澳大利亚专利AU2012358926A1 Positive airway pressure system with head position control

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[0089] The invention is directed to a positive airway pressure (PAP) system with a head mounted harness assembly with a housing and a head position sensor located within or secured to the housing that detects the position of a patient's head, and communicates this head position information to a controller of the system which may be disposed within the housing having the position sensor or a second housing. The controller varies the output pressure of the pressure source, e.g. a rotary compressor, based, at least in part, on the head position information provided by the head position sensor. In a preferred embodiment, the position sensor is an accelerometer. HANCP-00301
公开号:AU2012358926A1
申请号:U2012358926
申请日:2012-03-09
公开日:2013-09-26
发明作者:Nathaniel L. Bowditch；Tarmigan Casebolt；Thomas G. Goff
申请人:Hancock Medical Inc；
IPC主号:A61M16-06

专利说明:
POSITIVE AIRWAY PRESSURE SYSTEM WITH HEAD POSITION CONTROL FIELD OF THE INVENTION [0001] The invention is generally directed to a system and method for controlling the treatment a patient receives and particularly to controlling a Positive Airway Pressure (PAP) device. BACKGROUND OF THE INVENTION [0002] During sleep, all muscles, including those of the upper airway, lose tone and relax. Obstructive Sleep Apnea (OSA) occurs when tissue blocks the upper airway during sleep. This will cause a drop in blood oxygen and a rise in blood carbon dioxide. The brain will sense these changes, and awaken the person enough to restore muscle tone to the structures of the upper airway, and the airway will reopen. [0003] The severity of OSA is determined by the number of blockages per hour of sleep, also called the apnea-hypopnea index (AHI). These include complete blockages (apneas) and partial blockages (hypopneas). The severity of OSA, as determined by a sleep study, is classified as follows: SEVERITY BLOCKAGES PER HOUR Mild 5-15 Moderate 15-30 Severe 30+ [0004] OSA disrupts restorative sleep. Chronic fatigue has long been recognized as the hallmark of OSA. But more recently, large clinical studies have shown a strong link 1 Atty. Docket No. HANCP-00320 between OSA and stroke and death. This link is independent of other risk factors for cardiovascular disease such as hypertension, obesity, high cholesterol, smoking and diabetes. [0005] As discussed above, several structures can cause blockage of the upper airway: the tongue, the soft palate, the uvula, the lateral walls of the pharynx, the tonsils and the epiglottis. In most patients, the blockage is caused by a combination of these anatomical structures. [0006] Many current procedures and devices have been used to stabilize, modify or remove tissue in the airway to treat OSA. In uvulopalatopharygoplasty (UPPP), the uvula, part of the soft palate and the tonsils are removed. A Repose stitch is used to tie the tongue to the mandible to prevent its posterior movement. Oral appliances move the mandible forward (very slightly) to create more space in the airway. [0007] None of these approaches has achieved much more than a 50% success rate, with success defined as a 50% decrease in AHI to a score below 20. The limited success of these approaches likely stems from the fact that they don't address all anatomical sources of a blockage. [0008] The most widely used therapeutic system for OSA is a PAP system such as a continuous positive airway pressure (CPAP) system. A CPAP system usually consists of three parts: a mask forming a largely airtight seal over the nose or nose and mouth, an air pressurizing housing or console and an elongated tube connecting the two. The mask contains one or more holes, usually at the junction with the tube. A CPAP system works by pressurizing the upper airway throughout the breathing cycle, essentially 2 HANCP-00301 inflating the airway to keep it open. A CPAP system thus maintains a pneumatic splint throughout the respiratory cycle. [0009] Unlike interventions that treat specific blockages, a CPAP system addresses all potential blockage sites. The success rate in patients (dropping AHI by >50%) exceeds 80%, and its cure rate (decreasing AHI below 5) is close to 50%. The drawback to a CPAP system is poor patient compliance, i.e. continuous use by the patient. In one large study, only 46% of patients were compliant with a CPAP system, even though compliance was defined as using the CPAP system at least 4 hours per night at least 5 nights per week. [0010] Critical pressure is the airway pressure a given patient requires to maintain an open airway during sleep. Critical pressure is measured in cm of water, and will typically be between 6 and 14 cm of water for a patient requiring CPAP. In a given patient, the efficacy of a CPAP system goes up as pressure is increased. But, as higher pressure makes the CPAP system more uncomfortable to the patient, patient compliance drops. The goal of the healthcare professional in setting up a CPAP system for a patient is to achieve critical pressure without exceeding it. This will make the CPAP system both effective and tolerable. [0011] In a given patient, there are several factors which affect critical pressure. The pressure supplied by the CPAP system necessary to achieve critical pressure varies through the breathing cycle. When a patient is exhaling, the patient is supplying some air pressure to the airway, and thus requires limited pressure from the CPAP system to maintain critical pressure. But when the patient is inhaling, he is decreasing pressure in the airway. During inhalation, more pressure is required by the CPAP system to 3 HANCP-00301 maintain critical pressure in the airway. There are now many available CPAP systems that monitor the respiratory cycle, and provide less pressure during the portions of the respiratory cycle when less external pressure is required to maintain critical pressure in the airway. Such adaptive systems, which include systems commercially known as BiPAP and C-Flex, make CPAP systems more comfortable, improving the compliance of many patients. So, during the respiratory cycle, critical pressure does not change. But the pressure contributed by the CPAP system to maintain critical pressure changes during the respiratory cycle. [0012] Critical pressure can change based on sleeping position in many patients. Critical pressure will usually be higher when a patient is in a supine position (i.e. on his back) than when a patient is in a lateral position (on his side). This is because many of the structures that can block the airway, such as the tongue and uvula, are anterior to the airway. When a patient is in a supine position, gravity pulls these structures toward the airway, and a greater pressure (critical pressure) is required to keep the airway open. When a patient is in a lateral position, gravity is not pulling these structures directly into the airway, and thus less pressure is required to maintain an open airway. This was demonstrated in a study published in 2001 (Penzel T. et al. 2001. Effect of Sleep Position and Sleep Stage on the Collapsibility of the Upper Airways in Patients with Sleep Apnea; SLEEP 24(1): 90-95.). Additionally, most sleep studies used to diagnose OSA will track body position and will determine whether a patient has airway blockages more frequently when sleeping in a supine position. Other sleep studies have found that the lateral position results in fewer observed apneas than the supine position. (Cartwright R. et al. 1984 Effect of Sleep Position on Sleep Apnea Severity: 4 HANCP-00301 SLEEP 7:110-114). (Pevernagie D. et al. 1992 Relations Between Sleep Stage, Posture, and Effective Nasal CPAP Levels in OSA: SLEEP 15: 162-167). Further studies have shown that aphea events in the supine position tend to be more sever, have longer duration, be accompanied by a greater oxygen desaturation and increased heart rate, and be more likely to result in arousals and awakenings. (Oksenberg A. et al. 2000 Association of Body Position with Severity of Apneic Events in Patients with Severe Non-positional Obstructive Sleep Apnea: CHEST 118: 1018-1024) SUMMARY OF THE INVENTION [0013] This invention is directed to a positive airway pressure (PAP) system and method for treating of a patient with OSA or other breathing problems wherein the system has a head position sensor that is mounted onto the top of the patient's head and a pressure source that has an output pressure controlled by a head position signal from the head position sensor. The PAP system includes at least one housing having an interior configured to receive a system component and being configured to be secured to the top of the patient's head, preferably in a median position. One system component is a gas pressure source, such as a compressor, with a controllable output pressure which is disposed within the interior of the housing and preferably has a controllable motor drive. The gas pressure source has an outlet opening which is configured to be connected to a tubular member that preferably leads to a mask which is configured to sealingly fit over the patient's nose and/or mouth. The PAP system has a harness assembly which is configured to secure at least part of the system to the top a the patient's head. 5 HANCP-00301 [0014] A PAP system embodying features of the invention has a head position sensor, such as an accelerometer, that is secured within or to a system housing or on or to the harness assembly that is configured to secure at least part of the PAP system to the user's head. The head position sensor is configured to sense the position of the patient's head with respect to a reference plane (e.g. a horizontal plane) and to generate a signal representing the sensed position of the patient's head. A suitable accelerometer is a Freescale 3-Axis MEMS Accelerometer (MMA845XQ), particularly the MMA8453Q model, which generates a signal series representing a three axis orientation with respect to gravity. [0015] Another system component is a controller, preferably a microprocessor such as Atmel AVR Model # ATMMega328, that is provided to control the PAP system so as to adjust the output of the gas pressure source according to the sensed position of the patient's head to provide a critical pressure to the patient's airway passage to maintain patency. The controller is preferably secured within the system's housing and is configured to receive the head position signals transmitted from the head position sensor. The controller is configured to receive the head position signals and to determine a suitable pressure source output pressure for the particular sensed head position from the received head position signal. The controller preferably has a stored relationship between sensed head position and suitable pressure source output pressure and is configured to generate a control signal for the pressure source representing the determined suitable gas pressure. The control signal generated by the controller is transmitted to the pressure source, e.g. the driving motor of a compressor, 6 HANcP-00301 to control the output of the pressure source so as to provide the determined suitable gas pressure for the sensed position of the patient's head. [0016] In one embodiment, a pressure sensor senses the actual gas pressure directed to or received by the user and the controller compares the directed or received sensed pressure with the desired or determined suitable pressure and adjusts the control signal to the pressure source so as to provide the pressure source output that provides the critical pressure that maintains patency in the patient's airway passage. [0017] Alternatively, the pressure source may be operated at a constant pressure level and a control valve disposed between the pressure source and the patient's mask receives the control signal to control the output pressure. The control valve may be provided in the compressor outlet, in a gas flow line to the patient's mask or in the patient's mask, to provide the determined suitable gas pressure to the patient that maintains patency in the patient's airway passage. [0018] Although the accelerometer and the controller are described herein as two separate devices, they may be combined into a single device. [0019] The controller is configured to determine suitable compressor output pressures from the head position signal-pressure source output pressure relationship for at least two patient head positions, one head position may be a supine position and another second patient position might be a lateral position, preferably at least 200 from the supine position. In one embodiment, the controller may be provided with a readable library listing a plurality of head position signals with corresponding suitable pressure source output pressures. In another embodiment, the controller has a preprogrammed algorithm representing a relationship between head position signal and corresponding 7 HANCP-00301 suitable pressure source output pressure. The microprocessor is configured to use the received head position signals to calculate from the algorithm suitable pressure source output pressures and generate suitable control signals for the pressure source. The relationship between the head position signal and suitable pressure source output pressure may be a stepped function, e.g. two or more positions with suitable pressure source output pressure or a continuous function. There may be a gradual change in pressure between stepped functions. The continuous function preferably has a greater rate of change in the pressure source output pressure with respect to head position with head positions between about 300 and 600 from the supine position (0Q). [0020] The set point for a suitable pressure source output pressure for one of the head positions, e.g. the supine position, may be set by a health professional based upon the patient's sleep study. The set point for other position may also be set by the health professional. [0021] In one embodiment, the supine position may be defined as within 300 of vertical, with vertical being the sleeping position where the nose is pointed directly upward, orthogonal to the sleeping plane which is horizontal. [0022] The pressure source is preferably a rotary blower such as the Nidec Copal TF037C, which has a turbine and a controllable drive motor. An alternative pressure source may be a bellows system which maintains a pressurized storage tank that provides pressurized breathing gas to the patient's mask. Other gas pressure sources may be utilized. [0023] The electrical power source for the pressure source drive motor is preferably a portable power source component such as one or more batteries which may be 8 HANCP-00301 provided within the system housing. However, the electrical power source may be an electrical power cord for connection to