![]() An apparatus and method for delivering media into the skin
专利摘要:
An apparatus and method for delivering media, in particular stem cells into the dermis layer of the skin, whereby a product containing the stem cells is applied to the skin, and then the skin is abraded through use of an abrasive hand piece and a compression source pushes air onto the skin. The abrasion pierces the skin barrier, allowing the compressed air to push the stem cells into the dermis layer of the skin and follicle providing an anti-aging treatment. 43 ----- ., 6 -~' 12yr -----32 F F, F F' F F 'F 'F 20 F F: F : F F: F - F - *~-22 Figi 公开号:AU2013204704A1 申请号:U2013204704 申请日:2013-04-12 公开日:2014-10-30 发明作者:Helen Greenberg;Ronald Allan Greenberg 申请人:Helen Greenberg; IPC主号:A61M35-00
专利说明:
1 An apparatus and method for delivering media into the skin FIELD OF THE INVENTION [0001] The present invention relates to a device and method for delivering stem cells into the dermis layer and follicle of the skin. BACKGROUND TO THE INVENTION [0002] Dermabrasion of the skin by the use of abrasive material is a known technique. Human skin is composed of three integrated layers, the epidermis, dermis, and subcutis. The bottom of the epidermis is where cell division generates new cells that travel up through the epidermis until they become the upper surface layers after some 3-4 weeks. The outermost layer of the epidermis is composed of several layers of dead skin which act as a buffer to the lower layers of skin. [0003] As a person ages the epidermis begins to degenerate becoming both thicker and drier. This can lead to blocked pores and other skin diseases. Skin damage from the sun and other sources also accumulates with age further affecting the appearance of the skin. As a result, various treatments including daily cleaning and facial scrubs are used to reduce the signs of aging and to ensure that the skin remains healthy and clean. [0004] A number of devices have been proposed to assist in removing dead skin cells from the epidermis including scraping blades and scrubbing pads. These devices dislodge the dead skin cells but do not remove them from the skin surface Consequently, unless the area is thoroughly cleaned the dead skin cells can remain on the skin surface and may result in blocked pores. Such devices are also only used in dermabrasion of the skin, i.e. the removal of dead skin cells from the epidermis and are not adapted for use for the purpose of moisturising the skin or otherwise treating below the epidermis or the base layers of the epidermis, the dermis or the hair follicle. [0005] It would be advantageous for a product to treat the base layer of the epidermis, the dermis and in particular the hair follicle. This is because this part of the skin contains stem cells produced by the body which supply the entirety of the follicle with new cells, and also assist in the healing of the epidermis if it is damaged. 2 Therefore, replacement of these stem cells or application of stems cells is known to assist in anti-aging. The use of embryonic stem cells can be prohibited or at least raises moral and ethical issues. Adult stem cells or synthetic stem cells can be used, and are used in various cosmetics, however the use of plant stem cells such as rose stem cells or apple stem cells is considered a viable alternative. This is because plant stem cells have similar properties and are of similar quality to human stem cells. [0006] Apple stem cells in are in particular believed to be effective. The use of apple stem cells in beauty treatments originated in Switzerland where a rare variety of apple tree-Uttwiler Spatlauber or Swiss Apple-is found and famed for its longevity. If unpicked bark or fruit is punctured, it heals, and apples remain on the trees without shrivelling or falling for far longer than other varieties. It was this singularity that prompted researchers to test the properties of the apples in relation to anti-aging benefits for skin. In one of the initial tests conducted by researchers, apple stem cells were tested against embryonic stem cells with results that were 79.9% better than those produced by the embryonic cells. [0007] Apple stem cells work in the same way as human stem cells; that is, they are self-renewing, regenerating damaged tissue, revitalising dying cells and replacing cells when others are past repair. Damaged cells lead to wrinkles and the appearance of age in skin (at its most basic, age is a reduction in the quantity and quality of work performed by these cells.) therefore the role of stern cells is crucial in the maintenance of a youthful appearance. The role of apple stem cells is basically the same: these cells protect, stimulate and repair, decreasing the signs of aging. The fluid found within the cells contains metabolites which ensure the longevity for which the Swiss Apple is famed. In addition, the use of this apple is considered a more ethical and legal option than that of embryonic stem cells in beauty products, and beauty