benefit from greater repeatability and controllability of the fold. BRIEF SUMMARY OF THE INVENTION
    [0006] Various configurations of the invention are directed to valves and needle-free access devices using folding valves, which include a cut and at least one cavity to cause specific behavior of the folding valve. In a specific example, a cut is placed in an upper part of a valve, the upper part being narrower in diameter than in a lower part and forming the upper seal of a needle-free access device. The lower part is substantially cylindrical, forming a septum and including at least one cavity in it. The cavity is angularly displaced from the cut by approximately ninety degrees, enough that a load point on the top surface of the valve is displaced from the cut to delay the collapse of the cut and result in less frontal fall from the top when the cut collapses . A method according to a configuration that is related to processes for the manufacture of needle-free access devices. Another configuration refers to a needle-free access device that includes a foldable valve.
    [0007] The foregoing has been outlined more broadly for the characteristics and technical advantages of the present invention, so that the following detailed description of the invention can be better understood. The additional features and advantages of the invention will be described below, which are the subject of the claims of the invention. It should be appreciated by those skilled in the art that the specific design and configuration disclosed can be easily used as a basis for modifying or creating other structures to achieve the same purposes as the present invention. It must also be realized by those skilled in the art that such equivalent constructions do not depart from the spirit and scope of the invention, as set out in the appended claims. The unpublished features which are believed to be characteristic of the invention, as far as their organization and method of operation, together with the objects and additional advantages will be better understood from the description that follows when considered in connection with the accompanying figures . It should be expressly understood, however, that each of the figures is intended for the purpose of illustration and description only and is not intended to be a definition of the limits of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS
    [0008] For a more complete understanding of the present invention, reference is now made to the following descriptions taken in conjunction with the accompanying drawings, in which: Figure 1 is a sectional view of a current needle-free access device; Figures 2A and 2B are a sectional view illustrating an exemplary needle-free access device adapted according to a configuration of the invention; Figures 3A to 3C show views of a valve alone; Figures 4A and 4B show ninety degree views of figures 3A and 3B; Figure 5 is an illustration of an exemplary needle-free access device with a syringe inserted in it and the fold of an exemplary valve; Figures 6A to 6D illustrate the behavior of a specimen valve, as a certain pressure is applied with a syringe, but before bending, according to the configurations of the invention; Figures 7A to 7D illustrate the behavior of an exemplary valve, as a certain pressure is applied with a syringe, but before bending, according to the configurations of the invention; Figure 8 is an illustration of a scenario of using an exemplary valve; and Figures 9A-9C show three examples of a wide variety of cuts that can be applied to some configurations of the invention. DETAILED DESCRIPTION OF THE INVENTION
    [0009] Figures 2A and 2B are sectional views illustrating an exemplary needle-free access device adapted according to a configuration of the invention; The view in Figure 2B is rotated ninety degrees from that shown in Figure 2A.
    [0010] Device 200 includes a female luer fitting 201, male luer fitting 202, and a valve 210. Valve 210 includes a cut 211, which in this example is referred to as a "smiley cut." Valve 210 also includes cavities 212 and 213 on the outside of its lower portion and positioned with axial and angular displacement so that the body of valve 210 is not symmetrical. While the 211 cut is referred to as a cut, it can be manufactured using any of a variety of techniques, including molding, so that a cut is not actually manufactured. An example of a material that can be used for male and female luer fittings 201 and 202 is polycarbonate, and an example of a material that can be used for valve 210 is silicone, despite any of the varieties of suitable materials as well can be used in various configurations.
    [0011] Device 200 provides for positive and self-healing displacement, similar to the device shown in Figure 1. The male luer fitting 202 at the bottom connects to a catheter or other medical device (not shown) that is connected to the body of the patient. A syringe (not shown) connects with the female luer fitting 201 to the folding valve 210 for the cavity defined between the male and female luer fitting 201 and 202. The fluid flow goes from the top of the device 200, around the valve 210, and through channels 230, 240 to the intermediate channel 250 of the male luer fitting 202. Valves 260 and 270 allow air to enter and exit the septum 215 of valve 210.