an electrical source (e.g. a wall outlet or a separate battery pack) and may be provided to directly supply electrical power to the pressure source and/or to recharge one or more batteries. The electrical power source is connected to and powers the drive motor that controls the output pressure of the pressure source such as a rotary compressor. [0024] In one embodiment, the system housing may be one or more separate housings, and is mounted on top of a patient's head, preferably in a medial position, by a one or more straps of the harness assembly that are secured to the housing. Other means to secure the system housing to the patient's head may be used. [0025] Initially, a health professional may set the output pressure of the compressor for one or more of the patient's head positions that have been based upon a sleep study performed on the patient. The second head position should be at least 200 away from the first head position. Optionally, the health professional may also set the set point for the output pressure of the system when the patient's head is at other positions. Preferably, the controller is programmed to select a suitable compressor output pressure from a preset table or library for at least one head position or determine a suitable pressure from a preprogrammed algorithm that is based upon the sensed position of the patient's head. The algorithm defines the relationship between the head position signal and the suitable compressor output pressure. [0026] With the PAP system mounted on the patient's head, the head position sensor is first calibrated, preferably when the patient's head is in a supine position. The calibrated head position sensor senses the patient's head position and generates a 9 HANCP-00301 sensed head position signal which is transmitted to the controller. The controller determines a suitable pressure source output pressure for the sensed head position signal and generates a control signal for the pressure source to provide the suitable pressure output pressure. In one embodiment, the controller compares the determined suitable pressure source output pressure with the current pressure output of the pressure source and if they differ by a specified amount, the controller generates a new control signal for the pressure source. If they do not differ by the specified amount the system loops back and continues to monitor the patient's head position. [0027] The pressure source output pressure requirements can vary between a low point at exhalation to a high point at inhalation for each position of the patient's head which forms an output pressure envelope for the patient. [0028] During sleep, the position of the patient's head can be the most important determinant of critical pressure for the patient since the anatomical structures that might block the airway (such as the tongue, the soft palate, the uvula and the tonsils) are in the head. Thus, the position sensor that determines the position of the head can be valuable in effectively controlling the pressure output of a PAP system. [0029] In one embodiment the PAP system provides a first (higher) gas pressure from the compressor when the patient's head is in a supine position and a second (lower) pressure when the patient's head is in a lateral position. The gas pressure supplied to the patient when the patient's head is in a lateral position would likely be 1-8 cm of water less than the pressure supplied when the patient's head is in the supine position. Additionally, the PAP system can vary pressure more continuously based on several patient sleeping positions. With such a system, higher pressure would be supplied to 10 HANCP-00301 the patient by the pressure source the closer a person's head is to a completely supine position with the patient's nose lying in a vertical plane. Slightly lower pressure could be supplied, for example, if a person's head was 200 off from the supine position and other positions further away from the supine position. The lowest gas pressure would usually be when the patient's head is in a lateral position 90* or more from the supine position. [0030] The patient's head positions are described herein primarily in terms of the supine position, a lateral position and positions between these two positions about a longitudinal axis passing through the patient's head. The head position sensor may also sense when the patient's head is tilted toward or away from the patient's chest, or rotated further than a lateral position 900 away from the supine position. A patient whose head is tilted far forward during sleep (i.e. the chin is close to the chest), may experience an even higher frequency of airway blockages than when in a supine position and may need a higher gas pressure to maintain an open airway passage than when in a supine position. [0031] The PAP system which modulates its output pressure based on a patient's head position while sleeping; could also be used to determine whether a given patient's sleep apnea event frequency and severity are affected by sleeping position, and PAP system output could be modulated accordingly. For example, the PAP system pressure may be lowered from about 11 cm (of water) to about 9 cm as the patient moved from a supine to a lateral sleeping position. The system could also further modulate pressure output based upon whether the number of airway blockages increased or decreased (e.g. as measured by pressure sensors in the PAP mask or within the gaseous flow from the compressor to the PAP mask) and the corresponding patient position. 11 HANCP-00301 [0032] The controller of the PAP system may be used to provide different pressure source output pressures within the pressure envelope at different points in the respiratory cycle at any given patient head positions. For example, higher pressure source output pressures may be provided during inhalation and lower pressure source output pressures during exhalation to maintain the critical pressure within the patient's airway passage. [0033] The features of this invention would allow a PAP system to provide different suitable gas pressures depending on the head position of the patient. This would improve patient comfort while providing the critical pressure at different positions to maintain an open airway. Additionally, since patients prefer lower PAP pressures, such a system might also cause patients to prefer to sleep in positions (such as a lateral position) that cause the system to provide a lower gas pressure to the patient. The lower output pressure would also spur the patient to sleep in a position that leads to fewer airway blockages. The lower output pressure would tend to disturb a person's sleep much less because of comfort of lower pressure and less noise due to the slower operation of the compressor drive motor. [0034] A wearable PAP system embodying features of the invention preferably has one or more housings which insulate the patient's head from heat, sound and vibration from the from the PAP system. For example a pad may be positioned at the bottom of the housing(s) or the bottom of the housing may be spaced from the patient's head to minimize such heat, noise and vibrations. The drive motor for the compressor may have additional vibration and noise dampers to produce a less disturbing operation. Materials such as foams, gels, plastic members, rubber-like members or contained 12 HANcP-00301 fluids may be used to isolate and/or reduce the noise and vibrations which emanate from the pressure source. [0035] Further, a PAP system embodying features of the invention may be spaced from the top of the patient head and be supported by pod extensions or feet which are secured to the harness assembly. The bottoms of the pod extensions or feet are preferably padded to minimize patient discomfort. Because a substantial portion of the bottom surface of the housing is spaced away from the patient's head, trapped heat underneath the bottom of the housing is minimized. The open space between the patient's head and the bottom of the housing(s), in addition to providing ventilation also reduces noise and vibration from the system housing to the patient. [0036] Moreover, because a self-contained PAP system embodying features of the present invention does not have a gas delivery tube connecting the patient's face mask to a remote pressure generating unit, there are fewer restrictions on a patient's movement during sleep. There is little or no likelihood of pulling the mask away from its operative position on the patient's face, and there is no remote pressure generating unit which might be pulled off an adjacent night stand. [0037] These and other advantages of the invention will become more apparent from the following detailed description of embodiments of the invention when taken in conjunction with the accompanying exemplary drawings. BRIEF DESCRIPTION OF THE DRAWINGS [0038] Figure 1 shows a perspective view of a PAP system embodying features of the invention. 13 HANCP-00301 [0039] Figure 2 is a perspective view of a PAP system shown in Figure 1 with a mask mounted over the patient's nose and the housing mounted on the patient's head. [0040] Figure 3 is a rear view of the PAP system shown in Figure 2. [0041] Figure 4 is a side elevational view of the system shown in Figure 1 with portions of the system housing removed to illustrate the various components within the system housing. [0042] Figure 5 is a top view of the system with portions of the system housing removed to illustrate the various components within the system housing. [0043] Figure 6 is a block diagram illustrating the system shown in Figure 1. [0044] Figure 7 is a flow diagram illustrating position calibration of the system processing. [0045] Figure 8 is a flow diagram illustrating processing for a PAP system embodying features of the invention. [0046] Figure 9 is a flow diagram illustrating system processing using scalar measurement. [0047] Figure 10 is a top view of the PAP system shown in Figure 2 with the patient's head in the supine position and the patient's nose pointed directly up, orthogonal to the sleeping plane. [0048] Figure 11 is a top view of the PAP system with the patient's head less than 200 from the supine position . [0049] Figure 12 is a top view of the PAP system with the patient's head about 30* 600 from the supine position. 14 HANCP-00301 [0050] Figure 13 is a top view of the PAP system with the patient's head in the lateral position 90* from the supine position. [0051] Figure 14 is a top view of the PAP system with the patient's torso in a lateral position and the patient's head in a position position greater than 600 and less than 90* from the supine position. [0052] Figure 15 is a top view of the PAP system with the patient's torso in a lateral position and the patient's head in a position greater than 90* from the supine position. [0053] Figure 16 shows a side view of a user with the head tilted down, bringing the chin closer to the user's chest. [0054] Figure 17 shows a side view of a user with the head tilted up, moving the chin further away from the user's chest. [0055] Figure 18 illustrates how different algorithms can relate head position input signals (i.e. representing degrees from a supine position) and suitable pressure source output pressures. [0056] Figure 19 is a graph schematically illustrating output pressure variations within a pressure envelope for a supine and a lateral head positions. [0057] Figure 20 is an exploded perspective view of a housing for a PAP system showing how the components are fit into the interior of the housing. [0058] Figure 21 illustrates how the housing shown in Figure 19 interfaces with a replaceable strap structure or harness assembly for securing the PAP system to the head of a patient or user. The shaded contact interface securely attaches the PAP system to the strap structure. 15 HANCP-00301 [0059] Figure 22 is a perspective view which depicts a PAP system which has multiple housings to contain the various components of the system. [0060] Figure 23 is a perspective view showing a PAP system with multiple housings that are interconnected by a fabric or mesh that is integral with the harness assembly. [0061] Figure 24 is a perspective view that illustrates a PAP system having multiple housings interconnected by hinged, semi-rigid elements. DETAILED DESCRIPTION OF EMBODIMENTS OF THE INVENTION [0062] Figures 1-3 are perspective views of a PAP system 10 embodying features of the invention. As shown, the system 10 basically includes a system housing 11 and a harness assembly 12 secured to the bottom of the housing. The harness assembly 12 has a plurality of straps 13 and 14 and cross strap 15 to secure the housing 11 to a patient's head 16 as shown in Figure 2. The free ends of straps 13 and 14 have push in type connectors 17 and 18, as shown in Figure 1, for securing the free ends to mask 20 as shown in Figure 2. The straps 13-15 hold the mask 20, as shown in Figure 2, in a sealed engagement with the patient's nose 21. [0063] As best shown in Figures 4 and 5, the interior 22 of system housing 11 contains a compressor 23, a controller 24, a position sensor 25 and batteries 26 and 27 to supply electrical power to the compressor 23. A gas delivery tube 28 is secured to the discharge 29 of the compressor 23 and extends to the mask 20 for the delivery of a breathable gas to the patient's nose 21 as shown in Figure 2. A system activation/calibration button 30 may be provided on the front of the housing 11. An electrical power chord 31 (shown in phantom) may be provided for powering the compressor 23 directly from a separate electrical source such as an electrical outlet or 16 HANCP-00301 battery pack (not shown) or for recharging one or more of batteries 26 and 27. A vibration and sound deadening layer 32 may be provided on the bottom 33 of the system housing 11 and between the compressor 23 and supporting structure (not shown) therefore. [0064] Figure 6 is a block diagram of the system 10 illustrating the interconnection of the various components of the system. A position signal 34 from the head position sensor 25 is transmitted to the controller 24 which in turn generates a control signal 35 for the compressor 23 based upon the received head position signal 34. The controller 24 may have an input module 36 that allows for the manual input of compressor output pressure set point(s) that provides one or more suitable compressor output pressures for the compressor for one or more received head position signals 34. The gas delivery tube 28 which delivers pressurized gas from the compressor 23 to the mask 20 may have a pressure sensor 37 which generates a pressure signal 38 that is fed back to the controller 24 to ensure that the desired gas pressure for the sensed patient position is delivered to the patient. The pressure sensor 37 may be alternatively located in the