companies have made significant use of the research that proves that these apples can reverse the aging process, increase the lifespan of human cells and even regrow lost hair. [0008] The market for stem cells in skin care exists largely for facial skin creams, and extensive testing has been conducted on such facial 'problems' as fine lines and crows' feet. Many anti-aging creams and lotions use the same ingredients, including retinol, which stimulates the turnover of cells and the production of collagen and elastin which are responsible for the maintenance of youthful skin. Alpha hydroxy acids work as gentle, non-manual exfoliants, breaking the bonds between dead cells and 3 hastening the 'shedding' process so that the younger, fresher skin beneath can emerge. Vitamins are often included: Vitamin C for brightening, Vitamin E for its antioxidants and Vitamin A, which plumps the skin. [0009] However, the most essential and crucial function of anti-aging cream is the temporary "plumping" effect as a result of a combination of ingredients such as retinol, Vitamin A and moisturiser. Few of these effects have been shown to be lasting in any form or to change the metabolism of skin. Research has also shown that many of these ingredients only prove any sort of change when they are inserted under the skin as opposed to being topically applied, and if inserted under the skin, they can no longer be classed as anti-aging creams but as a form of surgery, which is expensive [0010] There is no known device or method for impregnating the base epidermal layer or follicle, where the body's naturally occurring stem cells reside. It would be advantageous for the stem cells to be inserted for impregnated under the natural barrier of the skin to the base of the epidermis, the dermis and the hair follicle. SUMMARY OF THE INVENTION [0011] Therefore, according to one aspect, the present invention provides an apparatus for delivering media into the skin comprising a hand piece having an abrasive disk, and a source a source of compressed air adapted to be applied by the hand piece; wherein the application of the hand piece against the skin abrades the epidermal layer of the skin and the compressed air and any media present on the epidermis is caused to be injected into the dermis layer of the skin. [0012] In an embodiment, an apparatus for delivering media into the skin according to claim 1 wherein the rnedia is applied to the epidermis prior to the application of the hand piece. [0013] In an embodiment, an apparatus as in claim 2 wherein the media contains stem cells. [0014] In an embodiment, an apparatus for delivering media into the skin according to claim 3 wherein the stem cells are derived from plant materials and in particular from apples. 4 [0015] In an embodiment, an apparatus for delivering media into the skin according to claims 3 or 4 wherein the stem cells impregnate the follicle of the dermis. [0016] In an embodiment, a method for delivering media into the skin including the steps of: (a) applying a media containing stem cells to the epidermis of the skin, (b) rubbing a handpiece having an abrasive disc and a source of compressed air against the media on the skin, (c) wherein the disc abrades the epidermis and the compressed air pushes the media into the dermis of the skin. BRIEF DESCRIPTION OF THE DRAWINGS [0017] Preferred features, embodiments and variations of the invention may be discerned from the following Detailed Description which provides sufficient information for those skilled in the art to perform the invention. The Detailed Description is not to be regarded as limiting the scope of the preceding Summary of the Invention in any way. The Detailed Description will make reference to a number of drawings as follows. [0018] Figure 1 is a perspective view of a dermabrasion handpiece illustrating a first embodiment; [0019] Figure 2a is a side cross-sectional side view of the dermabrasion handpiece of Figure 1 illustrating a cap in a first position; [0020] Figure 2b is a side cross-sectional side view of the dermabrasion handpiece of Figure 1 illustrating a cap in a second position; [0021] Figure 3a is a side cross-sectional side view of a dermabrasion handpiece illustrating a second embodiment of the present invention in a first position; [0022] Figure 3b is a side cross-sectional side view of the dermabrasion handpiece of Figure 3a in a second position; and [0023] Figure 4 is a perspective view of a dermabrasion handpiece illustrating a third embodiment. DETAILED DESCRIPTION OF THE INVENTION [0024] The following detailed description of the invention refers to the accompanying drawings. Wherever possible, the same reference numbers will be used 5 throughout the drawings and the following description to refer to the same and like parts. Dimensions of certain parts shown in the drawings may have been modified and/or exaggerated for the purposes of clarity or illustration. [0025] The purpose of the invention is to impregnate the skin, and in