    [0012] When closed, valve 210 provides two seals. The first seal is on the upper surface 280 of the device 200. The second seal is on the shoulder 290. As explained in more detail with respect to Figure 5, the insertion of a syringe into the female luer fitting 201 folds the valve 210, thus breaking the fences. The valve 210 works like a spring, so that when it is pressed down, it collapses, and when the force is removed, it returns to its original shape and returns to the seal. Generally, the thicker the wall of valve 210, the greater the force of the spring and the thinner the wall, the lower the force of the spring. Therefore, the thickness of the wall affects the characteristic, such as the ease of insertion and displacement of the syringe. In a particular example where valve 210 is approximately two centimeters long, the wall thickness within the range of 0.07 and 0.010 centimeters allows for acceptable displacement, sealing and ease of use. Of course, in cavities 212 and 213 the wall thickness is less, as can be seen especially well in figure 3A.
    [0013] In one example, the device 200 is manufactured by separately molding the valve 210 and the male and female luer fittings 201 and 202. The valve 210 is then positioned in the cavity that is formed by the male and female luer fittings 201 and 202 The male and female luer fittings 201 and 202 are positioned and welded. The device 200 is then sterilized and packaged. Other methods for manufacturing are possible, for example, by gluing instead of soldering male and female luers 201 and 202, and are within the scope of configurations.
    [0014] Figures 3A to 3C show views of a valve 210 by itself. Figure 3B shows a side view, Figure 3A shows a sectional view, and FIGURE 3C shows a bottom view of valve 210. As can be seen, both the top and bottom of valve 210 are annular (in this case , substantially cylindrical), where the upper part includes the smiley cut 211, and the lower part includes cavities 212 and 213. The lower part of valve 210 is substantially hollow, defining a septum 215. Figures 4A and 4B show views in ninety degrees of Figures 3A and 3B.
    [0015] Figure 5 is an exemplary illustration of device 200, with 510 exemplary syringes inserted in it and folding valve 210. The smiley cut 211 collapses, tilting its upper surface 216 to release fluid flow out of the syringe 510. The bottom of valve 210 also collapses, aided by cavities 212 and 213, which function as two weak points, positioned to cause the lower portion to collapse before the smiley cut 211 collapses. Arrows are added to Figure 5 to illustrate a fluid path as it flows through syringe 510, around valve 210, and out of male luer 202.
    [0016] In the configurations shown in Figures 2 to 5, the smiley cut 211 is positioned in relation to cavities 212 and 213 to facilitate the specific collapse behavior. Figures 6A to 6D illustrate the behavior of the 210 valve, as some pressure is applied by the syringe 510, but before it collapses. In the configuration of figures 2 to 6, the cavity 213 is positioned ninety degrees clockwise from the smiley cut 211, which positions the load point 610 counterclockwise to the smiley cut 211 (clockwise and counterclockwise) in which they refer to the orientation shown in FIGURES 2 to 6, in which the valve 210 is shown with the smiley cut 211 above the cavities). The positioning of the charging point 610 is notable because a male luer fitting (not shown) associated with the syringe 510 has a wire to connect with the female luer fitting 201, thus rotating the syringe 510, since it is inserted (and in turn, putting rotational pressure on valve 210). As cavity 213 begins to collapse, pressure point 610 appears ninety degrees from smiley cut 211, where the upper side of valve 210 is stronger than the same directly above smiley cut 211. In this configuration, the smiley cut 211 collapses later than when in a scenario where charge point 610 is placed directly over the smiley cut 211.
    On the contrary, Figures 7A and 7B illustrate the behavior of a valve 710, as a certain pressure is applied with a syringe, but before bending, according to the configurations of the invention. On valve 710, smiley cut 211 is 180 degrees from cavity 213 and directly above cavity 212. Such positioning of cavities 212, 213 and smiley cut 211 causes pressure point 720 to be directly above smiley cut 211, making with the smiley cut 211 collapsing earlier than it would in the scenario illustrated in Figures 6A to 6D.