patient's mask 20 or the compressor discharge 29. [0065] Figure 7 is a flow diagram illustrating the calibration of the head position sensor 25. With the PAP system 10 mounted onto the patient's head, the patient reclines into a calibration position, such as the supine position, and pushes the activation button 30 on the front of the housing 11. The preferred head position for calibrating the sensor 25 is the supine position with the patient's nose is orthogonal to the sleeping plane 40. The system takes a measurement from the head position sensor 25, an accelerometer, and compares this measurement to the Gravitational constant 17 HANCP-00301 (G). Once the measurement is within 10% of G, the value is recorded to a nonvolatile memory in the controller 24. The system 10 may be calibrated by the patient or by a health professional. [0066] Figure 8 is a flow diagram illustrating an operation of the calibrated PAP system 10 embodying features of the invention. The calibrated head position sensor 25 senses the patient's head position and generates a head position signal 34 representing then sensed head position. This signal 34 is transmitted (by a wire or wirelessly) to controller 24, compares the received head position signal 34 with a stored relationship between head position signal and compressor output pressure and determines a suitable compressor output pressure for the sensed head position. The controller 24 compares this determined pressure output to the current pressure source output pressure, and, if the determined pressure output differs from the current pressure output by more than a specified amount, then the controller will generate a new control signal for the pressure source or compressor. This new control signal will control the pressure source to deliver a suitable output pressure that is delivered to the patient or user through a mask 20 so as to maintain a critical pressure within the patient's airway passage. If the determined pressure output does not differ from the current pressure output of the pressure source by more than a specified amount, the control signal will not be changed. The system 10 will continue to sense the head position of the patient and restart the loop. [0067] In another embodiment, the input module 36 may be used by a health professional to input a set-point for a suitable compressor output pressure for the calibrated sensor head position that has been determined by the patient's sleep test. 18 HANcP-00301 The controller 24 may continuously or periodically compare the sensed head position signal 34 from the position sensor 25 with the calibrated head position signal. If the comparison indicates that the patient's sensed head position deviates from the calibrated head position less than a certain amount, e.g. 200, then the system will loop (providing the same control signal 34 to the compressor to provide a suitable compressor output pressure) until the controller detects a head position signal which represents a sensed head position that deviates more than the certain amount. When the controller 24 determines that the sensed head position deviates more that the certain amount, such as the lateral position, the controller compares the head position signal 34 with a stored relationship between head position signal and suitable compressor output pressure to determine the suitable compressor output pressure for the new sensed head position such as the lateral head position where the patient's nose lies in a plane 41 parallel to the sleeping plane 40 when the patient's head 16 is resting on pillow 42. The controller 24 then generates a new control signal 35 for the compressor to enable the compressor to provide the suitable output pressure for the sensed new lateral head position. The system 10 will loop providing the same output pressure until a new head position signal 34 indicates that the patient's head is in a new position which is more than 200 away from the lateral position. [0068] A flow chart is shown in Figure 9 illustrating a way to scale the pressure calculation as the head is moved from the calibrated position. The position sensor 25, an accelerometer, takes a measurement which is compared with gravity to determine if the accelerometer is stabilized. If the measurement is within 10% of G, the vector measurement of the accelerometer is converted to a scalar measurement by performing 19 HANCP-00301 a Dot product, using the vector in the direction of the calibration position gravity. Next, a minimum pressure is added to the scalar reading and then a pressure envelop is created to control the output pressure of the pressure source. [0069] Figure 10 shows the top view of a patient wearing a PAP system 10 embodying features of the invention while lying in the supine position with the head 16 and nose pointed directly up, orthogonal to the sleeping plane 40. This is the preferred calibration position. A patient sleeping in the supine position will generally require a pressure that is higher than what is required in more lateral sleeping positions. [0070] Figure 11 shows a top view of a patient wearing a PAP system 10 embodying features of the invention while lying with his or her torso in the supine position and the head 16 rotated slightly laterally, In this figure, angle theta represents the deviation of the head from a true supine position, here shown to be less than 200. [0071] Figure 12 shows the top view of a patient wearing a PAP system 10 embodying features of the invention while lying with the patient's torso in the supine position and the patient's head 16 rotated more laterally. In this Figure, angle theta represents the deviation of the head from a true supine position, here shown to be between 300 and 600. [0072] Figure 13 shows a top view of a patient wearing a PAP system 10 embodying features of the invention while lying with the patient's torso in the lateral position and the head 16 of the patient in a neutral lateral position on pillow 42 with the nose pointed in a plane 41 parallel to the sleeping plane 40. [0073] Figure 14 shows a top view of a patient wearing a PAP system 10 embodying features of the invention while lying with the torso in the lateral position and the head 16 20 HANCP-00301 rotated toward the supine direction relative to the lateral sleeping position which is parallel to the sleeping plane 40. Angle alpha represents the rotation of the patient's head from true supine position, here shown to be less than 900. [0074] Figure 15 shows the top view of a patient wearing a PAP system 10 embodying features of the invention while lying with the patient's torso in a lateral position and the patient's head 16 rotated beyond 90* from the supine position [0075] Figure 16 shows a side view of a patient wearing a PAP system 10 embodying features of the invention while lying with the patient's torso and head 16 in the supine position with the head tilted forward such that the patient's chin is closer to the patient's chest. [0076] Figure 17 shows a side view of a patient wearing a PAP system 10 embodying features of the invention while lying with the patient's torso and head 16 in the supine position with the head tilted backward such that the patient's chin is further from the patient's chest. [0077] The controller may be programmed to provide a suitable compressor output pressure for positions such as when the patient's head is rotated more than 900 from the supine position as shown in Figure 15 and for position such as when the patient's head is tilted forward or backward as shown in Figures 16 and 17. The stored relationship between the sensed head position signal 34 and suitable compressor output pressure may be a list of sensed head position signals with corresponding suitable compressor output pressures in a readable library in the controller 24. Alternatively, the stored relationship may be an algorithm which defines a curve of head position verses compressor output pressure. 21 HANCP-00301 [0078] The relationship between the sensed position of the patient's head and the pressure output of the pressure source can take several forms, as depicted in the graph shown in Figure 18. Line A depicts a step function in which, at some point between supine position and a position 90* from the supine position, the pressure output drops. Such a step function could also have multiple steps between the supine position and 90* from the supine position, as depicted in line B. [0079] Alternatively, the relationship between head position and output pressure may follow an inclined straight line, as depicted by line C. Another possibility is shown in line D which depicts a relationship in which there is a continuous pressure drop moving from a supine position to 900 from supine, but the rate of pressure drop is greatest between 300 and 600 from the supine position. Yet another relationship is shown in line E wherein there is an inclined linear portion between the supine pressure and lateral pressure between 300 and 600. [0080] While not shown, the pressure could continue to drop at positions greater than 900 from the supine position. Additionally, the relationship between pressure and sensed head position may have a more elaborate, advanced curve shape to provide more appropriate pressures at each position. Other relationships may be employed. [0081] Figure 19 graphically illustrates a respiratory cycle through two different head positions, supine and lateral. In the supine position, the delivered pressure is higher and the respiratory cycle causes the pressure to fluctuate within a range about the clinical target pressure between inhalation and exhalation. In the lateral position, the delivered pressure is lower and fluctuates between inhalation and exhalation similar to the fluctuations in the supine position. 22 HANCP-00301 [0082] An alternative PAP system 50 embodying features of the invention is shown in Figure 20 in an exploded view. In this embodiment, the compressor 51, controller 52, position sensor 53 and battery 54 are secured to the top inner lining of the housing 55. The lower margins of housing 55 are secured to the shaded areas 56 of base 57 which is secured to the replaceable harness assembly 58 as shown in Figure 21. In this manner the housing 55 along with the secured components 51-54 could be reusable, whereas the harness assembly 57 and 58 which has direct contact with the patient can be easily replaced as needed. The shaded contact areas 56 of the base 57 may be recessed so as to provide a better fit for the lower margins of the housing 55. [0083] Another alternative embodiment is shown in Figure 22 wherein a PAP system 60 embodying features of the invention has multiple housings, housing 61 which holds the compressor and housing 62 which holds the controller and battery. Housings 61 and 62 are secured to the harness assembly 63 which holds the system 60 against the patient's head. The position sensor is secured to the interior of one of the housings, preferably to the controller that is secured to the housing 62. With this particular configuration of the PAP system 60, the weight of the PAP system can be more evenly distributed over the top of the patient's head. Moreover, a smaller area of the patient's head is covered with the housing which improves the comfort and heat regulation and reduces potential irritation of the patient's scalp. Additionally, the harness assembly 63 may have a flexible base 64 and the multiple housings 61 and 62 secured to the flexible base can better conform to the shape of the patient's head and facilitate easier replacement of the various components of the system. Other advantages are apparent. 23 HANCP-00301 [0084] Figure 23 illustrates yet another alternative PAP system 70 having multiple housings which contain system components. In PAP system 70, housing 71 contains the pressure source and motor drive (not shown) and housing 72 contains the controller (not shown). The electrical power source is a plurality of battery cells 73 which are secured to the harness assembly 74, preferably to a flexible base 75 which is part of the harness assembly. The harness assembly 74 secures the multiple housings 71 and 72 and battery cells 73 to the patient's head. Conductor wire(s) (not shown) interconnect the battery cells 73 and the motor drive for the compressor and the controller and the motor drive for the compressor. [0085] Figure 24 illustrates yet another alternative PAP system 80 having multiple housings which contain system components. In PAP system 80, housing 81 contains the pressure source and motor drive (not shown) and housing 82 contains the controller (not shown). Housing 83 contains the electrical power source such as one or more batteries (not shown). The plurality of housings 81-83 are secured to a harness assembly 85. The individual housings 81-83 are interconnected by flexible connections or joints 86 and 87. The harness assembly 85 secures the multiple housings 81, 82 and 83 to the patient's head. Conductor wire(s) (not shown) interconnect the electrical power source and the motor drive for the compressor and conductor wires (not shown) connect the the controller and the motor drive for the pressure source. [0086] While particular forms of the invention have been illustrated and described herein, it will be apparent that various modifications and improvements can be made to the invention. For example, while the description herein has focused on PAP systems, the system may be utilized in a variety of breathing systems. Additionally, the PAP 24 HANCP-00301 systems are primarily described herein as self-contained breathing systems. However, many of the advantageous features described herein may be applicable to breathing systems with remote control and/or pressure sources and wherein the head position sensor is secured to the top of the patient's head. To the extent not otherwise described herein, materials and structure may be of conventional design. [0087] Moreover, individual features of embodiments of the invention may be shown in some drawings and not in others, but those skilled in the art will recognize that individual features of one embodiment of the invention can be combined with any or all the features of another embodiment. Accordingly, it is not intended that the invention be limited to the specific embodiments illustrated. [0088] Terms such as "element", "member", "component", "device", "means", "portion", "section", "steps" and words of similar import when used herein shall not be construed as invoking the provisions of 35 U.S.C §112(6) unless the following claims expressly use the terms "means for" or "step for" followed by a particular function without reference to a specific structure or a specific action. All patents, patent applications and publications referred to above are hereby incorporated by reference in their entirety. 25 HANcP-00301