particular the base epidermis, hair follicle and/or the dermis with a desired material or element, In preference, this material is stem cells in the form of plant stem cells and in particular apple stem cells. However it is to be understood that the invention can include any kind of stem cells, including adult or synthetic stern cells or any other active material which fills the dermis and skin follicle, such as peptides, Elements such as oxygen can also be impregnated into the skin according to the present invention. [0026] According to a preferred embodiment of the invention, the impregnation is performed through a hand tool assembly illustrated in Figure 1 which serves the dual purpose of abrading the skin and piercing the skin's natural barrier so that the stem cells can be inserted under the barrier and into the dermis and follicle. [0027] In an embodiment of the invention, the cream, lotion or serum containing the stem cells can be applied to the skin in the first stage of the treatment. In an embodiment of the invention, this is an available oxygen in liquid form mixed with stem cells and other high quality materials such as peptides. The dermabrasion of the skin and pressurisation of the skin using a hand tool 10 constitutes the second stage of the treatment, in which the skin is abraded to pierce the skin barrier and the stem cells are pushed under the pierced skin barrier to impregnate the follicle. Only a mild dermabrasion is used so that the follicle is vented rather than peeling the skin in a full dermabrasion. Essentially the process pierces or opens the skin lid and pushes the stem cells inside. [0028] Dermabrasion of the skin using such a hand tool is known, however in such apparatus the hand tool 10 containing an abrasive disc 12 is used in conjunction with a vacuum source. This includes multiple treatments done immediately after the other in which the skin is abraded with organic grains which do not pierce the skin but are wider and softer. Current methods include use of an abrasive disc 12 and a vacuum source which uses suction to draw the skin towards the hand piece 10. In the present invention, however, there is use of particles which will pierce the skin barrier, or use of an abrasive disc which will pierce the skin barrier, combined with a pressurised source which pushes on the skin. [0029] Therefore, the product applied to the skin prior to the application of the hand tool effectively penetrates the skin into the dermis and follicle, and also provides the benefit of the purified compressed air being pushed into the dermis and follicle. Therefore, the abrasion effectively separates the layers of the skin so that the oxygen and stem cells can impregnate the lower layers, producing a strong and lasting rejuvenation effect. [0030] For a detailed operation of a hand tool for dermabrasion the reader is referred to WO 99/23951 in the name of Ronald Allan Greenberg. Use of the hand tool 10 for the present invention is similar, however rather than use of a vacuum source, the present invention employs use of the pressurised source. In a first embodiment, as illustrated in Figure 1, the hand tool assembly 10 includes an abrasive disc 12, a handle 14 and a cap 16. The handle 14 includes an outlet passage 18 and an inlet passage 20. The outlet passage 18 is connected via tube 22 to a particle supply container (not shown) and the inlet passage 20 is connected via a tube 24 to a pressurised source (not shown). The disc 12 which contains an aperture or opening 26 is mounted on a head 28. The head 28 includes a threaded male member 30 and a longitudinally extending duct 32 which connects to the opening 26. It should be appreciated by the reader that there may be more than one opening 26 in the disc 12 providing all openings 26 connect with the duct 32, [0031] Furthermore, the abrasive disc 12 may include its own engagement surface 30 and be connected directly to the handle 14 without the need for a head 28. The head 28 may also include a recess 33 that can be engaged by a tool (not shown) which is used to connect and disconnect the head 28 from the handle 14. [0032] The handle 14 includes an engagement surface or threaded bore 34 that engages a threaded male member 30 enabling the disc 12 to be secured. In this way the abrasive disc 12 can be removably attached to the handle 14 by simply unscrewing. In the present example the engagement surfaces are in the form of threads 30 and 34, however, it should be appreciated that this is only one form of engagement means and another type could be used providing it securely locates the abrasive disc 12 onto the handle 14. The hand tool 10 is configured so that when the head 28 is attached to the handle 14, outlet passage 18 and duct 32 align. This means that during the operation of 7 the hand tool 10 particles are able to flow through the passage 18 into duct 32 and out through opening 26 of the abrasive disc 12. [0033] The present invention provides for different sizes of abrasive discs 12 