    [0018] In many utilities, valves 210 and 710 are acceptable alternatives. However, in scenarios where the syringe 510 includes a counter-recess, the early collapse of the smiley cut 211 can cause the upper part of the valve 710 to fall forward and lodge in the recess, somewhat preventing fluid flow. Such a scenario is shown in Figure 8, where the upper part of valve 710 is shown in recess 820 of syringe 810. On the other hand, valve 210 delays the collapse of the smiley cut 211, providing a more vertical collapse of the smiley cut 211 and avoiding the blocking of the syringe recesses. Thus, in scenarios where the syringe includes a recess, the 2010 valve can be used successfully. Valves 210 and 710 can be used successfully in applications using a syringe, as shown in Figures 5 to 7. Various configurations can use any angular displacement of a cavity relative to a cut, with valves 210 and 710 illustrating two examples.
    [0019] While valves 210 and 710 are shown with two cavities each, several configurations are not so limited. For example, more cavities can be added, and some configurations can include only one cavity. In addition, the settings are not limited to the use of smiley cuts, and other shapes of cuts can be used. For example, Figures 9A to 9C show the V 910 cut, U 920 cut, and “seagull” cut 930, which are just three examples of a wide variety of cuts that can be applied to the configurations.
    [0020] As shown above, several configurations include valves with upper surfaces that facilitate flow around, rather than flow through, such valves. Such features provide advantages over configurations that use hard plastics, do not have flat surfaces, and / or allow flow through, rather than around the valves. For example, valves 210 and 710 of the configurations described above provide positive displacement and are self-cleaning, thus providing better hygiene than negative displacement devices. In addition, the upper flat surfaces of valves 210 and 710 can provide better cleaning than devices with sloped or grooved top surfaces, again providing better hygiene quality. Also, the cavities and cuts shown in the configurations above provide somewhat predictable collapse (bending) of the valves, and (especially in the case of valve 210) applicability to any of the syringe varieties.
    [0021] Although the present invention and its advantages have been described in detail, it should be understood that various changes, substitutions and changes can be made here without departing from the spirit and scope of the invention, as defined by the appended claims. In addition, the scope of the present patent application is not intended to be limited to the particular configurations of the process, machine, fabrication, composition of matter, means, methods and steps described in the specification. As one of the skilled professionals in the art will readily appreciate the disclosure of the present invention, processes, machines, manufacturing, material compositions, means, methods, or steps, currently existing or that will be further developed that perform substantially the same function or achieve substantially the same As a result, the corresponding configurations described herein can be used in accordance with the present invention. Accordingly, the appended claims are intended to include within its scope such processes, machines, manufacturing, material compositions, means, methods or steps. Figure Legend Figure 1 1) Fluid reservoir 2) Catheter Figure 2A 1) Fluid reservoir 2) Catheter
    权利要求:
    Claims (24)
    [0001]
    1. "FOLDING VALVE", for a needle-free access device (200), the folding valve (210) comprising: a first portion, comprising a cylindrical wall that forms a septum (215) in it and a cavity (212, 213) on one side of the cylindrical wall; and a second portion, the second portion being narrower than the first portion and arranged along an axial dimension of the first portion, the second portion including a cut (211) on a first side of the second portion, the cut being angularly displaced from the cavity; characterized by a second side of the second portion being stronger than the first side and, when rotating pressure is exerted on the valve (210), the cavity (212; 213) begins to bend, so that a pressure point (610) is formed in the second portion, the pressure point (610) being angularly displaced from the cut (211) on the respective first side, such that the cut folds after the cavity.
    [0002]
    2. "FOLDING VALVE" according to claim 1, characterized in that the cut (211) is angularly displaced from the cavity (212, 213) by 90 degrees.
    [0003]
    3. "FOLDING VALVE", according to claim 1, characterized in that the cavity (212, 213) is positioned clockwise with respect to the cut (211).
    [0004]
    4. "FOLDING VALVE" according to claim 1, characterized in that the first portion is cylindrical.
    [0005]
    5. "FOLDING VALVE", according to claim 1, characterized in that it is installed in an access device without needles (200).
    [0006]
    6. "FOLDING VALVE", according to claim 5, characterized by providing a positive displacement.
    [0007]
    7. "FOLDING VALVE" according to claim 5, characterized in that the second portion has a flat upper part that seals the flow with an upper surface of the needle-free access device (200).
    [0008]
    8. "FOLDING VALVE" according to claim 1, characterized in that it comprises silicone.
    [0009]
    9. "FOLDING VALVE" according to claim 1, characterized in that the first and second portions are annular.