权利要求:
Claims (20)
[1] 1. A positive airway pressure system, comprising: a. a housing having an interior configured to receive one or more components of the positive airway pressure system; b, a pressure source component which has a controllable drive motor and which is configured to provide breathable gas to a patient's airway passage; c. a head position sensor which is configured to be mounted to the top of a patient's head, which is configured to sense the position of the patient's head and which emits a head position signal representing the sensed position of the patient's head; and d. a controller component which is configured to receive the head position signal from the position sensor, which is configured to determine a suitable pressure source output pressure for a sensed position of the patient's head and which is configured to generate a control signal representing the suitable pressure source output pressure in response to the sensed head position signal and which is configured to send the generated control signal to the controllable motor drive of the pressure source to control the output pressure of the pressure source in response thereto to provide the suitable pressure output pressure for the sensed head position. 26 HANCP-00301
[2] 2. The positive airway pressure system of claim 1 including a harness assembly having at least one strap configured to secure the housing to the patient's head.
[3] 3. The positive airway pressure system of claim 2 wherein the position sensor is secured within or to the housing.
[4] 4. The positive airway pressure system of claim 1 wherein the controller component is configured to determine suitable pressure source output pressures for at least two sensed positions of the patient's head
[5] 5. The positive airway pressure system of claim 4 wherein the pressure source component is secured within the housing.
[6] 6. The positive airway pressure system of claim 4 wherein the controller component is configured to allow the suitable pressure source component output pressure for one of the at least two positions of the patient's head to be set by a health professional.
[7] 7. The positive airway pressure system of claim 4 wherein the controller component has an algorithm representing a relationship between suitable pressure source component output pressures with respect to corresponding head position signals that includes the at least two suitable pressure source output pressures and the controller component is configured to determine from the algorithm a suitable pressure source component output pressure corresponding to the sensed head position signal.
[8] 8. The positive airway pressure system of claim 7 wherein the algorithm defines a curve in which the rate of change of pressure source component output pressure is greater for head positions between 30* and 600 from a supine position. 27 HANCP-00301
[9] 9. The positive airway pressure system of claim 7 wherein the algorithm defines a stepped curve.
[10] 10. The positive airway pressure system of claim 1 including a mask configured to sealingly engage the patient's nose or mouth or both and to receive the pressure source output.
[11] 11. The positive airway pressure system of claim 10 including a delivery tube connecting the mask to a discharge outlet of the pressure source component.
[12] 12. The positive airway pressure system of claim 1 wherein the controller component is configured to generate a control signal for the first suitable pressure source component output pressure when the position sensor senses that the patient's head is in a supine position.
[13] 13. The positive airway pressure system of claim 4 wherein a first suitable pressure source component output pressure is greater than a second suitable pressure source component output pressure.
[14] 14. The positive airway pressure system of claim 1 wherein the pressure source component is a rotary compressor.
[15] 15. The positive airway pressure system of claim 1 including an electrical power source component for the pressure source component motor drive.
[16] 16. The positive airway pressure system of claim 15 wherein the electrical power source component is a battery.
[17] 17. The positive airway pressure system of claim 15 wherein the electrical power source component includes a power cord configured to be connected to an electrical outlet or a separate battery pack. 28 HANCP-00301
[18] 18. The positive airway pressure system of claim 17 wherein the power cord is configured to recharge one or more batteries.
[19] 19. The positive airway pressure system of claim 1 in which the head position sensor is an accelerometer.
[20] 20. The positive airway pressure system of claim 1 including at least two housings which contain system components. 29 HANCP-00301