which can be used for various applications, for instance, the smaller diameter abrasive discs can be used for localised areas such as around the eyes whilst the larger diameter discs can be used on flatter areas of skin. It should however be appreciated by the reader that all sizes of abrasive discs 12 and corresponding caps 16 can be attached to the same handle 14. This therefore provides a cost saving to the user as only one handle 14 has to be purchased. Furthermore, the handle 14 does not need to be completely detached from the pressurised and particle sources since only the abrasive disc 12 and corresponding cap 16 need to be replaced when a different diameter disc 12 is required. [0034] The cap 16 is constructed in the form of a hollow dome which includes a first opening 36 and a second opening 38. An engagement surface 40, as shown in Figure 2a and 2b, is located within the chamber of the dome 16 directly adjacent first opening 36. The engagement surface 40 corresponds to an engagement surface 42 on the handle 14. In this way the cap 16 can be removably attached to the handle 14. It should be appreciated that the engagement surface although illustrated in the form as threads is not limited to this particular configuration, The diameter of the second opening 38 is somewhat larger than the diameter of the abrasive disc 12. It is envisaged that the diameter of second opening 38 is around 2-5mm larger than the abrasive disc 12, however, it should be appreciated that the difference in the diameters is not limited to this particular size range. In this way the abrasive disc 12 can be located in a position where it protrudes through the second opening 38 beyond the surface of the cap 16, or alternatively, it can be located in a position where it is housed within the cap 16 and below the outer rim 43 of the second opening 38. [0035] Turning now to Figure 2a, the hand tool 10 is shown in first position where the abrasive disc 12 protrudes through the second opening 38. In this arrangement the abrasive disc 12 is applied directly onto the skin and moved to abrade the epidermis 44. It is also possible, but not essential, that the skin cells that are dislodged during this process are drawn up in the direction of arrow 46 through the inlet passage 20 by the vacuum that is produced by a vacuum source (not shown). Therefore, in an alternate 8 embodiment of the invention, there can be a dual vacuum and pressurised source, with the user switching between the two as required. [0036] The cap 16 is adjusted to a second position as illustrated in Figure 2b. In this position the abrasive disc 12 is contained within the chamber 50 of the cap 16 and does not protrude through the second opening 38. In this arrangement the skin 44 is partially drawn up and seals the chamber 50, and the vacuum produced by the dual vacuum and pressurised source (not shown) causes particles to flow from the particle source (not shown) through the passage 18, duct 32 and out through opening 26 of the abrasive disc 12. The particles act to abrade the skin surface 44 and are then drawn up through the inlet passage 20, In this way the skin 44 can be vigorously abraded with the abrasive disc 12 when the cap 16 is in the first position as illustrated in Figure 2a and then the skin 44 can be gently abraded with the use of particles when the cap 16 is in the second position as illustrated in Figure 2b. It should be appreciated by the reader that the abrasive disc 12 may be in contact with the skin 44 when the cap 16 is in the second position and thereby may also act to abrade the skin surface 44. [0037] In a further embodiment as illustrated in Figures 3a and 3b two different sized caps 16 can be used to adjust the position of the abrasive disc 12 in relation to opening 38, In Figure 3a the cap 16 is of a length that permits the abrasive disc 12 to protrude through the second opening 38 of the cap 16. In contrast, the cap 16 illustrated in Figure 3b is of a length that ensures that the abrasive disc 12 is contained within the chamber 50 of the cap 16 and does not protrude through opening 38. The caps 16 are frictionally held in place by sealing O-ring 52. [0038] As illustrated in Figures 2a, 2b, 3a and 3b, there are various sizes of abrasive discs 12. However, irrespective of the size of the abrasive disc 12 the distance between the edge of opening 38 and the edge of the disc 12 remains constant. This is accomplished by having caps 16 that correspond to particular sizes of abrasive disc 12. [0039] In yet a further embodiment as illustrated in Figure 4, the head 28 is connected to a shaft 54 which is slidably mounted within the handle 14. In this arrangement the location of the abrasive disc 12 in relation to the opening 38 can be adjusted during operation of the hand tool 10. This avoids the need to disengage the abrasive disc 12 and cap 16 from the handle. [0040] The hand tool 10 provides an assembly for abrading the outer layers of skin. The tool of the invention provides the ability