    [0010]
    10. “ACCESS DEVICE WITHOUT NEEDLES”, characterized by having: a female fitting (201); a male socket (202) coupled to the female socket, the male and female inserts define an internal volume; and a foldable valve (210), as defined in any one of claims 1 to 9, disposed within the internal volume.
    [0011]
    11. "NEEDLE-FREE ACCESS DEVICE" according to claim 10, characterized in that the second portion forms a seal in the female socket (201), creating a flat and upper surface (280) of the female socket (201).
    [0012]
    12. "NEEDLE-FREE ACCESS DEVICE" according to claim 10, characterized in that the folding valve (210) provides a positive displacement.
    [0013]
    13. "NEEDLE-FREE ACCESS DEVICE" according to claim 10, characterized in that the male and female fittings (201, 202) are luer type fittings.
    [0014]
    14. "NEEDLE-FREE ACCESS DEVICE" according to claim 10, characterized in that the second portion of the folding valve (210) is cylindrical.
    [0015]
    15. "METHOD FOR MANUFACTURING A NEEDLE-FREE ACCESS DEVICE", a device defined according to claims 10 to 14, the method comprising: arranging a folding valve (210) within a volume defined by a male fitting (202) and a fitting female (201), so that a first portion of the folding valve that is close to the female fitting provides a seal at the opening of the female fitting, the folding valve having a first portion and a second portion axially disposed with each other, the second portion including a cavity (212, 213) on a respective side, the cavity radially displaced from a cut (211) on a first side of the second portion; characterized in that a second side of the second portion is stronger than the first side and, when rotating pressure is exerted on the valve (210), the cavity (212, 213) begins to bend, so that a pressure point (610) is formed in the second portion, the pressure point (610) being angularly displaced from the cut (211) on the respective respective side, such that the cut folds after the cavity.
    [0016]
    16. "METHOD FOR MANUFACTURING A NEEDLE-FREE ACCESS DEVICE", according to claim 15, characterized by further comprising: sterilizing and packaging the needle-free access device (200).
    [0017]
    17. "METHOD FOR MANUFACTURING A NEEDLE-FREE ACCESS DEVICE", according to claim 15, characterized in that the cavity (212, 213) is angularly displaced from the cut in the surface of the first portion by 90 degrees.
    [0018]
    18. “ACCESS DEVICE WITHOUT NEEDLES”, characterized by having: an enclosure, having an interior cavity; and a folding valve (210), defined in any one of claims 1 to 9, disposed within the inner cavity.
    [0019]
    19. "NEEDLE-FREE ACCESS DEVICE" according to claim 18, characterized in that the septum (215) of the first portion is sealed in the housing to form a liquid space between the housing and the folding valve (210) and a space of separated air within the septum (215) of a first portion.
    [0020]
    20. "NEEDLE-FREE ACCESS DEVICE", according to claim 19, characterized in that the air space is ventilated by a passage through the enclosure to the external environment.
    [0021]
    21. “NEEDLE-FREE ACCESS DEVICE” according to claim 19, characterized in that a volume of the air space is reduced and a volume of the liquid space is enlarged, as the folding valve (210) moves from a sealed position to an open position.
    [0022]
    22. “NEEDLE-FREE ACCESS DEVICE” according to claim 18, characterized in that no cavity (212, 213) of the first portion is positioned below the cut (211) of the second portion.
    [0023]
    23. “NEEDLE-FREE ACCESS DEVICE” according to claim 18, characterized in that the second portion also has a flat surface that is positioned in line with an inlet opening in the housing, when the valve is in a sealed position, and is displaced from the inlet opening, when the valve is in an open position.
    [0024]
    24. “NEEDLE-FREE ACCESS DEVICE”, having: a lower housing, having an outlet; an upper housing sealed coupled to the lower housing to form an inner cavity, the upper housing having an inlet; and a folding valve (210), defined in any one of claims 1 to 9, disposed within the inner cavity; characterized in that the cylindrical wall of the first portion comprises a perimeter and two cavities (212, 213) on opposite sides of the cylindrical wall; and the cut (211) of the second portion is positioned at 90 degrees from the two cavities of the first portion; wherein the perimeter of the cylindrical wall is sealed in the lower casing, so as to form a liquid space between the valve and the coupled upper and lower casings and an air space within the septum (215) of the first portion, the air space being ventilated to the external environment through a passage in the inferior enclosure; and wherein the first portion folds before the second portion folds, as the access device is driven by a needle-free connector, so that the valve moves from a sealed position to an open position.