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公开号 | 公开日

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US20120199124A1|2012-08-09|

US20140076319A1|2014-03-20|

US20120199125A1|2012-08-09|

US20130056004A1|2013-03-07|

AU2012358926B2|2016-08-04|

US8336546B2|2012-12-25|

US20150096565A1|2015-04-09|

US9180267B2|2015-11-10|

引用文献:

公开号 | 申请日 | 公开日 | 申请人 | 专利标题

US3649964A|1970-06-04|1972-03-21|Willy A E Schoelz|Ventilated welders face mask|

US3721233A|1970-10-30|1973-03-20|W Montgomery|T-shaped tracheal stent|

US3736927A|1971-05-17|1973-06-05|F Misaqi|Self-contained air purifier and conditioner unit|

US3822698A|1973-01-22|1974-07-09|R Guy|Powered air-purifying respirator helmet|

US3881198A|1973-08-13|1975-05-06|William A Waters|Detachable air conditioning unit for headwear|

US3998213A|1975-04-08|1976-12-21|Bio-Volt Corporation|Self-adjustable holder for automatically positioning electroencephalographic electrodes|

US4019508A|1976-05-21|1977-04-26|Research Development Systems, Inc.|Wearable, self-contained fully mobile personal breathing apparatus for surgeons and operating room personnel|

US4233972A|1978-05-08|1980-11-18|Wolfgang Hauff|Portable air filtering and breathing assist device|

DE2964203D1|1978-07-12|1983-01-13|Jackson Richard R|Nested hollow fiber humidifier|

US4297999A|1979-07-19|1981-11-03|Kitrell John V|Portable resuscitation apparatus|

JPH0352290B2|1981-04-24|1991-08-09|Somedo Pty Ltd||

US4430995A|1981-05-29|1984-02-14|Hilton Joseph R|Power assisted air-purifying respirators|

GB2118442A|1982-04-15|1983-11-02|James Gordon Whitwam|Improvements in or relating to respirators|

NO842275L|1983-06-07|1984-12-10|Racal Safety Ltd|RESPIRATOR.|

US4549542A|1983-07-25|1985-10-29|Chien Chao Huei|Multiple-effect respirator|

US4765316A|1987-04-20|1988-08-23|Marshall Walter D|Scalp stimulator|

US4836219A|1987-07-08|1989-06-06|President & Fellows Of Harvard College|Electronic sleep monitor headgear|

US4782832A|1987-07-30|1988-11-08|Puritan-Bennett Corporation|Nasal puff with adjustable sealing means|

US4802485A|1987-09-02|1989-02-07|Sentel Technologies, Inc.|Sleep apnea monitor|

US5065756A|1987-12-22|1991-11-19|New York University|Method and apparatus for the treatment of obstructive sleep apnea|

US4829998A|1988-02-25|1989-05-16|Jackson Richard R|Delivering breathable gas|

GB8815179D0|1988-06-25|1988-08-03|Racal Safety Ltd|Differential pressure sensor|

US5046492A|1988-07-15|1991-09-10|Stackhouse Wyman H|Clean room helmet system|

US5113853A|1988-11-07|1992-05-19|Dickey Jonathan B|Helmet with filtered air supply|

DE4017336C1|1990-05-30|1991-06-13|Draegerwerk Ag, 2400 Luebeck, De||

US5054480A|1990-06-14|1991-10-08|Bio Medical Devices, Inc.|Personal air filtration and control system|

NZ238544A|1990-06-18|1994-10-26|Ponnet Gilman En Anthony|Respirator with hygroscopic material adjacent outlet to patient|

US5054484A|1990-11-21|1991-10-08|Hebeler Jr Robert F|Tracheostomy device|

US5104430A|1991-06-11|1992-04-14|Her Mou Lin|Mask with an air filtering device|

FR2680467B1|1991-08-21|1997-04-04|Intertechnique Sa|RESPIRATORY PROTECTION EQUIPMENT AGAINST POLLUTANTS.|