to vigorously abrade the skin when the abrasive disc protrudes beyond and through the second opening of the cap. The abrasive disc can then be retracted or repositioned within the chamber enclosed by the cap and the tool can be used to draw off the dead skin particles or gently abrade the skin surface. The tool of the invention has the ability to adjust to the specific requirement of the user as the same handle allows the attachment of variously sized abrasive discs and caps to facilitate treatment. The use of a universal handle that can engage all the different sizes and configurations of abrasive discs reduces the cost of the apparatus and facilitates ease of use. [0041] It is to be understood that the above is for illustrative purposes of possible ways the invention can be achieved. However, the invention can be achieved through use of a simpler device which contains only a hand tool 10 and abrasive disc 12, with a pressurised source which pushes compressed air from the hand tool 10 and onto the skin. [0042] As a consequence of the physical abrasion of the skin, the natural barrier of the epidermis is pierced and the follicles open, allowing the insertion, impregnation or absorption of the stem cells. In preference, a cream or lotion containing the stem cells is applied to the epidermis 44 prior to the application of the hand tool. [0043] The pressurised air source is then used to impregnate the dermis and follicle with the stem cells. In preference, the vacuum source used during the dermabrasion is switched to a pressurised air source which expels air through the openings 26 and 38 and onto the skin. Because the air is pressurised and applied directly to the abraded epidermis 44, the stem cells are pushed or blown through the pierced skin barrier in the epidermis and down into the dermis and follicle. [0044] The dermis and follicle are then filled with plant stem cells, and because at a molecular level the body cannot tell the difference between a human stem cell and a plant stem cell, these plant stem cells work in the same way as the naturally occurring cells. The additional stem cells therefore encourage growth, repair and rejuvenation of the skin. The cells therefore 'feed' the skin and improve the quality of the skin, which 10 appears healthier and younger. [0045] In an embodiment of the invention, the cream, lotion or serum containing the stem cells can be applied to the skin in the first stage of the treatment. The dermabrasion of the skin and pressurisation of the skin using the hand tool 10 constitutes the second stage of the treatment, in which the skin is abraded at the same time as the stem cells are pushed under the pierced skin barrier to impregnate the follicle. Only a mild dermabrasion is used so that the follicle is vented rather than peeling the skin in a full dermabrasion. Essentially the process pierces or opens the skin lid and pushes the stem cells inside. [0046] It must be noted that the dermis is the layer in which wrinkles form and which determines the structural integrity and elasticity of the skin-both of which are associated with the signs of aging and to which treatment must be applied if it is to have any true and lasting effect on the skin's appearance. Therefore, without penetration of this layer, no cream or lotion will have any significant effect. [0047] This is an improvement of the use of stem cells externally applied to the epidermis by creams and lotions; as such products only influence the epidermis, being the first layer of skin. Lotions and creams, in and of themselves, cannot penetrate the deeper layers of the skin including the dermis which contains the follicles. It is particularly advantageous for the stern cells or other media to reach the dermis, as the dermris is the layer of skin in which wrinkles form and which determines the structural integrity and elasticity of the skin. This is associated with the signs of aging and therefore only once the media is applied to the dermis can it have any true and lasting effect on the skin's appearance. [0048] Therefore application of stem cells via creams, lotions or serums to the epidermis cells would not penetrate down to the dermis and follicle and would only constitute a superficial treatment. Through the impregnation of the dermis and follicle, the plant stem cells actively engage with the stem cells naturally produced by the body and mimic their purpose and effect to rejuvenate skin. Therefore the present invention provides a longer lasting and more effective treatment. It is possible to surgically inject the stem cells directly into the skin; however such an injection would not have the same effect as it would penetrate too deeply into the skin beyond the dermis and folicle, which is where the stem cells are naturally produced. 