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    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US5555908A|1995-06-23|1996-09-17|Becton, Dickinson And Company|Valved PRN adapter for medical access devices|
    US5782816A|1995-09-07|1998-07-21|David R. Kipp|Bi-directional valve and method of using same|
    US5730418A|1996-09-30|1998-03-24|The Kipp Group|Minimum fluid displacement medical connector|
    US6706022B1|1999-07-27|2004-03-16|Alaris Medical Systems, Inc.|Needleless medical connector with expandable valve mechanism|
    EP1166818A1|2000-06-29|2002-01-02|Societe Des Produits Nestle S.A.|Medium cracking pressure valve|
    US6802490B2|2001-11-29|2004-10-12|Alaris Medical Systems, Inc.|Needle free medical connector with expanded valve mechanism and method of fluid flow control|
    US7244249B2|2002-05-08|2007-07-17|Cardinal Health 303, Inc.|Needle-free medical connector with expandable valve mechanism and method of fluid flow control|
    US7520489B2|2003-06-17|2009-04-21|Filtertek Inc.|Fluid handling device and method of making same|
    US6855138B2|2003-07-08|2005-02-15|Hsi-Chin Tsai|Injection joint for an intravenous device tube|
    US20050059952A1|2003-09-17|2005-03-17|Giuliano Amy S.|I.V. solution bag with a needleless port|
    DE10348016B4|2003-10-15|2007-05-03|Fresenius Kabi Deutschland Gmbh|Connector for medical fluid containing packaging and packaging for medical fluids|
    US20060025724A1|2004-07-27|2006-02-02|Globe Medical Tech, Inc.|Medical connector with valve|
    US7600530B2|2004-08-09|2009-10-13|Medegen, Inc.|Connector with check valve and method of use|
    EP1807148A2|2004-11-05|2007-07-18|ICU Medical, Inc.|Soft-grip medical connector|
    US8715247B2|2009-07-30|2014-05-06|Carefusion 303, Inc.|Collapsible valve|US6695817B1|2000-07-11|2004-02-24|Icu Medical, Inc.|Medical valve with positive flow characteristics|
    US7600530B2|2004-08-09|2009-10-13|Medegen, Inc.|Connector with check valve and method of use|
    US10478607B2|2004-08-09|2019-11-19|Carefusion 303, Inc.|Connector for transferring fluid and method of use|
    EP1807148A2|2004-11-05|2007-07-18|ICU Medical, Inc.|Soft-grip medical connector|
    US9168366B2|2008-12-19|2015-10-27|Icu Medical, Inc.|Medical connector with closeable luer connector|
    US8454579B2|2009-03-25|2013-06-04|Icu Medical, Inc.|Medical connector with automatic valves and volume regulator|
    US8715247B2|2009-07-30|2014-05-06|Carefusion 303, Inc.|Collapsible valve|
    US8323249B2|2009-08-14|2012-12-04|The Regents Of The University Of Michigan|Integrated vascular delivery system|
    US8636720B2|2009-11-16|2014-01-28|Carefusion 303, Inc.|Needleless access connectors and valve elements therefor|
    US8298196B1|2010-03-24|2012-10-30|Mansour George M|Needleless access connector and method of use|
    US8758306B2|2010-05-17|2014-06-24|Icu Medical, Inc.|Medical connectors and methods of use|
    WO2011146772A1|2010-05-19|2011-11-24|Tangent Medical Technologies Llc|Safety needle system operable with a medical device|
    WO2011146769A2|2010-05-19|2011-11-24|Tangent Medical Technologies Llc|Integrated vascular delivery system|
    TWI626063B|2011-06-03|2018-06-11|凱爾福郡３０３股份有限公司|Positive-displacement needleless access connector and method for manufacturing the same|
    US9067049B2|2011-07-25|2015-06-30|Carefusion 303, Inc.|Providing positive displacement upon disconnection using a connector with a dual diaphragm valve|
    EP3381505B1|2011-09-09|2020-05-27|ICU Medical, Inc.|Medical connectors with fluid-resistant mating interfaces|