DE4133235C2|1991-10-07|1993-09-23|Draegerwerk Ag, 23558 Luebeck, De||

WO1993009834A1|1991-11-14|1993-05-27|University Technologies International Inc.|Auto cpap system|

US5372130A|1992-02-26|1994-12-13|Djs&T Limited Partnership|Face mask assembly and method having a fan and replaceable filter|

US5533500A|1992-03-04|1996-07-09|Her-Mou; Lin|Helmet with an air filtering device|

US5490502A|1992-05-07|1996-02-13|New York University|Method and apparatus for optimizing the continuous positive airway pressure for treating obstructive sleep apnea|

US5353788A|1992-09-21|1994-10-11|Miles Laughton E|Cardio-respiratory control and monitoring system for determining CPAP pressure for apnea treatment|

US5349946A|1992-10-07|1994-09-27|Mccomb R Carter|Microprocessor controlled flow regulated molecular humidifier|

GB9307733D0|1993-04-14|1993-06-02|Msa Britain Ltd|Respiratory protective device|

IL105930A|1993-06-07|1997-03-18|Natan Oren|Therapeutic respiration device|

US5937855A|1995-04-21|1999-08-17|Respironics, Inc.|Flow regulating valve in a breathing gas delivery system|

US5394870A|1993-09-03|1995-03-07|Minnesota Mining And Manufacturing Company|Respirator blower unit housing with pommel-like strap support member comprising lower exterior support surface|

US5517986A|1993-09-28|1996-05-21|Respironics, Inc.|Two-point/four-point adjustable headgear for gas delivery mask|

US5671733A|1994-04-21|1997-09-30|Snap Laboratories, L.L.C.|Method of analyzing sleep disorders|

US6932084B2|1994-06-03|2005-08-23|Ric Investments, Inc.|Method and apparatus for providing positive airway pressure to a patient|

US5485851A|1994-09-21|1996-01-23|Medtronic, Inc.|Method and apparatus for arousal detection|

US5461934A|1994-12-20|1995-10-31|Budd; Alexander G.|Ambient air collection device for use with a self-contained breathing apparatus|

GB9503012D0|1995-02-16|1995-04-05|Smiths Industries Plc|Humidifier systems|

US5564124A|1995-04-20|1996-10-15|Bio-Medical Devices, Inc|Personal body ventilation system|

US5657752A|1996-03-28|1997-08-19|Airways Associates|Nasal positive airway pressure mask and method|

US6513526B2|1996-07-26|2003-02-04|Resmed Limited|Full-face mask and mask cushion therefor|

US6561191B1|1997-02-10|2003-05-13|Resmed Limited|Mask and a vent assembly therefor|

US5928189A|1997-04-22|1999-07-27|Phillips; Robert E.|Activity responsive therapeutic delivery system|

IL132748A|1997-05-07|2003-11-23|Compumedics Sleep Pty Ltd|Apparatus and method for controlling gas or drug delivery to a patient|

FR2766377B1|1997-07-22|1999-09-17|Giat Ind Sa|OVERPRESSURE VENTILATION DEVICE FOR GAS MASK|

US6135106A|1997-08-22|2000-10-24|Nellcor Puritan-Bennett, Inc.|CPAP pressure and flow transducer|

WO1999013931A1|1997-09-18|1999-03-25|Caradyne Limited|Portable respirator|

US20030062045A1|1998-09-18|2003-04-03|Respironics, Inc.|Medical ventilator|

US5954050A|1997-10-20|1999-09-21|Christopher; Kent L.|System for monitoring and treating sleep disorders using a transtracheal catheter|

SE9703913D0|1997-10-27|1997-10-27|Astra Ab|Face mask|

DE69940502D1|1998-01-16|2009-04-16|Depuy Orthopaedics Inc|DEVICE FOR COVERING THE HEAD|

AT456388T|1998-11-06|2010-02-15|Caradyne R & D Ltd|PORTABLE VENTILATOR|

US8701664B2|1998-11-06|2014-04-22|Caradyne Limited|Apparatus and method for relieving dyspnoea|

US6122773A|1999-04-15|2000-09-26|Katz; Marc|Ventilated hardhat|

US6435180B1|1999-07-01|2002-08-20|J&M Distributors Limited|Method and apparatus for delivering humidified air to a face mask|

US6615831B1|1999-07-02|2003-09-09|Respironics, Inc.|Pressure support system and method and a pressure control valve for use in such system and method|

WO2001010489A2|1999-08-05|2001-02-15|MAP Medizintechnik für Arzt und Patient GmbH & Co. KG|Device for supplying a respiratory gas, humidifying device, respiratory gas tube, and connecting device therefor|

US6179586B1|1999-09-15|2001-01-30|Honeywell International Inc.|Dual diaphragm, single chamber mesopump|

SE9904382D0|1999-12-02|1999-12-02|Siemens Elema Ab|High Frequency Oscillation Patient Fan System|

US7204250B1|1999-12-16|2007-04-17|Compumedics Limited|Bio-mask|

GB9929745D0|1999-12-17|2000-02-09|Secr Defence|Determining the efficiency of respirators and protective clothing and other improvements|

WO2001052675A2|2000-01-18|2001-07-26|Stryker Instruments|Air filtration system including a helmet assembly|

US6553992B1|2000-03-03|2003-04-29|Resmed Ltd.|Adjustment of ventilator pressure-time profile to balance comfort and effectiveness|

US6371112B1|2000-05-22|2002-04-16|Noam Bibi|Device, system and method for preventing collapse of the upper airway|

US20020104541A1|2000-05-22|2002-08-08|Dr. Haim Bibi Medical Services Ltd.|Devices, systems and methods for preventing collapse of the upper airway and sensors for use therein|

US6772762B2|2000-05-24|2004-08-10|Gregory Hubert Piesinger|Personal powered air filtration, sterilization, and conditioning system|

US6986352B2|2000-06-22|2006-01-17|Resmed Limited|Mask with gusset|

DE10031079A1|2000-06-30|2002-02-07|Map Gmbh|Measuring patient breathing and state, correlates present respiration signals with prior reference measurements, to adjust CPAP therapy pressure accordingly|

US6349724B1|2000-07-05|2002-02-26|Compumedics Sleep Pty. Ltd.|Dual-pressure blower for positive air pressure device|

US6532960B1|2000-07-10|2003-03-18|Respironics, Inc.|Automatic rise time adjustment for bi-level pressure support system|

US6435184B1|2000-09-01|2002-08-20|Tien Lu Ho|Gas mask structure|

AU9320301A|2000-09-28|2002-04-08|Invacare Corp|Carbon dioxide-based bi-level cpap control|

SE0003531D0|2000-10-02|2000-10-02|Breas Medical Ab|Auto CPAP|

US20020078958A1|2000-12-21|2002-06-27|Sensormedics Corporation|Infant CPAP system with airway pressure control|

WO2002065901A2|2000-12-29|2002-08-29|Ares Medical, Inc.|Sleep apnea risk evaluation|

DE10103810A1|2001-01-29|2002-08-01|Map Gmbh|Device for supplying a breathing gas|

JP2004530474A|2001-04-24|2004-10-07|メディ−フィジックス・インコーポレイテッド|Method and apparatus for humidifying hyperpolarized noble gases and related humidified pharmaceutical grade inhalable hyperpolarized gas products|

SE0103182D0|2001-09-25|2001-09-25|Siemens Elema Ab|Procedure for lung mechanical examination and respiratory system|

JP4264619B2|2001-10-12|2009-05-20|山本光学株式会社|Respiratory protection|

US6679265B2|2001-10-25|2004-01-20|Worldwide Medical Technologies|Nasal cannula|

US6752146B1|2001-12-10|2004-06-22|Boris Altshuler|Civilian anti-terrorist attack gas mask|

JP2003210585A|2002-01-21|2003-07-29|Hiroaki Nomori|Tracheotomic tube|

US20070240716A1|2002-02-15|2007-10-18|Marx Alvin J|Personal air filtering and isolation device|

US6634864B1|2002-02-19|2003-10-21|Vapore, Inc.|High fluid flow and pressure in a capillary pump for vaporization of liquid|

DE10210878B4|2002-03-12|2018-01-04|Drägerwerk AG & Co. KGaA|Apparatus for breathing support|