11 [0049] In an alternate embodiment of the invention, the impregnation of the dermis and follicle is conducted after a full dermabrasion is applied to the skin using known methods, In this embodiment, as the dead cells have already been removed by the dermabrasion, the stem cells are applied directly to the treated epidermis 44 and then the hand tool 10 with the pressurised source is applied to the skin to impregnate the dermis. [0050] In an embodiment of the invention, three treatments are applied to the skin, The first treatment abrades the skin and pierces the epidermis barrier in order to get the stem cells under the barrier and into the dermis and follicle. This first treatment is followed by a rest period. The second and third treatments also consist of abrasion of the skin and impregnation of the stem cells, however in these treatments the pressure is increased to get more stem cells deeper into the dermis and follicle. [0051] In an embodiment of the invention, the hand tool 10 and pressurised source can also be used to impregnate the skin with oxygen. A liquid product, in preference a bio available oxygen mixed with stem cells, is applied to the skin. The hand tool using the compression source is the applied to the skin [0052] In an alternate embodiment, a dermabrasion treatment is first applied to the desired area using the suction. This microdermabrasion draws the blood to the surface of the skin and pierces the epidermis barrier, but not enough so that the blood is drawn from the skin, but that it rests just below the surface, The vacuum is then switched to air pressure, which pushes air into the skin through the pierced barrier. The blood is therefore infused with additional oxygen and the pressurised air from the hand tool 10 pushes the infused blood back, enriching the cellular matrix with oxygen. [0053] Whilst an initial dermabrasion of the skin is an advantage to the treatment it is not necessary for the treatment to be effective. The application of the product containing stem cells to the skin and the use of the hand tool with the compression source, without an initial dermabrasion treatment using the vacuum source, still ensures that the skin barrier is pierced and the stem cells are pushed into the dermis and follicle. Therefore, it is an embodiment of the invention that the apparatus can be used by an unskilled user, for example in a home unit which requires no prior dermabrasion and no vacuum source. The physical abrasion of the disc 12 combined with the compressed or purified air will push the product (applied superficially to the skin) into 12 the dermis and follicle, with a pressure control regulating compression. [0054] The reader will now appreciate the present invention which uses a hand tool to abrade and pierce the epidermis and push pressurised air into the skin in order to impregnate the dermis and follicle with stem cells. [0055] Further advantages and improvements may very well be made to the present invention without deviating from its scope. Although the invention has been shown and described in what is conceived to be the most practical and preferred embodiment, it is recognised that departures may be made therefrom within the scope and spirit of the invention, which is not to be limited to the details disclosed herein but is to be accorded the full scope of the claims so as to embrace any and all equivalent devices and apparatus. Any discussion of the prior art throughout the specification should in no way be considered as an admission that such prior art is widely known or forms part of the common general knowledge in this field. [0056] In the present specification and claims (if any), the word 'comprising' is equivalent to the word "including" and its derivatives including 'comprises' and 'comprise' include each of the stated integers but does not exclude the inclusion of one or more further integers.
权利要求:
Claims (6) [1] 1. An apparatus for delivering media into the skin comprising: a hand piece having an abrasive disc; and a source of compressed air adapted to be applied by the hand piece; wherein the application of the hand piece against the skin abrades the epidermal layer of the skin and the compressed air and any media present on the epidermis is caused to be injected into the dermis layer of the skin. [2] 2. An apparatus for delivering media into the skin according to claim 1 wherein the media is applied to the epidermis prior to the application of the hand piece. [3] 3. An apparatus as in claim 2 wherein the media contains stem cells. [4] 4. An apparatus for delivering media into the skin according to claim 3 wherein the stem cells are derived from plant materials and in particular from apples. [5] 5. An apparatus for delivering media into the skin according to claims 3 or 4 wherein the stem cells impregnate the follicle of the dermis. [6] 6. A method for delivering media into the skin including the steps of: (a) applying a media containing stem cells to the epidermis of the skin (b) rubbing a handpiece having an abrasive disc and a source of compressed air against the media on the skin (c) wherein the disc abrades the epidermis and the compressed air pushes the media into the dermis of the skin.