    JP5241045B2|2011-09-12|2013-07-17|信越ポリマー株式会社|Connector valve body and connector|
    US8801678B2|2012-01-20|2014-08-12|Carefusion 303, Inc.|Piston for a needleless valve system|
    US9114244B2|2012-01-27|2015-08-25|Carefusion 303, Inc.|Needleless valve system fluid control|
    US9162029B2|2012-11-09|2015-10-20|Carefusion 303, Inc.|Tailless needleless valve system|
    JP6382210B2|2012-11-12|2018-08-29|アイシーユー・メディカル・インコーポレーテッド|Medical connector|
    CN103071200B|2013-01-29|2014-02-26|苏州林华医疗器械有限公司|Positive-pressure needle-free connecting piece|
    US9144672B2|2013-03-13|2015-09-29|Carefusion 303, Inc.|Needleless connector with compressible valve|
    US9370651B2|2013-03-13|2016-06-21|Carefusion 303, Inc.|Needleless connector with reduced trapped volume|
    US9278205B2|2013-03-13|2016-03-08|Carefusion 303, Inc.|Collapsible valve with internal dimples|
    US20140276459A1|2013-03-13|2014-09-18|Jonathan Yeh|Needleless connector with folding valve|
    US8708976B1|2013-03-14|2014-04-29|Carefusion 303, Inc.|Needleless connector with a tortuous fluid flow path|
    US9089682B2|2013-03-14|2015-07-28|Carefusion 303, Inc.|Needleless connector with support member|
    US8840577B1|2013-03-14|2014-09-23|Carefusion 303, Inc.|Needleless connector with flexible valve|
    AU2014238008B2|2013-03-15|2018-11-08|Icu Medical, Inc.|Medical connector|
    CN103272302B|2013-05-15|2019-05-14|浙江康泰医疗器械有限公司|Positive pressure connector|
    EP2862587A1|2013-10-15|2015-04-22|Becton Dickinson France|Tip cap assembly for closing an injection system|
    CA2932124A1|2013-12-11|2015-06-18|Icu Medical, Inc.|Check valve|
    CA2937744A1|2014-02-04|2015-08-13|Icu Medical, Inc.|Self-priming systems and methods|
    EP3124071A4|2014-03-26|2017-09-27|Terumo Kabushiki Kaisha|Connector and infusion set|
    CN106132474B|2014-03-28|2020-06-16|泰尔茂株式会社|Medical connector|
    JP2017526501A|2014-08-08|2017-09-14|ヴィヤイレ メディカル コンシューマブルズ エルエルシー|Cleaning port assembly for airway adapter|
    USD786427S1|2014-12-03|2017-05-09|Icu Medical, Inc.|Fluid manifold|
    USD793551S1|2014-12-03|2017-08-01|Icu Medical, Inc.|Fluid manifold|
    JP2019050777A|2017-09-15|2019-04-04|株式会社リコー|Complex and production method thereof, as well as cell adhesion substrate and production method thereof|
    WO2020198042A1|2019-03-22|2020-10-01|Puracath Medical, Inc.|Needleless connector valve for uv disinfection|
    法律状态:
    2017-10-03| B25B| Requested transfer of rights rejected|Owner name: CAREFUSION 303, INC (US) |
    2019-01-15| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2019-09-03| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
    2020-06-30| B07A| Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]|
    2020-12-01| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
    2021-01-19| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 19/01/2021, OBSERVADAS AS CONDICOES LEGAIS. |
    2021-06-22| B16C| Correction of notification of the grant|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/02/2010, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO |
    优先权:
    申请号 | 申请日 | 专利标题
    US12/512,719|2009-07-30|
    US12/512,719|US8715247B2|2009-07-30|2009-07-30|Collapsible valve|
    PCT/US2010/024875|WO2011014265A1|2009-07-30|2010-02-22|Collapsible valve|BR122019025490A| BR122019025490B8|2010-02-22|2010-02-22|foldable valve, needleless access device and method for manufacturing needleless access device|
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