US6881192B1|2002-06-12|2005-04-19|Pacesetter, Inc.|Measurement of sleep apnea duration and evaluation of response therapies using duration metrics|

US7471280B2|2002-06-19|2008-12-30|Koninklijke Philips Electronics N.V.|Tactile device|

WO2004007010A1|2002-07-12|2004-01-22|Fisher & Paykel Healthcare Limited|Breathing assistance apparatus|

WO2005007056A2|2003-07-22|2005-01-27|Zinder, Oren|A respiratory aid system and method|

US7089941B2|2002-08-20|2006-08-15|Bordewick Steven S|Face mask support|

US7845353B2|2002-08-20|2010-12-07|Aeiomed, Inc.|Face mask support|

CA2496154A1|2002-08-20|2004-03-04|Aeiomed, Inc.|Face mask support|

US7069932B2|2002-09-06|2006-07-04|Ric Investments, Llc.|Patient interface with forehead support system|

US20040226562A1|2002-12-06|2004-11-18|Bordewick Steven S.|Blower assembly for CPAP|

DE10307580B3|2003-02-22|2004-06-03|Rheinmetall Defence Electronics Gmbh|Magnetic field sensor position detection and tracking method for controlling image simulation for pilot night-vision device|

AU2003901042A0|2003-03-07|2003-03-20|Resmed Limited|Back-up rate for a ventilator|

AT413364B|2003-03-10|2006-02-15|Schuh Rainer Karl|Clamping frame for a plane|

AU2004224345B2|2003-03-21|2010-02-18|Welch Allyn, Inc.|Personal status physiologic monitor system and architecture and related monitoring methods|

FR2853838A1|2003-04-18|2004-10-22|Taema|Nasal respiratory assembly for treatment of sleep apnea, has nasal respiratory mask associated to turbine that comprising soundproof cowling and vaned-rotor arranged in cowling|

US7717112B2|2003-06-04|2010-05-18|Jianguo Sun|Positive airway pressure therapy management module|

US7588033B2|2003-06-18|2009-09-15|Breathe Technologies, Inc.|Methods, systems and devices for improving ventilation in a lung area|

AU2003903138A0|2003-06-20|2003-07-03|Resmed Limited|Method and apparatus for improving the comfort of cpap|

FR2856930B1|2003-07-04|2007-09-07|Saime Sarl|MODULAR TURBINE BREATHING AIDING DEVICE.|

US6990691B2|2003-07-18|2006-01-31|Depuy Products, Inc.|Head gear apparatus|

DE10332899B3|2003-07-19|2004-09-30|Dräger Safety AG & Co. KGaA|Respiratory equipment comprises an inner wall running along a visor to form an air channel, an air-conveying device connected to the air channel, gas outlet openings in the inner wall, and an air outlet opening|

US7191781B2|2003-08-05|2007-03-20|Innomed Technologies, Inc.|Nasal ventilation interface and system|

DE10337138A1|2003-08-11|2005-03-17|Freitag, Lutz, Dr.|Method and arrangement for the respiratory assistance of a patient as well as tracheal prosthesis and catheter|

US20050131288A1|2003-08-15|2005-06-16|Turner Christopher T.|Flexible, patient-worn, integrated, self-contained sensor systems for the acquisition and monitoring of physiologic data|

US7357136B2|2003-08-18|2008-04-15|Ric Investments, Llc|Patient interface assembly and system using same|

US7664546B2|2003-09-18|2010-02-16|Cardiac Pacemakers, Inc.|Posture detection system and method|

NZ546389A|2003-09-25|2009-09-25|Resmed Ltd|Ventilator mask and system|

US6961186B2|2003-09-26|2005-11-01|Takumi Technology Corp.|Contact printing using a magnified mask image|

US20070113854A1|2003-12-12|2007-05-24|Resmed Limited|Injection control for non-invented mask|

US7178525B2|2004-02-06|2007-02-20|Ric Investments, Llc|Patient interface assembly supported under the mandible|

US7118608B2|2004-04-12|2006-10-10|Lovell William S|Self-powered, wearable personal air purifier|

US7575005B2|2004-05-18|2009-08-18|Excel-Tech Ltd.|Mask assembly with integrated sensors|

US20070208269A1|2004-05-18|2007-09-06|Mumford John R|Mask assembly, system and method for determining the occurrence of respiratory events using frontal electrode array|

DE102005039346A1|2004-08-20|2006-02-23|Resmed Ltd., North Ryde|Breathable gas humidifying method for patient, involves channeling breathable gas along air flow path that includes access to a portion of moisture to increase humidification of breathable gas|

US7887492B1|2004-09-28|2011-02-15|Impact Sports Technologies, Inc.|Monitoring device, method and system|

US7814911B2|2004-10-15|2010-10-19|Aeiomed, Inc.|Nares seal|

US20060096596A1|2004-11-05|2006-05-11|Occhialini James M|Wearable system for positive airway pressure therapy|

CN101166555B|2004-12-08|2010-05-12|温吐斯医学公司|Respiratory devices and methods of use|

US7195014B2|2005-03-22|2007-03-27|Hoffman Laboratories, Llc|Portable continuous positive airway pressure system|

US20060231097A1|2005-04-02|2006-10-19|Dougherty Timothy R|Apparatus for CPAP therapy|

WO2006123691A1|2005-05-18|2006-11-23|Matsushita Electric Works, Ltd.|Sleep diagnostic system|

US20070000493A1|2005-06-01|2007-01-04|Cox Kingsley J|Apparatus for maintaining airway patency|

JP5356808B2|2005-06-14|2013-12-04|レスメド・リミテッド|Method and apparatus for controlling mask leakage in CPAP treatment|

WO2007012140A1|2005-07-29|2007-02-01|Resmed Limited|Method and apparatus for managing moisture buildup in pressurised breathing systems|

US8316848B2|2005-08-15|2012-11-27|Resmed Limited|CPAP systems|

US7499739B2|2005-10-27|2009-03-03|Smiths Medical Pm, Inc.|Single use pulse oximeter|

US8172766B1|2005-11-04|2012-05-08|Cleveland Medical Devices Inc.|Integrated sleep diagnosis and treatment device and method|

US7942824B1|2005-11-04|2011-05-17|Cleveland Medical Devices Inc.|Integrated sleep diagnostic and therapeutic system and method|

US7471290B2|2005-11-18|2008-12-30|Cardiac Pacemakers, Inc.|Posture detection system|

US8371293B2|2005-12-16|2013-02-12|Resmed Limited|Bladder cushion, forehead cushion, headgear straps, headgear cap and/or chinstrap|

WO2007117716A2|2006-04-10|2007-10-18|Aeiomed, Inc.|Apparatus and methods for administration of positive airway pressure therapies|

US7516743B2|2006-04-20|2009-04-14|Viasys Sleep Systems, Llc|Continuous positive airway pressure device and configuration for employing same|

US8427020B2|2006-04-20|2013-04-23|Carefusion 212, Llc|Blower assembly with integral injection molded suspension mount|

US20070251527A1|2006-04-21|2007-11-01|Tiara Medical Systems, Inc.|Self-contained respiratory therapy apparatus for enhanced patient compliance and therapeutic efficacy|

WO2007149446A2|2006-06-16|2007-12-27|Aeiomed, Inc.|Modular positive airway pressure therapy apparatus and methods|

US20080006275A1|2006-07-07|2008-01-10|Steven Nickelson|Composite masks and methods for positive airway pressure therapies|

EP2063945B1|2006-09-07|2019-07-03|ResMed Ltd.|Mask and flow generator system|

US20080091090A1|2006-10-12|2008-04-17|Kenneth Shane Guillory|Self-contained surface physiological monitor with adhesive attachment|

US8028695B2|2006-11-30|2011-10-04|The General Electric Company|Apparatus and system for reducing mechanical ventilator noise|

US20080178879A1|2007-01-29|2008-07-31|Braebon Medical Corporation|Impeller for a wearable positive airway pressure device|

US20080216831A1|2007-03-08|2008-09-11|Mcginnis William J|Standalone cpap device and method of using|

JP5468747B2|2007-06-05|2014-04-09|レスメド・モーター・テクノロジーズ・インコーポレーテッド|Blower with bearing tube|

US9743859B2|2007-06-15|2017-08-29|Cardiac Pacemakers, Inc.|Daytime/nighttime respiration rate monitoring|