类似技术:
公开号 | 公开日 | 专利标题 US11224728B2|2022-01-18|Devices and methods for treating the skin using a porous member US20210154453A1|2021-05-27|Devices and methods for treating the skin US20150182447A1|2015-07-02|Method for improving skin condition comprising six steps and system therefor US20150140114A1|2015-05-21|Skin treatment protocol utilizing amniotic solution AU2013204704B2|2014-11-20|An apparatus and method for delivering media into the skin EP3501592A1|2019-06-26|Non-invasive delivery method CN108096138A|2018-06-01|A kind of anti-aging skin repairs liquid and preparation method thereof JP2018534337A|2018-11-22|Compositions containing natural extracts and their use on skin and hair KR20100108891A|2010-10-08|A vessel with head massage portion and hair tonic storage KR20170130742A|2017-11-29|Cosmetic Composition For Regenerating skin TW201517931A|2015-05-16|A method for extracting substance from starfish US8286639B2|2012-10-16|Method for non-surgical facial rejuvenation KR20100039597A|2010-04-16|Instrument for inducing neocollagenesis in skin treatments Konda et al.2013|Age reversing modalities: An overview CN109718195A|2019-05-07|A kind of facial mask liquid containing stem cell factor TWM621229U|2021-12-11|Structure filled with seaweed needle carrier CN107970151A|2018-05-01|A kind of eye skin nursing frost CN110868972A|2020-03-06|Silicone pad with active ingredients for skin care and anti-aging CN107822935A|2018-03-23|A kind of Essence of the extract containing epidermal stem cells KR20210095247A|2021-08-02|Skin type custom scrub instant manufacturing method KR20130034158A|2013-04-05|Neck band Jacono2012|Face of the Future: Look Natural Not Plastic: a Less-invasive Approach to Enhance Your Beauty and Reverse Facial Aging CN107823119A|2018-03-23|A kind of pore refining skin care item containing sealwort stem cell extract CN107789315A|2018-03-13|A kind of anti-aging skin care product containing sealwort stem cell extract Aswin et al.2021|GANDHAKA AND KUSHTA
同族专利:
公开号 | 公开日 AU2013204704B2|2014-11-20|
引用文献:
公开号 | 申请日 | 公开日 | 申请人 | 专利标题 US6004286A|1996-03-19|1999-12-21|Powderject Research Limited|Particle delivery| US6500183B1|1999-11-12|2002-12-31|Altair Instruments, Inc|Microdermabrasion device| US6511486B2|2001-03-09|2003-01-28|Silhouet-Tone Ltee|Dermabrasion hand tool for abrasively removing skin surface| WO2005065032A2|2004-01-08|2005-07-21|Tavtech Ltd.|A high velocity liquid-gas mist tissue abrasion device| WO2006002489A1|2004-07-07|2006-01-12|Ronald Allan Greenberg|An assembly for use in dermabrasion having an abrasive disc| US20080171495A1|2005-03-07|2008-07-17|Martine Diat|Micro-Sanding Machine With A Sanding Effect By Air Disc-Abrasive| US20110130706A1|2009-11-19|2011-06-02|Follica, Inc.|Sequential body surface treatment|
法律状态:
2015-03-19| FGA| Letters patent sealed or granted (standard patent)| 2020-11-05| MK14| Patent ceased section 143(a) (annual fees not paid) or expired|
优先权:
[返回顶部]
申请号 | 申请日 | 专利标题 AU2013204704A|AU2013204704B2|2013-04-12|2013-04-12|An apparatus and method for delivering media into the skin|AU2013204704A| AU2013204704B2|2013-04-12|2013-04-12|An apparatus and method for delivering media into the skin| 相关专利
Sulfonates, polymers, resist compositions and patterning process
Washing machine
Washing machine
Device for fixture finishing and tension adjusting of membrane
Structure for Equipping Band in a Plane Cathode Ray Tube
Process for preparation of 7 alpha-carboxyl 9, 11-epoxy steroids and intermediates useful therein an
国家/地区
|