US20090065005A1|2007-09-06|2009-03-12|Ades Abraham J|Nose mask assembly to be worn during sleep having a suspension support bracket and a retractable line|

US8011362B2|2007-09-17|2011-09-06|Adams Phillip M|Compact continuous positive airway pressure apparatus and method|

US20090078258A1|2007-09-21|2009-03-26|Bowman Bruce R|Pressure regulation methods for positive pressure respiratory therapy|

US20090078255A1|2007-09-21|2009-03-26|Bowman Bruce R|Methods for pressure regulation in positive pressure respiratory therapy|

NZ585029A|2008-01-31|2011-07-29|Resmed Ltd|Respiratory apparatus with the flow generator casing mounted on the wearer's head|

CN101618247B|2008-07-03|2012-05-16|周常安|Expansible gas delivery system|

US8453640B2|2008-11-12|2013-06-04|Resmed Limited|Positive airway pressure device|

US8517017B2|2009-01-08|2013-08-27|Hancock Medical, Inc.|Self-contained, intermittent positive airway pressure systems and methods for treating sleep apnea, snoring, and other respiratory disorders|

US20140144445A1|2009-01-08|2014-05-29|Hancock Medical|Substantially Constant Positive Airway Pressure Systems and Methods for Treating Sleep Apnea, Snoring, and Other Respiratory Disorders|

US8355769B2|2009-03-17|2013-01-15|Advanced Brain Monitoring, Inc.|System for the assessment of sleep quality in adults and children|

WO2010107913A2|2009-03-17|2010-09-23|Corventis, Inc.|Adherent device with oximeter and physiological sensors|

US8672854B2|2009-05-20|2014-03-18|Sotera Wireless, Inc.|System for calibrating a PTT-based blood pressure measurement using arm height|

US8437970B2|2009-06-05|2013-05-07|Apple Inc.|Restoring and storing magnetometer calibration data|

NZ598152A|2009-08-28|2014-02-28|Resmed Ltd|Pap system|

US8397725B2|2009-09-04|2013-03-19|Designwise Medical|Respiratory treatment delivery system|

US9155857B2|2009-10-20|2015-10-13|Human Design Medical, Inc.|CPAP system with heat moisture exchange and multiple channel hose|

AU2010310736B2|2009-10-20|2015-03-05|Deshum Medical, Llc|Integrated positive airway pressure apparatus|

US20120298099A1|2009-10-20|2012-11-29|Deshum Medical, Llc|Docking system for a cpap machine|

US8409108B2|2009-11-05|2013-04-02|Inovise Medical, Inc.|Multi-axial heart sounds and murmur detection for hemodynamic-condition assessment|

BR112012017166A2|2009-12-23|2016-03-15|Delta Dansk Elektronik Lys Og Akustik|monitoring device|

US20110295083A1|2009-12-31|2011-12-01|Doelling Eric N|Devices, systems, and methods for monitoring, analyzing, and/or adjusting sleepconditions|

WO2011127407A1|2010-04-08|2011-10-13|Arm Medical Devices Inc.|Pressurized trachea cuff control arrangement|

EP2608836B1|2010-08-27|2018-03-28|Koninklijke Philips N.V.|Portable humidification system and adaptor therefore|

US8688187B2|2010-10-20|2014-04-01|Welch Allyn, Inc.|Pulse oximeter|

US8887718B2|2010-12-16|2014-11-18|Shikani Medical, Llc|Low profile heat and moisture exchanger device for tracheotomy and speaking valve|

US8336546B2|2011-02-08|2012-12-25|Hancock Medical, Inc.|Positive airway pressure system with head control|

US20150040908A1|2013-08-09|2015-02-12|Thomas G. Goff|Devices for portable airway pressure systems|WO2007117716A2|2006-04-10|2007-10-18|Aeiomed, Inc.|Apparatus and methods for administration of positive airway pressure therapies|

US8517017B2|2009-01-08|2013-08-27|Hancock Medical, Inc.|Self-contained, intermittent positive airway pressure systems and methods for treating sleep apnea, snoring, and other respiratory disorders|

US9381106B2|2010-04-23|2016-07-05|Invictus Medical, Inc.|Cranial position orientation detection method and apparatus for pediatric patients|

WO2012094230A2|2011-01-03|2012-07-12|Somnetics Global Pte. Ltd.|Positive airway pressure therapy apparatus and methods|

US8336546B2|2011-02-08|2012-12-25|Hancock Medical, Inc.|Positive airway pressure system with head control|

US9737676B2|2011-11-02|2017-08-22|Vyaire Medical Capital Llc|Ventilation system|

US9687618B2|2011-11-02|2017-06-27|Carefusion 207, Inc.|Ventilation harm index|

US9177109B2|2011-11-02|2015-11-03|Carefusion 207, Inc.|Healthcare facility ventilation management|

US9821129B2|2011-11-02|2017-11-21|Vyaire Medical Capital Llc|Ventilation management system|

CN103648567B|2012-03-09|2016-11-23|汉考克医药公司|There is the positive airway pressure system that head position controls|

CN107320791B|2012-03-12|2022-02-08|史密夫及内修公开有限公司|Wound dressing apparatus for reduced pressure wound therapy|

US9058741B2|2012-06-29|2015-06-16|Carefusion 207, Inc.|Remotely accessing a ventilator|

US9327090B2|2012-06-29|2016-05-03|Carefusion 303, Inc.|Respiratory knowledge portal|

US9352110B2|2012-06-29|2016-05-31|Carefusion 207, Inc.|Ventilator suction management|

US9072849B2|2012-06-29|2015-07-07|Carefusion 207, Inc.|Modifying ventilator operation based on patient orientation|

CA2897883A1|2013-01-14|2014-07-17|University Health Network|Mask and method for breathing disorder identification, characterization and/or diagnosis|

WO2014117179A1|2013-01-28|2014-07-31|Hancock Medical, Inc.|Position control devices and methods for use with positive airway pressure systems|

WO2014150744A1|2013-03-15|2014-09-25|Hancock Medical, Inc.|Positive airway pressure systems|

EP3110487B1|2014-02-26|2019-11-20|Koninklijke Philips N.V.|Patient interface with automatic position adjustment|

WO2016028525A1|2014-08-18|2016-02-25|Hancock Medical, Inc.|Portable pap device with humidification|

EP3226981A4|2014-12-04|2018-08-15|ResMed Limited|Wearable device for delivering air|

EP3552649A1|2015-04-02|2019-10-16|Hill-Rom Services PTE. LTD.|Pressure control of respiratory device|

ES2585851B1|2015-04-07|2017-06-14|Tecnicas Biomedicas Para La Salud, S.L.|AIR DRIVING DEVICE FOR PROVIDING ASSISTED VENTILATION DURING SPONTANEOUS BREATHING|

EP3457926A4|2016-05-19|2020-09-09|Hancock Medical, Inc.|Positional obstructive sleep apnea detection system|

IT201700086905A1|2017-07-28|2019-01-28|Amiko S R L|Accessory for inhaler, inhaler and method for detecting a drug administration process|

EP3687609A1|2017-09-29|2020-08-05|Koninklijke Philips N.V.|Pressure support device and method of providing an alert for non-effective pressure compensation regimen|

EP3852852A1|2018-09-21|2021-07-28|Koninklijke Philips N.V.|Radio frequency powered airway pressure support device|

CN113877033B|2021-12-09|2022-02-18|南京舒普思达医疗设备有限公司|Breathing machine regulation and control method and system based on sleep characteristics|

法律状态:
2014-04-24| NB| Applications allowed - extensions of time section 223(2)|Free format text: THE TIME IN WHICH TO FILE CONVENTION APPLICATION HAS BEEN EXTENDED TO 08 APR 2012 . |

2016-12-08| FGA| Letters patent sealed or granted (standard patent)|

2020-07-02| PC| Assignment registered|Owner name: RESMED INC Free format text: FORMER OWNER(S): HANCOCK MEDICAL, INC. |

优先权:

申请号 | 申请日 | 专利标题

US201161440685P| true| 2011-02-08|2011-02-08||

US61/440,685||2011-02-08||

US13/244,834||2011-09-23||

US13/244,834|US8327846B2|2011-02-08|2011-09-26|Positive airway pressure system with head position control|

PCT/US2012/028519|WO2013133850A1|2012-03-09|2012-03-09|Positive airway pressure system with head position control|

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